organophosphonates has been researched along with 1-anilino-8-naphthalenesulfonate in 33 studies
| Studies (organophosphonates) | Trials (organophosphonates) | Recent Studies (post-2010) (organophosphonates) | Studies (1-anilino-8-naphthalenesulfonate) | Trials (1-anilino-8-naphthalenesulfonate) | Recent Studies (post-2010) (1-anilino-8-naphthalenesulfonate) |
|---|---|---|---|---|---|
| 9,968 | 880 | 3,596 | 24,275 | 480 | 7,815 |
| Protein | Taxonomy | organophosphonates (IC50) | 1-anilino-8-naphthalenesulfonate (IC50) |
|---|---|---|---|
| Chain A, RNA-directed RNA polymerase NS5 | Dengue virus 2 16681-PDK53 | 100 | |
| Mitogen-activated protein kinase 14 | Homo sapiens (human) | 1.2 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (9.09) | 18.7374 |
| 1990's | 6 (18.18) | 18.2507 |
| 2000's | 10 (30.30) | 29.6817 |
| 2010's | 12 (36.36) | 24.3611 |
| 2020's | 2 (6.06) | 2.80 |
| Authors | Studies |
|---|---|
| Benkovic, SJ; Janda, KD; Lerner, RA | 1 |
| Engle, DE; Hendrickson, HS; Rustad, DG; Scattergood, EM | 1 |
| Cohen, EM; Polak, RL | 1 |
| Boots, JW; de Haas, GH; Dijkman, R; Egmond, MR; Mannesse, ML; Slotboom, AJ; van der Hijden, HT; Verheij, HM | 1 |
| Buono, G; Cambillau, C; Egloff, MP; Marguet, F; van Tilbeurgh, H; Verger, R | 1 |
| Anthonsen, T; Hult, K; Jones, TA; Kleywegt, GJ; Norin, M; Ohrner, N; Patkar, S; Uppenberg, J; Waagen, V | 1 |
| Haalck, L; Hermetter, A; Paltauf, F; Spener, F; Stadler, P; Zandonella, G | 1 |
| Cambillau, C; Canaan, S; Dupuis, L; Egloff, MP; Rivière, M; Roussel, A; Verger, R | 1 |
| Buono, G; Cavalier, JF; Ransac, S; Verger, R | 1 |
| Buono, G; Cavalier, JF; Verger, R | 1 |
| Bywater, RP; Jensen, MO; Peters, GH | 1 |
| Berna, P; Berti-Dupuis, L; Cambillau, C; Gruber, V; Miled, N; Rivière, M; Roussel, A; Spinelli, S; Verger, R | 1 |
| Hermetter, A; Oskolkova, OV | 1 |
| Dijkstra, DS; Dröge, MJ; Quax, WJ; Reetz, MT; Rüggeberg, CJ; Schimmel, J; van der Sloot, AM; Verhaert, RM | 1 |
| Hermetter, A; Oskolkova, OV; Saf, R; Zenzmaier, E | 1 |
| Berti-Dupuis, L; Buono, G; Bussetta, C; Cambillau, C; Canaan, S; Miled, N; Rivière, M; Roussel, A; Verger, R | 1 |
| Birner-Gruenberger, R; Hermetter, A; Riesenhuber, G; Saf, R; Schmidinger, H; Susani-Etzerodt, H | 1 |
| Birner-Gruenberger, R; Hermetter, A | 1 |
| Casida, JE; Chiu, S; Hudak, CS; Krauss, RM; Mangravite, LM; Nomura, DK; Ruby, MA | 1 |
| Birner-Gruenberger, R; Schittmayer, M; Viertler, M | 1 |
| Adibekian, A; Cravatt, BF; Martin, BR; Tully, SE; Wang, C | 1 |
| Amara, S; Carrière, F; Delorme, V; Record, M | 1 |
| Canaan, S; Carriere, F; Cavalier, JF; Delorme, V; Diomande, S; Malla, RK; Martin, BP; Point, V; Rath, NP; Spilling, CD | 1 |
| Bowie, JU; Korman, TP | 1 |
| Canaan, S; Carrière, F; Cavalier, JF; Malla, RK; Point, V; Spilling, CD | 1 |
