Page last updated: 2024-09-03

ono 3307 and gabexate

ono 3307 has been researched along with gabexate in 3 studies

Compound Research Comparison

Studies
(ono 3307)
Trials
(ono 3307)
Recent Studies (post-2010)
(ono 3307)
Studies
(gabexate)
Trials
(gabexate)
Recent Studies (post-2010) (gabexate)
120174353106

Protein Interaction Comparison

ProteinTaxonomyono 3307 (IC50)gabexate (IC50)
Solute carrier family 22 member 2Homo sapiens (human)0.9
Coagulation factor XHomo sapiens (human)4.61
PlasminogenHomo sapiens (human)0.431
Urokinase-type plasminogen activatorHomo sapiens (human)0.431
Serine protease hepsinHomo sapiens (human)0.383
Multidrug and toxin extrusion protein 1Homo sapiens (human)0.5

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Pilgram, O; Steinmetzer, T; Wenzel, BM; Wiedemeyer, SJA1
Hirano, T; Manabe, T; Tobe, T1
Futagami, M; Imaki, K; Kawasaki, A; Matsuoka, S; Ohno, H; Okegawa, T1

Other Studies

3 other study(ies) available for ono 3307 and gabexate

ArticleYear
Fibrinolysis Inhibitors: Potential Drugs for the Treatment and Prevention of Bleeding.
    Journal of medicinal chemistry, 2020, 02-27, Volume: 63, Issue:4

    Topics: Animals; Antifibrinolytic Agents; Catalytic Domain; Crystallography, X-Ray; Fibrinolysin; Fibrinolysis; Hemorrhage; Humans; Ligands; Molecular Structure; Plasminogen; Protein Binding; Protein Domains

2020
Protection by a new synthetic protease inhibitor, ONO3307, of the rat exocrine pancreas during acute edematous pancreatitis induced by a supramaximal dose of caerulein in comparison with FOY007.
    Pharmacology, 1992, Volume: 45, Issue:2

    Topics: Acute Disease; Amylases; Animals; Body Water; Cathepsin B; Ceruletide; Edema; Gabexate; Guanidines; L-Lactate Dehydrogenase; Lysosomes; Male; Pancreas; Pancreatitis; Rats; Rats, Inbred Strains; Serine Proteinase Inhibitors

1992
Inhibitory effects of ONO-3307 on various proteases and tissue thromboplastin in vitro and on experimental thrombosis in vivo.
    Japanese journal of pharmacology, 1989, Volume: 51, Issue:4

    Topics: Animals; Benzamidines; Dialysis; Endotoxins; Fibrinolytic Agents; Gabexate; Guanidines; Humans; In Vitro Techniques; Indicators and Reagents; Kinetics; Leukocytes; Male; N-Formylmethionine Leucyl-Phenylalanine; Pancreatic Elastase; Rats; Rats, Inbred Strains; Serine Proteinase Inhibitors; Thromboplastin

1989