opc 21268 has been researched along with angiotensin ii in 3 studies
| Studies (opc 21268) | Trials (opc 21268) | Recent Studies (post-2010) (opc 21268) | Studies (angiotensin ii) | Trials (angiotensin ii) | Recent Studies (post-2010) (angiotensin ii) |
|---|---|---|---|---|---|
| 133 | 3 | 6 | 38,152 | 1,089 | 7,413 |
| Protein | Taxonomy | opc 21268 (IC50) | angiotensin ii (IC50) |
|---|---|---|---|
| Atrial natriuretic peptide receptor 3 | Homo sapiens (human) | 0.002 | |
| Type-1A angiotensin II receptor | Rattus norvegicus (Norway rat) | 0.002 | |
| Type-1B angiotensin II receptor | Rattus norvegicus (Norway rat) | 0.0018 | |
| Type-1 angiotensin II receptor | Homo sapiens (human) | 0.0055 | |
| Type-2 angiotensin II receptor | Rattus norvegicus (Norway rat) | 0.004 | |
| Type-2 angiotensin II receptor | Homo sapiens (human) | 0.0011 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ishikawa, S; Okada, K; Saito, T | 1 |
| Chihara, T; Kondo, K; Mori, T; Nakamura, S; Ogawa, H; Onogawa, T; Tominaga, M; Yabuuchi, Y; Yamamura, Y | 1 |
| Ishikawa, S; Okada, K; Saito, T; Sasaki, R | 1 |
3 other study(ies) available for opc 21268 and angiotensin ii
| Article | Year |
|---|---|
Effect of a new V1 antagonist (OPC-21268) on vascular action of vasopressin in cultured rat vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Arginine Vasopressin; Calcium; Cells, Cultured; Kinetics; Male; Muscle, Smooth, Vascular; Piperidines; Quinolones; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Receptors, Vasopressin | 1991 |
OPC-21268, an orally effective, nonpeptide vasopressin V1 receptor antagonist.
Topics: Administration, Oral; Angiotensin II; Animals; Arginine Vasopressin; Binding, Competitive; Blood Pressure; Cell Membrane; Kidney; Kinetics; Liver; Norepinephrine; Piperidines; Quinolones; Rats; Receptors, Angiotensin; Receptors, Vasopressin; Time Factors | 1991 |
Distinct inhibition by non-peptide and peptide arginine vasopressin antagonists of vasopressin-induced activation of mitogen-activated protein kinase in cultured rat vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Arginine Vasopressin; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Enzyme Activation; Ionomycin; Muscle, Smooth, Vascular; Piperidines; Quinolones; Rats; Tetradecanoylphorbol Acetate | 1994 |