Page last updated: 2024-09-02

opc 21268 and arginine vasopressin

opc 21268 has been researched along with arginine vasopressin in 57 studies

Compound Research Comparison

Studies (opc 21268)	Trials (opc 21268)	Recent Studies (post-2010) (opc 21268)	Studies (arginine vasopressin)	Trials (arginine vasopressin)	Recent Studies (post-2010) (arginine vasopressin)
133	3	6	12,278	422	1,212

Protein Interaction Comparison

Protein	Taxonomy	opc 21268 (IC50)	arginine vasopressin (IC50)
Vasopressin V2 receptor	Homo sapiens (human)		0.242

Research

Studies (57)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	49 (85.96)	18.2507
2000's	8 (14.04)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Harrell, CM; Jasper, JR; O'Brien, JA; Pettibone, DJ	1
Berti-Mattera, LN; Dulin, N; Mattera, R; Preston, JA; Thibonnier, M; Wilkins, PL	1
Hirata, Y; Kohmoto, O; Matsui, H; Serizawa, T	1
Harada, S; Hirooka, Y; Imaizumi, T; Masaki, H; Momohara, M; Takeshita, A	2
Endoh, M; Norota, I; Takanashi, M	1
Chiba, S; Tsukada, M	1
Chiba, S; Furukawa, Y; Inoue, Y; Ren, LM; Sawaki, S; Takayama, S	1
Ishikawa, S; Okada, K; Saito, T	1
Chihara, T; Kondo, K; Mori, T; Nakamura, S; Ogawa, H; Onogawa, T; Tominaga, M; Yabuuchi, Y; Yamamura, Y	1
Chihara, T; Mori, T; Nakamura, S; Onogawa, T; Tominaga, M; Yabuuchi, Y; Yamamura, Y; Yamashita, T	1
Nakanishi, T; Nanbu, A; Nishimura, M; Sakamoto, M; Takahashi, H; Yoshimura, M	3
Asano, N; Harada, K; Hashimoto, M; Kageyama, J; Mimura, Y; Ogura, T; Oishi, T; Ota, Z; Yamauchi, T	1
Arakawa, K; Ichihara, A; Matsumoto, A; Murakami, M; Naitoh, M; Nakamoto, H; Oka, K; Saruta, T; Suzuki, H; Yamamura, Y	1
Burrell, LM; Buxton, BF; Johnston, CI; Liu, JJ; Phillips, PA; Rolls, KA	1
Delisee, C; Dol, F; Garcia, C; Herbert, JM; Le Fur, G; Maffrand, JP; Marty, E; Raufaste, D; Schaeffer, P; Serradeil-Le Gal, C	1
Donald, RA; Ellis, MJ; Evans, MJ; Mulligan, RS	1
Abe, Y; Aki, Y; Fujisawa, Y; Hayashida, Y; Kimura, S; Miyatake, A; Tamaki, T	1
Burrell, LM; Buxton, BB; Johnston, CI; Liu, JJ; Phillips, PA	1
Ban, Y; Honda, K; Ishiharada, N; Kamiya, H; Saito, R; Takano, Y	1
Bourrié, B; Carayon, P; Casellas, P; Garcia, C; Le Fur, G; Maffrand, JP; Raufaste, D; Serradeil-Le Gal, C	1
Ishikawa, S; Okada, K; Saito, T; Sasaki, R	1
Burrell, LM; Johnston, CI; Phillips, PA; Risvanis, J; Rolls, KA; Stephenson, JM	1
Burrell, LM; Hutchins, AM; Johnston, CI; Phillips, PA; Risvanis, J; Stephenson, J	2
Ichihara, A; Matsumoto, A; Murakami, M; Naitoh, M; Nakamoto, H; Saruta, T; Suzuki, H; Yamamura, Y	1
Chihara, T; Mori, T; Nakamura, S; Onogawa, T; Tominaga, M; Yabuuchi, Y; Yamada, Y; Yamamura, Y; Yamashita, T	1
Kribben, A; Li, X; Nemenoff, RA; Schrier, RW; Tsai, P; Wieder, ED	1
Jamil, KM; Kurokawa, K; Nakao, A; Okuda, T; Watanabe, T	1
Christophe, B; Garcia, C; Guiraudou, P; Lacour, C; Le Fur, G; Maffrand, JP; Nisato, D; Serradeil-Le Gal, C; Villanova, G; Wagnon, J	1
Miura, Y; Nakano, H; Nakayama, M; Suzuki, S; Tuchida, H; Yamada, K; Yoshida, S	1
Miura, Y; Nakano, H; Nakayama, M; Suzuki, S; Tsuchida, H; Yamada, K; Yoshida, S	1
Hirai, S; Kosaka, K; Mizuno, K; Nishioka, N; Ohno, S; Osada, S; Suzuki, A	1
Bax, WA; Bos, E; Nisato, D; Saxena, PR; Stam, WB; Van der Graaf, PH	1
Abe, K; Hashimoto, J; Imai, Y; Minami, N; Munakata, M	1
Hanaoka, K; Imai, M; Kurokawa, K; Naruse, M; Yamamura, Y; Yoshitomi, K	1
Iizuka, T; Nishikawa, T; Omura, M; Saito, I; Yoshida, S	1
Calò, G; Regoli, D; Rizzi, A; Traina, L	1
Goto, A; Hayakawa, H; Hirata, Y; Hirobe, M; Kakoki, M; Kikuchi, K; Kimura, K; Nagano, T; Nagata, D; Omata, M; Suzuki, E; Tojo, A	1
Aldred, KL; Burrell, LM; Johnston, CI; Naitoh, M; Phillips, PA; Risvanis, J; Rockell, MD	1
Ishii, N; Kusayama, T; Tahara, A; Tanaka, A; Tomura, Y; Tsukada, J; Uchida, W; Wada, K; Yatsu, T	1
Charles, CJ; Donald, RA; Ikram, H; Prickett, T; Richards, AM	1
Saxena, PR; Stam, WB; Van der Graaf, PH	1
Daidoh, H; Hanafusa, J; Ishizuka, T; Morita, H; Mune, T; Murase, H; Sato, M; Shibata, T; Suwa, T; Yasuda, K	1
Iijima, T; Ishikawa, K; Kurata, S	1
Fukuzawa, J; Haneda, T; Kikuchi, K	1
Fujisawa, S; Iijima, T	1
Coles, P; Conarty, DM; Plesnicher, CL; Shoham, M; Thibonnier, M	1
Ishiguro, S; Iwasaki, T; Miyamoto, A; Mori, T; Nishio, A	1
Ikebe, M; Kohda, Y; Machida, K; Nonoguchi, H; Star, RA; Tashima, Y; Tomita, K	1
Arima, H; Hirabayashi, M; Miura, Y; Murase, T; Nagasaki, H; Oiso, Y; Sugimura, Y; Tachikawa, K; Yokoi, H	1
Aukland, K; Roald, AB; Tenstad, O	1
Ishikawa, SE; Sasaki, M	1
Aoyagi, T; Hiroyama, M; Oikawa, R; Sanbe, A; Takeo, S; Tanoue, A; Wang, S	1
Cowley, AW; O'Connor, PM	1

