Page last updated: 2024-09-02

opc 21268 and piperidines

opc 21268 has been researched along with piperidines in 118 studies

Compound Research Comparison

Studies (opc 21268)	Trials (opc 21268)	Recent Studies (post-2010) (opc 21268)	Studies (piperidines)	Trials (piperidines)	Recent Studies (post-2010) (piperidines)
133	3	6	40,235	5,221	14,545

Research

Studies (118)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	86 (72.88)	18.2507
2000's	28 (23.73)	29.6817
2010's	4 (3.39)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Hirata, Y; Kohmoto, O; Matsui, H; Serizawa, T	1
Hayashida, W; Kawai, C; Kumada, T	1
Harada, S; Hirooka, Y; Imaizumi, T; Masaki, H; Momohara, M; Takeshita, A	2
Asahina, Y; Fukuma, T; Izumi, N; Liu, JH; Marumo, F; Sakaj, Y; Sato, C; Takano, T; Uchihara, M; Yauchi, T	1
Chiba, S; Tsukada, M	2
Endoh, M; Norota, I; Takanashi, M	1
Chiba, S; Furukawa, Y; Inoue, Y; Ren, LM; Sawaki, S; Takayama, S	1
Hirai, A; Uchida, D; Yoshida, S	1
Ishikawa, S; Okada, K; Saito, T	1
Chihara, T; Kondo, K; Mori, T; Nakamura, S; Ogawa, H; Onogawa, T; Tominaga, M; Yabuuchi, Y; Yamamura, Y	1
Chihara, T; Mori, T; Nakamura, S; Onogawa, T; Tominaga, M; Yabuuchi, Y; Yamamura, Y; Yamashita, T	1
Akishita, M; Etoh, M; Hashimoto, M; Ishikawa, M; Kozaki, K; Liang, J; Nagano, K; Ouchi, Y; Toba, K; Ueda, N	1
Harada, K; Hashimoto, M; Mimura, Y; Ogura, T; Oishi, T; Ota, Z; Otsuka, F; Yamauchi, T	1
Fushimi, K; Hayashi, M; Kitajima, W; Konishi, K; Marumo, F; Monkawa, T; Saruta, T; Sasaki, S; Tsuganezawa, H	1
Abe, K; Hashimoto, J; Imai, Y; Minami, N	1
Aldred, KL; Burrell, LM; Hutchins, AM; Johnston, CI; Phillips, PA; Risvanis, J	1
Kanno, Y; Okada, H; Saruta, T; Suzuki, H	2
Abe, K; Funyu, T; Inoue, M; Kimura, T; Ohta, M; Ota, K; Sato, K; Shoji, M; Yamamoto, T	1
Nakanishi, T; Nanbu, A; Nishimura, M; Sakamoto, M; Takahashi, H; Yoshimura, M	3
Asano, N; Harada, K; Hashimoto, M; Kageyama, J; Mimura, Y; Ogura, T; Oishi, T; Ota, Z; Yamauchi, T	1
Arakawa, K; Ichihara, A; Matsumoto, A; Murakami, M; Naitoh, M; Nakamoto, H; Oka, K; Saruta, T; Suzuki, H; Yamamura, Y	1
Kanno, Y; Okada, H; Saruta, T; Suzuki, H; Yamamura, Y	2
Burrell, LM; Buxton, BF; Johnston, CI; Liu, JJ; Phillips, PA; Rolls, KA	1
Delisee, C; Dol, F; Garcia, C; Herbert, JM; Le Fur, G; Maffrand, JP; Marty, E; Raufaste, D; Schaeffer, P; Serradeil-Le Gal, C	1
Akishita, M; Liang, J; Orimo, H; Ouchi, Y; Toba, K	2
Donald, RA; Ellis, MJ; Evans, MJ; Mulligan, RS	1
Abe, Y; Aki, Y; Fujisawa, Y; Hayashida, Y; Kimura, S; Miyatake, A; Tamaki, T	1
Hoshino, J; Kurashina, T; Murata, K; Nakamura, T; Ono, Z; Sakamaki, T; Sato, K	1
Burrell, LM; Buxton, BB; Johnston, CI; Liu, JJ; Phillips, PA	1
Fujiwara, Y; Nakahama, H; Nakanishi, T; Orita, Y; Sugita, M; Takamitsu, Y; Uyeda, N; Yamada, Y; Yamamura, Y; Yamauchi, A	1
Abe, K; Abe, T; Obinata, M; Takahashi, N; Takeuchi, K; Tsutsumi, E; Yanai, N	1
Ban, Y; Honda, K; Ishiharada, N; Kamiya, H; Saito, R; Takano, Y	1
Bourrié, B; Carayon, P; Casellas, P; Garcia, C; Le Fur, G; Maffrand, JP; Raufaste, D; Serradeil-Le Gal, C	1
Ishikawa, S; Okada, K; Saito, T; Sasaki, R	1
Burrell, LM; Johnston, CI; Phillips, PA; Risvanis, J; Rolls, KA; Stephenson, JM	1
Burrell, LM; Hutchins, AM; Johnston, CI; Phillips, PA; Risvanis, J; Stephenson, J	2
Ichihara, A; Matsumoto, A; Murakami, M; Naitoh, M; Nakamoto, H; Saruta, T; Suzuki, H; Yamamura, Y	1
Crofton, JT; Ota, M; Share, L	1
Chihara, T; Mori, T; Nakamura, S; Onogawa, T; Tominaga, M; Yabuuchi, Y; Yamada, Y; Yamamura, Y; Yamashita, T	1
Kribben, A; Li, X; Nemenoff, RA; Schrier, RW; Tsai, P; Wieder, ED	1
Fujihara, H; Ko, Y; Miyamoto, G; Odomi, M; Ohnishi, A; Okada, K	1
Fujisawa, G; Ishikawa, S; Okada, K; Saito, T; Tsuboi, Y	1
Jamil, KM; Kurokawa, K; Nakao, A; Okuda, T; Watanabe, T	1
Christophe, B; Garcia, C; Guiraudou, P; Lacour, C; Le Fur, G; Maffrand, JP; Nisato, D; Serradeil-Le Gal, C; Villanova, G; Wagnon, J	1
Chihara, T; Kondo, K; Miyamoto, H; Mori, T; Nakaya, K; Ogawa, H; Tominaga, M; Yabuuchi, Y; Yamamura, Y; Yamashita, H	1
Miura, Y; Nakano, H; Nakayama, M; Suzuki, S; Tuchida, H; Yamada, K; Yoshida, S	1
Miura, Y; Nakano, H; Nakayama, M; Suzuki, S; Tsuchida, H; Yamada, K; Yoshida, S	1
Hirai, S; Kosaka, K; Mizuno, K; Nishioka, N; Ohno, S; Osada, S; Suzuki, A	1
Andersen, LF; Atke, A; Barth, T; Hauzerova, L; Vilhardt, H	1
Bax, WA; Bos, E; Nisato, D; Saxena, PR; Stam, WB; Van der Graaf, PH	1
Abe, K; Hashimoto, J; Imai, Y; Minami, N; Munakata, M	1
Abe, Y; Aki, Y; He, H; Kimura, S; Kiyomoto, K; Nishiyama, A; Tamaki, T; Tomohiro, A	1
Kawano, Y; Matsuoka, H; Nishikimi, T; Saito, Y	1
Hanaoka, K; Imai, M; Kurokawa, K; Naruse, M; Yamamura, Y; Yoshitomi, K	1
Abe, K; Hirai, M; Imai, Y; Kurihara, I; Obara, K; Saito, T; Sato, H; Shoji, Y; Soma, J	1
Iizuka, T; Nishikawa, T; Omura, M; Saito, I; Yoshida, S	1
Calò, G; Regoli, D; Rizzi, A; Traina, L	1
Goto, A; Hayakawa, H; Hirata, Y; Hirobe, M; Kakoki, M; Kikuchi, K; Kimura, K; Nagano, T; Nagata, D; Omata, M; Suzuki, E; Tojo, A	1
Aldred, KL; Burrell, LM; Johnston, CI; Naitoh, M; Phillips, PA; Risvanis, J; Rockell, MD	1
Hashimoto, M; Hayakawa, N; Makino, H; Mimura, Y; Ogawa, N; Ogura, T; Otsuka, F; Yamauchi, T	1
Kawano, Y; Matsuoka, H; Nishikimi, T; Omae, T; Takishita, S	1
Bemana, I; Kuyama, H; Nagao, S; Nakamura, T; Takahashi, E	1
Bie, P; Christensen, P; Grove, L	1
Hashimoto, M; Makino, H; Mimura, Y; Ogura, T; Oishi, T; Otsuka, F; Yamauchi, T	1
Ishii, N; Kusayama, T; Tahara, A; Tanaka, A; Tomura, Y; Tsukada, J; Uchida, W; Wada, K; Yatsu, T	1
He, G; Intengan, HD; Schiffrin, EL	1
Charles, CJ; Donald, RA; Ikram, H; Prickett, T; Richards, AM	1
Fujita, H; Iwao, H; Miura, K; Omura, T; Takeuchi, K; Yamagishi, H; Yoshikawa, J; Yoshiyama, M	1
Saxena, PR; Stam, WB; Van der Graaf, PH	1
Daidoh, H; Hanafusa, J; Ishizuka, T; Morita, H; Mune, T; Murase, H; Sato, M; Shibata, T; Suwa, T; Yasuda, K	1
Ishii, N; Kusayama, T; Saito, M; Sugimoto, T; Tahara, A; Tanaka, A; Tomura, Y; Tsukada, J; Uchida, W; Wada, K; Yatsu, T	1
Bemana, I; Nagao, S	1
Burrell, LM; Sampey, DB; Widdop, RE	1
Narimiya, N; Odagiri, M; Ohnishi, A; Sugimoto, I; Tanaka, T	1
Iijima, T; Ishikawa, K; Kurata, S	1
Fukuzawa, J; Haneda, T; Kikuchi, K	1
Abe, Y; Fujisawa, Y; Miyanaka, H; Miyatake, A; Mori, N; Yube, K	1
Fujisawa, S; Iijima, T	1
Hashimoto, K; Hirasawa, A; Inoue, K; Itoh, S; Ohno, Y; Shinoura, H; Take, H; Tsujimoto, G	1
Hotta, H; Ideguchi, S; Suzuki, A; Umino, M	1
Haneda, T; Kikuchi, K; Miyata, S; Nakamura, Y; Osaki, J	1
Ludwig, M; Onaka, T; Yagi, K	1
Coles, P; Conarty, DM; Plesnicher, CL; Shoham, M; Thibonnier, M	1
Ishiguro, S; Iwasaki, T; Miyamoto, A; Mori, T; Nishio, A	1
Burrell, LM; Fraser, TB; Li, M; Turner, SW; Wen, C; Whitworth, JA	1
Otsubo, K	1
Japundzic-Zigon, N	1
Ikebe, M; Kohda, Y; Machida, K; Nonoguchi, H; Star, RA; Tashima, Y; Tomita, K	1
Garcia, G; Le Fur, G; Maffrand, JP; Pascal, M; Serradeil-Le Gal, C; Valette, G; Wagnon, J	1
Ferguson, JW; Hayes, PC; Newby, DE; Therapondos, G	1
Arima, H; Hirabayashi, M; Miura, Y; Murase, T; Nagasaki, H; Oiso, Y; Sugimura, Y; Tachikawa, K; Yokoi, H	1
Honda, K; Ikeda, K; Onaka, T; Yamashita, T	1
Brown, CH; Leng, G; Ludwig, M	1
Egashira, N; Fujiwara, M; Fukue, Y; Higashihara, F; Iwasaki, K; Mishima, K; Takano, Y; Tanoue, A; Tsujimoto, G	1
Japundzić-Zigon, N; Jovanović, A; Milutinović, S	1
Chu, CP; Ishida, Y; Kannan, H; Kato, K; Nishimori, T; Nose, H	1
Aukland, K; Roald, AB; Tenstad, O	1
Akamatsu, S; Hirade, K; Ishisaki, A; Kanno, Y; Kato, K; Kozawa, O; Matsuno, H; Nakajima, K; Oiso, Y; Shu, E; Suga, H; Takai, S; Tanabe, K	1
Chu, CP; Jin, QH; Kannan, H; Kato, K; Oiso, Y; Qiu, DL; Yu, NS	1
Ishikawa, SE; Sasaki, M	1
Aoyagi, T; Hiroyama, M; Oikawa, R; Sanbe, A; Takeo, S; Tanoue, A; Wang, S	1
Carlin, RW; Hagedorn, TM; Schultz, BD	1
Cowley, AW; O'Connor, PM	1
Kanashkina, TA; Mordvintsev, D; Natochin, IuV; Shakhmatova, EI	1
Kawago, K; Matsuda, K; Nishio, T; Sano, Y; Uchiyama, M; Yamada, T	1
Hamada, T; Maejima, S; Matsuda, K; Uchiyama, M; Yamada, T	1
Fujimaki-Aoba, K; Hokari, S; Takada, M	1
Karavashkina, TA; Kutina, AV; Natochin, YV; Shakhmatova, EI	1
Higuchi, K; Koshimizu, TA; Masuki, S; Nose, H; Qian, J; Sumiyoshi, E; Tsujimoto, G	1
Akahoshi, Y; Fujiki, H; Ikeda, T; Iwanaga, Y; Miyazaki, S; Morooka, H; Watanabe, H	1

