opc 3911 has been researched along with milrinone in 6 studies
| Studies (opc 3911) | Trials (opc 3911) | Recent Studies (post-2010) (opc 3911) | Studies (milrinone) | Trials (milrinone) | Recent Studies (post-2010) (milrinone) |
|---|---|---|---|---|---|
| 16 | 0 | 0 | 1,605 | 235 | 452 |
| Protein | Taxonomy | opc 3911 (IC50) | milrinone (IC50) |
|---|---|---|---|
| Phosphodiesterase | Bos taurus (cattle) | 1 | |
| cGMP-dependent 3',5'-cyclic phosphodiesterase | Homo sapiens (human) | 0.3 | |
| High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A | Homo sapiens (human) | 0.3 | |
| cGMP-specific 3',5'-cyclic phosphodiesterase | Homo sapiens (human) | 0.52 | |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | 4.7 | |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4A | Homo sapiens (human) | 6 | |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B | Homo sapiens (human) | 6 | |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4C | Homo sapiens (human) | 6 | |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4D | Homo sapiens (human) | 3.15 | |
| cGMP-inhibited 3',5'-cyclic phosphodiesterase B | Homo sapiens (human) | 1.8674 | |
| cGMP-inhibited 3',5'-cyclic phosphodiesterase A | Homo sapiens (human) | 1.8177 | |
| cGMP-specific 3',5'-cyclic phosphodiesterase | Bos taurus (cattle) | 5 | |
| Phosphodiesterase | Sus scrofa (pig) | 0.843 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 4 (66.67) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Andersson, KE; Degerman, E; Lindgren, S; Manganiello, V; Rascón, A | 1 |
| Andersson, KE; Lindgren, S | 2 |
| Andersson, KE; Andersson, TL; Lindgren, SH; Vinge, E | 1 |
| Andersson, KE; Belfrage, P; Degerman, E; Lindgren, S; Manganiello, VC | 1 |
| Guan, Q; Montrose, DC; Quilley, J; Rajagopalan, S; Smith, CJ; Zhao, H | 1 |
6 other study(ies) available for opc 3911 and milrinone
| Article | Year |
|---|---|
Selective inhibition of cGMP-inhibited and cGMP-noninhibited cyclic nucleotide phosphodiesterases and relaxation of rat aorta.
Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Animals; Aorta; Cyclic AMP; Cyclic GMP; Drug Interactions; Isoenzymes; Milrinone; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Phenylephrine; Pyridones; Pyrrolidinones; Quinolones; Rats; Rolipram; Serotonin; Vasodilator Agents | 1991 |
Effects of selective phosphodiesterase inhibitors on isolated coronary, lung and renal arteries from man and rat.
Topics: Aged; Animals; Coronary Vessels; Female; Humans; In Vitro Techniques; Male; Middle Aged; Milrinone; Phosphodiesterase Inhibitors; Pulmonary Artery; Pyridones; Pyrrolidinones; Quinolones; Rats; Rats, Inbred Strains; Renal Artery; Rolipram; Vasodilation; Vasodilator Agents | 1991 |
Comparison of the effects of milrinone and OPC 3911 with those of isoprenaline, forskolin and dibutyryl-cAMP in rat aorta.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta, Thoracic; Bucladesine; Calcium; Colforsin; In Vitro Techniques; Isoproterenol; Male; Milrinone; Phenylephrine; Phosphodiesterase Inhibitors; Potassium; Pyridones; Quinolones; Rats; Rats, Inbred Strains; Vasodilation | 1991 |
Effects of isozyme-selective phosphodiesterase inhibitors on rat aorta and human platelets: smooth muscle tone, platelet aggregation and cAMP levels.
Topics: Animals; Blood Platelets; Cyclic AMP; Guanfacine; Humans; In Vitro Techniques; Isoenzymes; Isoproterenol; Male; Milrinone; Muscle Tonus; Muscle, Smooth; Muscle, Smooth, Vascular; Phosphodiesterase Inhibitors; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyridones; Quinolones; Rats; Rats, Inbred Strains; Vinca Alkaloids | 1990 |
Relaxant effects of the selective phosphodiesterase inhibitors milrinone and OPC 3911 on isolated human mesenteric vessels.
Topics: Adult; Aged; Calcium Channel Blockers; Colforsin; Female; Humans; In Vitro Techniques; Isoproterenol; Male; Middle Aged; Milrinone; Muscle, Smooth, Vascular; Norepinephrine; Ouabain; Phosphodiesterase Inhibitors; Potassium; Pyridones; Quinolones; Splanchnic Circulation; Vasodilator Agents | 1989 |
Differential effects of phosphodiesterase PDE-3/PDE-4-specific inhibitors on vasoconstriction and cAMP-dependent vasorelaxation following balloon angioplasty.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Angioplasty, Balloon; Animals; Aorta; Carboxylic Acids; Cilostazol; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Male; Milrinone; Nitriles; Phosphodiesterase Inhibitors; Phosphorylation; Quinolones; Rats; Rats, Sprague-Dawley; Tetrazoles; Up-Regulation; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2007 |