opc 12759 has been researched along with aspirin in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 11 (84.62) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Handa, O; Ichikawa, H; Isozaki, Y; Kajikawa, H; Kokura, S; Matsui, H; Naito, Y; Nakabe, N; Suzuki, T; Takagi, T; Yoshida, N; Yoshikawa, T | 1 |
| Goto, S; Kawai, T; Yamagishi, T | 1 |
| Asaka, M; Kamada, G; Kato, M; Nishida, M; Nishida, U; Ono, S; Shimizu, Y; Yoshida, T | 1 |
| Abe, T; Fujioka, T; Inoue, K; Kodama, M; Mizukami, K; Murakami, K; Okimoto, T; Uchida, M | 1 |
| Fujita, T; Kato, M; Katsuki, S; Kurokawa, S; Nishikawa, K; Ohira, K; Ohta, H; Saitoh, Y; Sato, Y; Yamada, M | 1 |
| Fukui, H; Hida, N; Hori, K; Miwa, H; Nakamura, S; Ogawa, T; Ohda, Y; Okugawa, T; Oshima, T; Tomita, T; Tozawa, K; Watari, J | 1 |
| Furuta, T; Sugimoto, M; Uotani, T | 1 |
| Amagase, K; Hashimoto, E; Itayama, M; Izuhara, C; Takayama, S; Takeuchi, K | 1 |
| Arakawa, T; Fujimoto, K; Handa, O; Higuchi, K; Naito, Y; Sakata, Y; Shiba, M; Takeuchi, T; Tanigawa, T; Watanabe, T; Yoshikawa, T | 1 |
| Chen, QK; Lai, Y; Li, JY; Ouyang, H; Shan, TD; Xia, ZS; Yang, HS; Yu, T; Zhong, W | 1 |
| Dohi, O; Fukui, A; Handa, O; Higashimura, Y; Ishikawa, T; Itoh, Y; Kamada, K; Katada, K; Konishi, H; Majima, A; Mukai, R; Naito, Y; Okayama, T; Suyama, Y; Takagi, T; Takayama, S; Uchiyama, K; Ushiroda, C; Yasuda-Onozawa, Y; Yoshida, N | 1 |
| Chaitongrat, S; Lertsuwunseri, V; Mahachai, V; Pittayanon, R; Piyachaturawat, P; Prueksapanich, P; Rerknimitr, R; Srimahachota, S | 1 |
7 trial(s) available for opc 12759 and aspirin
| Article | Year |
|---|---|
Circadian variations of gastrointestinal mucosal damage detected with transnasal endoscopy in apparently healthy subjects treated with low-dose aspirin (ASA) for a short period.
Topics: Adult; Alanine; Aspirin; Circadian Rhythm; Double-Blind Method; Endoscopy; Female; Gastric Mucosa; Humans; Intestinal Mucosa; Male; Quinolones; Time Factors; Treatment Outcome; Ulcer; Young Adult | 2009 |
Evaluation of small bowel blood flow in healthy subjects receiving low-dose aspirin.
Topics: Adult; Alanine; Anti-Ulcer Agents; Area Under Curve; Aspirin; Blood Flow Velocity; Contrast Media; Cross-Over Studies; Double-Blind Method; Endoscopy; Humans; Intestine, Small; Male; Placebos; Quinolones; Treatment Outcome; Ultrasonography | 2011 |
Aspirin-induced small bowel injuries and the preventive effect of rebamipide.
Topics: Adult; Aged; Alanine; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Capsule Endoscopy; Cross-Over Studies; Double-Blind Method; Humans; Intestinal Diseases; Intestinal Mucosa; Intestine, Small; Male; Middle Aged; Omeprazole; Placebos; Quinolones; Young Adult | 2011 |
A randomized, double-blinded, placebo-controlled, multicenter trial, healing effect of rebamipide in patients with low-dose aspirin and/or non-steroidal anti-inflammatory drug induced small bowel injury.