Reviews

6 review(s) available for opc 21268 and piperidines

Article	Year
[New oral drugs for the treatment of congestive heart failure]. Nihon rinsho. Japanese journal of clinical medicine, 1992, Volume: 50, Issue:2 Topics: Administration, Oral; Cardiotonic Agents; Deoxyepinephrine; Ethanolamines; Heart Failure; Humans; Phosphodiesterase Inhibitors; Piperidines; Propanolamines; Pyrazines; Quinolines; Quinolones; Vasodilator Agents; Xamoterol	1992
[Vasopressin (ADH)]. Nihon rinsho. Japanese journal of clinical medicine, 1992, Volume: 50, Issue:12 Topics: Amino Acid Sequence; Animals; Antidiuretic Hormone Receptor Antagonists; Base Sequence; Blood Pressure; Cloning, Molecular; Cyclic AMP; Humans; Molecular Sequence Data; Piperidines; Quinolones; Receptors, Vasopressin; Vasoconstriction; Vasopressins	1992
[Studies on the efficient syntheses of the drug metabolites]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2000, Volume: 120, Issue:11 Topics: Animals; Anti-Infective Agents; Benzazepines; Chemistry, Organic; Cytochrome P-450 Enzyme System; Fluoroquinolones; Imidazoles; Indans; Lipase; Organic Chemistry Phenomena; Piperazines; Piperidines; Platelet Aggregation Inhibitors; Quinolones; Stereoisomerism; Sulfur Compounds	2000
Nonpeptide vasopressin receptor antagonists: development of selective and orally active V1a, V2 and V1b receptor ligands. Progress in brain research, 2002, Volume: 139 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Humans; Indoles; Ligands; Piperidines; Pyrrolidines; Quinolones; Receptors, Vasopressin; Structure-Activity Relationship	2002
Therapeutic role of vasopressin receptor antagonism in patients with liver cirrhosis. Clinical science (London, England : 1979), 2003, Volume: 105, Issue:1 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Azepines; Benzamides; Benzazepines; Controlled Clinical Trials as Topic; Diuretics; Heart Failure; Homeostasis; Humans; Inappropriate ADH Syndrome; Liver Cirrhosis; Models, Animal; Morpholines; Piperidines; Pyrroles; Quinolones; Rats; Spiro Compounds; Vasopressins	2003
[Renal action of vasopressin]. Nihon rinsho. Japanese journal of clinical medicine, 2006, Volume: 64 Suppl 2 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Aquaporin 2; Arginine Vasopressin; Benzazepines; Diabetes Insipidus; Diabetes Insipidus, Nephrogenic; Drug Design; Humans; Hyponatremia; Inappropriate ADH Syndrome; Mutation; Piperidines; Quinolones; Receptors, Vasopressin	2006

Trials

3 trial(s) available for opc 21268 and piperidines

Article	Year
Pharmacokinetics, safety, and pharmacologic effects of OPC-21268, a nonpeptide orally active vasopressin V1 receptor antagonist, in humans. Journal of clinical pharmacology, 1993, Volume: 33, Issue:3 Topics: Administration, Oral; Adult; Antidiuretic Hormone Receptor Antagonists; Drug Administration Schedule; Humans; Japan; Male; Piperidines; Quinolones; Single-Blind Method; Vasopressins	1993
Short-term clinical trial of 1-(1-[4-(3-acetylaminopropoxy)-benzoyl]-4-piperidyl)-3, 4-dihydro-2(1H)-quinolinone in patients with diabetic nephropathy. Possible effectiveness of the specific vasopressin V1 receptor antagonist for reducing albuminuria in p Arzneimittel-Forschung, 1996, Volume: 46, Issue:9 Topics: Albuminuria; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Blood Glucose; Blood Pressure; Creatinine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Heart Rate; Humans; Male; Middle Aged; Piperidines; Quinolones; Saline Solution, Hypertonic	1996
The role of vasopressin in essential hypertension. Plasma levels and effects of the V1 receptor antagonist OPC-21268 during different dietary sodium intakes. American journal of hypertension, 1997, Volume: 10, Issue:11 Topics: Adult; Aged; Antidiuretic Hormone Receptor Antagonists; Baroreflex; Blood Pressure; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Piperidines; Quinolones; Sodium, Dietary; Vasopressins	1997