Reviews

1 review(s) available for opc 21268 and arginine vasopressin

Article	Year
[Renal action of vasopressin]. Nihon rinsho. Japanese journal of clinical medicine, 2006, Volume: 64 Suppl 2 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Aquaporin 2; Arginine Vasopressin; Benzazepines; Diabetes Insipidus; Diabetes Insipidus, Nephrogenic; Drug Design; Humans; Hyponatremia; Inappropriate ADH Syndrome; Mutation; Piperidines; Quinolones; Receptors, Vasopressin	2006

Trials

1 trial(s) available for opc 21268 and arginine vasopressin

Article	Year
Short-term clinical trial of 1-(1-[4-(3-acetylaminopropoxy)-benzoyl]-4-piperidyl)-3, 4-dihydro-2(1H)-quinolinone in patients with diabetic nephropathy. Possible effectiveness of the specific vasopressin V1 receptor antagonist for reducing albuminuria in p Arzneimittel-Forschung, 1996, Volume: 46, Issue:9 Topics: Albuminuria; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Blood Glucose; Blood Pressure; Creatinine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Heart Rate; Humans; Male; Middle Aged; Piperidines; Quinolones; Saline Solution, Hypertonic	1996

Article

Year

Short-term clinical trial of 1-(1-[4-(3-acetylaminopropoxy)-benzoyl]-4-piperidyl)-3, 4-dihydro-2(1H)-quinolinone in patients with diabetic nephropathy. Possible effectiveness of the specific vasopressin V1 receptor antagonist for reducing albuminuria in p

