Page last updated: 2024-09-05

organophosphonates and 3-amino-4-(3-hexylphenylamino)-4-oxobutylphosphonic acid

organophosphonates has been researched along with 3-amino-4-(3-hexylphenylamino)-4-oxobutylphosphonic acid in 27 studies

Compound Research Comparison

Studies (organophosphonates)	Trials (organophosphonates)	Recent Studies (post-2010) (organophosphonates)	Studies (3-amino-4-(3-hexylphenylamino)-4-oxobutylphosphonic acid)	Trials (3-amino-4-(3-hexylphenylamino)-4-oxobutylphosphonic acid)	Recent Studies (post-2010) (3-amino-4-(3-hexylphenylamino)-4-oxobutylphosphonic acid)
9,968	880	3,596	27	0	24

Research

Studies (27)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (7.41)	29.6817
2010's	23 (85.19)	24.3611
2020's	2 (7.41)	2.80

Authors

Authors	Studies
Cahalan, MD; Cheng, WC; Don, A; Gonzalez-Cabrera, PJ; Jo, E; Marsolais, D; Matheu, MP; Parker, I; Rosen, H; Sanna, MG; Wang, SK; Wei, SH; Wong, CH	1
Schultz, C	1
He, P; Qian, Y; Xu, S; Zhang, G	1
Chen, Z; Doyle, T; Finley, A; Salvemini, D	1
Chen, Z; Doyle, T; Obeid, LM; Salvemini, D	1
Aguilar, N; Aulí, M; Calbet, M; Dolgachev, V; Domènech, MT; Domínguez, M; Godessart, N; Kunkel, SL; López, R; Milligan, G; Mustafa, S; Pont, M; Prats, N; Tarrasón, G	1
Cahalan, SM; Clemons, B; Desale, H; Griffith, MT; Han, GW; Hanson, MA; Jo, E; Kuhn, P; Reinhart, G; Rosen, H; Roth, CB; Sanna, MG; Schuerer, SC; Scott, FL; Stevens, RC	1
Lima, S; Parrill, AL; Spiegel, S	1
Chi, XX; Li, C; Nicol, GD; Strong, JA; Xie, W; Zhang, JM	1
Alewijnse, AE; Buraschi, S; Chiodelli, P; Dell'era, P; Foglia, E; Mitola, S; Nicoli, S; Presta, M; Tobia, C; van Loenen, PB	1
Brown, JD; Francis, SA; Michel, T; Natarajan, P; Plutzky, J; Rader, DJ; Saghatelian, A; Tatematsu, S	1
Felding, BH; Gay, LJ; Nguyen, N; Rosen, H; Sarkisyan, G	1
Bieberich, E; Bryant, L; Chen, C; Chen, Z; Cuzzocrea, S; Doyle, T; Esposito, E; Janes, K; Kamocki, K; Li, C; Little, JW; Neumann, WL; Nicol, G; Obeid, L; Petrache, I; Salvemini, D; Snider, A	1
Haufe, G; Hermann, S; Keul, P; Levkau, B; Prasad, VP; Schäfers, M; Wagner, S	1
Ferreirós, N; Geisslinger, G; Henke, M; Linke, B; Scholich, K; Schreiber, Y; Stark, H; Suo, J; Zhang, DD; Zivkovic, A	1
Guerrero, M; Kays, J; Li, C; Li, JN; Nicol, GD	1
Attiori Essis, S; Cyr, M; Laurier-Laurin, ME; Massicotte, G; Pépin, É	1
Gao, P; Kang, Y; Li, Y; Ning, Z; Ren, T; Sun, M; Xiang, B; Xie, P; Zhu, W	1
Cotta-de-Almeida, V; Lemos, JP; Mendes-da-Cruz, DA; Messias, CV; Moreira, OC; Santana-Van-Vliet, E; Savino, W	1
Fu, Y; Han, W; Hao, J; Huang, D; Liu, Q; Shen, Y; Sheth, KN; Shi, FD; Shi, K; Sun, N; Wood, K	1
Klöckl, L; Schuchardt, M; Tölle, M; van der Giet, M; Wiedon, A; Zidek, W	1
Böhm, A; Dannenberg, L; Kelm, M; Knoop, B; Levkau, B; Polzin, A; Rauch, BH; Zeus, T; Zurek, M	1
Donahue, RR; Doolen, S; Grachen, CM; Iannitti, T; Shaw, BC; Taylor, BK	1
Fu, J; Gao, F; Gao, Y; Li, Y; Meng, F; Yang, C	1
Chung, H; Jo, DI; Jung, SH; Kim, B; Kim, SH; Ko, HM; Lee, DH; Lee, SH; Song, YK	1
Gräler, MH; Guntinas-Lichius, O; Jeya Paul, J; Thuy, AV; Weigel, C; Ziegler, AC	1
Birch, CA; Chen, B; Cisneros-Aguirre, M; Coronel, LJ; Gomez Menzies, PK; Grimsey, NJ; Lawson, MA; Lin, H; Molinar-Inglis, O; Nicholas, D; Orduña-Castillo, L; Patel, HH; Patwardhan, A; Trejo, J	1