Other Studies

109 other study(ies) available for opc 21268 and piperidines

Article	Year
Effects of a nonpeptide vasopressin antagonist (OPC-21268) on cytosolic Ca2+ concentration in vascular and cardiac myocytes. Hypertension (Dallas, Tex. : 1979), 1992, Volume: 19, Issue:6 Pt 2 Topics: Animals; Arginine Vasopressin; Calcium; Cytosol; Muscle, Smooth, Vascular; Myocardium; Osmolar Concentration; Piperidines; Quinolones; Vasopressins	1992
Effects of OPC-21268, an orally effective vasopressin V1 receptor antagonist in humans. Hypertension (Dallas, Tex. : 1979), 1992, Volume: 20, Issue:1 Topics: Administration, Oral; Adult; Angiotensin Receptor Antagonists; Arginine Vasopressin; Dose-Response Relationship, Drug; Forearm; Humans; Injections, Intra-Arterial; Male; Phenylephrine; Piperidines; Quinolones; Receptors, Vasopressin; Regional Blood Flow; Vascular Resistance	1992
V1-receptor mediated GSH efflux by vasopressin from rat hepatocytes. Life sciences, 1992, Volume: 51, Issue:7 Topics: Angiotensin Receptor Antagonists; Animals; Biological Transport; Cells, Cultured; Glutathione; Glycogen; Liver; Male; Piperidines; Quinolones; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Receptors, Vasopressin; Vasopressins	1992
Blocking effects of OPC-21268 and OPC-31260 (vasopressin V1- and V2-receptor antagonists) on vasopressin-induced constrictions in isolated, perfused dog femoral arteries. Japanese journal of pharmacology, 1992, Volume: 59, Issue:1 Topics: Angiotensin Receptor Antagonists; Animals; Benzazepines; Dogs; Dose-Response Relationship, Drug; Femoral Artery; Norepinephrine; Piperidines; Quinolones; Receptors, Vasopressin; Vasoconstriction; Vasopressins	1992
Effects of vasopressin on phosphoinositide hydrolysis and myocardial contractility. European journal of pharmacology, 1992, Aug-06, Volume: 218, Issue:2-3 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Heart Ventricles; Hydrolysis; In Vitro Techniques; Male; Myocardial Contraction; Phosphatidylinositols; Piperidines; Quinolones; Rabbits; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta	1992
Potent antagonistic action of OPC-31260, a vasopressin V2 receptor antagonist, on [Arg8]vasopressin-induced vasoconstriction in isolated simian femoral arteries. European journal of pharmacology, 1992, Oct-20, Volume: 221, Issue:2-3 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Benzazepines; Female; Femoral Artery; In Vitro Techniques; Macaca; Male; Norepinephrine; Piperidines; Quinolones; Vasoconstriction	1992
Blocking effects of V1 (OPC-21268) and V2 (OPC-31260) antagonists on the negative inotropic response to vasopressin in isolated dog heart preparations. The Journal of pharmacology and experimental therapeutics, 1992, Volume: 263, Issue:2 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Benzazepines; Deamino Arginine Vasopressin; Dogs; Heart; Heart Atria; Perfusion; Piperidines; Quinolones; Receptors, Vasopressin	1992
Effect of a new V1 antagonist (OPC-21268) on vascular action of vasopressin in cultured rat vascular smooth muscle cells. Biochemical and biophysical research communications, 1991, Jul-31, Volume: 178, Issue:2 Topics: Angiotensin II; Animals; Aorta, Thoracic; Arginine Vasopressin; Calcium; Cells, Cultured; Kinetics; Male; Muscle, Smooth, Vascular; Piperidines; Quinolones; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Receptors, Vasopressin	1991
OPC-21268, an orally effective, nonpeptide vasopressin V1 receptor antagonist. Science (New York, N.Y.), 1991, Apr-26, Volume: 252, Issue:5005 Topics: Administration, Oral; Angiotensin II; Animals; Arginine Vasopressin; Binding, Competitive; Blood Pressure; Cell Membrane; Kidney; Kinetics; Liver; Norepinephrine; Piperidines; Quinolones; Rats; Receptors, Angiotensin; Receptors, Vasopressin; Time Factors	1991
OPC-21268 antagonizes arginine vasopressin-induced vasoconstrictor response in the spinally-anesthetized dog. Japanese journal of pharmacology, 1995, Volume: 68, Issue:3 Topics: Animals; Arginine Vasopressin; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Injections, Intravenous; Piperidines; Quinolones; Vasoconstriction	1995
Improved skin blood flow and cutaneous temperature in the foot of a patient with arteriosclerosis obliterans by vasopressin V1 antagonist (OPC21268). A case report. Angiology, 1995, Volume: 46, Issue:11 Topics: Aged; Arteriosclerosis Obliterans; Female; Foot; Humans; Piperidines; Quinolones; Radiography; Regional Blood Flow; Skin; Skin Temperature	1995
Effect of vasopressin V1- and V2-receptor stimulation on blood pressure in DOCA-salt hypertensive rats. Acta medica Okayama, 1995, Volume: 49, Issue:4 Topics: Animals; Benzazepines; Blood Pressure; Desoxycorticosterone; Disease Models, Animal; Heart Rate; Male; Piperidines; Quinolones; Rats; Rats, Inbred SHR; Rats, Wistar; Receptors, Vasopressin; Time Factors	1995
Expression and distribution of aquaporin of collecting duct are regulated by vasopressin V2 receptor in rat kidney. The Journal of clinical investigation, 1994, Volume: 94, Issue:5 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Body Water; Immunoblotting; Immunohistochemistry; Ion Channels; Kidney Tubules, Collecting; Male; Permeability; Piperidines; Quinolones; Rats; Rats, Wistar; Receptors, Vasopressin	1994
Contribution of vascular nitric oxide to basal blood pressure in conscious spontaneously hypertensive rats and normotensive Wistar Kyoto rats. Clinical science (London, England : 1979), 1995, Volume: 89, Issue:2 Topics: Animals; Antihypertensive Agents; Arginine; Blood Pressure; Captopril; Endothelium, Vascular; Heart Rate; Hypertension; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pentolinium Tartrate; Piperidines; Quinolones; Rats; Rats, Inbred SHR; Rats, Inbred WKY	1995
Attenuation of genetic hypertension after short-term vasopressin V1A receptor antagonism. Hypertension (Dallas, Tex. : 1979), 1995, Volume: 26, Issue:5 Topics: Aging; Angiotensin-Converting Enzyme Inhibitors; Animals; Antidiuretic Hormone Receptor Antagonists; Blood Pressure; Body Weight; Female; Hypertension; Male; Piperidines; Quinolones; Ramipril; Rats; Rats, Inbred SHR	1995
Effect of nonpeptide vasopressin receptor antagonists on developing, and established DOCA-salt hypertension in rats. Clinical and experimental hypertension (New York, N.Y. : 1993), 1995, Volume: 17, Issue:3 Topics: Administration, Oral; Animals; Antidiuretic Hormone Receptor Antagonists; Benzazepines; Blood Pressure; Body Weight; Desoxycorticosterone; Hypertension; Male; Piperidines; Quinolones; Random Allocation; Rats; Rats, Wistar; Sodium Chloride	1995
Effects of V1- and V2-vasopressin (AVP) antagonists on the pressor, AVP and atrial natriuretic peptide responses to a hypertonic saline infusion in conscious anephric rats. European journal of endocrinology, 1995, Volume: 133, Issue:1 Topics: Animals; Atrial Natriuretic Factor; Benzazepines; Blood Pressure; Heart Rate; Hemodynamics; Kidney; Male; Nephrectomy; Neurons, Afferent; Osmolar Concentration; Piperidines; Plasma Volume; Quinolones; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, Vasopressin; Saline Solution, Hypertonic; Vasopressins	1995
Effects of novel, nonpeptide vasopressin antagonists on progressive nephrosclerosis in rats. Journal of cardiovascular pharmacology, 1995, Volume: 25, Issue:5 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Benzazepines; Biomarkers; Blood Pressure; Body Weight; Disease Models, Animal; Diuresis; Glomerulosclerosis, Focal Segmental; Hypertension; Kidney; Male; Nephrectomy; Nephrosclerosis; Piperidines; Proteinuria; Quinolones; Rats; Rats, Inbred SHR	1995
Cerebral ATP-sensitive potassium channels during acute reduction of carotid blood flow. Hypertension (Dallas, Tex. : 1979), 1995, Volume: 25, Issue:5 Topics: Adenosine Triphosphate; Animals; Arginine Vasopressin; Blood Pressure; Brain; Carotid Arteries; Glyburide; Male; Piperidines; Pituitary Gland; Potassium Channels; Quinolones; Rats; Rats, Wistar; Regional Blood Flow	1995
