organophosphonates has been researched along with 2-amino-3-(5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl)propionic acid in 5 studies
| Studies (organophosphonates) | Trials (organophosphonates) | Recent Studies (post-2010) (organophosphonates) | Studies (2-amino-3-(5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl)propionic acid) | Trials (2-amino-3-(5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl)propionic acid) | Recent Studies (post-2010) (2-amino-3-(5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl)propionic acid) |
|---|---|---|---|---|---|
| 9,968 | 880 | 3,596 | 9 | 0 | 2 |
| Protein | Taxonomy | organophosphonates (IC50) | 2-amino-3-(5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl)propionic acid (IC50) |
|---|---|---|---|
| Chain A, Glutamate receptor 2 | Rattus norvegicus (Norway rat) | 12.2 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Anker, C; Egebjerg, J; Krogsgaard-Larsen, P; Madsen, U; Rasmussen, JS; Traynelis, SF; Wahl, P | 1 |
| Dai, WM; Ebert, B; Lambert, JD; Madsen, U | 1 |
| Brehm, L; Egebjerg, J; Johansen, TN; Krogsgaard-Larsen, P; Madsen, U; Møller, EH; Stensbøl, TB | 1 |
| Egebjerg, J; Gouaux, E; Greenwood, JR; Hogner, A; Kastrup, JS; Larsen, IK; Liljefors, T; Lunn, ML | 1 |
| Ahring, PK; Egebjerg, J; Gajhede, M; Hald, H; Kastrup, JS; Liljefors, T; Madsen, U; Naur, P; Pickering, DS; Schousboe, A; Sprogøe, D; Timmermann, DB | 1 |
5 other study(ies) available for organophosphonates and 2-amino-3-(5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl)propionic acid
| Article | Year |
|---|---|
Antagonist properties of a phosphono isoxazole amino acid at glutamate R1-4 (R,S)-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid receptor subtypes.
Topics: Animals; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Female; Humans; Isoxazoles; Organophosphonates; Receptors, AMPA; Recombinant Proteins; Xenopus laevis | 1998 |
Studies of the antagonist actions of (RS)-2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl] propionic acid (ATPO) on non-NMDA receptors in cultured rat neurones.
Topics: Adrenal Cortex Hormones; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Cells, Cultured; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamates; Isoxazoles; Kainic Acid; Neurons; Organophosphonates; Rats; Rats, Sprague-Dawley; Receptors, AMPA | 1998 |
Resolution, absolute stereochemistry, and enantiopharmacology of the GluR1-4 and GluR5 antagonist 2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl]propionic acid.
Topics: Animals; Crystallography, X-Ray; Excitatory Amino Acid Antagonists; Isoxazoles; Molecular Structure; Organophosphonates; Radioligand Assay; Rats; Receptors, Glutamate; Stereoisomerism | 1999 |
Competitive antagonism of AMPA receptors by ligands of different classes: crystal structure of ATPO bound to the GluR2 ligand-binding core, in comparison with DNQX.
Topics: Binding Sites; Crystallography, X-Ray; Excitatory Amino Acid Antagonists; Isoxazoles; Ligands; Models, Molecular; Organophosphonates; Quinoxalines; Receptors, AMPA | 2003 |
Partial agonism and antagonism of the ionotropic glutamate receptor iGLuR5: structures of the ligand-binding core in complex with domoic acid and 2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl]propionic acid.
Topics: Animals; Binding Sites; Crystallography, X-Ray; Dimerization; Humans; Isoxazoles; Kainic Acid; Ligands; Organophosphonates; Protein Binding; Protein Structure, Tertiary; Receptors, AMPA; Receptors, Kainic Acid | 2007 |