opc 3911 has been researched along with carbostyril in 16 studies
| Studies (opc 3911) | Trials (opc 3911) | Recent Studies (post-2010) (opc 3911) | Studies (carbostyril) | Trials (carbostyril) | Recent Studies (post-2010) (carbostyril) |
|---|---|---|---|---|---|
| 16 | 0 | 0 | 12,855 | 1,323 | 5,611 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (6.25) | 18.7374 |
| 1990's | 11 (68.75) | 18.2507 |
| 2000's | 4 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Andersson, KE; Degerman, E; Lindgren, S; Manganiello, V; Rascón, A | 1 |
| Andersson, KE; Lindgren, S | 2 |
| Andersson, TL; Vinge, E | 1 |
| Andersson, KE; Andersson, TL; Lindgren, SH; Vinge, E | 1 |
| Andersson, KE; Belfrage, P; Degerman, E; Lindgren, S; Manganiello, VC | 1 |
| Belfrage, P; Degerman, E; Ekholm, D; Eriksson, H; Manganiello, VC; Ridderstråle, M; Smith, CJ; Tornqvist, H | 1 |
| Arlock, P; Lindgren, S; Mörner, SE | 1 |
| Eriksson, JW; Smith, U; Wesslau, C | 2 |
| Degerman, E; Leroy, MJ; Manganiello, VC; Meacci, E; Movsesian, MA; Murata, T; Taira, M; Wang, LH | 1 |
| Eriksson, H; Tornqvist, H | 1 |
| Abzhalelov, BB; Bronnikov, GE; Dolgacheva, LP; Zhang, SJ; Zinchenko, VP | 1 |
| Degerman, E; Manganiello, V; Oknianska, A; Zmuda-Trzebiatowska, E | 1 |
| Aström, G; Blanc, KL; Dicker, A; Kaaman, M; Rydén, M; van Harmelen, V | 1 |
| Guan, Q; Montrose, DC; Quilley, J; Rajagopalan, S; Smith, CJ; Zhao, H | 1 |
16 other study(ies) available for opc 3911 and carbostyril
| Article | Year |
|---|---|
Selective inhibition of cGMP-inhibited and cGMP-noninhibited cyclic nucleotide phosphodiesterases and relaxation of rat aorta.
Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Animals; Aorta; Cyclic AMP; Cyclic GMP; Drug Interactions; Isoenzymes; Milrinone; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Phenylephrine; Pyridones; Pyrrolidinones; Quinolones; Rats; Rolipram; Serotonin; Vasodilator Agents | 1991 |
Effects of selective phosphodiesterase inhibitors on isolated coronary, lung and renal arteries from man and rat.
Topics: Aged; Animals; Coronary Vessels; Female; Humans; In Vitro Techniques; Male; Middle Aged; Milrinone; Phosphodiesterase Inhibitors; Pulmonary Artery; Pyridones; Pyrrolidinones; Quinolones; Rats; Rats, Inbred Strains; Renal Artery; Rolipram; Vasodilation; Vasodilator Agents | 1991 |
Interactions between isoprenaline, sodium nitroprusside, and isozyme-selective phosphodiesterase inhibitors on ADP-induced aggregation and cyclic nucleotide levels in human platelets.
Topics: Cyclic AMP; Cyclic GMP; Drug Interactions; Humans; Isoproterenol; Nitroprusside; Phosphodiesterase Inhibitors; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinones; Quinolones | 1991 |
Comparison of the effects of milrinone and OPC 3911 with those of isoprenaline, forskolin and dibutyryl-cAMP in rat aorta.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta, Thoracic; Bucladesine; Calcium; Colforsin; In Vitro Techniques; Isoproterenol; Male; Milrinone; Phenylephrine; Phosphodiesterase Inhibitors; Potassium; Pyridones; Quinolones; Rats; Rats, Inbred Strains; Vasodilation | 1991 |
Effects of isozyme-selective phosphodiesterase inhibitors on rat aorta and human platelets: smooth muscle tone, platelet aggregation and cAMP levels.
Topics: Animals; Blood Platelets; Cyclic AMP; Guanfacine; Humans; In Vitro Techniques; Isoenzymes; Isoproterenol; Male; Milrinone; Muscle Tonus; Muscle, Smooth; Muscle, Smooth, Vascular; Phosphodiesterase Inhibitors; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyridones; Quinolones; Rats; Rats, Inbred Strains; Vinca Alkaloids | 1990 |
Relaxant effects of the selective phosphodiesterase inhibitors milrinone and OPC 3911 on isolated human mesenteric vessels.