Enhanced pressor response in spontaneously hypertensive rats induced by stimulation of vasopressin-V1 receptors. Acta medica Okayama, 1995, Volume: 49, Issue:1 Topics: Animals; Arginine Vasopressin; Benzazepines; Blood Pressure; Heart Rate; Hypertension; Male; Piperidines; Quinolones; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Vasopressin; Stimulation, Chemical	1995
Effects of oral AVP receptor antagonists OPC-21268 and OPC-31260 on congestive heart failure in conscious dogs. The American journal of physiology, 1994, Volume: 267, Issue:6 Pt 2 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Benzazepines; Body Weight; Capillary Resistance; Cardiac Output; Cardiac Pacing, Artificial; Diuresis; Dogs; Heart Failure; Hemodynamics; Kidney; Male; Natriuresis; Osmolar Concentration; Piperidines; Potassium; Quinolones; Renin; Sodium	1994
Chronic and selective vasopressin blockade in spontaneously hypertensive rats. The American journal of physiology, 1994, Volume: 267, Issue:6 Pt 2 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Benzazepines; Blood Pressure; Hypertension; Male; Osmolar Concentration; Piperidines; Quinolones; Rats; Rats, Inbred SHR; Rats, Wistar; Receptors, Vasopressin; Urine; Vasopressins	1994
Vascular responses to vasopressin antagonists in man and rat. Clinical science (London, England : 1979), 1994, Volume: 87, Issue:4 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Benzazepines; Culture Techniques; Dose-Response Relationship, Drug; Female; Humans; Mammary Arteries; Mesenteric Artery, Superior; Piperidines; Quinolones; Rats; Rats, Sprague-Dawley; Species Specificity; Vasoconstriction	1994
Effect of SR-49059, a vasopressin V1a antagonist, on human vascular smooth muscle cells. The American journal of physiology, 1995, Volume: 268, Issue:1 Pt 2 Topics: Aorta; Arginine Vasopressin; Calcium; Cell Division; Cell Membrane; Cells, Cultured; Deamino Arginine Vasopressin; Dose-Response Relationship, Drug; Humans; Indoles; Iodine Radioisotopes; Kinetics; Muscle, Smooth, Vascular; Oxytocin; Piperidines; Pyrrolidines; Quinolones; Radioligand Assay; Receptors, Vasopressin; Vasopressins	1995
Effect of an intracerebroventricularly administered vasopressin V1 antagonist on blood pressure and heart rate in deoxycorticosterone-salt hypertensive rats. Journal of the autonomic nervous system, 1994, Dec-15, Volume: 50, Issue:2 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Blood Pressure; Cardiac Output; Desoxycorticosterone; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Injections, Intravenous; Injections, Intraventricular; Male; Microdialysis; Piperidines; Quinolones; Rats; Rats, Wistar	1994
Role of central vasopressin in cardiovascular regulation: effect of dehydration and sex. Gerontology, 1994, Volume: 40 Suppl 2 Topics: Animals; Blood Pressure; Cardiovascular Physiological Phenomena; Cardiovascular System; Dehydration; Female; Heart Rate; Injections, Intraventricular; Male; Piperidines; Quinolones; Rats; Rats, Brattleboro; Sex Factors; Vasopressins	1994
The effects of corticotrophin-releasing hormone, arginine vasopressin and their antagonists on ACTH release from perifused horse anterior pituitary cells. The Journal of endocrinology, 1994, Volume: 143, Issue:1 Topics: Adrenocorticotropic Hormone; Animals; Arginine Vasopressin; Biological Assay; Cells, Cultured; Corticotropin-Releasing Hormone; Dose-Response Relationship, Drug; Drug Synergism; Female; Horses; Male; Piperidines; Pituitary Gland, Anterior; Quinolones	1994
Role of vasopressin on cardiovascular changes during hemorrhage in conscious rats. The American journal of physiology, 1994, Volume: 267, Issue:5 Pt 2 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Benzazepines; Blood Pressure; Heart Rate; Hemorrhage; In Vitro Techniques; Kidney; Male; Piperidines; Quinolones; Rats; Rats, Sprague-Dawley; Renal Artery; Sympathetic Nervous System; Time Factors	1994
Effect of vasopressin V (OPC-21268) and V2 (OPC-31260) antagonists on renal hemodynamics and excretory function. Life sciences, 1994, Volume: 55, Issue:4 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Benzazepines; Blood Pressure; Glomerular Filtration Rate; Kidney; Male; Osmolar Concentration; Piperidines; Quinolones; Rats; Rats, Wistar; Renal Circulation; Urine	1994
Human internal mammary artery responses to non-peptide vasopressin antagonists. Clinical and experimental pharmacology & physiology, 1994, Volume: 21, Issue:2 Topics: Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Arteries; Benzazepines; Breast; Female; Humans; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Piperidines; Quinolones; Receptors, Vasopressin; Regional Blood Flow	1994
Organic osmolytes in rat renal inner medulla are modulated by vasopressin V1 and/or V2 antagonists. The American journal of physiology, 1994, Volume: 267, Issue:1 Pt 2 Topics: Aldehyde Reductase; Animals; Antidiuretic Hormone Receptor Antagonists; Benzazepines; Diuresis; Kidney Medulla; Male; Osmolar Concentration; Osmosis; Piperidines; Quinolones; Rats; Rats, Wistar; RNA, Messenger; Urine; Water Deprivation	1994
Different cellular mechanisms of vasopressin receptor V1 and V2 subtype in vasopressin-induced adenosine 3', 5'-monophosphate formation in an immortalized renal tubule cell line, TKC2. Biochemical and biophysical research communications, 1994, Jul-29, Volume: 202, Issue:2 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Antigens, Polyomavirus Transforming; Benzazepines; Calcium; Cell Line, Transformed; Cyclic AMP; Dinoprostone; Indomethacin; Kidney Tubules; Mice; Mice, Transgenic; Piperidines; Quinolones; Receptors, Vasopressin; Vasopressins	1994
Vasopressin V1 receptor in rat hippocampus is regulated by adrenocortical functions. Brain research, 1994, May-16, Volume: 646, Issue:1 Topics: Adrenal Cortex; Adrenalectomy; Aldosterone; Animals; Arginine Vasopressin; Corticosterone; Dexamethasone; Hippocampus; Male; Piperidines; Quinolones; Rats; Rats, Wistar; Receptors, Vasopressin	1994
Effect of a new, potent, non-peptide V1a vasopressin antagonist, SR 49059, on the binding and the mitogenic activity of vasopressin on Swiss 3T3 cells. Biochemical pharmacology, 1994, Feb-11, Volume: 47, Issue:4 Topics: 3T3 Cells; Animals; Arginine Vasopressin; Binding Sites; Cell Division; DNA; Flow Cytometry; Indoles; Mice; Mitogens; Piperidines; Pyrrolidines; Quinolones; Receptors, Vasopressin	1994
Effects of vasopressin V1 and V2 receptor antagonists on progressive renal failure in rats. Clinical science (London, England : 1979), 1994, Volume: 86, Issue:4 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Benzazepines; Kidney; Kidney Failure, Chronic; Male; Piperidines; Quinolones; Rats; Rats, Wistar; Urine	1994
Distinct inhibition by non-peptide and peptide arginine vasopressin antagonists of vasopressin-induced activation of mitogen-activated protein kinase in cultured rat vascular smooth muscle cells. Biochemical and biophysical research communications, 1994, Apr-29, Volume: 200, Issue:2 Topics: Angiotensin II; Animals; Arginine Vasopressin; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Enzyme Activation; Ionomycin; Muscle, Smooth, Vascular; Piperidines; Quinolones; Rats; Tetradecanoylphorbol Acetate	1994
Blood pressure-lowering effect of an orally active vasopressin V1 receptor antagonist in mineralocorticoid hypertension in the rat. Hypertension (Dallas, Tex. : 1979), 1994, Volume: 23, Issue:6 Pt 1 Topics: Administration, Oral; Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Binding Sites; Blood Pressure; Desoxycorticosterone; Female; Hypertension; Kinetics; Mesenteric Arteries; Piperidines; Quinolones; Rats; Rats, Sprague-Dawley; Receptors, Vasopressin; Sodium Chloride; Systole; Vascular Resistance	1994
Characterization of a novel non-peptide vasopressin V1 receptor antagonist (OPC-21268) in the rat. The Journal of endocrinology, 1993, Volume: 138, Issue:2 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Kidney Medulla; Liver; Piperidines; Protein Binding; Quinolones; Radioligand Assay; Rats; Rats, Sprague-Dawley; Time Factors	1993
Arginine vasopressin produces renal vasodilation via V2 receptors in conscious dogs. The American journal of physiology, 1993, Volume: 265, Issue:4 Pt 2 Topics: Animals; Arginine Vasopressin; Benzazepines; Deamino Arginine Vasopressin; Diuresis; Dogs; Drug Combinations; Hemodynamics; Male; Natriuresis; Osmolar Concentration; Piperidines; Quinolones; Receptors, Vasopressin; Renal Circulation; Vasodilation	1993
