Compounds > opc 3911
Page last updated: 2024-09-03

opc 3911 and rolipram

opc 3911 has been researched along with rolipram in 3 studies

Compound Research Comparison

Studies
(opc 3911)		Trials
(opc 3911)		Recent Studies (post-2010)
(opc 3911)		Studies
(rolipram)		Trials
(rolipram)		Recent Studies (post-2010) (rolipram)
16001,60417401

Protein Interaction Comparison

ProteinTaxonomyopc 3911 (IC50)rolipram (IC50)
cGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)1.2233
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8AHomo sapiens (human)1.2233
Retina-specific copper amine oxidaseHomo sapiens (human)0.0003
cGMP-specific 3',5'-cyclic phosphodiesteraseHomo sapiens (human)1.0975
3',5'-cyclic-AMP phosphodiesterase Sus scrofa (pig)3.63
ReninHomo sapiens (human)3.5
Tumor necrosis factorHomo sapiens (human)0.35
cAMP-specific 3',5'-cyclic phosphodiesterase 4D Rattus norvegicus (Norway rat)0.7287
cAMP-specific 3',5'-cyclic phosphodiesterase 4CRattus norvegicus (Norway rat)0.7287
cAMP-specific 3',5'-cyclic phosphodiesterase 4BRattus norvegicus (Norway rat)0.8447
cAMP-specific 3',5'-cyclic phosphodiesterase 4AHomo sapiens (human)1.1942
Sodium-dependent serotonin transporterRattus norvegicus (Norway rat)0.095
Delta-type opioid receptorMus musculus (house mouse)1.5
Delta-type opioid receptorRattus norvegicus (Norway rat)1.5
cAMP-specific 3',5'-cyclic phosphodiesterase 4ARattus norvegicus (Norway rat)0.7287
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1BHomo sapiens (human)0.835
cAMP-specific 3',5'-cyclic phosphodiesterase 4BHomo sapiens (human)1.1005
cAMP-specific 3',5'-cyclic phosphodiesterase 4CHomo sapiens (human)1.61
cAMP-specific 3',5'-cyclic phosphodiesterase 4DHomo sapiens (human)1.0794
cGMP-inhibited 3',5'-cyclic phosphodiesterase BHomo sapiens (human)0.835
cGMP-inhibited 3',5'-cyclic phosphodiesterase AHomo sapiens (human)2
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11AHomo sapiens (human)0.835
cAMP-specific 3',5'-cyclic phosphodiesterase 7BHomo sapiens (human)0.835
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10AHomo sapiens (human)0.835

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andersson, KE; Degerman, E; Lindgren, S; Manganiello, V; Rascón, A1
Andersson, KE; Lindgren, S1
Arlock, P; Lindgren, S; Mörner, SE1

Other Studies

3 other study(ies) available for opc 3911 and rolipram

ArticleYear
Selective inhibition of cGMP-inhibited and cGMP-noninhibited cyclic nucleotide phosphodiesterases and relaxation of rat aorta.
    Biochemical pharmacology, 1991, Jul-15, Volume: 42, Issue:3

    Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Animals; Aorta; Cyclic AMP; Cyclic GMP; Drug Interactions; Isoenzymes; Milrinone; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Phenylephrine; Pyridones; Pyrrolidinones; Quinolones; Rats; Rolipram; Serotonin; Vasodilator Agents

1991
Effects of selective phosphodiesterase inhibitors on isolated coronary, lung and renal arteries from man and rat.
    Acta physiologica Scandinavica, 1991, Volume: 142, Issue:1

    Topics: Aged; Animals; Coronary Vessels; Female; Humans; In Vitro Techniques; Male; Middle Aged; Milrinone; Phosphodiesterase Inhibitors; Pulmonary Artery; Pyridones; Pyrrolidinones; Quinolones; Rats; Rats, Inbred Strains; Renal Artery; Rolipram; Vasodilation; Vasodilator Agents

1991
The inotropic mechanism of the phosphodiesterase inhibitor OPC 3911 alone and in combination with rolipram, studied in papillary muscles of ferret and guinea-pig and isolated myocytes of guinea-pig ventricular muscle.
    Acta physiologica Scandinavica, 1994, Volume: 150, Issue:3

    Topics: Action Potentials; Animals; Cardiotonic Agents; Electrophysiology; Ferrets; Guinea Pigs; Heart; Heart Ventricles; In Vitro Techniques; Isometric Contraction; Male; Myocardial Contraction; Myocardium; Papillary Muscles; Phosphodiesterase Inhibitors; Pyrrolidinones; Quinolones; Rolipram; Ventricular Function

1994