Topics: Adult; Aged; Calcium Channel Blockers; Colforsin; Female; Humans; In Vitro Techniques; Isoproterenol; Male; Middle Aged; Milrinone; Muscle, Smooth, Vascular; Norepinephrine; Ouabain; Phosphodiesterase Inhibitors; Potassium; Pyridones; Quinolones; Splanchnic Circulation; Vasodilator Agents | 1989 |
Evidence for the key role of the adipocyte cGMP-inhibited cAMP phosphodiesterase in the antilipolytic action of insulin.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adipocytes; Animals; Cyclic GMP; Insulin; Lipolysis; Male; Phosphodiesterase Inhibitors; Propranolol; Quinolones; Rats; Rats, Sprague-Dawley; Sterol Esterase | 1995 |
The inotropic mechanism of the phosphodiesterase inhibitor OPC 3911 alone and in combination with rolipram, studied in papillary muscles of ferret and guinea-pig and isolated myocytes of guinea-pig ventricular muscle.
Topics: Action Potentials; Animals; Cardiotonic Agents; Electrophysiology; Ferrets; Guinea Pigs; Heart; Heart Ventricles; In Vitro Techniques; Isometric Contraction; Male; Myocardial Contraction; Myocardium; Papillary Muscles; Phosphodiesterase Inhibitors; Pyrrolidinones; Quinolones; Rolipram; Ventricular Function | 1994 |
Cellular cyclic AMP levels modulate insulin sensitivity and responsiveness--evidence against a significant role of Gi in insulin signal transduction.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adipocytes; Animals; Cyclic AMP; Epididymis; GTP-Binding Proteins; Insulin; Lipolysis; Male; Pertussis Toxin; Phosphodiesterase Inhibitors; Quinolones; Rats; Rats, Sprague-Dawley; Signal Transduction; Virulence Factors, Bordetella | 1993 |
The cGMP-inhibitable phosphodiesterase modulates glucose transport activation by insulin.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adipocytes; Age Factors; Animals; Biological Transport; Cyclic AMP; Glucose; Insulin; Male; Phosphodiesterase Inhibitors; Quinolones; Rats; Rats, Sprague-Dawley | 1994 |
Characterization of two recombinant PDE3 (cGMP-inhibited cyclic nucleotide phosphodiesterase) isoforms, RcGIP1 and HcGIP2, expressed in NIH 3006 murine fibroblasts and Sf9 insect cells.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adipocytes; Animals; Base Sequence; Cell Line; Chromatography, Gel; Chromatography, Ion Exchange; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 3; DNA Primers; DNA, Complementary; Fibroblasts; Gene Library; Humans; Isoenzymes; Kinetics; Macromolecular Substances; Mice; Molecular Sequence Data; Phosphodiesterase Inhibitors; Polymerase Chain Reaction; Quinolones; Rats; Recombinant Proteins; Spodoptera; Transfection | 1996 |
Specific inhibition of the cGMP-inhibited cAMP phosphodiesterase blocks the insulin-like antilipolytic effect of growth hormone in rat adipocytes.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adipocytes; Animals; Cyclic Nucleotide Phosphodiesterases, Type 3; Growth Hormone; Lipolysis; Quinolones; Rats; Rats, Sprague-Dawley | 1997 |
Norepinephrine induces slow calcium signalling in murine brown preadipocytes through the beta-adrenoceptor/cAMP/protein kinase A pathway.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adipocytes; Adipose Tissue, Brown; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Calcium Signaling; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Isoproterenol; Isoquinolines; Male; Mice; Mice, Inbred Strains; Norepinephrine; Phosphodiesterase Inhibitors; Quinolones; Receptors, Adrenergic, beta; Sulfonamides; Thapsigargin | 2003 |
Role of PDE3B in insulin-induced glucose uptake, GLUT-4 translocation and lipogenesis in primary rat adipocytes.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adipocytes; Animals; Blotting, Western; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 4; Dioxoles; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Glucose; Glucose Transporter Type 4; Guanine Nucleotide Exchange Factors; Insulin; Isoquinolines; Lipogenesis; Male; Quinolones; Rats; Rats, Sprague-Dawley; Signal Transduction; Sulfonamides | 2006 |
Differential function of the alpha2A-adrenoceptor and Phosphodiesterase-3B in human adipocytes of different origin.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 8-Bromo Cyclic Adenosine Monophosphate; Adipocytes; Adult; Blotting, Western; Cell Differentiation; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 3; Female; Humans; Lipolysis; Mesenchymal Stem Cells; Middle Aged; Polymerase Chain Reaction; Quinolones; Receptors, Adrenergic, alpha-2; RNA, Messenger; Yohimbine | 2005 |
Differential effects of phosphodiesterase PDE-3/PDE-4-specific inhibitors on vasoconstriction and cAMP-dependent vasorelaxation following balloon angioplasty.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Angioplasty, Balloon; Animals; Aorta; Carboxylic Acids; Cilostazol; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Male; Milrinone; Nitriles; Phosphodiesterase Inhibitors; Phosphorylation; Quinolones; Rats; Rats, Sprague-Dawley; Tetrazoles; Up-Regulation; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2007 |