Role of vasopressin, the renin-angiotensin system and sex in Dahl salt-sensitive hypertension. Journal of hypertension, 1993, Volume: 11, Issue:10 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Blood Pressure; Captopril; Circadian Rhythm; Diet; Female; Hypertension; Male; Piperidines; Quinolones; Rats; Rats, Mutant Strains; Renin-Angiotensin System; Sex Characteristics; Sodium Chloride; Vasopressins	1993
OPC-21268, a vasopressin V1 antagonist, produces hypotension in spontaneously hypertensive rats. Hypertension (Dallas, Tex. : 1979), 1994, Volume: 23, Issue:2 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Blood Pressure; Hypertension; Male; Piperidines; Quinolones; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley	1994
Inhibition of vasopressin action in vascular smooth muscle by the V1 antagonist OPC-21268. Hypertension (Dallas, Tex. : 1979), 1994, Volume: 23, Issue:2 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Calcium; Cells, Cultured; Male; Mitogen-Activated Protein Kinase 1; Muscle, Smooth, Vascular; Piperidines; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Quinolones; Rats; Rats, Sprague-Dawley	1994
Nonpeptide vasopressin antagonist and its application in the correction of experimental hyponatremia in rats. Regulatory peptides, 1993, Apr-29, Volume: 45, Issue:1-2 Topics: Animals; Benzazepines; Cells, Cultured; Hyponatremia; Inappropriate ADH Syndrome; Kidney Tubules, Collecting; Muscle, Smooth, Vascular; Piperidines; Quinolones; Rats; Rats, Brattleboro; Rats, Sprague-Dawley; Vasopressins	1993
Distinct mechanisms of action of V1 antagonists OPC-21268 and [d(CH2)5Tyr(Me)AVP] in mesangial cells. Biochemical and biophysical research communications, 1993, Jun-15, Volume: 193, Issue:2 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Calcium; Cells, Cultured; Deamino Arginine Vasopressin; Dose-Response Relationship, Drug; Glomerular Mesangium; Kinetics; Piperidines; Quinolones; Rats; Receptors, Vasopressin	1993
Effects of a novel orally effective V1-receptor antagonist, OPC-21268, on AVP-induced sympathoinhibition. The American journal of physiology, 1993, Volume: 264, Issue:6 Pt 2 Topics: Administration, Oral; Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Blood Pressure; Heart Rate; Injections, Intravenous; Kidney; Male; Neural Inhibition; Phenylephrine; Piperidines; Quinolones; Rabbits; Sympathetic Nervous System; Vasopressins	1993
Effects of an orally active vasopressin V1 receptor antagonist. Clinical and experimental pharmacology & physiology, 1993, Volume: 20, Issue:5 Topics: Administration, Oral; Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Binding Sites; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Kidney; Liver; Piperidines; Quinolones; Rats; Rats, Sprague-Dawley; Receptors, Vasopressin	1993
Biochemical and pharmacological properties of SR 49059, a new, potent, nonpeptide antagonist of rat and human vasopressin V1a receptors. The Journal of clinical investigation, 1993, Volume: 92, Issue:1 Topics: Animals; Arginine Vasopressin; Cattle; Cell Membrane; Humans; In Vitro Techniques; Indoles; Muscle Contraction; Piperidines; Platelet Aggregation; Pyrrolidines; Quinolones; Rats; Receptors, Vasopressin	1993
Orally active, nonpeptide vasopressin V1 antagonists. A novel series of 1-(1-substituted 4-piperidyl)-3,4-dihdyro-2(1H)-quinolinone. Journal of medicinal chemistry, 1993, Jul-09, Volume: 36, Issue:14 Topics: Administration, Oral; Animals; Antidiuretic Hormone Receptor Antagonists; Binding Sites; Kidney; Liver; Piperidines; Quinolones; Rats; Structure-Activity Relationship	1993
A lack of anti-hypertensive effect of an orally effective V1 receptor antagonist, OPC-21268, in end-stage renal disease. Clinical nephrology, 1993, Volume: 40, Issue:1 Topics: Adult; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Blood Pressure; Female; Humans; Hypertension, Renal; Kidney Failure, Chronic; Male; Middle Aged; Piperidines; Quinolones	1993
The effect of OPC-21268, an oral, nonpeptide arginine vasopressin V1 receptor antagonist, on a patient with congestive heart failure. Clinical nephrology, 1993, Volume: 40, Issue:1 Topics: Adult; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Blood Pressure; Diabetes Mellitus, Type 2; Female; Heart Failure; Heart Rate; Humans; Kidney Failure, Chronic; Piperidines; Quinolones	1993
Wortmannin inhibits the activation of MAP kinase following vasopressin V1 receptor stimulation. FEBS letters, 1995, Dec-27, Volume: 377, Issue:3 Topics: Androstadienes; Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Benzazepines; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Deamino Arginine Vasopressin; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Fibroblasts; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Piperidines; Quinolones; Rats; Receptors, Vasopressin; Signal Transduction; Tetradecanoylphorbol Acetate; Wortmannin	1995
Effects of the non-peptide inhibitor OPC-21268 on oxytocin and vasopressin stimulation of rat and human myometrium. European journal of pharmacology, 1995, Jul-25, Volume: 281, Issue:1 Topics: Anesthesia; Animals; Antidiuretic Hormone Receptor Antagonists; Cell Membrane; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; In Vitro Techniques; Myometrium; Oxytocin; Piperidines; Pregnancy; Quinolones; Rats; Receptors, Oxytocin; Receptors, Vasopressin; Sensitivity and Specificity; Stimulation, Chemical; Uterine Contraction; Vasopressins	1995
[Arg8]vasopressin-induced responses of the human isolated coronary artery: effects of non-peptide receptor antagonists. European journal of pharmacology, 1995, Oct-16, Volume: 285, Issue:2 Topics: Adolescent; Adult; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Benzazepines; Child; Coronary Vessels; Endothelium, Vascular; Female; Humans; In Vitro Techniques; Indoles; Male; Middle Aged; Muscle, Smooth, Vascular; Piperidines; Potassium; Pyrrolidines; Quinolones; Vasoconstrictor Agents	1995
Effects of vasopressin V1 and V2 receptor antagonists on the development of salt-induced hypertension in Dahl rats. Journal of cardiovascular pharmacology, 1995, Volume: 26, Issue:4 Topics: Analysis of Variance; Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Benzazepines; Blood Pressure; Blood Pressure Determination; Diuresis; Hypertension; Male; Piperidines; Quinolones; Rats; Sodium Chloride	1995
Vasodilation induced by vasopressin V2 receptor stimulation in afferent arterioles. Kidney international, 1996, Volume: 49, Issue:3 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Arterioles; Deamino Arginine Vasopressin; Kidney Glomerulus; Male; Norepinephrine; Perfusion; Piperidines; Quinolones; Rabbits; Receptors, Vasopressin; Renal Agents; Vasoconstrictor Agents; Vasodilation	1996
Effect of long-term treatment with selective vasopressin V1 and V2 receptor antagonist on the development of heart failure in rats. Journal of cardiovascular pharmacology, 1996, Volume: 27, Issue:2 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Benzazepines; Drug Administration Schedule; Heart Failure; Hemodynamics; Male; Organ Size; Piperidines; Quinolones; Random Allocation; Rats; Rats, Wistar	1996
Cerebral adenosine triphosphate-sensitive K+ channels may be impaired during acute cerebral ischemia in spontaneously hypertensive rats. Journal of the autonomic nervous system, 1996, May-06, Volume: 58, Issue:3 Topics: Adenosine Triphosphate; Adrenergic alpha-Antagonists; Animals; Antidiuretic Hormone Receptor Antagonists; Antihypertensive Agents; Arginine Vasopressin; Arterial Occlusive Diseases; Blood Pressure; Brain Ischemia; Carotid Arteries; Cerebral Cortex; Glyburide; Guanidines; Hypertension; Hypoglycemic Agents; Injections, Intravenous; Injections, Intraventricular; Ligation; Male; Pinacidil; Piperidines; Potassium Channels; Quinolones; Rats; Rats, Inbred SHR; Rats, Inbred WKY	1996
