Page last updated: 2024-09-05

organophosphonates and 6-(bromomethylene)tetrahydro-3-(1-naphthaleneyl)-2h-pyran-2-one

organophosphonates has been researched along with 6-(bromomethylene)tetrahydro-3-(1-naphthaleneyl)-2h-pyran-2-one in 17 studies

Compound Research Comparison

Studies
(organophosphonates)
Trials
(organophosphonates)
Recent Studies (post-2010)
(organophosphonates)
Studies
(6-(bromomethylene)tetrahydro-3-(1-naphthaleneyl)-2h-pyran-2-one)
Trials
(6-(bromomethylene)tetrahydro-3-(1-naphthaleneyl)-2h-pyran-2-one)
Recent Studies (post-2010) (6-(bromomethylene)tetrahydro-3-(1-naphthaleneyl)-2h-pyran-2-one)
9,9688803,596195030

Protein Interaction Comparison

ProteinTaxonomyorganophosphonates (IC50)6-(bromomethylene)tetrahydro-3-(1-naphthaleneyl)-2h-pyran-2-one (IC50)
Fatty-acid amide hydrolase 1Homo sapiens (human)0.8

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (11.76)18.2507
2000's14 (82.35)29.6817
2010's1 (5.88)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ginalis, E; Greco, R; Haimovich, B; Ji, P; Kramer, R1
Akiba, S; Hayama, M; Kume, K; Mizunaga, S; Sato, T1
Fujita, S; Ikegaya, Y; Matsuki, N; Nishikawa, M; Nishiyama, N1
Boilard, E; Surette, ME1
Han, C; Shelhamer, JH; Wu, T1
Beckett, CS; Cummings, BS; Kinsey, GR; McHowat, J; Saavedra, G; Schnellmann, RG; Zhang, W1
Forlenza, OV; Gattaz, WF; Mendes, CT; Schaeffer, EL1
Gattaz, WF; Schaeffer, EL1
Schultz, C; Wichmann, O; Wittbrodt, J1
Alaux, S; Cummings, BS; Martel, MA; Massicotte, G; Ménard, C; Patenaude, C1
Chechneva, O; Reiser, G; Reymann, KG; Strokin, M1
McHowat, J; Portell, C; Rickard, A; Vinson, S1
Forlenza, OV; Gattaz, WF; Marie, SK; Mendes, CT1
Calzada, C; Ibrahim, S; Lagarde, M; Ponsin, G; Pruneta-Deloche, V1
Burgunder, JM; Farooqui, AA; Lee, LY; Ong, WY1
Cummings, BS; Franklin, JL; Monian, P; Peterson, B; Stovall, K1
Bachmann, S; Bleich, M; Daigeler, AL; Ferreri, NR; Himmerkus, N; Kahl, T; Mrowka, R; Mutig, K; Neymeyer, H; Paliege, A; Roeschel, T; Seidel, S; Wilson, BS1

Other Studies

17 other study(ies) available for organophosphonates and 6-(bromomethylene)tetrahydro-3-(1-naphthaleneyl)-2h-pyran-2-one

ArticleYear
Phospholipase A2 enzymes regulate alpha IIb beta3-mediated, but not Fc gammaRII receptor-mediated, pp125FAK phosphorylation in platelets.
    Thrombosis and haemostasis, 1999, Volume: 81, Issue:4

    Topics: Arachidonic Acid; Arachidonic Acids; Blood Platelets; Cell Adhesion; Cell Adhesion Molecules; Fibrinogen; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Immunoglobulin G; Naphthalenes; Organophosphonates; Phosphodiesterase Inhibitors; Phospholipases A; Phospholipases A2; Phosphorylation; Platelet Glycoprotein GPIIb-IIIa Complex; Protein-Tyrosine Kinases; Pyrones; Receptors, IgG

1999
Involvement of group VI Ca2+-independent phospholipase A2 in protein kinase C-dependent arachidonic acid liberation in zymosan-stimulated macrophage-like P388D1 cells.
    The Journal of biological chemistry, 1999, Jul-09, Volume: 274, Issue:28

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Diglycerides; Egtazic Acid; Group VI Phospholipases A2; Indoles; Leukemia P388; Maleimides; Mice; Naphthalenes; Oligonucleotides, Antisense; Organophosphonates; Phospholipases A; Phospholipases A2; Protein Kinase C; Pyrones; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Zymosan

1999
Docosahexaenoic acid improves long-term potentiation attenuated by phospholipase A(2) inhibitor in rat hippocampal slices.
    British journal of pharmacology, 2001, Volume: 132, Issue:7

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Docosahexaenoic Acids; Dose-Response Relationship, Drug; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; Naphthalenes; Organophosphonates; Phosphodiesterase Inhibitors; Phospholipases A; Pyrones; Rats; Rats, Wistar; Time Factors