| Chen, H; Chen, W; Liu, W; Liu, X; Qu, R; Tang, Q; Xu, Q; Yin, P | 1 |
| Brown, JD; Francis, SA; Michel, T; Natarajan, P; Plutzky, J; Rader, DJ; Saghatelian, A; Tatematsu, S | 1 |
| Amara, S; Carriere, F; Cazabat, M; Chapuy-Regaud, S; de Medina, P; Delton-Vandenbroucke, I; Izopet, J; Payre, B; Poirot, M; Record, M; Requena, M; Subra, C | 1 |
| Han, SY; Jin, Z; Lin, Y; Zhang, K; Zhang, L; Zheng, SP | 1 |
| Amara, S; Blangy, S; Cambillau, C; Carrière, F; Kontkanen, H; Mateos-Diaz, E; Nyyssölä, A; Roussel, A; Westerholm-Parvinen, A | 1 |
| Bialecka-Florjanczyk, E; Fabiszewska, AU; Krzyczkowska, J; Kurylowicz, A | 1 |
| Dhavan, P; Jadhav, BL; Ramana, MMV; Shaikh, S | 1 |
| Hrunyk, A; Koszelewski, D; Kowalczyk, P; Kramkowski, K; Lizut, R; Ostaszewski, R; Samsonowicz-Górski, J; Śmigielski, P; Szymczak, M; Wypych, A | 1 |
3 review(s) available for organophosphonates and 1-anilino-8-naphthalenesulfonate
| Article | Year |
|---|---|
Covalent inhibition of digestive lipases by chiral phosphonates.
Topics: Enzyme Inhibitors; Gastric Mucosa; Humans; Lactones; Lipase; Organophosphonates; Orlistat; Pancreas; Stereoisomerism | 2000 |
Activity-based proteomics of lipolytic enzymes.
Topics: Animals; Binding Sites; Biomarkers; Drug Design; Drug Evaluation, Preclinical; Enzyme Inhibitors; Fluorescent Dyes; Humans; Lipase; Organophosphonates; Protein Array Analysis; Proteomics; Sterol Esterase; Structure-Activity Relationship | 2007 |
Synthetic and Natural Lipase Inhibitors.
Topics: Animals; Boronic Acids; Enzyme Inhibitors; Fatty Acids; Humans; Lactones; Lipase; Obesity; Organophosphonates; Orlistat; Plant Extracts; Surface-Active Agents | 2018 |
30 other study(ies) available for organophosphonates and 1-anilino-8-naphthalenesulfonate
| Article | Year |
|---|---|
Catalytic antibodies with lipase activity and R or S substrate selectivity.
Topics: Animals; Antibodies, Monoclonal; Antibody Specificity; Antigens; Benzyl Alcohols; Catalysis; Esters; Haptens; Hemocyanins; Hydrolysis; Immunization; Kinetics; Lipase; Mice; Mice, Inbred A; Molecular Structure; Organophosphonates; Stereoisomerism; Substrate Specificity | 1989 |
The action of phospholipase C and lipase on black film bilayer membranes.
Topics: Animals; Binding Sites; Brain; Cattle; Cholesterol; Chromatography, Thin Layer; Clostridium perfringens; Egg Yolk; Electric Conductivity; Female; Hydrolysis; Kinetics; Lipase; Membrane Potentials; Membranes, Artificial; Models, Biological; Molecular Conformation; Organophosphonates; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylserines; Phospholipases; Protein Binding; Protein Conformation; Time Factors | 1974 |
The influence of triorthocresylphosphate on the distribution of 32P in the body of the rat after the injection of 32P-sarin.