Functional characterization of vasopressin V1 and V2 receptors in the rabbit renal cortical collecting duct. Kidney international. Supplement, 1996, Volume: 55 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Benzazepines; Calcium; Cyclic AMP; Electrophysiology; In Vitro Techniques; Kidney Cortex; Kidney Tubules, Collecting; Male; Membrane Potentials; Patch-Clamp Techniques; Piperidines; Quinolones; Rabbits; Receptors, Vasopressin; Renal Agents; Sodium	1996
Effect of a nonpeptide vasopressin V1 antagonist (OPC-21268) on experimental accelerated focal glomerulosclerosis. Nephron, 1996, Volume: 73, Issue:4 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Blood Pressure; Blood Urea Nitrogen; Glomerulosclerosis, Focal Segmental; Hypercholesterolemia; Kidney; Kidney Function Tests; Lipids; Male; Nephrectomy; Piperidines; Proteinuria; Quinolones; Rats; Rats, Inbred Strains	1996
Pharmacological characterization of a vasopressin V1 receptor in the isolated human gastric artery. Life sciences, 1997, Volume: 60, Issue:4-5 Topics: Aged; Aged, 80 and over; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Arteries; Benzazepines; Humans; In Vitro Techniques; Indoles; Middle Aged; Muscle, Smooth, Vascular; Oxytocin; Piperidines; Pyrrolidines; Quinolones; Receptors, Vasopressin; Stomach; Vasoconstrictor Agents	1997
Receptor subtype for vasopressin-induced release of nitric oxide from rat kidney. Hypertension (Dallas, Tex. : 1979), 1997, Volume: 29, Issue:1 Pt 1 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Benzazepines; Desoxycorticosterone; Dinoprost; Dose-Response Relationship, Drug; Enzyme Inhibitors; In Vitro Techniques; Kidney; Male; Nitric Oxide; omega-N-Methylarginine; Perfusion; Piperidines; Quinolones; Rats; Rats, Wistar; Receptors, Vasopressin; Renal Agents	1997
Role of cerebral ATP-sensitive K+ channels in arterial pressure regulation during acute cerebral ischaemia in SHR and WKY rats. Clinical and experimental pharmacology & physiology. Supplement, 1995, Volume: 22, Issue:1 Topics: Adenosine Triphosphate; Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Blood Pressure; Brain Chemistry; Brain Ischemia; Glyburide; Hypoglycemic Agents; Injections, Intraventricular; Male; Piperidines; Pituitary Gland; Potassium Channels; Quinolones; Rats; Rats, Inbred SHR; Rats, Inbred WKY	1995
Modulation of genetic hypertension by short-term AVP V1A or V2 receptor antagonism in young SHR. The American journal of physiology, 1997, Volume: 272, Issue:2 Pt 2 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Benzazepines; Blood Pressure; Hypertension; Male; Myocardium; Organ Size; Piperidines; Quinolones; Ramipril; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Systole; Time Factors	1997
In vitro macro- and microautoradiographic localization of V1 and V2 receptors in the rat kidney using OPC-21268 and OPC-31260. Nephron, 1997, Volume: 76, Issue:3 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Autoradiography; Benzazepines; In Vitro Techniques; Kidney; Ligands; Male; Piperidines; Quinolones; Rats; Rats, Wistar; Receptors, Vasopressin; Tissue Distribution; Tritium; Vasopressins	1997
OPC-21268, an orally effective, nonpeptide arginine vasopressin V1 receptor antagonist reduces vasogenic brain edema. Acta neurochirurgica. Supplement, 1997, Volume: 70 Topics: Administration, Oral; Animals; Antidiuretic Hormone Receptor Antagonists; Blood-Brain Barrier; Brain Edema; Cold Temperature; Male; Piperidines; Quinolones; Rats; Rats, Sprague-Dawley	1997
Effects of receptor blockade on metabolism and renal actions of vasopressin in conscious dogs. Acta physiologica Scandinavica, 1998, Volume: 163, Issue:1 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Benzazepines; Dimethyl Sulfoxide; Dogs; Female; Glomerular Filtration Rate; Hemodynamics; Hormones; Kidney; Natriuresis; Piperidines; Quinolones; Solvents; Vasopressins	1998
Effects of OPC-21268, a vasopressin V1-receptor antagonist, on expression of growth factors from glomeruli in spontaneously hypertensive rats. Regulatory peptides, 1997, Oct-31, Volume: 72, Issue:2-3 Topics: Acetylglucosaminidase; Animals; Antidiuretic Hormone Receptor Antagonists; Blood Pressure; Body Weight; Growth Substances; Heart Rate; Hypertension; Kidney Glomerulus; Organ Size; Piperidines; Platelet-Derived Growth Factor; Polymerase Chain Reaction; Proliferating Cell Nuclear Antigen; Proteinuria; Quinolones; Random Allocation; Rats; Rats, Inbred SHR; RNA, Messenger; Sodium; Transforming Growth Factor beta; Urine	1997
Effect of YM087, a potent nonpeptide vasopressin antagonist, on vasopressin-induced protein synthesis in neonatal rat cardiomyocyte. Cardiovascular research, 1998, Volume: 38, Issue:1 Topics: Analysis of Variance; Animals; Animals, Newborn; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Benzazepines; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Leucine; Myocardium; Piperidines; Protein Biosynthesis; Quinolones; Rats; Rats, Wistar; Receptors, Vasopressin; Stimulation, Chemical; Thymidine	1998
Effect of vasopressin antagonism on structure and mechanics of small arteries and vascular expression of endothelin-1 in deoxycorticosterone acetate salt hypertensive rats. Hypertension (Dallas, Tex. : 1979), 1998, Volume: 32, Issue:4 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Biomechanical Phenomena; Blood Pressure; Desoxycorticosterone; Disease Models, Animal; Elasticity; Endothelin-1; Gene Expression; Hypertension; Male; Mesenteric Artery, Superior; Nephrectomy; Piperidines; Quinolones; Rats; Rats, Sprague-Dawley; Renin; RNA, Messenger; Vasodilation	1998
Arginine vasopressin V1-receptor antagonism in an ovine model of acute myocardial infarction. Journal of cardiovascular pharmacology, 1998, Volume: 32, Issue:5 Topics: Adrenocorticotropic Hormone; Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Corticotropin-Releasing Hormone; Female; Halothane; Hemodynamics; Myocardial Infarction; Piperidines; Quinolones; Renin; Sheep	1998
The effect of vasopressin V1- and V2-receptor antagonists on hemodynamics in early and late phase after myocardial infarction in rats. Japanese journal of pharmacology, 1998, Volume: 78, Issue:2 Topics: Administration, Oral; Animals; Antidiuretic Hormone Receptor Antagonists; Benzazepines; Heart Ventricles; Hemodynamics; Male; Myocardial Infarction; Organ Size; Piperidines; Quinolones; Rats; Rats, Wistar; Time Factors; Vasopressins; Ventricular Function, Left	1998
Characterization of receptors mediating contraction of the rat isolated small mesenteric artery and aorta to arginine vasopressin and oxytocin. British journal of pharmacology, 1998, Volume: 125, Issue:4 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Aorta; Arginine Vasopressin; Dose-Response Relationship, Drug; Hormone Antagonists; In Vitro Techniques; Indoles; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Piperidines; Pyrrolidines; Quinolones; Rats; Rats, Wistar; Receptors, Oxytocin; Receptors, Vasopressin; Vasotocin	1998
In vivo and in vitro effects of AVP and V1a receptor antagonist on Cushing's syndrome due to ACTH-independent bilateral macronodular adrenocortical hyperplasia. Clinical endocrinology, 1998, Volume: 49, Issue:3 Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Cells, Cultured; Cushing Syndrome; Diuretics; Drug Administration Schedule; Furosemide; Gastric Inhibitory Polypeptide; Humans; Hydrocortisone; Hyperplasia; Injections, Intravenous; Insulin; Male; Middle Aged; Piperidines; Posture; Quinolones	1998
Pharmacological characterization of the human vasopressin receptor subtypes stably expressed in Chinese hamster ovary cells. British journal of pharmacology, 1998, Volume: 125, Issue:7 Topics: Animals; Benzazepines; Binding, Competitive; Calcium; CHO Cells; Cricetinae; Cyclic AMP; Humans; Indoles; Morpholines; Piperidines; Pyrrolidines; Quinolones; Receptors, Vasopressin; Spiro Compounds; Transfection; Tritium	1998
Treatment of brain edema with a nonpeptide arginine vasopressin V1 receptor antagonist OPC-21268 in rats. Neurosurgery, 1999, Volume: 44, Issue:1 Topics: Administration, Oral; Animals; Antidiuretic Hormone Receptor Antagonists; Blood-Brain Barrier; Brain Edema; Dose-Response Relationship, Drug; Male; Piperidines; Quinolones; Rats; Rats, Sprague-Dawley; Water-Electrolyte Balance	1999