Arzneimittel-Forschung, 1996, Volume: 46, Issue:9

Topics: Albuminuria; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Blood Glucose; Blood Pressure; Creatinine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Heart Rate; Humans; Male; Middle Aged; Piperidines; Quinolones; Saline Solution, Hypertonic

1996

Other Studies

55 other study(ies) available for opc 21268 and arginine vasopressin

Article	Year
Characterization of the human oxytocin receptor stably expressed in 293 human embryonic kidney cells. Life sciences, 1995, Volume: 57, Issue:24 Topics: Arginine Vasopressin; Cell Line; Drug Tolerance; Embryo, Mammalian; Female; Gene Expression; Guanine Nucleotides; Humans; Hydrolysis; Kidney; Myometrium; Oxytocin; Phosphatidylinositols; Receptors, Oxytocin; Recombinant Proteins; Transfection; Tritium	1995
The human V3 pituitary vasopressin receptor: ligand binding profile and density-dependent signaling pathways. Endocrinology, 1997, Volume: 138, Issue:10 Topics: Animals; Arachidonic Acid; Base Sequence; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; CHO Cells; Cricetinae; Cyclic AMP; DNA; Dose-Response Relationship, Drug; Female; Humans; Ligands; Pertussis Toxin; Phenotype; Phosphorylation; Pituitary Gland; Protein Binding; Protein Kinase C; Receptors, Vasopressin; Signal Transduction; Thymidine; Tritium; Type C Phospholipases; Virulence Factors, Bordetella	1997
Effects of a nonpeptide vasopressin antagonist (OPC-21268) on cytosolic Ca2+ concentration in vascular and cardiac myocytes. Hypertension (Dallas, Tex. : 1979), 1992, Volume: 19, Issue:6 Pt 2 Topics: Animals; Arginine Vasopressin; Calcium; Cytosol; Muscle, Smooth, Vascular; Myocardium; Osmolar Concentration; Piperidines; Quinolones; Vasopressins	1992
Effects of OPC-21268, an orally effective vasopressin V1 receptor antagonist in humans. Hypertension (Dallas, Tex. : 1979), 1992, Volume: 20, Issue:1 Topics: Administration, Oral; Adult; Angiotensin Receptor Antagonists; Arginine Vasopressin; Dose-Response Relationship, Drug; Forearm; Humans; Injections, Intra-Arterial; Male; Phenylephrine; Piperidines; Quinolones; Receptors, Vasopressin; Regional Blood Flow; Vascular Resistance	1992
Effects of vasopressin on phosphoinositide hydrolysis and myocardial contractility. European journal of pharmacology, 1992, Aug-06, Volume: 218, Issue:2-3 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Heart Ventricles; Hydrolysis; In Vitro Techniques; Male; Myocardial Contraction; Phosphatidylinositols; Piperidines; Quinolones; Rabbits; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta	1992
Potent antagonistic action of OPC-31260, a vasopressin V2 receptor antagonist, on [Arg8]vasopressin-induced vasoconstriction in isolated simian femoral arteries. European journal of pharmacology, 1992, Oct-20, Volume: 221, Issue:2-3 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Benzazepines; Female; Femoral Artery; In Vitro Techniques; Macaca; Male; Norepinephrine; Piperidines; Quinolones; Vasoconstriction	1992
Blocking effects of V1 (OPC-21268) and V2 (OPC-31260) antagonists on the negative inotropic response to vasopressin in isolated dog heart preparations. The Journal of pharmacology and experimental therapeutics, 1992, Volume: 263, Issue:2 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Benzazepines; Deamino Arginine Vasopressin; Dogs; Heart; Heart Atria; Perfusion; Piperidines; Quinolones; Receptors, Vasopressin	1992
Effect of a new V1 antagonist (OPC-21268) on vascular action of vasopressin in cultured rat vascular smooth muscle cells. Biochemical and biophysical research communications, 1991, Jul-31, Volume: 178, Issue:2 Topics: Angiotensin II; Animals; Aorta, Thoracic; Arginine Vasopressin; Calcium; Cells, Cultured; Kinetics; Male; Muscle, Smooth, Vascular; Piperidines; Quinolones; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Receptors, Vasopressin	1991
OPC-21268, an orally effective, nonpeptide vasopressin V1 receptor antagonist. Science (New York, N.Y.), 1991, Apr-26, Volume: 252, Issue:5005 Topics: Administration, Oral; Angiotensin II; Animals; Arginine Vasopressin; Binding, Competitive; Blood Pressure; Cell Membrane; Kidney; Kinetics; Liver; Norepinephrine; Piperidines; Quinolones; Rats; Receptors, Angiotensin; Receptors, Vasopressin; Time Factors	1991
