Page last updated: 2024-09-05

optalidon and caffeine

optalidon has been researched along with caffeine in 10 studies

*Caffeine: A methylxanthine naturally occurring in some beverages and also used as a pharmacological agent. Caffeine's most notable pharmacological effect is as a central nervous system stimulant, increasing alertness and producing agitation. It also relaxes SMOOTH MUSCLE, stimulates CARDIAC MUSCLE, stimulates DIURESIS, and appears to be useful in the treatment of some types of headache. Several cellular actions of caffeine have been observed, but it is not entirely clear how each contributes to its pharmacological profile. Among the most important are inhibition of cyclic nucleotide PHOSPHODIESTERASES, antagonism of ADENOSINE RECEPTORS, and modulation of intracellular calcium handling. [MeSH]

*Caffeine: A methylxanthine naturally occurring in some beverages and also used as a pharmacological agent. Caffeine's most notable pharmacological effect is as a central nervous system stimulant, increasing alertness and producing agitation. It also relaxes SMOOTH MUSCLE, stimulates CARDIAC MUSCLE, stimulates DIURESIS, and appears to be useful in the treatment of some types of headache. Several cellular actions of caffeine have been observed, but it is not entirely clear how each contributes to its pharmacological profile. Among the most important are inhibition of cyclic nucleotide PHOSPHODIESTERASES, antagonism of ADENOSINE RECEPTORS, and modulation of intracellular calcium handling. [MeSH]

Compound Research Comparison

Studies
(optalidon)
Trials
(optalidon)
Recent Studies (post-2010)
(optalidon)
Studies
(caffeine)
Trials
(caffeine)
Recent Studies (post-2010) (caffeine)
110125,5012,3936,825

Protein Interaction Comparison

ProteinTaxonomyoptalidon (IC50)caffeine (IC50)
AcetylcholinesteraseHomo sapiens (human)7.25

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19905 (50.00)18.7374
1990's3 (30.00)18.2507
2000's1 (10.00)29.6817
2010's0 (0.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Hopen, G; Ly, B; Moen, T1
Gallerani, M; Menozzi, L; Monetti, VC; Montezemolo, A; Tola, MR; Zanotti, C1
Audícana, MT; Garmendia, J; Joral, A; Muõz, D; Navarro, JA; Villas, F; Zubizarreta, J1
Bravo, J; Fernandez, L; Garcia-Abujeta, JL; Jerez, J; Quiñones, D; Rodriguez, F; Sanchez, I1
BONETTI, U1
ROMAGNY, G1
BERKEL, I; SAYRE, JW1
LUTZ, W1
Caldarola, G; Cozzani, E; Parodi, A; Pellicano, R1
Biasucci, G; Capra, ME; Cirronis, M; DePaulis, NG; Locatelli, CA; Vezzoni, GM1

Other Studies

10 other study(ies) available for optalidon and caffeine

ArticleYear
[Agranulocytosis caused by foreign analgesics (Optalidon and Nolotil)].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1979, May-10, Volume: 99, Issue:13

    Topics: Administration, Oral; Agranulocytosis; Aminopyrine; Analgesics; Barbiturates; Butylscopolammonium Bromide; Caffeine; Dipyrone; Drug Combinations; Female; Humans; Middle Aged; Nonprescription Drugs; Pyrazoles; Spain

1979
Barbiturate, analgesic, and caffeine withdrawal.
    The American journal of emergency medicine, 1994, Volume: 12, Issue:5

    Topics: Adult; Aminopyrine; Anti-Inflammatory Agents, Non-Steroidal; Barbiturates; Caffeine; Coma; Drug Combinations; Female; Hallucinations; Humans; Substance Withdrawal Syndrome

1994
Intradermal testing of fixed drug eruption.
    Allergy, 1996, Volume: 51, Issue:12

    Topics: Adult; Aminopyrine; Barbiturates; Caffeine; Drug Combinations; Drug Eruptions; Female; Humans; Intradermal Tests; Male; Middle Aged; Trimethoprim, Sulfamethoxazole Drug Combination

1996
Erroneous diagnosis of idiopathic anaphylaxis.
    Allergy, 1999, Volume: 54, Issue:6

    Topics: Adult; Aminopyrine; Anaphylaxis; Barbiturates; Caffeine; Diagnostic Errors; Drug Combinations; Drug Hypersensitivity; Female; Humans

1999
[Mental disorders caused by analgesic poisoning; description of a case caused by optalidon].
    Rivista sperimentale di freniatria e medicina legale delle alienazioni mentali, 1958, Sep-30, Volume: 82, Issue:3

    Topics: Aminopyrine; Analgesics; Barbiturates; Caffeine; Drug Combinations; Humans; Mental Disorders; Psychoses, Substance-Induced; Psychotic Disorders

1958
[Two stage semeiology of optalidon poisoning; therapeutic results; study based on five personal cases in a pediatric service].
    Journal de medecine de Lyon, 1959, Mar-20, Volume: 40, Issue:941

    Topics: Aminopyrine; Barbiturates; Caffeine; Central Nervous System Agents; Child; Drug Combinations; Humans

1959
OPTALIDON POISONING IN CHILDREN: A STUDY OF TWENTY CASES.
    The Turkish journal of pediatrics, 1964, Volume: 6

    Topics: Aminopyrine; Barbiturates; Caffeine; Child; Drug Combinations; Humans; Infant; Toxicology; Turkey

1964
[Extensive fixed exanthem caused by optalidon].
    Dermatologica, 1951, Volume: 102, Issue:4-6

    Topics: Aminopyrine; Barbiturates; Caffeine; Drug Combinations; Drug Eruptions; Exanthema; Humans

1951
A case of linear immunoglobulin A bullous dermatosis in a patient exposed to sun and an analgesic.
    Clinical therapeutics, 2009, Volume: 31, Issue:9

    Topics: Aminopyrine; Barbiturates; Caffeine; Drug Combinations; Female; Glucocorticoids; Humans; Immunoglobulin A; Middle Aged; Prednisone; Skin Diseases, Vesiculobullous; Sunlight; Ultraviolet Rays

2009
Neonatal abstinence syndrome and intra-uterine growth restriction secondary to maternal antimigraine drug abuse.
    Basic & clinical pharmacology & toxicology, 2021, Volume: 128, Issue:4

    Topics: Aminopyrine; Barbiturates; Caffeine; Drug Combinations; Female; Fetal Growth Retardation; Humans; Infant, Newborn; Male; Maternal Exposure; Neonatal Abstinence Syndrome; Substance-Related Disorders

2021