Page last updated: 2024-08-16

opc 12759 and mocetinostat

opc 12759 has been researched along with mocetinostat in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (57.14)18.2507
2000's6 (42.86)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hong, KW; Kim, CD1
Harada, N; Johno, M; Murakami, K; Okabe, H; Okajima, K; Takatsuki, K; Uchiba, M1
Ichikawa, H; Kokura, S; Kondo, M; Naito, Y; Takahashi, S; Takano, H; Tomii, T; Yoshida, N; Yoshikawa, T1
Boku, Y; Fujii, T; Iinuma, S; Kondo, M; Matsuyama, K; Naito, Y; Sasaki, E; Yagi, N; Yoshida, N; Yoshikawa, T1
Harada, N; Isobe, H; Murakami, K; Okabe, H; Okajima, K1
Iwai, A; Iwashita, E1
Hong, KW; Kim, CD; Kim, KE; Lee, WS; Rhim, BY1
Fitzpatrick, LR; Le, T; Sakurai, K1
Haruma, K; Kishimoto, S; Nakagawa, Y; Nakano, M; Sakurai, K; Tari, A1
Kanatsu, K; Kato, S; Mizoguchi, H; Ogawa, Y; Takeuchi, K; Tanaka, A1
Arakawa, T; Fujiwara, Y; Hamaguchi, M; Higuchi, K; Matsumoto, T; Oshitani, N; Sasaki, E; Shiba, M; Takashima, T; Tanigawa, T; Tominaga, K; Watanabe, T1
Fujimori, S; Futagami, S; Gudis, K; Hiratsuka, T; Kusunoki, M; Miyake, K; Nishigaki, H; Sakamoto, C; Shinji, Y; Shinoki, K; Suzuki, K; Tatsuguchi, A; Tsukui, T; Wada, K1
Osaka, T; Sakurai, K; Yamasaki, K1
Ichikawa, H; Isozaki, Y; Katada, K; Naito, Y; Okanoue, T; Tomatsuri, N; Yoshida, N; Yoshikawa, T1

Trials

1 trial(s) available for opc 12759 and mocetinostat

ArticleYear
Rebamipide protects against indomethacin-induced gastric mucosal injury in healthy volunteers in a double-blind, placebo-controlled study.
    Digestive diseases and sciences, 1998, Volume: 43, Issue:9 Suppl

    Topics: Adult; Alanine; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Antioxidants; Cytokines; Double-Blind Method; Gastric Mucosa; Humans; Indomethacin; Lipid Peroxidation; Male; Peroxidase; Quinolones; Reference Values; Stomach Ulcer; Treatment Outcome

1998

Other Studies

13 other study(ies) available for opc 12759 and mocetinostat

ArticleYear
Preventive effect of rebamipide on gastric lesions induced by ischemia-reperfusion in the rat.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 275, Issue:1

    Topics: Alanine; Animals; Anti-Ulcer Agents; Chemotaxis, Leukocyte; Free Radical Scavengers; Gastric Mucosa; Hydroxyl Radical; Male; Malondialdehyde; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitric Oxide Synthase; Peroxidase; Quinolones; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Stimulation, Chemical; Stomach; Stomach Ulcer; Superoxide Dismutase; Superoxides; Zymosan

1995
Rebamipide attenuates indomethacin-induced gastric mucosal lesion formation by inhibiting activation of leukocytes in rats.
    Digestive diseases and sciences, 1997, Volume: 42, Issue:2

    Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Cimetidine; Gastric Mucosa; Glycine; Humans; In Vitro Techniques; Indomethacin; Leukocyte Elastase; Male; Neutrophil Activation; Neutrophils; Peroxidase; Quinolones; Rats; Rats, Wistar; Serine Proteinase Inhibitors; Sulfonamides

1997
Effects of rebamipide, a novel anti-ulcer agent, on gastric mucosal injury induced by platelet-activating factor in rats.
    Digestive diseases and sciences, 1997, Volume: 42, Issue:12

    Topics: Alanine; Animals; Anti-Ulcer Agents; Gastric Mucosa; Lipid Peroxides; Male; Peroxidase; Platelet Activating Factor; Quinolones; Rats; Rats, Wistar

1997
Rebamipide prevents indomethacin-induced gastric mucosal lesion formation by inhibiting activation of neutrophils in rats.
    Digestive diseases and sciences, 1998, Volume: 43, Issue:9 Suppl

    Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Calcium; Gastric Mucosa; Indomethacin; Leukocyte Elastase; Male; Neutrophils; Peroxidase; Quinolones; Rats; Rats, Wistar; Stomach Ulcer