Vasopressin V2 receptor enhances gain of baroreflex in conscious spontaneously hypertensive rats. The American journal of physiology, 1999, Volume: 276, Issue:3 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Baroreflex; Benzazepines; Blood Pressure; Heart Rate; Injections, Intravenous; Male; Piperidines; Quinolones; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Vasopressin	1999
Protective effect of a vasopressin-1 selective antagonist, OPC-21268, against ethanol-induced damage of the rat gastric wall. Digestive diseases and sciences, 1999, Volume: 44, Issue:3 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Ethanol; Gastric Mucosa; Male; Microcirculation; Piperidines; Quinolones; Rats; Stomach Ulcer; Vasopressins	1999
Enhancement by arginine vasopressin of the L-type Ca2+ current in guinea pig ventricular myocytes. Pharmacology, 1999, Volume: 59, Issue:1 Topics: Animals; Arginine Vasopressin; Calcium; Calcium Channels; Calcium Channels, L-Type; Dose-Response Relationship, Drug; Guinea Pigs; Heart; Isoproterenol; Piperidines; Potassium Channels; Quinolones	1999
Arginine vasopressin increases the rate of protein synthesis in isolated perfused adult rat heart via the V1 receptor. Molecular and cellular biochemistry, 1999, Volume: 195, Issue:1-2 Topics: Amiloride; Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Calcium; Cyclic AMP; In Vitro Techniques; Male; Myocardium; Peptide Biosynthesis; Perfusion; Piperidines; Pressure; Quinolones; Rats; Rats, Sprague-Dawley; Receptors, Vasopressin	1999
Role of nitric oxide in regulation of renal sympathetic nerve activity during hemorrhage in conscious rats. The American journal of physiology, 1999, Volume: 277, Issue:1 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Arginine; Blood Pressure; Consciousness; Enzyme Inhibitors; Heart Rate; Hemorrhage; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Piperidines; Quinolones; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System	1999
On the inotropic actions of arginine vasopressin in ventricular muscle of the guinea pig heart. Japanese journal of pharmacology, 1999, Volume: 81, Issue:3 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Guinea Pigs; Heart Ventricles; In Vitro Techniques; Membrane Potentials; Myocardial Contraction; Piperidines; Quinolones; Staurosporine; Ventricular Function	1999
Key amino acids of vasopressin V1a receptor responsible for the species difference in the affinity of OPC-21268. FEBS letters, 2000, Jan-28, Volume: 466, Issue:2-3 Topics: Amino Acid Sequence; Amino Acids; Animals; Antidiuretic Hormone Receptor Antagonists; Humans; Molecular Sequence Data; Piperidines; Protein Binding; Quinolones; Rats; Receptors, Vasopressin; Recombinant Fusion Proteins; Species Specificity	2000
Trigeminally induced cardiovascular reflex responses in spinalized rats. Journal of the autonomic nervous system, 2000, Mar-15, Volume: 79, Issue:2-3 Topics: Animals; Atropine Derivatives; Blood Pressure; Cardiovascular System; Decerebrate State; Heart Rate; Male; Parasympatholytics; Piperidines; Quinolones; Rats; Rats, Wistar; Reference Values; Reflex; Trigeminal Nerve; Vagotomy	2000
Hypertrophic growth of cultured neonatal rat heart cells mediated by vasopressin V(1A) receptor. European journal of pharmacology, 2000, Mar-10, Volume: 391, Issue:1-2 Topics: Animals; Animals, Newborn; Antidiuretic Hormone Receptor Antagonists; Benzazepines; Blotting, Northern; Calcium; Cardiomegaly; Cells, Cultured; Culture Media; DNA; Kinetics; Myocardium; Piperidines; Protein Biosynthesis; Protein Kinase C; Proteins; Proto-Oncogene Proteins c-fos; Quinolones; Rats; Rats, Sprague-Dawley; Receptors, Vasopressin; RNA, Messenger; Second Messenger Systems; Vasopressins	2000
Vasopressin regulation of noradrenaline release within the supraoptic nucleus. Journal of neuroendocrinology, 2000, Volume: 12, Issue:6 Topics: Antidiuretic Hormone Receptor Antagonists; Chromatography, High Pressure Liquid; Electrochemistry; Neurons; Norepinephrine; Piperidines; Potassium; Quinolones; Supraoptic Nucleus; Vasopressins	2000
A molecular model of agonist and nonpeptide antagonist binding to the human V(1) vascular vasopressin receptor. The Journal of pharmacology and experimental therapeutics, 2000, Volume: 294, Issue:1 Topics: Amino Acid Sequence; Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Humans; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Piperidines; Quinolones; Radioligand Assay; Rats; Receptors, Vasopressin	2000
Vasopressin receptor subtypes on mesenteric and cremasteric arterioles in rat. European journal of pharmacology, 2000, Jul-14, Volume: 400, Issue:1 Topics: Animals; Arginine Vasopressin; Arterioles; Benzazepines; Male; Mesenteric Arteries; Muscle, Skeletal; Piperidines; Quinolones; Rats; Rats, Wistar; Receptors, Vasopressin; Vasoconstriction	2000
Vasopressin V1a receptor antagonism does not reverse adrenocorticotrophin-induced hypertension in the rat. Clinical and experimental pharmacology & physiology, 2000, Volume: 27, Issue:11 Topics: Adrenocorticotropic Hormone; Animals; Antidiuretic Hormone Receptor Antagonists; Blood Pressure; Body Weight; Hematocrit; Hypertension; Male; Organ Size; Osmolar Concentration; Piperidines; Quinolones; Rats; Rats, Sprague-Dawley; Urodynamics	2000
Effects of nonpeptide V1a and V2 antagonists on blood pressure fast oscillations in conscious rats. Clinical and experimental hypertension (New York, N.Y. : 1993), 2001, Volume: 23, Issue:4 Topics: Analysis of Variance; Animals; Antidiuretic Hormone Receptor Antagonists; Benzazepines; Blood Pressure; Heart Rate; Hemorrhage; Hypovolemia; Male; Piperidines; Quinolones; Rats; Receptors, Vasopressin	2001
Intranephron localization and regulation of the V1a vasopressin receptor during chronic metabolic acidosis and dehydration in rats. Pflugers Archiv : European journal of physiology, 2001, Volume: 442, Issue:5 Topics: Acidosis; Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Bicarbonates; Dehydration; Down-Regulation; Homeostasis; Immunohistochemistry; Male; Nephrons; Piperidines; Polymerase Chain Reaction; Quinolones; Rats; Rats, Sprague-Dawley; Receptors, Vasopressin; RNA, Messenger; Up-Regulation; Vacuolar Proton-Translocating ATPases	2001
Altered cardiovascular regulation in arginine vasopressin-overexpressing transgenic rat. American journal of physiology. Endocrinology and metabolism, 2003, Volume: 285, Issue:6 Topics: Adaptation, Physiological; Animals; Animals, Genetically Modified; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Blood Pressure; Carotid Artery Diseases; Hemorrhage; Hemostasis; Male; Piperidines; Quinolones; Rats; Rats, Sprague-Dawley; Receptors, Vasopressin	2003
Facilitative role of endogenous oxytocin in noradrenaline release in the rat supraoptic nucleus. The European journal of neuroscience, 2003, Volume: 18, Issue:11 Topics: Analysis of Variance; Animals; Antidiuretic Hormone Receptor Antagonists; Brain Chemistry; Camphanes; Conditioning, Psychological; Dose-Response Relationship, Drug; Drug Interactions; Electrochemistry; Electroshock; Fear; Male; Microdialysis; Norepinephrine; Oxytocin; Piperazines; Piperidines; Potassium; Quinolones; Radioimmunoassay; Rats; Rats, Wistar; Receptors, Oxytocin; Stimulation, Chemical; Supraoptic Nucleus; Synaptosomes	2003
Temporal dissociation of the feedback effects of dendritically co-released peptides on rhythmogenesis in vasopressin cells. Neuroscience, 2004, Volume: 124, Issue:1 Topics: Action Potentials; Animals; Antidiuretic Hormone Receptor Antagonists; Dendrites; Dynorphins; Feedback, Physiological; Female; Naltrexone; Narcotic Antagonists; Periodicity; Piperidines; Quinolones; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Supraoptic Nucleus; Vasopressins	2004
V1a receptor knockout mice exhibit impairment of spatial memory in an eight-arm radial maze. Neuroscience letters, 2004, Feb-19, Volume: 356, Issue:3 Topics: Analysis of Variance; Animals; Antidiuretic Hormone Receptor Antagonists; Choice Behavior; Dose-Response Relationship, Drug; Male; Maze Learning; Memory Disorders; Mice; Mice, Inbred C57BL; Mice, Knockout; Piperidines; Quinolones; Receptors, Vasopressin; Spatial Behavior	2004