Other Studies

27 other study(ies) available for organophosphonates and 3-amino-4-(3-hexylphenylamino)-4-oxobutylphosphonic acid

Article	Year
Enhancement of capillary leakage and restoration of lymphocyte egress by a chiral S1P1 antagonist in vivo. Nature chemical biology, 2006, Volume: 2, Issue:8 Topics: Anilides; Animals; Capillary Permeability; Cells, Cultured; CHO Cells; Cricetinae; Disease Models, Animal; Evans Blue; Humans; Lymph Nodes; Lymphocytes; Lysophospholipids; Mice; Mice, Inbred C57BL; Models, Biological; Organophosphonates; Phenotype; Pulmonary Edema; Receptors, Lysosphingolipid; Sphingosine; Stereoisomerism	2006
Lipid-induced phenotypes. Nature chemical biology, 2006, Volume: 2, Issue:8 Topics: Anilides; Animals; Binding Sites; Humans; Lysophospholipids; Models, Biological; Organophosphonates; Phenotype; Receptors, Lysosphingolipid; Signal Transduction; Sphingosine	2006
Sphingosine-1-phosphate prevents permeability increases via activation of endothelial sphingosine-1-phosphate receptor 1 in rat venules. American journal of physiology. Heart and circulatory physiology, 2010, Volume: 299, Issue:5 Topics: Anilides; Animals; Calcium; Capillary Permeability; Endothelium, Vascular; Female; Lysophospholipids; Mesentery; Models, Animal; Organophosphonates; Pyrazoles; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Lysosphingolipid; Sphingosine; Venules	2010
Role for peroxynitrite in sphingosine-1-phosphate-induced hyperalgesia in rats. Pain, 2011, Volume: 152, Issue:3 Topics: Acetophenones; Anilides; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Hyperalgesia; Lysophospholipids; Male; Metalloporphyrins; NG-Nitroarginine Methyl Ester; Organophosphonates; Oxadiazoles; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Lysosphingolipid; Sphingosine; Thiophenes; Time Factors	2011
Sphingosine-1-phosphate acting via the S1P₁ receptor is a downstream signaling pathway in ceramide-induced hyperalgesia. Neuroscience letters, 2011, Jul-15, Volume: 499, Issue:1 Topics: Anilides; Animals; Ceramides; Hyperalgesia; Inflammation Mediators; Injections, Subcutaneous; Lysophospholipids; Male; Mice; Organophosphonates; Rats; Rats, Sprague-Dawley; Receptors, Lysosphingolipid; Signal Transduction; Sphingosine	2011
The sphingosine-1-phosphate receptor-1 antagonist, W146, causes early and short-lasting peripheral blood lymphopenia in mice. International immunopharmacology, 2011, Volume: 11, Issue:11 Topics: Anilides; Animals; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Chemotaxis; Flow Cytometry; Lymph Nodes; Lymphocyte Count; Lymphocytes; Lymphopenia; Male; Mice; Organophosphonates; Receptors, Lysosphingolipid; Thymus Gland; Time Factors	2011
Crystal structure of a lipid G protein-coupled receptor. Science (New York, N.Y.), 2012, Feb-17, Volume: 335, Issue:6070 Topics: Anilides; Binding Sites; Crystallography, X-Ray; Models, Molecular; Muramidase; Mutagenesis; Organophosphonates; Protein Conformation; Receptors, Lysosphingolipid; Recombinant Fusion Proteins	2012
Structure of the first sphingosine 1-phosphate receptor. Science signaling, 2012, May-22, Volume: 5, Issue:225 Topics: Anilides; Binding Sites; Crystallography, X-Ray; Drug Design; Humans; Indans; Lysophospholipids; Models, Molecular; Organophosphonates; Oxadiazoles; Protein Binding; Protein Conformation; Receptors, Lysosphingolipid; Sphingosine	2012