2001
Anti-CD3 and concanavalin A-induced human T cell proliferation is associated with an increased rate of arachidonate-phospholipid remodeling. Lack of involvement of group IV and group VI phospholipase A2 in remodeling and increased susceptibility of prolif
    The Journal of biological chemistry, 2001, May-18, Volume: 276, Issue:20

    Topics: Acyltransferases; Apoptosis; Arachidonic Acid; Arachidonic Acids; CD3 Complex; Cell Division; Cells, Cultured; Concanavalin A; Enzyme Inhibitors; Humans; Imidazoles; Interleukin-2; Kinetics; Lymphocyte Activation; Muromonab-CD3; Naphthalenes; Oleic Acid; Organophosphonates; Organophosphorus Compounds; Phosphodiesterase Inhibitors; Phospholipases A; Phospholipases A2; Phospholipids; Pyrones; T-Lymphocytes; Thymidine

2001
Involvement of p38 and p42/44 MAP kinases and protein kinase C in the interferon-gamma and interleukin-1alpha-induced phosphorylation of 85-kDa cytosolic phospholipase A(2) in primary human bronchial epithelial cells.
    Cytokine, 2004, Jan-07, Volume: 25, Issue:1

    Topics: Arachidonic Acid; Arachidonic Acids; Bronchi; Cells, Cultured; Cytosol; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Flavonoids; Humans; Imidazoles; Interferon-gamma; Interleukin-1; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Naphthalenes; Organophosphonates; p38 Mitogen-Activated Protein Kinases; Phospholipases A; Phosphorylation; Protein Kinase C; Pyridines; Pyrones

2004
Identification and distribution of endoplasmic reticulum iPLA2.
    Biochemical and biophysical research communications, 2005, Feb-04, Volume: 327, Issue:1

    Topics: Amino Acid Sequence; Animals; Arachidonic Acids; Cell Line; Endoplasmic Reticulum; Enzyme Inhibitors; Female; Group VI Phospholipases A2; Humans; Kidney; Male; Microsomes; Molecular Sequence Data; Myocardium; Naphthalenes; Organ Specificity; Organophosphonates; Phospholipases A; Phospholipases A2; Protein Isoforms; Pyrones; Rabbits; Rats; RNA, Messenger; Sequence Alignment; Sequence Homology; Species Specificity

2005
Modulation of phospholipase A2 activity in primary cultures of rat cortical neurons.
    Journal of neural transmission (Vienna, Austria : 1996), 2005, Volume: 112, Issue:10

    Topics: Animals; Antigens, Bacterial; Arachidonic Acids; Cell Membrane; Cells, Cultured; Cerebral Cortex; Enzyme Activation; Enzyme Inhibitors; Female; Naphthalenes; Nerve Degeneration; Neurons; Organophosphonates; Phosphodiesterase Inhibitors; Phospholipases A; Phospholipases A2; Phospholipids; Pregnancy; Pyrones; Rats; Rats, Wistar

2005
Inhibition of calcium-independent phospholipase A2 activity in rat hippocampus impairs acquisition of short- and long-term memory.
    Psychopharmacology, 2005, Volume: 181, Issue:2

    Topics: Animals; Arachidonic Acids; Avoidance Learning; Exploratory Behavior; Group VI Phospholipases A2; Hippocampus; Ketones; Male; Memory, Short-Term; Motor Activity; Naphthalenes; Organophosphonates; Phospholipases A; Phospholipases A2; Pyrones; Rats; Rats, Wistar; Retention, Psychology

2005
A small-molecule FRET probe to monitor phospholipase A2 activity in cells and organisms.
    Angewandte Chemie (International ed. in English), 2006, Jan-09, Volume: 45, Issue:3

    Topics: Animals; Arachidonic Acids; Cells, Cultured; Dogs; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Fluorescence Resonance Energy Transfer; HeLa Cells; Humans; Hydrolysis; Kidney; Molecular Conformation; Molecular Weight; Naphthalenes; Organophosphonates; Oryzias; Phosphatidylethanolamines; Phospholipases A; Phospholipases A2; Pyrones; Stereoisomerism; Structure-Activity Relationship; Tissue Distribution

2006
A novel role for calcium-independent phospholipase A in alpha-amino-3-hydroxy-5-methylisoxazole-propionate receptor regulation during long-term potentiation.
    The European journal of neuroscience, 2006, Volume: 23, Issue:2

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arachidonic Acids; Blotting, Western; Calcium; Drug Interactions; Electric Stimulation; Gene Expression Regulation; Hippocampus; Immunoprecipitation; In Vitro Techniques; Long-Term Potentiation; Male; N-Methylaspartate; Naphthalenes; Neurons; Organophosphonates; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Phospholipases A; Protein Binding; Protein Isoforms; Pyrones; Rats; Receptors, AMPA; Synaptic Transmission; Time Factors