Effects of nonpeptide and selective V1 and V2 antagonists on blood pressure short-term variability in spontaneously hypertensive rats. Journal of pharmacological sciences, 2004, Volume: 95, Issue:1 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Benzazepines; Blood Pressure; Hypertension; Male; Piperidines; Quinolones; Rats; Rats, Inbred SHR; Rats, Wistar; Receptors, Vasopressin	2004
Regional differences in the expression of Fos-like immunoreactivity after central salt loading in conscious rats: modulation by endogenous vasopressin and role of the area postrema. Brain research, 2004, Oct-01, Volume: 1022, Issue:1-2 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Area Postrema; Blood Pressure; Cell Count; Consciousness; Dose-Response Relationship, Drug; Gene Expression; Heart Rate; Hypothalamus; Immunohistochemistry; Ion-Selective Electrodes; Male; Piperidines; Proto-Oncogene Proteins c-fos; Quinolones; Rats; Rats, Sprague-Dawley; Saline Solution, Hypertonic; Salts; Sodium; Solitary Nucleus; Time Factors; Vasopressins	2004
The effect of AVP-V receptor stimulation on local GFR in the rat kidney. Acta physiologica Scandinavica, 2004, Volume: 182, Issue:2 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Diuresis; Female; Glomerular Filtration Rate; Kidney; Kidney Cortex; Ornipressin; Piperidines; Quinolones; Rats; Rats, Sprague-Dawley; Receptors, Vasopressin	2004
Possible involvement of phosphatidylinositol 3-kinase/Akt signal pathway in vasopressin-induced HSP27 phosphorylation in aortic smooth muscle A10 cells. Archives of biochemistry and biophysics, 2005, Jun-15, Volume: 438, Issue:2 Topics: Animals; Aorta; Blotting, Western; Cell Line; Chromones; Enzyme Inhibitors; Heat-Shock Proteins; HSP27 Heat-Shock Proteins; Imidazoles; MAP Kinase Signaling System; Molecular Chaperones; Morpholines; Muscle, Smooth; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Neoplasm Proteins; Phosphatidylinositol 3-Kinases; Phosphorylation; Piperidines; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyridines; Quinolones; Rats; Time Factors; Vasopressins	2005
Enhanced cardiovascular alteration and Fos expression induced by central salt loading in a conscious rat transgenic for the metallothionein-vasopressin fusion gene. Neuroscience research, 2005, Volume: 53, Issue:2 Topics: Animals; Animals, Genetically Modified; Antidiuretic Hormone Receptor Antagonists; Arginine; Brain; Cardiovascular System; Consciousness; Immunohistochemistry; Injections, Intraventricular; Male; Metallothionein; Oncogene Proteins v-fos; Piperidines; Quinolones; Rats; Rats, Sprague-Dawley; Receptors, Vasopressin; Recombinant Fusion Proteins; Saline Solution, Hypertonic; Sodium Chloride; Vasopressins	2005
Vasopressin promotes cardiomyocyte hypertrophy via the vasopressin V1A receptor in neonatal mice. European journal of pharmacology, 2007, Mar-22, Volume: 559, Issue:2-3 Topics: Animals; Animals, Newborn; Arginine Vasopressin; Atrial Natriuretic Factor; Cardiomegaly; Cell Enlargement; Cells, Cultured; Disease Models, Animal; DNA; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Immunohistochemistry; Male; Mice; Mice, Knockout; Myocytes, Cardiac; Phosphorylation; Piperidines; Protein Biosynthesis; Quinolones; Receptors, Vasopressin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Transcription, Genetic; Vasoconstrictor Agents	2007
Oxytocin and vasopressin stimulate anion secretion by human and porcine vas deferens epithelia. Biology of reproduction, 2007, Volume: 77, Issue:3 Topics: Alkaloids; Animals; Anions; Antidiuretic Hormone Receptor Antagonists; Benzophenanthridines; Cell Line; Cyclic AMP; Electrophysiology; Epithelial Cells; Humans; Ion Transport; Male; Oxytocin; Piperidines; Quinolones; Receptors, Oxytocin; Receptors, Vasopressin; Reverse Transcriptase Polymerase Chain Reaction; Swine; Vas Deferens; Vasopressins	2007
Vasopressin-induced nitric oxide production in rat inner medullary collecting duct is dependent on V2 receptor activation of the phosphoinositide pathway. American journal of physiology. Renal physiology, 2007, Volume: 293, Issue:2 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Benzazepines; Calcium; Calcium-Transporting ATPases; Cyclic AMP-Dependent Protein Kinases; Kidney Medulla; Kidney Tubules, Collecting; Male; Nitric Oxide; Phosphatidylinositols; Piperidines; Quinolones; Rats; Rats, Sprague-Dawley; Receptors, Vasopressin; Signal Transduction; Spectrometry, Fluorescence; Type C Phospholipases; Vasopressins	2007
[Vasopressin receptors: structure and stimulation by 1-deamino-arginine-vasotocin in rats]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2007, Volume: 93, Issue:6 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Female; Piperidines; Protein Structure, Quaternary; Quinolones; Rats; Rats, Wistar; Receptors, Vasopressin; Sodium; Vasotocin; Water; Water-Electrolyte Balance	2007
Effects of arginine vasotocin and vasopressin receptor antagonists on Na+ and Cl- transport in the isolated skin of two frog species, Hyla japonica and Rana nigromaculata. General and comparative endocrinology, 2008, May-15, Volume: 157, Issue:1 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Anura; Benzazepines; Biological Transport; Chlorides; Colforsin; Dose-Response Relationship, Drug; Electrophysiology; Female; In Vitro Techniques; Male; Piperidines; Quinolones; Receptors, Vasopressin; Skin; Sodium; Species Specificity; Time Factors; Vasotocin	2008
Effects of hypertonic stimuli and arginine vasotocin (AVT) on water absorption response in Japanese treefrog, Hyla japonica. General and comparative endocrinology, 2008, Volume: 157, Issue:2 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Benzazepines; Biological Transport; Central Nervous System; Dose-Response Relationship, Drug; Glucose Solution, Hypertonic; Hypertonic Solutions; Osmotic Pressure; Piperidines; Quinolones; Ranidae; Receptors, Vasopressin; Saline Solution, Hypertonic; Vasotocin; Water; Water-Electrolyte Balance	2008
Effects of arginine vasotocin and mesotocin on the activation and development of amiloride-blockable short-circuit current across larval, adult, and cultured larval bullfrog skins. Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 2010, Volume: 180, Issue:3 Topics: Adrenal Cortex Hormones; Amiloride; Animals; Antidiuretic Hormone Receptor Antagonists; Benzazepines; Colforsin; Electrophysiological Phenomena; Epithelial Sodium Channel Blockers; Epithelial Sodium Channels; Epithelium; Gene Expression; Larva; Oxytocin; Piperidines; Quinolones; Rana catesbeiana; Receptors, Oxytocin; Receptors, Pituitary Hormone; Receptors, Vasopressin; Skin; Vasotocin	2010
Mechanism of 1-deamino-arginine vasotocin induced natriuresis in rats. General and comparative endocrinology, 2011, Feb-01, Volume: 170, Issue:3 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Atrial Natriuretic Factor; Diuresis; Female; Furosemide; Natriuresis; Nitric Oxide; Piperidines; Quinolones; Rats; Rats, Wistar; Vasotocin	2011
Voluntary locomotion linked with cerebral activation is mediated by vasopressin V1a receptors in free-moving mice. The Journal of physiology, 2013, Jul-15, Volume: 591, Issue:14 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Arterial Pressure; Baroreflex; Heart Rate; Locomotion; Male; Mice, Inbred Strains; Mice, Knockout; Piperidines; Quinolones; Receptors, Vasopressin; Solitary Nucleus	2013
Effects of Long-term Blockade of Vasopressin Receptor Types 1a and 2 on Cardiac and Renal Damage in a Rat Model of Hypertensive Heart Failure. Journal of cardiovascular pharmacology, 2015, Volume: 66, Issue:5 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Benzazepines; Disease Models, Animal; Drug Therapy, Combination; Fibrosis; Gene Expression Regulation; Heart Failure; Heart Ventricles; Hemodynamics; Hypertension; Hypertrophy, Left Ventricular; Kidney; Kidney Diseases; Male; Piperidines; Quinolones; Rats, Inbred Dahl; Receptors, Vasopressin; Time Factors; Tolvaptan; Ventricular Function, Left; Ventricular Remodeling	2015