Compounds > opc 4392
Page last updated: 2024-09-05

opc 4392 and domperidone

opc 4392 has been researched along with domperidone in 2 studies

Compound Research Comparison

Studies
(opc 4392)		Trials
(opc 4392)		Recent Studies (post-2010)
(opc 4392)		Studies
(domperidone)		Trials
(domperidone)		Recent Studies (post-2010) (domperidone)
16101,977275468

Protein Interaction Comparison

ProteinTaxonomyopc 4392 (IC50)domperidone (IC50)
Solute carrier family 22 member 2Homo sapiens (human)7.9
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)1.332
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)2.614
Alpha-2A adrenergic receptorHomo sapiens (human)2.74
D(2) dopamine receptorHomo sapiens (human)0.0026
Alpha-2B adrenergic receptorHomo sapiens (human)2.125
Alpha-2C adrenergic receptorHomo sapiens (human)1.011
Sodium-dependent noradrenaline transporter Homo sapiens (human)2.614
Alpha-1D adrenergic receptorHomo sapiens (human)1.065
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.037
5-hydroxytryptamine receptor 2CHomo sapiens (human)1.332
Sodium-dependent serotonin transporterHomo sapiens (human)3.055
Histamine H1 receptorHomo sapiens (human)1.344
Mu-type opioid receptorHomo sapiens (human)4.218
D(3) dopamine receptorHomo sapiens (human)0.018
Kappa-type opioid receptorHomo sapiens (human)6.994
5-hydroxytryptamine receptor 2BHomo sapiens (human)2.6
D(2) dopamine receptorRattus norvegicus (Norway rat)0.0052
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)0.1447
Multidrug and toxin extrusion protein 1Homo sapiens (human)2.3

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Momiyama, T; Sasa, M; Takaori, S1
Ohno, Y; Sasa, M; Takaori, S1

Other Studies

2 other study(ies) available for opc 4392 and domperidone

ArticleYear
D-2 receptor-mediated inhibition by a substituted quinolinone derivative, 7-[3-(4-(2,3-dimethylphenyl)piperazinyl)propoxy]-2(1H)-quinolinone (OPC-4392), of dopaminergic neurons in the ventral tegmental area.
    Life sciences, 1990, Volume: 47, Issue:9

    Topics: Animals; Benzazepines; Domperidone; Dopamine; Dopamine Agents; Electric Stimulation; Male; Neurons; Nucleus Accumbens; Piperazines; Quinolones; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Tegmentum Mesencephali

1990
Presynaptic inhibition of excitatory input from the substantia nigra to caudate nucleus neurons by a substituted quinolinone derivative, 7-[3-(4-(2,3-dimethylphenyl)piperazinyl)propoxy]-2(1H)-quinolinone (OPC-4392).
    Life sciences, 1988, Volume: 43, Issue:3

    Topics: Action Potentials; Animals; Bromocriptine; Cats; Caudate Nucleus; Domperidone; Dopamine; Electric Stimulation; Neural Pathways; Neurons; Piperazines; Quinolines; Quinolones; Sodium Glutamate; Substantia Nigra

1988