OPC-21268 antagonizes arginine vasopressin-induced vasoconstrictor response in the spinally-anesthetized dog. Japanese journal of pharmacology, 1995, Volume: 68, Issue:3 Topics: Animals; Arginine Vasopressin; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Injections, Intravenous; Piperidines; Quinolones; Vasoconstriction	1995
Cerebral ATP-sensitive potassium channels during acute reduction of carotid blood flow. Hypertension (Dallas, Tex. : 1979), 1995, Volume: 25, Issue:5 Topics: Adenosine Triphosphate; Animals; Arginine Vasopressin; Blood Pressure; Brain; Carotid Arteries; Glyburide; Male; Piperidines; Pituitary Gland; Potassium Channels; Quinolones; Rats; Rats, Wistar; Regional Blood Flow	1995
Enhanced pressor response in spontaneously hypertensive rats induced by stimulation of vasopressin-V1 receptors. Acta medica Okayama, 1995, Volume: 49, Issue:1 Topics: Animals; Arginine Vasopressin; Benzazepines; Blood Pressure; Heart Rate; Hypertension; Male; Piperidines; Quinolones; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Vasopressin; Stimulation, Chemical	1995
Effects of oral AVP receptor antagonists OPC-21268 and OPC-31260 on congestive heart failure in conscious dogs. The American journal of physiology, 1994, Volume: 267, Issue:6 Pt 2 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Benzazepines; Body Weight; Capillary Resistance; Cardiac Output; Cardiac Pacing, Artificial; Diuresis; Dogs; Heart Failure; Hemodynamics; Kidney; Male; Natriuresis; Osmolar Concentration; Piperidines; Potassium; Quinolones; Renin; Sodium	1994
Vascular responses to vasopressin antagonists in man and rat. Clinical science (London, England : 1979), 1994, Volume: 87, Issue:4 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Benzazepines; Culture Techniques; Dose-Response Relationship, Drug; Female; Humans; Mammary Arteries; Mesenteric Artery, Superior; Piperidines; Quinolones; Rats; Rats, Sprague-Dawley; Species Specificity; Vasoconstriction	1994
Effect of SR-49059, a vasopressin V1a antagonist, on human vascular smooth muscle cells. The American journal of physiology, 1995, Volume: 268, Issue:1 Pt 2 Topics: Aorta; Arginine Vasopressin; Calcium; Cell Division; Cell Membrane; Cells, Cultured; Deamino Arginine Vasopressin; Dose-Response Relationship, Drug; Humans; Indoles; Iodine Radioisotopes; Kinetics; Muscle, Smooth, Vascular; Oxytocin; Piperidines; Pyrrolidines; Quinolones; Radioligand Assay; Receptors, Vasopressin; Vasopressins	1995
The effects of corticotrophin-releasing hormone, arginine vasopressin and their antagonists on ACTH release from perifused horse anterior pituitary cells. The Journal of endocrinology, 1994, Volume: 143, Issue:1 Topics: Adrenocorticotropic Hormone; Animals; Arginine Vasopressin; Biological Assay; Cells, Cultured; Corticotropin-Releasing Hormone; Dose-Response Relationship, Drug; Drug Synergism; Female; Horses; Male; Piperidines; Pituitary Gland, Anterior; Quinolones	1994
Role of vasopressin on cardiovascular changes during hemorrhage in conscious rats. The American journal of physiology, 1994, Volume: 267, Issue:5 Pt 2 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Benzazepines; Blood Pressure; Heart Rate; Hemorrhage; In Vitro Techniques; Kidney; Male; Piperidines; Quinolones; Rats; Rats, Sprague-Dawley; Renal Artery; Sympathetic Nervous System; Time Factors	1994
Human internal mammary artery responses to non-peptide vasopressin antagonists. Clinical and experimental pharmacology & physiology, 1994, Volume: 21, Issue:2 Topics: Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Arteries; Benzazepines; Breast; Female; Humans; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Piperidines; Quinolones; Receptors, Vasopressin; Regional Blood Flow	1994
Vasopressin V1 receptor in rat hippocampus is regulated by adrenocortical functions. Brain research, 1994, May-16, Volume: 646, Issue:1 Topics: Adrenal Cortex; Adrenalectomy; Aldosterone; Animals; Arginine Vasopressin; Corticosterone; Dexamethasone; Hippocampus; Male; Piperidines; Quinolones; Rats; Rats, Wistar; Receptors, Vasopressin	1994