Sphingosine 1-phosphate receptor 2 antagonist JTE-013 increases the excitability of sensory neurons independently of the receptor. Journal of neurophysiology, 2012, Volume: 108, Issue:5 Topics: Action Potentials; Analysis of Variance; Anilides; Animals; Capsaicin; Cell Line, Tumor; Cell Movement; Dinoprostone; Dose-Response Relationship, Drug; Drug Interactions; Ganglia, Spinal; Guanosine Diphosphate; Hyperalgesia; Lysophospholipids; Male; Melanoma; Mice; Organophosphonates; Pain Threshold; Patch-Clamp Techniques; Pertussis Toxin; Pyrazoles; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Lysosphingolipid; Sensory Receptor Cells; Sensory System Agents; Sphingosine; Thionucleotides; Time Factors; Wound Healing	2012
Sphingosine-1-phosphate receptor-1 controls venous endothelial barrier integrity in zebrafish. Arteriosclerosis, thrombosis, and vascular biology, 2012, Volume: 32, Issue:9 Topics: Anilides; Animals; Animals, Genetically Modified; Antigens, CD; Cadherins; Capillary Permeability; CHO Cells; Cricetinae; Cricetulus; Endothelial Cells; Gene Expression Regulation, Developmental; Green Fluorescent Proteins; Human Umbilical Vein Endothelial Cells; Humans; Membrane Proteins; Morpholinos; Oligonucleotides, Antisense; Organophosphonates; Phosphoproteins; Receptor, EphB4; Receptors, Lysosphingolipid; RNA Interference; Sphingosine-1-Phosphate Receptors; Tight Junctions; Transfection; Veins; Zebrafish; Zebrafish Proteins; Zonula Occludens-1 Protein	2012
Endothelial lipase is a critical determinant of high-density lipoprotein-stimulated sphingosine 1-phosphate-dependent signaling in vascular endothelium. Arteriosclerosis, thrombosis, and vascular biology, 2013, Volume: 33, Issue:8 Topics: Anilides; Animals; Cell Movement; Cell Proliferation; Cells, Cultured; Cholesterol; Endothelium, Vascular; Lipase; Lipoproteins, HDL; Lysophospholipids; Mice; Mice, Knockout; Neovascularization, Physiologic; Nitric Oxide Synthase Type III; Organophosphonates; Phosphorylation; Proto-Oncogene Proteins c-akt; Receptors, Lysosphingolipid; RNA, Small Interfering; Signal Transduction; Sphingosine	2013
Host endothelial S1PR1 regulation of vascular permeability modulates tumor growth. American journal of physiology. Cell physiology, 2014, Jul-01, Volume: 307, Issue:1 Topics: Anilides; Animals; Breast Neoplasms; Capillary Permeability; Endothelial Cells; Female; Green Fluorescent Proteins; Lung Neoplasms; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neoplastic Cells, Circulating; Neovascularization, Pathologic; Organophosphonates; Receptors, Lysosphingolipid; Signal Transduction; Sphingosine-1-Phosphate Receptors; Time Factors; Tumor Burden	2014
The development and maintenance of paclitaxel-induced neuropathic pain require activation of the sphingosine 1-phosphate receptor subtype 1. The Journal of biological chemistry, 2014, Jul-25, Volume: 289, Issue:30 Topics: Anilides; Animals; Antineoplastic Agents, Phytogenic; Cytokines; Enzyme Activation; Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Indans; Lysophospholipids; Male; Neuralgia; Organophosphonates; Oxadiazoles; Paclitaxel; Propylene Glycols; Rats; Rats, Sprague-Dawley; Receptors, Lysosphingolipid; Signal Transduction; Sphingosine; Sphingosine-1-Phosphate Receptors; Thiazoles; Thiophenes	2014
Synthesis of fluorinated analogues of sphingosine-1-phosphate antagonists as potential radiotracers for molecular imaging using positron emission tomography. Bioorganic & medicinal chemistry, 2014, Oct-01, Volume: 22, Issue:19 Topics: Anilides; Animals; Cells, Cultured; CHO Cells; Cricetulus; Dose-Response Relationship, Drug; Fluorine Radioisotopes; Halogenation; Humans; Male; Mice; Mice, Inbred C57BL; Molecular Imaging; Molecular Structure; Organophosphonates; Positron-Emission Tomography; Radiopharmaceuticals; Receptors, Lysosphingolipid; Structure-Activity Relationship; Tissue Distribution	2014
