opc 21268 has been researched along with relcovaptan in 10 studies
| Studies (opc 21268) | Trials (opc 21268) | Recent Studies (post-2010) (opc 21268) | Studies (relcovaptan) | Trials (relcovaptan) | Recent Studies (post-2010) (relcovaptan) |
|---|---|---|---|---|---|
| 133 | 3 | 6 | 120 | 9 | 40 |
| Protein | Taxonomy | opc 21268 (IC50) | relcovaptan (IC50) |
|---|---|---|---|
| Vasopressin V1a receptor | Homo sapiens (human) | 0.013 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (90.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Augereau, JM; Bessibes, C; Gleye, J; Granger, I; Rao, RC; Serradeil-Le Gal, C | 1 |
| Berti-Mattera, LN; Dulin, N; Mattera, R; Preston, JA; Thibonnier, M; Wilkins, PL | 1 |
| Kakefuda, A; Sakamoto, S; Suzuki, T; Tahara, A; Tobe, T; Tsukada, J; Tsukamoto, S | 1 |
| Delisee, C; Dol, F; Garcia, C; Herbert, JM; Le Fur, G; Maffrand, JP; Marty, E; Raufaste, D; Schaeffer, P; Serradeil-Le Gal, C | 1 |
| Bourrié, B; Carayon, P; Casellas, P; Garcia, C; Le Fur, G; Maffrand, JP; Raufaste, D; Serradeil-Le Gal, C | 1 |
| Christophe, B; Garcia, C; Guiraudou, P; Lacour, C; Le Fur, G; Maffrand, JP; Nisato, D; Serradeil-Le Gal, C; Villanova, G; Wagnon, J | 1 |
| Bax, WA; Bos, E; Nisato, D; Saxena, PR; Stam, WB; Van der Graaf, PH | 1 |
| Calò, G; Regoli, D; Rizzi, A; Traina, L | 1 |
| Saxena, PR; Stam, WB; Van der Graaf, PH | 1 |
| Ishii, N; Kusayama, T; Saito, M; Sugimoto, T; Tahara, A; Tanaka, A; Tomura, Y; Tsukada, J; Uchida, W; Wada, K; Yatsu, T | 1 |
10 other study(ies) available for opc 21268 and relcovaptan
| Article | Year |
|---|---|
Khusimol, a non-peptide ligand for vasopressin V1a receptors.
Topics: Animals; Arginine Vasopressin; In Vitro Techniques; Ligands; Liver; Magnetic Resonance Spectroscopy; Plants; Polycyclic Sesquiterpenes; Rats; Receptors, Vasopressin; Sesquiterpenes | 1994 |
The human V3 pituitary vasopressin receptor: ligand binding profile and density-dependent signaling pathways.
Topics: Animals; Arachidonic Acid; Base Sequence; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; CHO Cells; Cricetinae; Cyclic AMP; DNA; Dose-Response Relationship, Drug; Female; Humans; Ligands; Pertussis Toxin; Phenotype; Phosphorylation; Pituitary Gland; Protein Binding; Protein Kinase C; Receptors, Vasopressin; Signal Transduction; Thymidine; Tritium; Type C Phospholipases; Virulence Factors, Bordetella | 1997 |
Synthesis and pharmacological evaluation of 5-(4-biphenyl)-3-methyl-4-phenyl-1,2,4-triazole derivatives as a novel class of selective antagonists for the human vasopressin V(1A) receptor.
Topics: Administration, Oral; Animals; Antidiuretic Hormone Receptor Antagonists; Antihypertensive Agents; Blood Pressure; CHO Cells; Cloning, Molecular; Cricetinae; Humans; Injections, Intravenous; Kidney; Liver; Male; Piperazines; Radioligand Assay; Rats; Rats, Wistar; Receptors, Vasopressin; Species Specificity; Structure-Activity Relationship; Triazoles | 2002 |
Effect of SR-49059, a vasopressin V1a antagonist, on human vascular smooth muscle cells.
Topics: Aorta; Arginine Vasopressin; Calcium; Cell Division; Cell Membrane; Cells, Cultured; Deamino Arginine Vasopressin; Dose-Response Relationship, Drug; Humans; Indoles; Iodine Radioisotopes; Kinetics; Muscle, Smooth, Vascular; Oxytocin; Piperidines; Pyrrolidines; Quinolones; Radioligand Assay; Receptors, Vasopressin; Vasopressins | 1995 |
Effect of a new, potent, non-peptide V1a vasopressin antagonist, SR 49059, on the binding and the mitogenic activity of vasopressin on Swiss 3T3 cells.
Topics: 3T3 Cells; Animals; Arginine Vasopressin; Binding Sites; Cell Division; DNA; Flow Cytometry; Indoles; Mice; Mitogens; Piperidines; Pyrrolidines; Quinolones; Receptors, Vasopressin | 1994 |
Biochemical and pharmacological properties of SR 49059, a new, potent, nonpeptide antagonist of rat and human vasopressin V1a receptors.
Topics: Animals; Arginine Vasopressin; Cattle; Cell Membrane; Humans; In Vitro Techniques; Indoles; Muscle Contraction; Piperidines; Platelet Aggregation; Pyrrolidines; Quinolones; Rats; Receptors, Vasopressin | 1993 |
[Arg8]vasopressin-induced responses of the human isolated coronary artery: effects of non-peptide receptor antagonists.
Topics: Adolescent; Adult; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Benzazepines; Child; Coronary Vessels; Endothelium, Vascular; Female; Humans; In Vitro Techniques; Indoles; Male; Middle Aged; Muscle, Smooth, Vascular; Piperidines; Potassium; Pyrrolidines; Quinolones; Vasoconstrictor Agents | 1995 |
Pharmacological characterization of a vasopressin V1 receptor in the isolated human gastric artery.
Topics: Aged; Aged, 80 and over; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Arteries; Benzazepines; Humans; In Vitro Techniques; Indoles; Middle Aged; Muscle, Smooth, Vascular; Oxytocin; Piperidines; Pyrrolidines; Quinolones; Receptors, Vasopressin; Stomach; Vasoconstrictor Agents | 1997 |
Characterization of receptors mediating contraction of the rat isolated small mesenteric artery and aorta to arginine vasopressin and oxytocin.
Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Aorta; Arginine Vasopressin; Dose-Response Relationship, Drug; Hormone Antagonists; In Vitro Techniques; Indoles; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Piperidines; Pyrrolidines; Quinolones; Rats; Rats, Wistar; Receptors, Oxytocin; Receptors, Vasopressin; Vasotocin | 1998 |
Pharmacological characterization of the human vasopressin receptor subtypes stably expressed in Chinese hamster ovary cells.
Topics: Animals; Benzazepines; Binding, Competitive; Calcium; CHO Cells; Cricetinae; Cyclic AMP; Humans; Indoles; Morpholines; Piperidines; Pyrrolidines; Quinolones; Receptors, Vasopressin; Spiro Compounds; Transfection; Tritium | 1998 |