Effect of a new, potent, non-peptide V1a vasopressin antagonist, SR 49059, on the binding and the mitogenic activity of vasopressin on Swiss 3T3 cells. Biochemical pharmacology, 1994, Feb-11, Volume: 47, Issue:4 Topics: 3T3 Cells; Animals; Arginine Vasopressin; Binding Sites; Cell Division; DNA; Flow Cytometry; Indoles; Mice; Mitogens; Piperidines; Pyrrolidines; Quinolones; Receptors, Vasopressin	1994
Distinct inhibition by non-peptide and peptide arginine vasopressin antagonists of vasopressin-induced activation of mitogen-activated protein kinase in cultured rat vascular smooth muscle cells. Biochemical and biophysical research communications, 1994, Apr-29, Volume: 200, Issue:2 Topics: Angiotensin II; Animals; Arginine Vasopressin; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Enzyme Activation; Ionomycin; Muscle, Smooth, Vascular; Piperidines; Quinolones; Rats; Tetradecanoylphorbol Acetate	1994
Blood pressure-lowering effect of an orally active vasopressin V1 receptor antagonist in mineralocorticoid hypertension in the rat. Hypertension (Dallas, Tex. : 1979), 1994, Volume: 23, Issue:6 Pt 1 Topics: Administration, Oral; Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Binding Sites; Blood Pressure; Desoxycorticosterone; Female; Hypertension; Kinetics; Mesenteric Arteries; Piperidines; Quinolones; Rats; Rats, Sprague-Dawley; Receptors, Vasopressin; Sodium Chloride; Systole; Vascular Resistance	1994
Characterization of a novel non-peptide vasopressin V1 receptor antagonist (OPC-21268) in the rat. The Journal of endocrinology, 1993, Volume: 138, Issue:2 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Kidney Medulla; Liver; Piperidines; Protein Binding; Quinolones; Radioligand Assay; Rats; Rats, Sprague-Dawley; Time Factors	1993
Arginine vasopressin produces renal vasodilation via V2 receptors in conscious dogs. The American journal of physiology, 1993, Volume: 265, Issue:4 Pt 2 Topics: Animals; Arginine Vasopressin; Benzazepines; Deamino Arginine Vasopressin; Diuresis; Dogs; Drug Combinations; Hemodynamics; Male; Natriuresis; Osmolar Concentration; Piperidines; Quinolones; Receptors, Vasopressin; Renal Circulation; Vasodilation	1993
OPC-21268, a vasopressin V1 antagonist, produces hypotension in spontaneously hypertensive rats. Hypertension (Dallas, Tex. : 1979), 1994, Volume: 23, Issue:2 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Blood Pressure; Hypertension; Male; Piperidines; Quinolones; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley	1994
Inhibition of vasopressin action in vascular smooth muscle by the V1 antagonist OPC-21268. Hypertension (Dallas, Tex. : 1979), 1994, Volume: 23, Issue:2 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Calcium; Cells, Cultured; Male; Mitogen-Activated Protein Kinase 1; Muscle, Smooth, Vascular; Piperidines; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Quinolones; Rats; Rats, Sprague-Dawley	1994
Distinct mechanisms of action of V1 antagonists OPC-21268 and [d(CH2)5Tyr(Me)AVP] in mesangial cells. Biochemical and biophysical research communications, 1993, Jun-15, Volume: 193, Issue:2 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Calcium; Cells, Cultured; Deamino Arginine Vasopressin; Dose-Response Relationship, Drug; Glomerular Mesangium; Kinetics; Piperidines; Quinolones; Rats; Receptors, Vasopressin	1993
Effects of a novel orally effective V1-receptor antagonist, OPC-21268, on AVP-induced sympathoinhibition. The American journal of physiology, 1993, Volume: 264, Issue:6 Pt 2 Topics: Administration, Oral; Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Blood Pressure; Heart Rate; Injections, Intravenous; Kidney; Male; Neural Inhibition; Phenylephrine; Piperidines; Quinolones; Rabbits; Sympathetic Nervous System; Vasopressins	1993
