organophosphonates has been researched along with 3-(n-acetyl-n-hydroxy)aminopropylphosphonic acid in 5 studies
| Studies (organophosphonates) | Trials (organophosphonates) | Recent Studies (post-2010) (organophosphonates) | Studies (3-(n-acetyl-n-hydroxy)aminopropylphosphonic acid) | Trials (3-(n-acetyl-n-hydroxy)aminopropylphosphonic acid) | Recent Studies (post-2010) (3-(n-acetyl-n-hydroxy)aminopropylphosphonic acid) |
|---|---|---|---|---|---|
| 9,968 | 880 | 3,596 | 50 | 0 | 28 |
| Protein | Taxonomy | organophosphonates (IC50) | 3-(n-acetyl-n-hydroxy)aminopropylphosphonic acid (IC50) |
|---|---|---|---|
| 1-deoxy-D-xylulose 5-phosphate reductoisomerase | Mycolicibacterium smegmatis MC2 155 | 0.32 | |
| 1-deoxy-D-xylulose 5-phosphate reductoisomerase | Escherichia coli K-12 | 0.0365 | |
| 1-deoxy-D-xylulose 5-phosphate reductoisomerase | Mycobacterium tuberculosis H37Rv | 1.275 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Altincicek, B; Beck, E; Dreiseidler, E; Jomaa, H; Reichenberg, A; Sanderbrand, S; Schlitzer, M; Weidemeyer, C; Wiesner, J | 1 |
| Fokin, AA; Gunchenko, PA; Hintz, M; Jomaa, H; Reichenberg, A; Rodionov, VN; Schreiner, PR; Wiesner, J; Yurchenko, AG; Yurchenko, RI | 1 |
| Andaloussi, M; Björkelid, C; Iyer, H; Karlén, A; Larhed, M; Lindh, M; Suresh, S; Wieckowska, A | 1 |
| Grosdemange-Billiard, C; Ponaire, S; Rohmer, M; Tritsch, D; Zinglé, C | 1 |
| Adeyemi, CM; Hoppe, HC; Isaacs, M; Kaye, PT; Krause, RW; Mnkandhla, D | 1 |
5 other study(ies) available for organophosphonates and 3-(n-acetyl-n-hydroxy)aminopropylphosphonic acid
| Article | Year |
|---|---|
Diaryl ester prodrugs of FR900098 with improved in vivo antimalarial activity.
Topics: Aldose-Ketose Isomerases; Animals; Antimalarials; Disease Models, Animal; Fosfomycin; Malaria; Mice; Multienzyme Complexes; Organophosphonates; Oxidoreductases; Plasmodium; Prodrugs; Treatment Outcome | 2001 |
Synthesis of the antimalarial drug FR900098 utilizing the nitroso-ene reaction.
Topics: Antimalarials; Fosfomycin; Hydrogenation; Molecular Structure; Nitroso Compounds; Organophosphonates; Structure-Activity Relationship | 2007 |
Substitution of the phosphonic acid and hydroxamic acid functionalities of the DXR inhibitor FR900098: an attempt to improve the activity against Mycobacterium tuberculosis.
Topics: Aldose-Ketose Isomerases; Antitubercular Agents; Crystallography, X-Ray; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fosfomycin; Hydroxamic Acids; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Multienzyme Complexes; Mycobacterium tuberculosis; Organophosphonates; Oxidoreductases; Stereoisomerism; Structure-Activity Relationship | 2011 |
Growth inhibition of Mycobacterium smegmatis by prodrugs of deoxyxylulose phosphate reducto-isomerase inhibitors, promising anti-mycobacterial agents.
Topics: Aldose-Ketose Isomerases; Anti-Bacterial Agents; Enzyme Inhibitors; Fosfomycin; Hydrophobic and Hydrophilic Interactions; Kinetics; Microbial Viability; Multienzyme Complexes; Mycobacterium smegmatis; Organophosphonates; Oxazines; Oxidoreductases; Prodrugs; Xanthenes | 2012 |
Synthesis and antimalarial activity of N-benzylated (N-arylcarbamoyl)alkylphosphonic acid derivatives.
Topics: Aldose-Ketose Isomerases; Amides; Antimalarials; Fosfomycin; HeLa Cells; Humans; Organophosphonates; Plasmodium falciparum; Structure-Activity Relationship | 2016 |