Topics: Animals; Binding Sites; Blood Cell Count; Blood Proteins; Brain Chemistry; Cholinesterase Inhibitors; Cholinesterases; Electrophoresis; Lipase; Organophosphonates; Phosphates; Phosphoric Acids; Phosphorus; Phosphorus Isotopes; Protein Binding; Rats | 1969 |
Phosphonate analogues of triacylglycerols are potent inhibitors of lipase.
Topics: Carboxylic Ester Hydrolases; Enzyme Inhibitors; Fusarium; Kinetics; Lipase; Organophosphonates; Staphylococcus; Structure-Activity Relationship; Triglycerides | 1995 |
The 2.46 A resolution structure of the pancreatic lipase-colipase complex inhibited by a C11 alkyl phosphonate.
Topics: Binding Sites; Coenzymes; Crystallography, X-Ray; Humans; In Vitro Techniques; Lipase; Models, Molecular; Molecular Structure; Organophosphonates; Pancreas; Protein Conformation; Protein Structure, Tertiary; Substrate Specificity; Triglycerides; Water | 1995 |
Crystallographic and molecular-modeling studies of lipase B from Candida antarctica reveal a stereospecificity pocket for secondary alcohols.
Topics: Alcohols; Binding Sites; Candida; Crystallography, X-Ray; Enzyme Inhibitors; Lipase; Models, Molecular; Organophosphonates; Polysorbates; Protein Conformation; Stereoisomerism; Substrate Specificity; Thermodynamics | 1995 |
Inhibition of microbial lipases with stereoisomeric triradylglycerol analog phosphonates.
Topics: Chromatography, High Pressure Liquid; Chromobacterium; Diglycerides; Enzyme Inhibitors; Glycerol; Kinetics; Lipase; Molecular Conformation; Nitrophenols; Organophosphonates; Rhizopus; Stereoisomerism | 1996 |
Crystal structure of human gastric lipase and model of lysosomal acid lipase, two lipolytic enzymes of medical interest.
Topics: Amino Acid Sequence; Carboxypeptidases; Catalytic Domain; Cathepsin A; Computer Simulation; Crystallography, X-Ray; Humans; Lipase; Lipolysis; Lysosomes; Models, Molecular; Molecular Sequence Data; Organophosphonates; Recombinant Proteins; Sequence Homology, Amino Acid; Stomach | 1999 |
Inhibition of human gastric and pancreatic lipases by chiral alkylphosphonates. A kinetic study with 1,2-didecanoyl-sn-glycerol monolayer.
Topics: Chromatography, High Pressure Liquid; Diglycerides; Enzyme Inhibitors; Humans; In Vitro Techniques; Kinetics; Lipase; Magnetic Resonance Spectroscopy; Organophosphonates; Pancreas; Stereoisomerism; Stomach; Structure-Activity Relationship | 1999 |
Dynamics of the substrate binding pocket in the presence of an inhibitor covalently attached to a fungal lipase.
Topics: Catalytic Domain; Computer Simulation; Enzyme Inhibitors; Lipase; Models, Molecular; Organophosphonates; Protein Conformation; Rhizomucor; Static Electricity; Thermodynamics | 2001 |
Crystal structure of the open form of dog gastric lipase in complex with a phosphonate inhibitor.
Topics: Animals; Crystallography, X-Ray; Dogs; Enzyme Inhibitors; Lipase; Models, Molecular; Organophosphonates; Protein Structure, Secondary; Recombinant Proteins; Spectrometry, Fluorescence; Stomach | 2002 |
Fluorescent inhibitors reveal solvent-dependent micropolarity in the lipid binding sites of lipases.