Effects of an orally active vasopressin V1 receptor antagonist. Clinical and experimental pharmacology & physiology, 1993, Volume: 20, Issue:5 Topics: Administration, Oral; Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Binding Sites; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Kidney; Liver; Piperidines; Quinolones; Rats; Rats, Sprague-Dawley; Receptors, Vasopressin	1993
Biochemical and pharmacological properties of SR 49059, a new, potent, nonpeptide antagonist of rat and human vasopressin V1a receptors. The Journal of clinical investigation, 1993, Volume: 92, Issue:1 Topics: Animals; Arginine Vasopressin; Cattle; Cell Membrane; Humans; In Vitro Techniques; Indoles; Muscle Contraction; Piperidines; Platelet Aggregation; Pyrrolidines; Quinolones; Rats; Receptors, Vasopressin	1993
A lack of anti-hypertensive effect of an orally effective V1 receptor antagonist, OPC-21268, in end-stage renal disease. Clinical nephrology, 1993, Volume: 40, Issue:1 Topics: Adult; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Blood Pressure; Female; Humans; Hypertension, Renal; Kidney Failure, Chronic; Male; Middle Aged; Piperidines; Quinolones	1993
The effect of OPC-21268, an oral, nonpeptide arginine vasopressin V1 receptor antagonist, on a patient with congestive heart failure. Clinical nephrology, 1993, Volume: 40, Issue:1 Topics: Adult; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Blood Pressure; Diabetes Mellitus, Type 2; Female; Heart Failure; Heart Rate; Humans; Kidney Failure, Chronic; Piperidines; Quinolones	1993
Wortmannin inhibits the activation of MAP kinase following vasopressin V1 receptor stimulation. FEBS letters, 1995, Dec-27, Volume: 377, Issue:3 Topics: Androstadienes; Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Benzazepines; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Deamino Arginine Vasopressin; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Fibroblasts; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Piperidines; Quinolones; Rats; Receptors, Vasopressin; Signal Transduction; Tetradecanoylphorbol Acetate; Wortmannin	1995
[Arg8]vasopressin-induced responses of the human isolated coronary artery: effects of non-peptide receptor antagonists. European journal of pharmacology, 1995, Oct-16, Volume: 285, Issue:2 Topics: Adolescent; Adult; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Benzazepines; Child; Coronary Vessels; Endothelium, Vascular; Female; Humans; In Vitro Techniques; Indoles; Male; Middle Aged; Muscle, Smooth, Vascular; Piperidines; Potassium; Pyrrolidines; Quinolones; Vasoconstrictor Agents	1995
Effects of vasopressin V1 and V2 receptor antagonists on the development of salt-induced hypertension in Dahl rats. Journal of cardiovascular pharmacology, 1995, Volume: 26, Issue:4 Topics: Analysis of Variance; Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Benzazepines; Blood Pressure; Blood Pressure Determination; Diuresis; Hypertension; Male; Piperidines; Quinolones; Rats; Sodium Chloride	1995
Cerebral adenosine triphosphate-sensitive K+ channels may be impaired during acute cerebral ischemia in spontaneously hypertensive rats. Journal of the autonomic nervous system, 1996, May-06, Volume: 58, Issue:3 Topics: Adenosine Triphosphate; Adrenergic alpha-Antagonists; Animals; Antidiuretic Hormone Receptor Antagonists; Antihypertensive Agents; Arginine Vasopressin; Arterial Occlusive Diseases; Blood Pressure; Brain Ischemia; Carotid Arteries; Cerebral Cortex; Glyburide; Guanidines; Hypertension; Hypoglycemic Agents; Injections, Intravenous; Injections, Intraventricular; Ligation; Male; Pinacidil; Piperidines; Potassium Channels; Quinolones; Rats; Rats, Inbred SHR; Rats, Inbred WKY	1996
Functional characterization of vasopressin V1 and V2 receptors in the rabbit renal cortical collecting duct. Kidney international. Supplement, 1996, Volume: 55 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Benzazepines; Calcium; Cyclic AMP; Electrophysiology; In Vitro Techniques; Kidney Cortex; Kidney Tubules, Collecting; Male; Membrane Potentials; Patch-Clamp Techniques; Piperidines; Quinolones; Rabbits; Receptors, Vasopressin; Renal Agents; Sodium	1996
