Compounds > orantinib
Page last updated: 2024-09-05

orantinib and n-(4(n-((2-amino-4-hydroxy-6-quinazolinyl)methyl)prop-2-ynylamino)benzoyl)-l-glutamic acid

orantinib has been researched along with n-(4(n-((2-amino-4-hydroxy-6-quinazolinyl)methyl)prop-2-ynylamino)benzoyl)-l-glutamic acid in 1 studies

Compound Research Comparison

Studies
(orantinib)		Trials
(orantinib)		Recent Studies (post-2010)
(orantinib)		Studies
(n-(4(n-((2-amino-4-hydroxy-6-quinazolinyl)methyl)prop-2-ynylamino)benzoyl)-l-glutamic acid)		Trials
(n-(4(n-((2-amino-4-hydroxy-6-quinazolinyl)methyl)prop-2-ynylamino)benzoyl)-l-glutamic acid)		Recent Studies (post-2010) (n-(4(n-((2-amino-4-hydroxy-6-quinazolinyl)methyl)prop-2-ynylamino)benzoyl)-l-glutamic acid)
11019362501

Protein Interaction Comparison

ProteinTaxonomyorantinib (IC50)n-(4(n-((2-amino-4-hydroxy-6-quinazolinyl)methyl)prop-2-ynylamino)benzoyl)-l-glutamic acid (IC50)
Thymidylate synthase Escherichia coli0.0552
Dihydrofolate reductaseHomo sapiens (human)2.1867
Dihydrofolate reductaseMus musculus (house mouse)6.8
Dihydrofolate reductaseLacticaseibacillus casei3.274
Thymidylate synthaseLacticaseibacillus casei0.0277
Thymidylate synthaseHomo sapiens (human)0.068
Thymidylate synthaseMus musculus (house mouse)2.3752
Thymidylate synthase Rattus norvegicus (Norway rat)0.36
Bifunctional dihydrofolate reductase-thymidylate synthaseToxoplasma gondii0.2636

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bailey-Downs, LC; Gangjee, A; Ihnat, MA; Kisliuk, RL; Thorpe, JE; Zhao, Y1

Other Studies

1 other study(ies) available for orantinib and n-(4(n-((2-amino-4-hydroxy-6-quinazolinyl)methyl)prop-2-ynylamino)benzoyl)-l-glutamic acid

ArticleYear
Novel tricyclic indeno[2,1-d]pyrimidines with dual antiangiogenic and cytotoxic activities as potent antitumor agents.
    Bioorganic & medicinal chemistry, 2012, Jul-15, Volume: 20, Issue:14

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Chick Embryo; Drug Screening Assays, Antitumor; Humans; Indenes; Melanoma, Experimental; Mice; Pyrimidines; Receptor, Platelet-Derived Growth Factor beta

2012