Topics: 2-Naphthylamine; Binding Sites; Burkholderia cepacia; Enzyme Inhibitors; Fluorescent Dyes; Lipase; Lipids; Molecular Structure; Naphthalenes; Nitrophenols; Organophosphonates; Protein Conformation; Rhizopus; Serine; Solvents; Spectrometry, Fluorescence | 2002 |
Binding of phage displayed Bacillus subtilis lipase A to a phosphonate suicide inhibitor.
Topics: Bacillus Phages; Bacillus subtilis; Bacteriophage M13; Cells, Cultured; Cloning, Molecular; Enzyme Inhibitors; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Isomerism; Lipase; Organophosphonates; Peptide Library; Protein Binding; Protein Engineering; Recombinant Fusion Proteins; Substrate Specificity | 2003 |
Fluorescent organophosphonates as inhibitors of microbial lipases.
Topics: 4-Chloro-7-nitrobenzofurazan; Bacteria; Chromatography, Thin Layer; Enzyme Inhibitors; Fluorescent Dyes; Lipase; Molecular Structure; Nitrophenols; Organophosphonates; Organophosphorus Compounds; Perylene; Pseudomonas; Rhizopus; Spectrometry, Mass, Electrospray Ionization; Triglycerides | 2003 |
Inhibition of dog and human gastric lipases by enantiomeric phosphonate inhibitors: a structure-activity study.
Topics: Animals; Binding Sites; Binding, Competitive; Computer Simulation; Crystallization; Crystallography, X-Ray; Dogs; Enzyme Inhibitors; Humans; Lipase; Models, Molecular; Organophosphonates; Protein Binding; Stereoisomerism; Stomach; Structure-Activity Relationship; Triglycerides | 2003 |
Novel fluorescent phosphonic acid esters for discrimination of lipases and esterases.
Topics: Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Esterases; Fluorescent Dyes; Lipase; Organophosphonates; Oxadiazoles | 2005 |
Overactive endocannabinoid signaling impairs apolipoprotein E-mediated clearance of triglyceride-rich lipoproteins.
Topics: Animals; Apolipoproteins E; Arachidonic Acids; Cannabinoid Receptor Modulators; Cholesterol; Endocannabinoids; Enzyme Inhibitors; Gene Expression Regulation; Glycerides; Lipase; Lipid Metabolism; Lipids; Lipoproteins; Liver; Male; Mice; Organophosphonates; Receptor, Cannabinoid, CB1; Signal Transduction; Triglycerides | 2008 |
Activity based subcellular resolution imaging of lipases.
Topics: Alkynes; Animals; Azides; Catalysis; Chlorocebus aethiops; Click Chemistry; Copper; COS Cells; Lipase; Lipid Metabolism; Microscopy, Fluorescence; Organophosphonates; Proteome | 2012 |
Global profiling of dynamic protein palmitoylation.
Topics: Animals; Cysteine; Fatty Acids, Unsaturated; Lipase; Lipoylation; Mass Spectrometry; Mice; Organophosphonates; Palmitic Acid; Protein Processing, Post-Translational; Serine Endopeptidases; Thiolester Hydrolases | 2011 |
Inhibition of phospholipase A1, lipase and galactolipase activities of pancreatic lipase-related protein 2 by methyl arachidonyl fluorophosphonate (MAFP).
Topics: Arachidonic Acids; Carboxylic Ester Hydrolases; Enzyme Inhibitors; Humans; Lipase; Lipolysis; Organophosphonates; Phospholipases A1; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2012 |
Synthesis and kinetic evaluation of cyclophostin and cyclipostins phosphonate analogs as selective and potent inhibitors of microbial lipases.
Topics: Carboxylic Ester Hydrolases; Enzyme Inhibitors; Fusarium; Kinetics; Lipase; Molecular Structure; Mycobacterium tuberculosis; Organophosphonates; Organophosphorus Compounds; Structure-Activity Relationship | 2012 |
Crystal structure of Proteus mirabilis lipase, a novel lipase from the Proteus/psychrophilic subfamily of lipase family I.1.
