opc 4392 has been researched along with dihydroxyphenylalanine in 2 studies
*Dihydroxyphenylalanine: A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific. [MeSH]
*Dihydroxyphenylalanine: A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific. [MeSH]
| Studies (opc 4392) | Trials (opc 4392) | Recent Studies (post-2010) (opc 4392) | Studies (dihydroxyphenylalanine) | Trials (dihydroxyphenylalanine) | Recent Studies (post-2010) (dihydroxyphenylalanine) |
|---|---|---|---|---|---|
| 16 | 1 | 0 | 8,823 | 322 | 833 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hirata, Y; Kiuchi, K; Minami, M; Nagatsu, T | 1 |
| Hiyama, T; Kikuchi, T; Suzuki, S; Tsutsui, M; Yamada, K; Yasuda, Y | 1 |
2 other study(ies) available for opc 4392 and dihydroxyphenylalanine
| Article | Year |
|---|---|
Effect of 7-(3-[4-(2,3-dimethylphenyl)piperazinyl]propoxy)- 2(1H)-quinolinone (OPC-4392), a newly synthesized agonist for presynaptic dopamine D2 receptor, on tyrosine hydroxylation in rat striatal slices.
Topics: Animals; Corpus Striatum; Dihydroxyphenylalanine; Dose-Response Relationship, Drug; Hydroxylation; In Vitro Techniques; Male; Piperazines; Quinolines; Quinolones; Rats; Receptors, Dopamine; Receptors, Neurotransmitter; Tyrosine 3-Monooxygenase | 1988 |
7-[3-(4-[2,3-Dimethylphenyl]piperazinyl)propoxy]-2(1H)-quinolinone (OPC-4392), a presynaptic dopamine autoreceptor agonist and postsynaptic D2 receptor antagonist.
Topics: Animals; Apomorphine; Brain; Corpus Striatum; Diencephalon; Dihydroxyphenylalanine; Frontal Lobe; Hydroxydopamines; Kainic Acid; Kinetics; Male; Mice; Mice, Inbred ICR; Motor Activity; Oxidopamine; Piperazines; Piperidines; Quinolines; Quinolones; Rats; Rats, Inbred Strains; Receptors, Dopamine; Stereotyped Behavior; Telencephalon | 1988 |