Compounds > org 31710
Page last updated: 2024-09-05

org 31710 and onapristone

org 31710 has been researched along with onapristone in 5 studies

Compound Research Comparison

Studies
(org 31710)		Trials
(org 31710)		Recent Studies (post-2010)
(org 31710)		Studies
(onapristone)		Trials
(onapristone)		Recent Studies (post-2010) (onapristone)
3836253419

Protein Interaction Comparison

ProteinTaxonomyorg 31710 (IC50)onapristone (IC50)
Glucocorticoid receptorHomo sapiens (human)0.027
Prostaglandin G/H synthase 1Ovis aries (sheep)0.0027
Progesterone receptorHomo sapiens (human)0.0026
Mineralocorticoid receptor Homo sapiens (human)0.47
Androgen receptorHomo sapiens (human)0.269

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (80.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
de Gooyer, ME; Deckers, GH; Dijkema, R; Kloosterboer, HJ; Orlemans, EO; Schoonen, WG1
Deckers, GH; Kloosterboer, HJ; Schoonen, WG1
Koper, JW; Lamberts, SW; Molijn, GJ; Stigter, E; van Uffelen, CJ1
Dinda, S; Herman, M; Hurd, C; Iwasaki, K; Kloosterboer, HJ; Moudgil, VK; Underwood, B1
Bellido, C; de Jong, FH; Sánchez-Criado, JE; Tébar, M1

Other Studies

5 other study(ies) available for org 31710 and onapristone

ArticleYear
Pharmacological properties of a new selective antiprogestagen: Org 33628.
    Annals of the New York Academy of Sciences, 1995, Jun-12, Volume: 761

    Topics: Adrenal Glands; Animals; Cell Line; Estrenes; Female; Furans; Gonanes; Guinea Pigs; Humans; In Vitro Techniques; Mifepristone; Ovulation; Pregnancy; Progestins; Receptors, Cell Surface; Receptors, Progesterone; Structure-Activity Relationship

1995
Pharmacology of two new very selective antiprogestagens: Org 31710 and Org 31806.
    Human reproduction (Oxford, England), 1994, Volume: 9 Suppl 1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Abortifacient Agents, Steroidal; Abortion, Induced; Androgen Antagonists; Animals; Estrenes; Female; Furans; Gonanes; Macaca; Male; Mammary Neoplasms, Experimental; Menstruation-Inducing Agents; Mifepristone; Pregnancy; Progestins; Rats; Receptors, Glucocorticoid; Receptors, Progesterone

1994
Antiprogestins and iatrogenic glucocorticoid resistance.
    Life sciences, 1997, Volume: 60, Issue:9

    Topics: Binding, Competitive; Dexamethasone; Drug Resistance; Estrenes; Furans; Glucocorticoids; Gonanes; Hormone Antagonists; Humans; Hydrocortisone; In Vitro Techniques; Lymphocyte Activation; Meningeal Neoplasms; Meningioma; Mifepristone; Progestins; Receptors, Glucocorticoid

1997
Characterization of ligand binding, DNA binding and phosphorylation of progesterone receptor by two novel progesterone receptor antagonist ligands.
    Molecular and cellular biochemistry, 1997, Volume: 175, Issue:1-2

    Topics: Binding, Competitive; Blotting, Western; DNA; Electrophoresis, Polyacrylamide Gel; Estrenes; Furans; Gonanes; Hormone Antagonists; Humans; Ligands; Mifepristone; Phosphorylation; Progesterone Congeners; Promegestone; Receptors, Progesterone; Sodium Dodecyl Sulfate; Tumor Cells, Cultured

1997
Comparison of the effects of antiprogestins RU38486, ZK98299 and ORG31710 on periovulatory hypophysial, ovarian and adrenal hormone secretion in the rat.
    Journal of endocrinological investigation, 2000, Volume: 23, Issue:3

    Topics: Adrenal Glands; Animals; Corticosterone; Estrenes; Female; Follicle Stimulating Hormone; Furans; Gonanes; Hormone Antagonists; Inhibins; Luteinizing Hormone; Mifepristone; Ovary; Ovulation; Pituitary Gland, Posterior; Progesterone; Rats; Rats, Wistar

2000