Page last updated: 2024-09-02

opc 21268 and l 371257

opc 21268 has been researched along with l 371257 in 2 studies

Compound Research Comparison

Studies (opc 21268)	Trials (opc 21268)	Recent Studies (post-2010) (opc 21268)	Studies (l 371257)	Trials (l 371257)	Recent Studies (post-2010) (l 371257)
133	3	6	23	0	8

Protein Interaction Comparison

Protein	Taxonomy	opc 21268 (IC50)	l 371257 (IC50)
Oxytocin receptor	Rattus norvegicus (Norway rat)		0.64

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (50.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	1 (50.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Clineschmidt, BV; Erb, JM; Freidinger, RM; Guidotti, MT; Lis, EV; Pawluczyk, JM; Pettibone, DJ; Reiss, DR; Veber, DF; Williams, PD	1
Borthwick, AD	1

Other Studies

2 other study(ies) available for opc 21268 and l 371257

Article	Year
1-(1-[4-[(N-acetyl-4-piperidinyl)oxy]-2-methoxybenzoyl]piperidin-4- yl)-4H-3,1-benzoxazin-2(1H)-one (L-371,257): a new, orally bioavailable, non-peptide oxytocin antagonist. Journal of medicinal chemistry, 1995, Nov-10, Volume: 38, Issue:23 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Benzoxazines; Biological Availability; Female; Humans; Kinetics; Molecular Structure; Obstetric Labor, Premature; Oxazines; Oxytocin; Piperidines; Pregnancy; Rats; Receptors, Oxytocin; Receptors, Vasopressin; Uterine Contraction	1995
Oral oxytocin antagonists. Journal of medicinal chemistry, 2010, Sep-23, Volume: 53, Issue:18 Topics: Administration, Oral; Animals; Biological Availability; Camphor; Humans; Indoles; Oxytocin; Piperazines; Piperidines; Protein Conformation; Pyrrolidines; Receptors, Oxytocin; Sulfonamides; Triazoles	2010

Article

Year

1-(1-[4-[(N-acetyl-4-piperidinyl)oxy]-2-methoxybenzoyl]piperidin-4- yl)-4H-3,1-benzoxazin-2(1H)-one (L-371,257): a new, orally bioavailable, non-peptide oxytocin antagonist.

Journal of medicinal chemistry, 1995, Nov-10, Volume: 38, Issue:23

Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Benzoxazines; Biological Availability; Female; Humans; Kinetics; Molecular Structure; Obstetric Labor, Premature; Oxazines; Oxytocin; Piperidines; Pregnancy; Rats; Receptors, Oxytocin; Receptors, Vasopressin; Uterine Contraction

1995

Oral oxytocin antagonists.

Journal of medicinal chemistry, 2010, Sep-23, Volume: 53, Issue:18

Topics: Administration, Oral; Animals; Biological Availability; Camphor; Humans; Indoles; Oxytocin; Piperazines; Piperidines; Protein Conformation; Pyrrolidines; Receptors, Oxytocin; Sulfonamides; Triazoles

2010