org gc 94 has been researched along with mianserin in 3 studies
| Studies (org gc 94) | Trials (org gc 94) | Recent Studies (post-2010) (org gc 94) | Studies (mianserin) | Trials (mianserin) | Recent Studies (post-2010) (mianserin) |
|---|---|---|---|---|---|
| 6 | 1 | 0 | 2,624 | 539 | 488 |
| Protein | Taxonomy | org gc 94 (IC50) | mianserin (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 3E | Homo sapiens (human) | 1.4125 | |
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 0.0012 | |
| 5-hydroxytryptamine receptor 3B | Homo sapiens (human) | 1.4125 | |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | 0.163 | |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | 1.078 | |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | 2.066 | |
| 5-hydroxytryptamine receptor 1A | Homo sapiens (human) | 0.3981 | |
| Muscarinic acetylcholine receptor M5 | Rattus norvegicus (Norway rat) | 1.9 | |
| Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | 0.32 | |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 0.0213 | |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | 1.423 | |
| D(2) dopamine receptor | Homo sapiens (human) | 7.0795 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.38 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 0.026 | |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | 0.0661 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 0.872 | |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.21 | |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | 1.405 | |
| D(1A) dopamine receptor | Homo sapiens (human) | 0.543 | |
| D(4) dopamine receptor | Homo sapiens (human) | 3.3113 | |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | 0.21 | |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.21 | |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | 0.38 | |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 0.163 | |
| 5-hydroxytryptamine receptor 3A | Mus musculus (house mouse) | 1.4125 | |
| Histamine H2 receptor | Homo sapiens (human) | 1.008 | |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | 0.083 | |
| Endothelin-1 receptor | Homo sapiens (human) | 0.1148 | |
| 5-hydroxytryptamine receptor 1D | Homo sapiens (human) | 0.3802 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 0.011 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 0.0043 | |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | 0.872 | |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 2.068 | |
| Sodium-dependent serotonin transporter | Rattus norvegicus (Norway rat) | 2.9 | |
| 5-hydroxytryptamine receptor 7 | Homo sapiens (human) | 0.1148 | |
| Alpha-1A adrenergic receptor | Homo sapiens (human) | 0.4074 | |
| Type-2 angiotensin II receptor | Rattus norvegicus (Norway rat) | 0.21 | |
| Histamine H1 receptor | Homo sapiens (human) | 0.0024 | |
| D(3) dopamine receptor | Homo sapiens (human) | 3.8905 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 0.0073 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.19 | |
| 5-hydroxytryptamine receptor 3A | Homo sapiens (human) | 1.4125 | |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | 0.88 | |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | 0.085 | |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | 3.5481 | |
| 5-hydroxytryptamine receptor 3D | Homo sapiens (human) | 1.4125 | |
| 5-hydroxytryptamine receptor 3C | Homo sapiens (human) | 1.4125 | |
| 5-hydroxytryptamine receptor 3B | Mus musculus (house mouse) | 1.4125 | |
| Transporter | Rattus norvegicus (Norway rat) | 0.022 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kitteringham, NR; Park, BK; Riley, RJ; Roberts, P | 1 |
| Hoekstra, A; Joosten, HF; Waalkens, DH; Yih, TD | 1 |
| Delbressine, LP; Groothuis, GM; Meijer, DK; Sandker, GW; Slooff, MJ; Vos, RM | 1 |
3 other study(ies) available for org gc 94 and mianserin
| Article | Year |
|---|---|
Formation of cytotoxic metabolites from phenytoin, imipramine, desipramine, amitriptyline and mianserin by mouse and human hepatic microsomes.
Topics: 7-Alkoxycoumarin O-Dealkylase; Amitriptyline; Animals; Benzoflavones; beta-Naphthoflavone; Biotransformation; Desipramine; Dibenzoxazepines; Enzyme Induction; Humans; Imipramine; Injections, Intraperitoneal; Male; Mianserin; Mice; Mice, Inbred CBA; Microsomes, Liver; Phenobarbital; Phenytoin | 1990 |
The effects of chlorpromazine, mianserin and Org GC94 on reproductive function in the rat.
Topics: Animals; Chlorpromazine; Dibenzazepines; Dibenzoxazepines; Estrus; Female; Male; Mianserin; Ovulation; Ovum Transport; Pregnancy; Rats; Reproduction; Serotonin Antagonists | 1984 |
Metabolism of three pharmacologically active drugs in isolated human and rat hepatocytes: analysis of interspecies variability and comparison with metabolism in vivo.
Topics: Anabolic Agents; Animals; Antidepressive Agents, Tricyclic; Biotransformation; Cell Survival; Cells, Cultured; Dibenzoxazepines; Humans; Liver; Male; Mianserin; Mirtazapine; Norpregnenes; Rats; Rats, Wistar; Species Specificity | 1994 |