Antinociceptive effects of FTY720 during trauma-induced neuropathic pain are mediated by spinal S1P receptors. Biological chemistry, 2015, Volume: 396, Issue:6-7 Topics: Analgesics; Anilides; Animals; In Situ Hybridization; Lysophospholipids; Male; Mice; Neuralgia; Organophosphates; Organophosphonates; Phosphotransferases (Alcohol Group Acceptor); Receptors, Lysosphingolipid; Signal Transduction; Sphingosine; Wounds and Injuries	2015
Sphingosine 1-phosphate enhances the excitability of rat sensory neurons through activation of sphingosine 1-phosphate receptors 1 and/or 3. Journal of neuroinflammation, 2015, Apr-12, Volume: 12 Topics: Action Potentials; Anilides; Animals; Cells, Cultured; Dinoprostone; Enzyme Inhibitors; Fingolimod Hydrochloride; Ganglia, Spinal; Gene Expression Regulation; Immunosuppressive Agents; Lysophospholipids; Mice; Mice, Inbred C57BL; Organophosphonates; Rats; Rats, Sprague-Dawley; Receptors, Lysosphingolipid; RNA, Small Interfering; Sensory Receptor Cells; Sphingosine; Sphingosine-1-Phosphate Receptors; Thiazolidines	2015
GluN2B-containing NMDA receptors are upregulated in plasma membranes by the sphingosine-1-phosphate analog FTY720P. Brain research, 2015, Oct-22, Volume: 1624 Topics: Analysis of Variance; Anilides; Animals; Biotinylation; Cell Membrane; Enzyme Inhibitors; Hippocampus; In Vitro Techniques; Lysophospholipids; Male; Organophosphates; Organophosphonates; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptors, Lysosphingolipid; Receptors, N-Methyl-D-Aspartate; Sphingosine; Sphingosine-1-Phosphate Receptors; src-Family Kinases; Time Factors; Transcriptional Activation; Up-Regulation	2015
S1PR1 expression correlates with inflammatory responses to Newcastle disease virus infection. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases, 2016, Volume: 37 Topics: Anilides; Animals; Cells, Cultured; Chick Embryo; Cytokines; Fibroblasts; Newcastle Disease; Newcastle disease virus; Organophosphonates; Poultry Diseases; Receptors, Lysosphingolipid; Up-Regulation	2016
Sphingosine-1-Phosphate Induces Dose-Dependent Chemotaxis or Fugetaxis of T-ALL Blasts through S1P1 Activation. PloS one, 2016, Volume: 11, Issue:1 Topics: Anilides; Cell Line, Tumor; Chemotaxis; Gene Expression Regulation, Leukemic; Humans; Lysophospholipids; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Organophosphonates; Phosphorylation; Proto-Oncogene Proteins c-akt; rac1 GTP-Binding Protein; Receptors, Lysosphingolipid; RNA, Messenger; Signal Transduction; Sphingosine; T-Lymphocytes	2016
Selective Sphingosine-1-Phosphate Receptor 1 Modulation Attenuates Experimental Intracerebral Hemorrhage. Stroke, 2016, Volume: 47, Issue:7 Topics: Anilides; Animals; Apoptosis; Blood-Brain Barrier; Brain Edema; Cerebral Hemorrhage; Cytokines; DNA-Binding Proteins; Drug Evaluation, Preclinical; Lymphocyte Subsets; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microglia; Neurons; Organophosphonates; Receptors, Lysosphingolipid; Sphingosine-1-Phosphate Receptors	2016
Regulation of endothelial nitric oxide synthase activation in endothelial cells by S1P1 and S1P3. Biochemical and biophysical research communications, 2016, 08-05, Volume: 476, Issue:4 Topics: Anilides; beta-Alanine; Endothelial Cells; Enzyme Activation; Gene Knockdown Techniques; Human Umbilical Vein Endothelial Cells; Humans; Nitric Oxide; Nitric Oxide Synthase Type III; Organophosphates; Organophosphonates; Phosphorylation; Phosphoserine; Proto-Oncogene Proteins c-akt; Receptors, Lysosphingolipid; RNA, Small Interfering; Signal Transduction; Sphingosine; Sphingosine-1-Phosphate Receptors; Thiazolidines; Thiophenes	2016