2006
Neuroprotection of rat hippocampal slices exposed to oxygen-glucose deprivation by enrichment with docosahexaenoic acid and by inhibition of hydrolysis of docosahexaenoic acid-containing phospholipids by calcium independent phospholipase A2.
    Neuroscience, 2006, Jun-30, Volume: 140, Issue:2

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Dentate Gyrus; Docosahexaenoic Acids; Enzyme Inhibitors; Hippocampus; Hydrolysis; Hypoxia-Ischemia, Brain; Male; Membrane Lipids; Naphthalenes; Neuroprotective Agents; Organ Culture Techniques; Organophosphonates; Phospholipases A; Phospholipases A2; Phospholipids; Prostaglandin Antagonists; Pyrones; Rats; Rats, Wistar

2006
Prostacyclin production in tryptase and thrombin stimulated human bladder endothelial cells: effect of pretreatment with phospholipase A2 and cyclooxygenase inhibitors.
    The Journal of urology, 2006, Volume: 176, Issue:4 Pt 1

    Topics: Arachidonic Acids; Blood Proteins; Cell Culture Techniques; Cyclooxygenase Inhibitors; Endothelial Cells; Epoprostenol; Hemostatics; Humans; Isoxazoles; Naphthalenes; Organophosphonates; Pyrazoles; Pyrones; Serine Endopeptidases; Sulfones; Thrombin; Tryptases; Urinary Bladder

2006
Inhibition of phospholipase A2 reduces neurite outgrowth and neuronal viability.
    Prostaglandins, leukotrienes, and essential fatty acids, 2007, Volume: 76, Issue:1

    Topics: Animals; Arachidonic Acids; Cell Survival; Cells, Cultured; Cerebral Cortex; Group VI Phospholipases A2; Hippocampus; Naphthalenes; Neurites; Neurons; Organophosphonates; Phospholipases A; Phospholipases A2; Pyrones; Rats

2007
The transfer of VLDL-associated phospholipids to activated platelets depends upon cytosolic phospholipase A2 activity.
    Journal of lipid research, 2007, Volume: 48, Issue:7

    Topics: Arachidonic Acids; Aspirin; Blood Platelets; Cytosol; Egtazic Acid; Estrenes; Humans; Lipoprotein Lipase; Lipoproteins, VLDL; Naphthalenes; Organophosphonates; Phospholipases A; Phospholipases A2; Phospholipid Transfer Proteins; Phospholipids; Platelet Activation; Pyrones; Pyrrolidinones; Thrombin; Umbelliferones

2007
Role of calcium-independent phospholipase A2 in cortex striatum thalamus cortex circuitry-enzyme inhibition causes vacuous chewing movements in rats.
    Psychopharmacology, 2007, Volume: 195, Issue:3

    Topics: Animals; Arachidonic Acids; Behavior, Animal; Benztropine; Calcium; Cerebral Cortex; Corpus Striatum; Dopamine Uptake Inhibitors; Drug Administration Routes; Enzyme Inhibitors; Male; Naphthalenes; Oligonucleotides, Antisense; Organ Specificity; Organophosphonates; Phosphodiesterase Inhibitors; Phospholipases A2, Calcium-Independent; Pyrones; Rats; Rats, Wistar; Stereotyped Behavior; Thalamus

2007
Alterations in phospholipid and fatty acid lipid profiles in primary neocortical cells during oxidant-induced cell injury.
    Chemico-biological interactions, 2008, Aug-11, Volume: 174, Issue:3

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cell Death; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fatty Acids, Unsaturated; Hydrogen Peroxide; Mice; Naphthalenes; Neocortex; Neurons; Organophosphonates; Oxidants; Phosphodiesterase Inhibitors; Phospholipases A; Phospholipids; Pyrones; Reactive Oxygen Species; Spectrometry, Mass, Electrospray Ionization; tert-Butylhydroperoxide; Thiobarbituric Acid Reactive Substances

2008
Group VIA phospholipase A2 is a target for vasopressin signaling in the thick ascending limb.
    American journal of physiology. Renal physiology, 2012, Apr-01, Volume: 302, Issue:7

    Topics: Animals; Antibodies; Arachidonic Acids; Cells, Cultured; Deamino Arginine Vasopressin; Down-Regulation; Fluorocarbons; Gene Expression; Group VI Phospholipases A2; Guinea Pigs; Humans; Isoenzymes; Ketones; Kidney Medulla; Loop of Henle; Male; Mice; Mice, Inbred C57BL; Naphthalenes; Organophosphonates; Phosphorylation; Pyrones; Rats; Rats, Brattleboro; Rats, Sprague-Dawley; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 1; Vasopressins

2012