Topics: Amino Acid Motifs; Amino Acid Sequence; Bacterial Proteins; Biocatalysis; Calcium; Catalytic Domain; Crystallography, X-Ray; Enzyme Inhibitors; Hydrogen Bonding; Lipase; Models, Molecular; Molecular Sequence Data; Organophosphonates; Protein Structure, Secondary; Proteus mirabilis; Sequence Homology, Amino Acid; Solvents; Water | 2012 |
Enantioselective inhibition of microbial lipolytic enzymes by nonracemic monocyclic enolphosphonate analogues of cyclophostin.
Topics: Bacterial Proteins; Carboxylic Ester Hydrolases; Fungal Proteins; Fusarium; Lipase; Lipolysis; Monoacylglycerol Lipases; Mycobacterium tuberculosis; Organophosphonates; Organophosphorus Compounds; Stereoisomerism | 2013 |
Efficient bifunctional catalyst lipase/organophosphonic acid-functionalized silica for biodiesel synthesis by esterification of oleic acid with ethanol.
Topics: Analysis of Variance; Biocatalysis; Biofuels; Biotechnology; Esterification; Ethanol; Lipase; Microscopy, Electron, Scanning; Models, Theoretical; Oleic Acid; Organophosphonates; Silicon Dioxide; Spectroscopy, Fourier Transform Infrared | 2013 |
Endothelial lipase is a critical determinant of high-density lipoprotein-stimulated sphingosine 1-phosphate-dependent signaling in vascular endothelium.
Topics: Anilides; Animals; Cell Movement; Cell Proliferation; Cells, Cultured; Cholesterol; Endothelium, Vascular; Lipase; Lipoproteins, HDL; Lysophospholipids; Mice; Mice, Knockout; Neovascularization, Physiologic; Nitric Oxide Synthase Type III; Organophosphonates; Phosphorylation; Proto-Oncogene Proteins c-akt; Receptors, Lysosphingolipid; RNA, Small Interfering; Signal Transduction; Sphingosine | 2013 |
Progesterone and a phospholipase inhibitor increase the endosomal bis(monoacylglycero)phosphate content and block HIV viral particle intercellular transmission.
Topics: Androstenes; Arachidonic Acids; Cell Line; Cell Membrane; Cholesterol; Endosomes; Enzyme Inhibitors; HIV; Humans; Lipase; Lysophospholipids; Macrophages; Monocytes; Monoglycerides; Organophosphonates; Phospholipases; Pinocytosis; Progesterone; Virion; Virus Replication | 2013 |
Quantification analysis of yeast-displayed lipase.
Topics: Cell Surface Display Techniques; Enzyme Inhibitors; Fungal Proteins; Lipase; Organophosphonates; Pichia; Saccharomyces cerevisiae | 2014 |
A Cutinase from Trichoderma reesei with a lid-covered active site and kinetic properties of true lipases.
Topics: Amino Acid Sequence; Binding Sites; Carboxylic Ester Hydrolases; Catalysis; Catalytic Domain; Crystallography, X-Ray; Enzyme Inhibitors; Kinetics; Lipase; Lipolysis; Models, Molecular; Molecular Sequence Data; Organophosphonates; Protein Conformation; Sequence Homology, Amino Acid; Trichoderma | 2014 |
Design, synthesis and evaluation of new chromone-derived aminophosphonates as potential acetylcholinesterase inhibitor.
Topics: Acetylcholinesterase; Antioxidants; Biphenyl Compounds; Butyrylcholinesterase; Cholinesterase Inhibitors; Chromones; DNA; Drug Design; Hydrogen Peroxide; Lipase; Molecular Docking Simulation; Organophosphonates; Picrates | 2021 |
Promiscuous Lipase-Catalyzed Knoevenagel-Phospha-Michael Reaction for the Synthesis of Antimicrobial β-Phosphono Malonates.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Catalysis; Escherichia coli; Lipase; Organophosphonates | 2022 |