Aspirin Inhibits Platelet-Derived Sphingosine-1-Phosphate Induced Endothelial Cell Migration. Pharmacology, 2018, Volume: 101, Issue:1-2 Topics: Anilides; Aspirin; Blood Platelets; Cell Movement; Cells, Cultured; Human Umbilical Vein Endothelial Cells; Humans; Lysophospholipids; Organophosphonates; Receptors, Lysosphingolipid; Sphingosine	2018
Fingolimod reduces neuropathic pain behaviors in a mouse model of multiple sclerosis by a sphingosine-1 phosphate receptor 1-dependent inhibition of central sensitization in the dorsal horn. Pain, 2018, Volume: 159, Issue:2 Topics: Anilides; Animals; Central Nervous System Sensitization; Disease Models, Animal; eIF-2 Kinase; Female; Fingolimod Hydrochloride; Immunosuppressive Agents; Male; Mice; Mice, Inbred C57BL; Motor Activity; Multiple Sclerosis; Myelin-Oligodendrocyte Glycoprotein; Neuralgia; Organophosphonates; Oxadiazoles; Pain Threshold; Peptide Fragments; Receptors, Lysosphingolipid; Sphingosine-1-Phosphate Receptors; Spinal Cord; Spinal Nerve Roots; Subcellular Fractions; Thiophenes	2018
The Sphingosine 1-Phosphate Analogue FTY720 Alleviates Seizure-induced Overexpression of P-Glycoprotein in Rat Hippocampus. Basic & clinical pharmacology & toxicology, 2018, Volume: 123, Issue:1 Topics: Anilides; Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclooxygenase 2; Disease Models, Animal; Drug Resistant Epilepsy; Fingolimod Hydrochloride; Hippocampus; Humans; Immunosuppressive Agents; Injections, Intraperitoneal; Lysophospholipids; Male; Organophosphonates; Phenytoin; Pilocarpine; Rats; Rats, Sprague-Dawley; Receptors, Lysosphingolipid; Sphingosine; Sphingosine-1-Phosphate Receptors; Up-Regulation	2018
Association between sphingosine-1-phosphate-induced signal transduction via mitogen-activated protein kinase pathways and keloid formation. Archives of dermatological research, 2019, Volume: 311, Issue:9 Topics: Adult; Anilides; Anthracenes; Cell Line; Collagen Type I; Collagen Type I, alpha 1 Chain; Female; Fibroblasts; Flavonoids; Humans; Keloid; Lysophospholipids; Male; MAP Kinase Signaling System; Middle Aged; Mitogen-Activated Protein Kinases; Organophosphonates; Phosphorylation; Pyrazoles; Pyridines; Signal Transduction; Sphingosine; Sphingosine-1-Phosphate Receptors; Young Adult	2019
Validation of a monoclonal antibody directed against the human sphingosine 1-phosphate receptor type 1. Journal of immunological methods, 2021, Volume: 490 Topics: Anilides; Animals; Antibodies, Monoclonal; B-Lymphocytes; Burkitt Lymphoma; Endothelial Cells; Gene Expression Regulation; Human Umbilical Vein Endothelial Cells; Humans; Immunoglobulin M; Mice; Organ Specificity; Organophosphonates; Palatine Tonsil; Sphingosine-1-Phosphate Receptors; T-Lymphocytes	2021
aPC/PAR1 confers endothelial anti-apoptotic activity via a discrete, β-arrestin-2-mediated SphK1-S1PR1-Akt signaling axis. Proceedings of the National Academy of Sciences of the United States of America, 2021, 12-07, Volume: 118, Issue:49 Topics: Anilides; Apoptosis; beta-Arrestin 2; Endothelial Cells; Enzyme Inhibitors; Gene Expression Regulation; Heterocyclic Compounds, 3-Ring; Humans; Lactones; Methanol; Organophosphonates; Phosphotransferases (Alcohol Group Acceptor); Platelet Aggregation Inhibitors; Protein C; Proto-Oncogene Proteins c-akt; Pyridines; Pyrrolidines; Receptor, PAR-1; Sphingosine-1-Phosphate Receptors; Sulfones	2021