opc 28326 has been researched along with piperidines in 9 studies
| Studies (opc 28326) | Trials (opc 28326) | Recent Studies (post-2010) (opc 28326) | Studies (piperidines) | Trials (piperidines) | Recent Studies (post-2010) (piperidines) |
|---|---|---|---|---|---|
| 9 | 1 | 1 | 40,235 | 5,221 | 14,545 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 7 (77.78) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fujiki, H; Imaizumi, T; Kambayashi, J; Kimura, Y; Kishi, M; Mori, T; Orito, K; Shimizu, H; Tanaka, M; Teramoto, S; Tominaga, M; Yoshida, K | 1 |
| Chen, R; Kambayashi, JI; Li, J; Lockyer, S; Sun, B; Yoshitake, M | 1 |
| Hashimoto, A; Imaizumi, T; Kambe, T; Kishi, M; Mori, T; Nakazawa, T; Orito, K | 1 |
| Fujiki, H; Imaizumi, T; Kishi, M; Mori, T; Orito, K; Yoshida, K | 1 |
| Robins, P | 1 |
| Czerwiec, FS; Kambayashi, J; Krasa, H; Leatherman, G; Orlandi, C; White, B; Wigley, FM; Wise, RA; Zhong, J | 1 |
| Chiba, S; Fukui, D; Yang, XP | 1 |
| Hashimoto, A; Imaizumi, T; Mori, T; Nagai, R; Ohki, T; Sata, M; Sumi, M; Yanaga, K | 1 |
| Fujiwara, H; Fujiwara, T; Goto, K; Hashimoto, A; Kanamori, H; Kawasaki, M; Minatoguchi, S; Miyakoda, G; Nagashima, K; Nakagawa, M; Ogino, A; Okada, H; Takemura, G; Tsujimoto, A; Yabuuchi, Y | 1 |
1 trial(s) available for opc 28326 and piperidines
| Article | Year |
|---|---|
Efficacy and tolerability of a selective alpha(2C)-adrenergic receptor blocker in recovery from cold-induced vasospasm in scleroderma patients: a single-center, double-blind, placebo-controlled, randomized crossover study.
Topics: Administration, Oral; Adolescent; Adrenergic alpha-Antagonists; Adult; Aged; Aged, 80 and over; Aniline Compounds; Cold Temperature; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Female; Fingers; Humans; Male; Middle Aged; Piperidines; Raynaud Disease; Regional Blood Flow; Scleroderma, Systemic; Skin Temperature; Vasodilation | 2004 |
8 other study(ies) available for opc 28326 and piperidines
| Article | Year |
|---|---|
Mechanisms of action of OPC-28326, a selective hindlimb vasodilator.
Topics: Adrenergic Antagonists; Anesthesia; Aniline Compounds; Animals; Blood Pressure; Brimonidine Tartrate; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Female; Femoral Artery; Hemodynamics; Hindlimb; In Vitro Techniques; Male; Perfusion; Phenylephrine; Piperidines; Prazosin; Quinoxalines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Vasodilator Agents; Yohimbine | 1999 |
OPC-28326, a selective femoral vasodilator, is an alpha2C-adrenoceptor-selective antagonist.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Alprostadil; Aniline Compounds; Animals; CHO Cells; Cloning, Molecular; Cricetinae; Femoral Vein; Hindlimb; In Situ Hybridization; In Vitro Techniques; Luciferases; Male; Piperidines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Vasodilator Agents; Yohimbine | 2001 |
alpha(2)-adrenoceptor antagonist properties of OPC-28326, a novel selective peripheral vasodilator.
Topics: Adrenergic alpha-Antagonists; Aniline Compounds; Animals; Azepines; Binding, Competitive; Blood Pressure; Brimonidine Tartrate; Decerebrate State; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Muscle Contraction; Mydriasis; Piperidines; Quinoxalines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Vas Deferens; Vasodilator Agents; Yohimbine | 2001 |
Effect of oral OPC-28326, a selective femoral arterial vasodilator, on hindlimb subcutaneous tissue temperature in conscious dogs under buprenorphine sedation.
Topics: Analgesics, Opioid; Aniline Compounds; Animals; Blood Circulation; Body Temperature; Buprenorphine; Consciousness; Dogs; Femoral Artery; Hindlimb; Male; Piperidines; Rectum; Regional Blood Flow; Thigh; Time Factors; Vasodilation; Vasodilator Agents | 2002 |
Japanese Pharmacological Society--77th Annual Meeting. Part I. 8-10 March 2004, Osaka, Japan.
Topics: Aniline Compounds; Animals; Arthritis, Rheumatoid; Bridged Bicyclo Compounds; Dicarboxylic Acids; Drugs, Investigational; Humans; Japan; Myopia; Pharmacology, Clinical; Piperidines; Receptors, Metabotropic Glutamate; Societies, Medical | 2004 |
Neurogenic double-peaked vasoconstriction of human gastroepiploic artery is mediated by both alpha1- and alpha2-adrenoceptors.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Aged; Aniline Compounds; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Female; Gastroepiploic Artery; Humans; Male; Middle Aged; Norepinephrine; Perfusion; Piperidines; Prazosin; Receptors, Adrenergic, alpha; Time Factors; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents; Yohimbine | 2005 |
OPC-28326, a selective femoral arterial vasodilator, augments ischemia induced angiogenesis.
Topics: Aniline Compounds; Animals; Aorta; Blotting, Western; Cells, Cultured; Dose-Response Relationship, Drug; Endothelial Cells; Endothelium, Vascular; Hindlimb; Humans; In Vitro Techniques; Ischemia; Laser-Doppler Flowmetry; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Neovascularization, Physiologic; Nitric Oxide Synthase Type III; Phosphorylation; Piperidines; Rats; Regional Blood Flow; Vasodilator Agents | 2007 |
OPC-28326, a selective peripheral vasodilator with angiogenic activity, mitigates postinfarction cardiac remodeling.
Topics: Angiogenesis Inducing Agents; Aniline Compounds; Animals; Cell Proliferation; Heart; Ki-67 Antigen; Mice; Myocardial Infarction; Myocardium; Myofibroblasts; Nitric Oxide Synthase Type III; Piperidines; Proto-Oncogene Proteins c-akt; Survival Rate; Vasodilator Agents; Ventricular Dysfunction, Left; Ventricular Remodeling | 2015 |