Compounds > opc 21268
Page last updated: 2024-09-02

opc 21268 and oxytocin

opc 21268 has been researched along with oxytocin in 8 studies

Compound Research Comparison

Studies
(opc 21268)		Trials
(opc 21268)		Recent Studies (post-2010)
(opc 21268)		Studies
(oxytocin)		Trials
(oxytocin)		Recent Studies (post-2010) (oxytocin)
1333621,6111,8315,773

Protein Interaction Comparison

ProteinTaxonomyopc 21268 (IC50)oxytocin (IC50)
Oxytocin receptorHomo sapiens (human)0.0027

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (62.50)18.2507
2000's2 (25.00)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Harrell, CM; Jasper, JR; O'Brien, JA; Pettibone, DJ1
Berti-Mattera, LN; Dulin, N; Mattera, R; Preston, JA; Thibonnier, M; Wilkins, PL1
Delisee, C; Dol, F; Garcia, C; Herbert, JM; Le Fur, G; Maffrand, JP; Marty, E; Raufaste, D; Schaeffer, P; Serradeil-Le Gal, C1
Andersen, LF; Atke, A; Barth, T; Hauzerova, L; Vilhardt, H1
Calò, G; Regoli, D; Rizzi, A; Traina, L1
Honda, K; Ikeda, K; Onaka, T; Yamashita, T1
Carlin, RW; Hagedorn, TM; Schultz, BD1
Fujimaki-Aoba, K; Hokari, S; Takada, M1

Other Studies

8 other study(ies) available for opc 21268 and oxytocin

ArticleYear
Characterization of the human oxytocin receptor stably expressed in 293 human embryonic kidney cells.
    Life sciences, 1995, Volume: 57, Issue:24

    Topics: Arginine Vasopressin; Cell Line; Drug Tolerance; Embryo, Mammalian; Female; Gene Expression; Guanine Nucleotides; Humans; Hydrolysis; Kidney; Myometrium; Oxytocin; Phosphatidylinositols; Receptors, Oxytocin; Recombinant Proteins; Transfection; Tritium

1995
The human V3 pituitary vasopressin receptor: ligand binding profile and density-dependent signaling pathways.
    Endocrinology, 1997, Volume: 138, Issue:10

    Topics: Animals; Arachidonic Acid; Base Sequence; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; CHO Cells; Cricetinae; Cyclic AMP; DNA; Dose-Response Relationship, Drug; Female; Humans; Ligands; Pertussis Toxin; Phenotype; Phosphorylation; Pituitary Gland; Protein Binding; Protein Kinase C; Receptors, Vasopressin; Signal Transduction; Thymidine; Tritium; Type C Phospholipases; Virulence Factors, Bordetella

1997
Effect of SR-49059, a vasopressin V1a antagonist, on human vascular smooth muscle cells.
    The American journal of physiology, 1995, Volume: 268, Issue:1 Pt 2

    Topics: Aorta; Arginine Vasopressin; Calcium; Cell Division; Cell Membrane; Cells, Cultured; Deamino Arginine Vasopressin; Dose-Response Relationship, Drug; Humans; Indoles; Iodine Radioisotopes; Kinetics; Muscle, Smooth, Vascular; Oxytocin; Piperidines; Pyrrolidines; Quinolones; Radioligand Assay; Receptors, Vasopressin; Vasopressins

1995
Effects of the non-peptide inhibitor OPC-21268 on oxytocin and vasopressin stimulation of rat and human myometrium.
    European journal of pharmacology, 1995, Jul-25, Volume: 281, Issue:1

    Topics: Anesthesia; Animals; Antidiuretic Hormone Receptor Antagonists; Cell Membrane; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; In Vitro Techniques; Myometrium; Oxytocin; Piperidines; Pregnancy; Quinolones; Rats; Receptors, Oxytocin; Receptors, Vasopressin; Sensitivity and Specificity; Stimulation, Chemical; Uterine Contraction; Vasopressins

1995
Pharmacological characterization of a vasopressin V1 receptor in the isolated human gastric artery.
    Life sciences, 1997, Volume: 60, Issue:4-5

    Topics: Aged; Aged, 80 and over; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Arteries; Benzazepines; Humans; In Vitro Techniques; Indoles; Middle Aged; Muscle, Smooth, Vascular; Oxytocin; Piperidines; Pyrrolidines; Quinolones; Receptors, Vasopressin; Stomach; Vasoconstrictor Agents

1997
Facilitative role of endogenous oxytocin in noradrenaline release in the rat supraoptic nucleus.
    The European journal of neuroscience, 2003, Volume: 18, Issue:11

    Topics: Analysis of Variance; Animals; Antidiuretic Hormone Receptor Antagonists; Brain Chemistry; Camphanes; Conditioning, Psychological; Dose-Response Relationship, Drug; Drug Interactions; Electrochemistry; Electroshock; Fear; Male; Microdialysis; Norepinephrine; Oxytocin; Piperazines; Piperidines; Potassium; Quinolones; Radioimmunoassay; Rats; Rats, Wistar; Receptors, Oxytocin; Stimulation, Chemical; Supraoptic Nucleus; Synaptosomes

2003
Oxytocin and vasopressin stimulate anion secretion by human and porcine vas deferens epithelia.
    Biology of reproduction, 2007, Volume: 77, Issue:3

    Topics: Alkaloids; Animals; Anions; Antidiuretic Hormone Receptor Antagonists; Benzophenanthridines; Cell Line; Cyclic AMP; Electrophysiology; Epithelial Cells; Humans; Ion Transport; Male; Oxytocin; Piperidines; Quinolones; Receptors, Oxytocin; Receptors, Vasopressin; Reverse Transcriptase Polymerase Chain Reaction; Swine; Vas Deferens; Vasopressins

2007
Effects of arginine vasotocin and mesotocin on the activation and development of amiloride-blockable short-circuit current across larval, adult, and cultured larval bullfrog skins.
    Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 2010, Volume: 180, Issue:3

    Topics: Adrenal Cortex Hormones; Amiloride; Animals; Antidiuretic Hormone Receptor Antagonists; Benzazepines; Colforsin; Electrophysiological Phenomena; Epithelial Sodium Channel Blockers; Epithelial Sodium Channels; Epithelium; Gene Expression; Larva; Oxytocin; Piperidines; Quinolones; Rana catesbeiana; Receptors, Oxytocin; Receptors, Pituitary Hormone; Receptors, Vasopressin; Skin; Vasotocin

2010