Pharmacological characterization of a vasopressin V1 receptor in the isolated human gastric artery. Life sciences, 1997, Volume: 60, Issue:4-5 Topics: Aged; Aged, 80 and over; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Arteries; Benzazepines; Humans; In Vitro Techniques; Indoles; Middle Aged; Muscle, Smooth, Vascular; Oxytocin; Piperidines; Pyrrolidines; Quinolones; Receptors, Vasopressin; Stomach; Vasoconstrictor Agents	1997
Receptor subtype for vasopressin-induced release of nitric oxide from rat kidney. Hypertension (Dallas, Tex. : 1979), 1997, Volume: 29, Issue:1 Pt 1 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Benzazepines; Desoxycorticosterone; Dinoprost; Dose-Response Relationship, Drug; Enzyme Inhibitors; In Vitro Techniques; Kidney; Male; Nitric Oxide; omega-N-Methylarginine; Perfusion; Piperidines; Quinolones; Rats; Rats, Wistar; Receptors, Vasopressin; Renal Agents	1997
Role of cerebral ATP-sensitive K+ channels in arterial pressure regulation during acute cerebral ischaemia in SHR and WKY rats. Clinical and experimental pharmacology & physiology. Supplement, 1995, Volume: 22, Issue:1 Topics: Adenosine Triphosphate; Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Blood Pressure; Brain Chemistry; Brain Ischemia; Glyburide; Hypoglycemic Agents; Injections, Intraventricular; Male; Piperidines; Pituitary Gland; Potassium Channels; Quinolones; Rats; Rats, Inbred SHR; Rats, Inbred WKY	1995
Modulation of genetic hypertension by short-term AVP V1A or V2 receptor antagonism in young SHR. The American journal of physiology, 1997, Volume: 272, Issue:2 Pt 2 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Benzazepines; Blood Pressure; Hypertension; Male; Myocardium; Organ Size; Piperidines; Quinolones; Ramipril; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Systole; Time Factors	1997
Effect of YM087, a potent nonpeptide vasopressin antagonist, on vasopressin-induced protein synthesis in neonatal rat cardiomyocyte. Cardiovascular research, 1998, Volume: 38, Issue:1 Topics: Analysis of Variance; Animals; Animals, Newborn; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Benzazepines; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Leucine; Myocardium; Piperidines; Protein Biosynthesis; Quinolones; Rats; Rats, Wistar; Receptors, Vasopressin; Stimulation, Chemical; Thymidine	1998
Arginine vasopressin V1-receptor antagonism in an ovine model of acute myocardial infarction. Journal of cardiovascular pharmacology, 1998, Volume: 32, Issue:5 Topics: Adrenocorticotropic Hormone; Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Corticotropin-Releasing Hormone; Female; Halothane; Hemodynamics; Myocardial Infarction; Piperidines; Quinolones; Renin; Sheep	1998
Characterization of receptors mediating contraction of the rat isolated small mesenteric artery and aorta to arginine vasopressin and oxytocin. British journal of pharmacology, 1998, Volume: 125, Issue:4 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Aorta; Arginine Vasopressin; Dose-Response Relationship, Drug; Hormone Antagonists; In Vitro Techniques; Indoles; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Piperidines; Pyrrolidines; Quinolones; Rats; Rats, Wistar; Receptors, Oxytocin; Receptors, Vasopressin; Vasotocin	1998
In vivo and in vitro effects of AVP and V1a receptor antagonist on Cushing's syndrome due to ACTH-independent bilateral macronodular adrenocortical hyperplasia. Clinical endocrinology, 1998, Volume: 49, Issue:3 Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Cells, Cultured; Cushing Syndrome; Diuretics; Drug Administration Schedule; Furosemide; Gastric Inhibitory Polypeptide; Humans; Hydrocortisone; Hyperplasia; Injections, Intravenous; Insulin; Male; Middle Aged; Piperidines; Posture; Quinolones	1998
Enhancement by arginine vasopressin of the L-type Ca2+ current in guinea pig ventricular myocytes. Pharmacology, 1999, Volume: 59, Issue:1 Topics: Animals; Arginine Vasopressin; Calcium; Calcium Channels; Calcium Channels, L-Type; Dose-Response Relationship, Drug; Guinea Pigs; Heart; Isoproterenol; Piperidines; Potassium Channels; Quinolones	1999