Topics: Aged; Alanine; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Capsule Endoscopy; Dietary Proteins; Double-Blind Method; Female; Humans; Intestinal Diseases; Intestinal Mucosa; Intestine, Small; Male; Middle Aged; Quinolones; Wound Healing | 2014 |
A randomized, double-blind, placebo-controlled study of rebamipide for gastric mucosal injury taking aspirin with or without clopidogrel.
Topics: Adult; Alanine; Anti-Ulcer Agents; Aspirin; Clopidogrel; Double-Blind Method; Gastric Mucosa; Gastrointestinal Hemorrhage; Healthy Volunteers; Humans; Male; Peptic Ulcer; Platelet Aggregation Inhibitors; Quinolones; Ticlopidine; Young Adult | 2014 |
A multicenter, randomized, double-blind, placebo-controlled trial of high-dose rebamipide treatment for low-dose aspirin-induced moderate-to-severe small intestinal damage.
Topics: Aged; Alanine; Anti-Ulcer Agents; Aspirin; Capsule Endoscopy; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Humans; Intestinal Diseases; Intestine, Small; Male; Quinolones; Severity of Illness Index; Treatment Outcome | 2015 |
Cytoprotective agent for peptic ulcer prevention in patients taking dual antiplatelet agents: A randomized, double-blind placebo-controlled trial.
Topics: Aged; Alanine; Anti-Ulcer Agents; Aspirin; Cilostazol; Clopidogrel; Cytoprotection; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Peptic Ulcer; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Quinolones; Thailand; Ticagrelor; Time Factors; Treatment Outcome | 2019 |
6 other study(ies) available for opc 12759 and aspirin
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Prophylactic effect of rebamipide on aspirin-induced gastric lesions and disruption of tight junctional protein zonula occludens-1 distribution.
Topics: Alanine; Animals; Anti-Ulcer Agents; Aspirin; Cell Line; Cytoprotection; Fluorescent Antibody Technique; Gastric Mucosa; Male; Membrane Proteins; Permeability; Phosphoproteins; Quinolones; Rats; Rats, Sprague-Dawley; Zonula Occludens-1 Protein | 2008 |
Does rebamipide prevent gastric mucosal injury in patients taking aspirin and clopidogrel?
Topics: Alanine; Anti-Ulcer Agents; Aspirin; Clopidogrel; Gastrointestinal Hemorrhage; Humans; Male; Platelet Aggregation Inhibitors; Quinolones; Ticlopidine | 2014 |
Effect of rebamipide on gastric bleeding and ulcerogenic responses induced by aspirin plus clopidogrel under stimulation of acid secretion in rats.
Topics: Alanine; Animals; Anti-Ulcer Agents; Aspirin; Clopidogrel; Disease Models, Animal; Gastric Acid; Gastric Mucosa; Gastrointestinal Hemorrhage; Male; Platelet Aggregation Inhibitors; Quinolones; Rats, Sprague-Dawley; Stomach Ulcer; Ticlopidine; Treatment Outcome | 2014 |
Rebamipide Promotes the Regeneration of Aspirin-Induced Small-Intestine Mucosal Injury through Accumulation of β-Catenin.
Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; beta Catenin; Body Weight; Cell Division; Cyclooxygenase 2; Dinoprostone; Female; Intestinal Absorption; Intestinal Mucosa; Jejunum; Male; Membrane Proteins; Mice; Mice, Inbred BALB C; Permeability; Proto-Oncogene Proteins c-myc; Quinolones; Random Allocation; Regeneration; RNA, Messenger; Tight Junctions | 2015 |
Mucus reduction promotes acetyl salicylic acid-induced small intestinal mucosal injury in rats.
Topics: Alanine; Animals; Aspirin; Intestinal Mucosa; Intestine, Small; Male; Mucus; Polysorbates; Protective Agents; Quinolones; Rats, Sprague-Dawley | 2018 |