org 31806 has been researched along with mifepristone in 8 studies
| Studies (org 31806) | Trials (org 31806) | Recent Studies (post-2010) (org 31806) | Studies (mifepristone) | Trials (mifepristone) | Recent Studies (post-2010) (mifepristone) |
|---|---|---|---|---|---|
| 8 | 0 | 0 | 6,536 | 595 | 1,758 |
| Protein | Taxonomy | org 31806 (IC50) | mifepristone (IC50) |
|---|---|---|---|
| Glucocorticoid receptor | Canis lupus familiaris (dog) | 0.0264 | |
| Bile salt export pump | Homo sapiens (human) | 2.02 | |
| Estrogen receptor | Homo sapiens (human) | 4.311 | |
| Glucocorticoid receptor | Homo sapiens (human) | 0.0249 | |
| Prostaglandin G/H synthase 1 | Ovis aries (sheep) | 0.0003 | |
| Progesterone receptor | Homo sapiens (human) | 0.1347 | |
| Glucocorticoid receptor | Rattus norvegicus (Norway rat) | 0.774 | |
| Glucocorticoid receptor | Mus musculus (house mouse) | 0.0022 | |
| Glycine receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | 0.0022 | |
| Mineralocorticoid receptor | Homo sapiens (human) | 2.0938 | |
| Cytochrome P450 3A4 | Homo sapiens (human) | 9.5 | |
| Coagulation factor VII | Homo sapiens (human) | 0.0003 | |
| Androgen receptor | Homo sapiens (human) | 0.2988 | |
| Cytochrome P450 2C8 | Homo sapiens (human) | 1.5 | |
| Cytochrome P450 2C9 | Homo sapiens (human) | 4.9 | |
| Steroid 17-alpha-hydroxylase/17,20 lyase | Rattus norvegicus (Norway rat) | 0.0016 | |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Oryctolagus cuniculus (rabbit) | 0.555 | |
| Tissue factor | Homo sapiens (human) | 0.0003 | |
| Androgen receptor | Rattus norvegicus (Norway rat) | 0.0083 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 0.0014 | |
| Glycine receptor subunit beta | Rattus norvegicus (Norway rat) | 0.0022 | |
| Glycine receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | 0.0022 | |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | 0.0078 | |
| Glycine receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | 0.0022 | |
| Substance-P receptor | Cavia porcellus (domestic guinea pig) | 0.0015 | |
| Mu-type opioid receptor | Homo sapiens (human) | 2.457 | |
| Estrogen receptor beta | Homo sapiens (human) | 1.528 | |
| Glucocorticoid receptor | Sus scrofa (pig) | 0.0153 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bhakta, A; Kloosterboer, HJ; Mizutani, T; Moudgil, VK | 1 |
| de Gooyer, ME; Deckers, GH; Dijkema, R; Kloosterboer, HJ; Orlemans, EO; Schoonen, WG | 1 |
| Deckers, GH; Kloosterboer, HJ; Schoonen, WG | 1 |
| Bardin, CW; Dao, B; Koide, SS; Li, XJ; Vanage, G | 1 |
| Koper, JW; Lamberts, SW; Molijn, GJ; Stigter, E; van Uffelen, CJ | 1 |
| Ferin, M; Shanen, D; Xia-Zhang, L; Xiao, E | 1 |
| Dinda, S; Herman, M; Hurd, C; Iwasaki, K; Kloosterboer, HJ; Moudgil, VK; Underwood, B | 1 |
| Gonzalez, D; Sánchez-Criado, JE; Tébar, M | 1 |
8 other study(ies) available for org 31806 and mifepristone
| Article | Year |
|---|---|
Novel antiprogestins Org 31806 and 31710: interaction with mammalian progesterone receptor and DNA binding of antisteroid receptor complexes.
Topics: Animals; Cattle; Chickens; Cytosol; DNA; Estrenes; Female; Furans; Kinetics; Mifepristone; Progesterone; Progestins; Promegestone; Receptors, Progesterone; Species Specificity; Uterus | 1992 |
Pharmacological properties of a new selective antiprogestagen: Org 33628.
Topics: Adrenal Glands; Animals; Cell Line; Estrenes; Female; Furans; Gonanes; Guinea Pigs; Humans; In Vitro Techniques; Mifepristone; Ovulation; Pregnancy; Progestins; Receptors, Cell Surface; Receptors, Progesterone; Structure-Activity Relationship | 1995 |
Pharmacology of two new very selective antiprogestagens: Org 31710 and Org 31806.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Abortifacient Agents, Steroidal; Abortion, Induced; Androgen Antagonists; Animals; Estrenes; Female; Furans; Gonanes; Macaca; Male; Mammary Neoplasms, Experimental; Menstruation-Inducing Agents; Mifepristone; Pregnancy; Progestins; Rats; Receptors, Glucocorticoid; Receptors, Progesterone | 1994 |
Comparative effectiveness of three antiprogestins alone and in combination with anordiol in terminating pregnancy in the rat.
Topics: Abortion, Induced; Administration, Oral; Animals; Cohort Studies; Contraceptives, Postcoital; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Estradiol; Estrenes; Female; Furans; Gonanes; Hormone Antagonists; Male; Mifepristone; Norandrostanes; Pregnancy; Progesterone; Rats; Rats, Sprague-Dawley | 1997 |
Antiprogestins and iatrogenic glucocorticoid resistance.
Topics: Binding, Competitive; Dexamethasone; Drug Resistance; Estrenes; Furans; Glucocorticoids; Gonanes; Hormone Antagonists; Humans; Hydrocortisone; In Vitro Techniques; Lymphocyte Activation; Meningeal Neoplasms; Meningioma; Mifepristone; Progestins; Receptors, Glucocorticoid | 1997 |
Tonic support of luteinizing hormone secretion by adrenal progesterone in the ovariectomized monkey replaced with midfollicular phase levels of estradiol.
Topics: Adrenal Glands; Animals; Dexamethasone; Estradiol; Estrenes; Female; Furans; Glucocorticoids; Hormone Antagonists; Luteinizing Hormone; Macaca mulatta; Mifepristone; Ovariectomy; Progesterone; Time Factors | 1997 |
Characterization of ligand binding, DNA binding and phosphorylation of progesterone receptor by two novel progesterone receptor antagonist ligands.
Topics: Binding, Competitive; Blotting, Western; DNA; Electrophoresis, Polyacrylamide Gel; Estrenes; Furans; Gonanes; Hormone Antagonists; Humans; Ligands; Mifepristone; Phosphorylation; Progesterone Congeners; Promegestone; Receptors, Progesterone; Sodium Dodecyl Sulfate; Tumor Cells, Cultured | 1997 |
Mechanism of the stimulatory action of antisteroid RU486 on follicle-stimulating hormone secretion in the cyclic Rat.
Topics: Animals; Estrenes; Estrus; Female; Follicle Stimulating Hormone; Furans; Gonadotropin-Releasing Hormone; Gonanes; Hormone Antagonists; Luteinizing Hormone; Mifepristone; Pentobarbital; Progesterone; Rats; Rats, Wistar | 1999 |