1998
Changes in colonic inflammation induced by dextran sulfate sodium (DSS) during short- and long-term administration of rebamipide.
    Digestive diseases and sciences, 1998, Volume: 43, Issue:9 Suppl

    Topics: Acute Disease; Alanine; Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Anticoagulants; Chronic Disease; Colitis; Colonoscopy; Dextran Sulfate; Drug Administration Schedule; Leukocyte Count; Male; Peroxidase; Quinolones; Rats; Rats, Sprague-Dawley

1998
Effect of rebamipide on liver damage and increased tumor necrosis factor in a rat model of endotoxin shock.
    Digestive diseases and sciences, 1998, Volume: 43, Issue:9 Suppl

    Topics: Alanine; Animals; Disease Models, Animal; Enzyme Inhibitors; Escherichia coli; Lipopolysaccharides; Liver; Male; Peroxidase; Quinolones; Rats; Rats, Sprague-Dawley; Shock, Septic; Tumor Necrosis Factor-alpha

1998
Indomethacin-induced gastric antral damage in hamsters: are neutrophils involved?
    Alimentary pharmacology & therapeutics, 1999, Volume: 13, Issue:2

    Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cricetinae; Gastric Mucosa; Indomethacin; Male; Mesocricetus; Methotrexate; Mice; Neutrophils; Peroxidase; Pyloric Antrum; Quinolones

1999
Rebamipide, an antiulcer drug, prevents DSS-induced colitis formation in rats.
    Digestive diseases and sciences, 2000, Volume: 45, Issue:8

    Topics: Alanine; Animals; Anti-Ulcer Agents; Colitis; Colon; Dextran Sulfate; Disease Models, Animal; Interleukin-1; Interleukin-8; Male; Peroxidase; Quinolones; Rats; Rats, Wistar

2000
Protective effect of rebamipide on indomethacin-induced intestinal damage in rats.
    Journal of gastroenterology and hepatology, 2001, Volume: 16, Issue:10

    Topics: Alanine; Ampicillin; Animals; Anti-Ulcer Agents; Bacterial Translocation; Catalase; Dose-Response Relationship, Drug; Enterobacteriaceae; Enzyme Inhibitors; Indomethacin; Intestinal Diseases; Lipid Peroxidation; Male; Nitric Oxide Synthase; Peroxidase; Quinolones; Rats; Rats, Sprague-Dawley; Superoxide Dismutase

2001
Comparison of the effects of rebamipide with those of cimetidine on chronic gastritis associated with Helicobacter pylori in Mongolian gerbils.
    Alimentary pharmacology & therapeutics, 2003, Volume: 18 Suppl 1

    Topics: Alanine; Animals; Anti-Ulcer Agents; Chemokines; Cimetidine; Gastrins; Gastritis; Gerbillinae; Helicobacter Infections; Helicobacter pylori; Male; Neutrophils; Peroxidase; Quinolones; Tumor Necrosis Factor-alpha

2003
COX-1 and COX-2 conversely promote and suppress ischemia-reperfusion gastric injury in mice.
    Scandinavian journal of gastroenterology, 2005, Volume: 40, Issue:8

    Topics: Alanine; Animals; Blotting, Western; Celiac Artery; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Gastric Mucosa; Intercellular Adhesion Molecule-1; Laser-Doppler Flowmetry; Ligation; Membrane Proteins; Mice; Mice, Inbred ICR; Nitrobenzenes; Peroxidase; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Quinolones; Regional Blood Flow; Reperfusion Injury; Sulfonamides; Thiobarbituric Acid Reactive Substances

2005
Rebamipide reduces recurrence of experimental gastric ulcers: role of free radicals and neutrophils.
    Digestive diseases and sciences, 2005, Volume: 50 Suppl 1

    Topics: Acetic Acid; Alanine; Animals; Anti-Ulcer Agents; Free Radicals; Gastric Mucosa; Glutathione Peroxidase; Indicators and Reagents; Inflammation; Lipid Peroxidation; Neutrophil Infiltration; Peroxidase; Quinolones; Rats; Recurrence; Stomach Ulcer; Superoxide Dismutase

2005
Prevention by rebamipide of acute reflux esophagitis in rats.
    Digestive diseases and sciences, 2005, Volume: 50 Suppl 1

    Topics: Acute Disease; Alanine; Animals; Anti-Ulcer Agents; Chemokine CXCL1; Chemokines, CXC; Esophagitis, Peptic; Esophagus; Intercellular Signaling Peptides and Proteins; Lipid Peroxidation; Male; Mucous Membrane; Neutrophil Activation; Peroxidase; Quinolones; Rats; Rats, Wistar; RNA, Messenger; Tumor Necrosis Factor-alpha

2005