opc 12759 has been researched along with dinoprostone in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.88) | 18.7374 |
| 1990's | 1 (5.88) | 18.2507 |
| 2000's | 8 (47.06) | 29.6817 |
| 2010's | 7 (41.18) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chijiwa, T; Ishiyama, H; Kanbe, T; Morita, S; Yamasaki, K | 1 |
| Kleine, A; Kluge, S; Peskar, BM | 1 |
| Adachi, K; Fukuda, R; Ishihara, S; Kazumori, H; Kinoshita, Y; Moriyama, N; Suetsugu, H; Watanabe, M | 1 |
| Gunawan, ES; Hori, M; Iijima, H; Kakiuchi, Y; Kawai, N; Kawano, S; Kimura, A; Okuda, Y; Sasaki, Y; Sun, WH; Tsuji, S; Tsujii, M; Yasumaru, M | 1 |
| Jung, HC; Kim, JM; Kim, JS; Song, IS | 1 |
| Kataoka, S; Kuwayama, H; Soma, R; Takada, H; Takagi, K; Takahashi, M | 1 |
| Alexander, JS; Itoh, M; Joh, T; Nomura, T; Ohara, H; Oshima, T; Sasaki, M; Seno, K; Takezono, Y; Yokoyama, Y | 1 |
| Chen, J; Du, Y; Fang, D; Gao, J; Gong, Y; Guo, X; He, L; Jiang, B; Li, Y; Li, Z; Ren, J; Shi, R; Tian, Z; Wu, J; Zhan, X; Zhang, Z | 1 |
| Fuchikami, J; Takahashi, M; Takeuchi, Y | 1 |
| Haixia, C; Jie, L; Qi, Z; Xiaoying, Z | 1 |
| Bullins, KW; Denham, JW; Hanley, AV; Hanley, GA; Harirforoosh, S; Panus, PC; Wood, RC; Wyatt, JE | 1 |
| Chen, QK; Lai, Y; Li, JY; Ouyang, H; Shan, TD; Xia, ZS; Yang, HS; Yu, T; Zhong, W | 1 |
| Nakamura, K; Nakamura, M; Onikubo, T; Shinohara, A | 1 |
| El-Sisi, A; Zakaria, S | 1 |
| Carvalhaes, A; De Nucci, G; Gagliano-Jucá, T; Magalhães, AF; Moreno, RA; Napolitano, M; Trevisan, MS; Wallace, JL; Zaminelli, T | 1 |
| Jeong, S; Jung, Y; Kim, BJ; Kim, D; Kim, W; Lee, S; Min, DS; Yang, Y; Yoon, JH | 1 |
2 trial(s) available for opc 12759 and dinoprostone
| Article | Year |
|---|---|
Anti-inflammatory effects of rebamipide according to Helicobacter pylori status in patients with chronic erosive gastritis: a randomized sucralfate-controlled multicenter trial in China-STARS study.
Topics: Adult; Alanine; Anti-Inflammatory Agents; Anti-Ulcer Agents; China; Dinoprostone; Female; Gastric Mucosa; Gastritis; Helicobacter Infections; Helicobacter pylori; Humans; Male; Malondialdehyde; Middle Aged; Quinolones; Sucralfate | 2008 |
Rebamipide does not protect against naproxen-induced gastric damage: a randomized double-blind controlled trial.
Topics: Adolescent; Adult; Alanine; Anti-Inflammatory Agents, Non-Steroidal; Dinoprostone; Double-Blind Method; Female; Gastric Mucosa; Gastrointestinal Agents; Humans; Male; Middle Aged; Naproxen; Quinolones; Stomach Diseases; Young Adult | 2016 |
15 other study(ies) available for opc 12759 and dinoprostone
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Gastric mucosal protection by OPC-12759, a novel antiulcer compound, in the rat.
Topics: Alanine; Animals; Anti-Ulcer Agents; Atropine; Cimetidine; Dinoprostone; Gastric Mucosa; Indomethacin; Injections, Intraperitoneal; Male; Prostaglandins E; Quinolines; Quinolones; Rats; Rats, Inbred Strains | 1987 |
Stimulation of prostaglandin biosynthesis mediates gastroprotective effect of rebamipide in rats.
Topics: 6-Ketoprostaglandin F1 alpha; Alanine; Animals; Anti-Ulcer Agents; Dinoprostone; Dose-Response Relationship, Drug; Gastric Juice; In Vitro Techniques; Indomethacin; Male; Prostaglandins; Quinolones; Rats; Rats, Wistar; Thromboxane B2 | 1993 |
Effect of rebamipide on prostaglandin EP4 receptor gene expression in rat gastric mucosa.
Topics: Alanine; Animals; Anti-Ulcer Agents; Cyclic AMP; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Gastric Mucosa; Gene Expression; Isoenzymes; Male; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Quinolones; Rats; Rats, Wistar; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP4 Subtype; RNA, Messenger | 2000 |
Induction of cyclooxygenase-2 in rat gastric mucosa by rebamipide, a mucoprotective agent.
Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Drug Interactions; Enzyme Induction; Enzyme Inhibitors; Gastric Mucosa; Hydrochloric Acid; Isoenzymes; Male; Membrane Proteins; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Quinolones; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Sulfonamides; Up-Regulation | 2000 |
The effect of rebamipide on the expression of proinflammatory mediators and apoptosis in human neutrophils by Helicobacter pylori water-soluble surface proteins.
Topics: Alanine; Anti-Ulcer Agents; Apoptosis; Blotting, Western; Caspase 3; Caspases; Cyclooxygenase 2; Dinoprostone; Enzyme-Linked Immunosorbent Assay; Helicobacter pylori; Humans; Isoenzymes; Membrane Proteins; Mitogen-Activated Protein Kinase Kinases; Neutrophils; NF-kappa B; Prostaglandin-Endoperoxide Synthases; Quinolones; Radioimmunoassay; RNA, Messenger; Up-Regulation | 2003 |
Gastric restitution is inhibited by dexamethasone, which is reversed by hepatocyte growth factor and rebamipide.
Topics: Alanine; Anti-Inflammatory Agents; Anti-Ulcer Agents; Cells, Cultured; Cyclooxygenase 2; Dexamethasone; Dinoprostone; Fibroblasts; Gastric Mucosa; Hepatocyte Growth Factor; Humans; Isoenzymes; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Quinolones; RNA, Messenger | 2003 |
The protective effect of rebamipide on paracellular permeability of rat gastric epithelial cells.
Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Cyclooxygenase Inhibitors; Dinoprostone; Epithelial Cells; Gastric Mucosa; Indomethacin; Nitrobenzenes; Permeability; Quinolones; Rats; Sulfonamides | 2003 |
Vulnerability of gastric mucosa to prednisolone in rats chronically exposed to cigarette smoke.
Topics: Alanine; Animals; Anti-Ulcer Agents; Blood Gas Analysis; Dinoprostone; Disease Models, Animal; Gastric Mucosa; Hypoxia-Inducible Factor 1, alpha Subunit; Lipid Peroxides; Male; Peptic Ulcer Hemorrhage; Prednisolone; Pulmonary Disease, Chronic Obstructive; Quinolones; Rats; Rats, Wistar; Respiratory Function Tests; Respiratory System; Smoking; Stomach Ulcer; Vascular Endothelial Growth Factor A | 2008 |
Effect of rebamipide on quality of peptic ulcer healing in rat.
Topics: Alanine; Animals; Anti-Ulcer Agents; Dinoprostone; Drug Therapy, Combination; Gastric Mucosa; Interleukin-8; Male; Omeprazole; Peptic Ulcer; Proton Pump Inhibitors; Quinolones; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Stomach; Ultrasonography | 2009 |
Effects of rebamipide on nephrotoxicity associated with selected NSAIDs in rats.
Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Celecoxib; Cell Adhesion Molecules; Creatinine; Diclofenac; Dinoprostone; Drug Interactions; Kidney; Kidney Diseases; Male; Nitric Oxide; Potassium; Pyrazoles; Quinolones; Rats; Rats, Sprague-Dawley; Sodium; Sulfonamides | 2013 |
Rebamipide Promotes the Regeneration of Aspirin-Induced Small-Intestine Mucosal Injury through Accumulation of β-Catenin.
Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; beta Catenin; Body Weight; Cell Division; Cyclooxygenase 2; Dinoprostone; Female; Intestinal Absorption; Intestinal Mucosa; Jejunum; Male; Membrane Proteins; Mice; Mice, Inbred BALB C; Permeability; Proto-Oncogene Proteins c-myc; Quinolones; Random Allocation; Regeneration; RNA, Messenger; Tight Junctions | 2015 |
[Efficacy of Rebamipide Gargle against Chemotherapy-induced Oral Mucositis].
Topics: Adult; Aged; Aged, 80 and over; Alanine; Antineoplastic Agents; Antioxidants; Dinoprostone; Epoprostenol; Female; Gastric Mucosa; Humans; Male; Middle Aged; Mouthwashes; Quality of Life; Quinolones; Solutions; Stomatitis; Treatment Outcome | 2015 |
Rebamipide retards CCl4-induced hepatic fibrosis in rats: Possible role for PGE2.
Topics: Alanine; Alanine Transaminase; Animals; Anti-Inflammatory Agents; Aspartate Aminotransferases; Carbon Tetrachloride; Collagen; Dinoprostone; Disease Models, Animal; Fibrosis; Humans; Interleukin-10; Liver; Liver Cirrhosis; Male; Oxidative Stress; Quinolones; Rats, Wistar; Up-Regulation | 2016 |
Rebamipide induces the gastric mucosal protective factor, cyclooxygenase-2, via activation of 5'-AMP-activated protein kinase.
Topics: Alanine; AMP-Activated Protein Kinases; Animals; Anti-Ulcer Agents; Cyclooxygenase 2; Dinoprostone; Enzyme Activation; Gastric Mucosa; Male; Mice, Inbred ICR; Quinolones; Stomach Ulcer | 2017 |