Page last updated: 2024-09-04

oracine and camptothecin

oracine has been researched along with camptothecin in 2 studies

Compound Research Comparison

Studies
(oracine)
Trials
(oracine)
Recent Studies (post-2010)
(oracine)
Studies
(camptothecin)
Trials
(camptothecin)
Recent Studies (post-2010) (camptothecin)
330413,0022,2295,391

Protein Interaction Comparison

ProteinTaxonomyoracine (IC50)camptothecin (IC50)
Histone deacetylase 3Homo sapiens (human)0.05
Multidrug resistance-associated protein 4Homo sapiens (human)7.4
DNA topoisomerase 1Homo sapiens (human)1.9799
Somatostatin receptor type 1Homo sapiens (human)0.0022
Somatostatin receptor type 2Homo sapiens (human)0.0022
Somatostatin receptor type 4Homo sapiens (human)0.0022
Somatostatin receptor type 3Homo sapiens (human)0.0022
Somatostatin receptor type 5Homo sapiens (human)0.0022
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.97
Histone deacetylase 4Homo sapiens (human)0.05
Histone deacetylase 1Homo sapiens (human)0.05
Histone deacetylase 7Homo sapiens (human)0.05
Histone deacetylase 2Homo sapiens (human)0.05
Polyamine deacetylase HDAC10Homo sapiens (human)0.05
Histone deacetylase 11 Homo sapiens (human)0.05
Histone deacetylase 8Homo sapiens (human)0.05
Histone deacetylase 6Homo sapiens (human)0.05
Histone deacetylase 9Homo sapiens (human)0.05
Histone deacetylase 5Homo sapiens (human)0.05

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Antony, S; Cushman, M; Fort, BC; Kohlhagen, G; Meckley, MR; Morrell, A; Nagarajan, M; Pommier, Y1
Antony, S; Cushman, M; Kohlhagen, G; Morrell, A; Pommier, Y1

Other Studies

2 other study(ies) available for oracine and camptothecin

ArticleYear
Synthesis and anticancer activity of simplified indenoisoquinoline topoisomerase I inhibitors lacking substituents on the aromatic rings.
    Journal of medicinal chemistry, 2004, Nov-04, Volume: 47, Issue:23

    Topics: Antineoplastic Agents; Cell Line, Tumor; DNA; DNA Topoisomerases, Type I; Drug Screening Assays, Antitumor; Electrophoresis, Polyacrylamide Gel; Humans; Indenes; Isoquinolines; Models, Molecular; Topoisomerase I Inhibitors

2004
Synthesis of benz[d]indeno[1,2-b]pyran-5,11-diones: versatile intermediates for the design and synthesis of topoisomerase I inhibitors.
    Bioorganic & medicinal chemistry letters, 2006, Apr-01, Volume: 16, Issue:7

    Topics: Drug Design; Enzyme Inhibitors; Pyrans; Topoisomerase I Inhibitors

2006