Arginine vasopressin increases the rate of protein synthesis in isolated perfused adult rat heart via the V1 receptor. Molecular and cellular biochemistry, 1999, Volume: 195, Issue:1-2 Topics: Amiloride; Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Calcium; Cyclic AMP; In Vitro Techniques; Male; Myocardium; Peptide Biosynthesis; Perfusion; Piperidines; Pressure; Quinolones; Rats; Rats, Sprague-Dawley; Receptors, Vasopressin	1999
On the inotropic actions of arginine vasopressin in ventricular muscle of the guinea pig heart. Japanese journal of pharmacology, 1999, Volume: 81, Issue:3 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Guinea Pigs; Heart Ventricles; In Vitro Techniques; Membrane Potentials; Myocardial Contraction; Piperidines; Quinolones; Staurosporine; Ventricular Function	1999
A molecular model of agonist and nonpeptide antagonist binding to the human V(1) vascular vasopressin receptor. The Journal of pharmacology and experimental therapeutics, 2000, Volume: 294, Issue:1 Topics: Amino Acid Sequence; Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Humans; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Piperidines; Quinolones; Radioligand Assay; Rats; Receptors, Vasopressin	2000
Vasopressin receptor subtypes on mesenteric and cremasteric arterioles in rat. European journal of pharmacology, 2000, Jul-14, Volume: 400, Issue:1 Topics: Animals; Arginine Vasopressin; Arterioles; Benzazepines; Male; Mesenteric Arteries; Muscle, Skeletal; Piperidines; Quinolones; Rats; Rats, Wistar; Receptors, Vasopressin; Vasoconstriction	2000
Intranephron localization and regulation of the V1a vasopressin receptor during chronic metabolic acidosis and dehydration in rats. Pflugers Archiv : European journal of physiology, 2001, Volume: 442, Issue:5 Topics: Acidosis; Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Bicarbonates; Dehydration; Down-Regulation; Homeostasis; Immunohistochemistry; Male; Nephrons; Piperidines; Polymerase Chain Reaction; Quinolones; Rats; Rats, Sprague-Dawley; Receptors, Vasopressin; RNA, Messenger; Up-Regulation; Vacuolar Proton-Translocating ATPases	2001
Altered cardiovascular regulation in arginine vasopressin-overexpressing transgenic rat. American journal of physiology. Endocrinology and metabolism, 2003, Volume: 285, Issue:6 Topics: Adaptation, Physiological; Animals; Animals, Genetically Modified; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Blood Pressure; Carotid Artery Diseases; Hemorrhage; Hemostasis; Male; Piperidines; Quinolones; Rats; Rats, Sprague-Dawley; Receptors, Vasopressin	2003
The effect of AVP-V receptor stimulation on local GFR in the rat kidney. Acta physiologica Scandinavica, 2004, Volume: 182, Issue:2 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Diuresis; Female; Glomerular Filtration Rate; Kidney; Kidney Cortex; Ornipressin; Piperidines; Quinolones; Rats; Rats, Sprague-Dawley; Receptors, Vasopressin	2004
Vasopressin promotes cardiomyocyte hypertrophy via the vasopressin V1A receptor in neonatal mice. European journal of pharmacology, 2007, Mar-22, Volume: 559, Issue:2-3 Topics: Animals; Animals, Newborn; Arginine Vasopressin; Atrial Natriuretic Factor; Cardiomegaly; Cell Enlargement; Cells, Cultured; Disease Models, Animal; DNA; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Immunohistochemistry; Male; Mice; Mice, Knockout; Myocytes, Cardiac; Phosphorylation; Piperidines; Protein Biosynthesis; Quinolones; Receptors, Vasopressin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Transcription, Genetic; Vasoconstrictor Agents	2007
Vasopressin-induced nitric oxide production in rat inner medullary collecting duct is dependent on V2 receptor activation of the phosphoinositide pathway. American journal of physiology. Renal physiology, 2007, Volume: 293, Issue:2 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Benzazepines; Calcium; Calcium-Transporting ATPases; Cyclic AMP-Dependent Protein Kinases; Kidney Medulla; Kidney Tubules, Collecting; Male; Nitric Oxide; Phosphatidylinositols; Piperidines; Quinolones; Rats; Rats, Sprague-Dawley; Receptors, Vasopressin; Signal Transduction; Spectrometry, Fluorescence; Type C Phospholipases; Vasopressins	2007