ono 1078 has been researched along with thromboxane a2 in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (14.29) | 18.7374 |
| 1990's | 7 (50.00) | 18.2507 |
| 2000's | 5 (35.71) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Adachi, M; Kobayashi, H; Misawa, M; Okazawa, A; Takahashi, T | 1 |
| Arai, Y; Urata, Y | 1 |
| Hashimoto, H; Hieda, N; Ito, T; Ogawa, K; Okumura, K; Satake, T; Toki, Y | 1 |
| Hashimoto, H; Hieda, N; Ito, T; Ito, Y; Ogawa, K; Okumura, K; Satake, T; Toki, Y; Torii, T | 1 |
| Bochnowicz, S; Underwood, DC | 1 |
| Iwama, T; Nagai, H; Sakurai, T; Yamaguchi, S | 1 |
| Arakida, Y; Honda, K; Miyata, K; Ohga, K; Suwa, K; Yamada, T; Yokota, M | 1 |
| Kohno, S; Nabe, T; Tomioka, H; Yamashita, K | 1 |
| Abo, M; Fujimura, M; Hashimoto, T; Ishiura, Y; Kamio, Y; Matsuda, T; Myou, S | 1 |
| Ashida, Y; Kohno, S; Matsumoto, T; Mizutani, N; Nabe, T; Sasaki, K; Yamasaki, M | 1 |
| Ashida, Y; Kohno, S; Matsumoto, T; Mizutani, N; Nabe, T; Sakura, Y; Sasaki, K; Yamasaki, ML | 1 |
| Kohno, S; Mizutani, N; Nabe, T; Nakanishi, Y; Takenaka, H | 1 |
| Jiang, S; Kamei, C; Kishi, Y; Nakano, Y; Yatsuzuka, R | 1 |
| Iwasaki, H; Kato, T; Miyagawa, N; Shibata, T; Tanaka, M; Wakitani, K | 1 |
2 trial(s) available for ono 1078 and thromboxane a2
| Article | Year |
|---|---|
[Aspects of new drug development].
Topics: Chromones; Clinical Trials as Topic; Drug Design; Humans; Imidazoles; Leukotriene Antagonists; Prostaglandins; Thromboxane A2; Thromboxane-A Synthase | 1990 |
Effect of leukotriene and thromboxane antagonist on propranolol-induced bronchoconstriction.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Asthma; Benzoquinones; Bronchoconstriction; Chromones; Double-Blind Method; Female; Forced Expiratory Volume; Heptanoic Acids; Humans; Leukotriene Antagonists; Male; Middle Aged; Propranolol; Thromboxane A2; Vital Capacity | 1999 |
12 other study(ies) available for ono 1078 and thromboxane a2
| Article | Year |
|---|---|
[The effect of leukotriene C4/D4 receptor antagonist (ONO-1078) and thromboxane A2 synthetase inhibitor (OKY-046) on airway hyperresponsiveness induced by ozone exposure in guinea pigs].
Topics: Acrylates; Administration, Inhalation; Animals; Bronchi; Bronchoalveolar Lavage Fluid; Chromones; Guinea Pigs; Methacholine Chloride; Methacholine Compounds; Methacrylates; Muscle Contraction; Ozone; Receptors, Immunologic; Receptors, Leukotriene; Thromboxane A2 | 1990 |
Protective effects of a thromboxane synthetase inhibitor, a thromboxane antagonist, a lipoxygenase inhibitor and a leukotriene C4, D4 antagonist on myocardial injury caused by acute myocardial infarction in the canine heart.
Topics: Animals; Arrhythmias, Cardiac; Benzoquinones; Cardiomyopathies; Chromones; Coronary Disease; Dogs; Hemorrhage; Lipoxygenase Inhibitors; Male; Myocardial Infarction; Myocardium; Neutrophils; Quinones; SRS-A; Thiophenes; Thromboxane A2; Thromboxane-A Synthase | 1989 |
Effects of a new thromboxane A2-antagonist (ONO-3708) and a new leukotriene-antagonist (ONO-1078) on thromboxane A2 analogue-, leukotriene C4-, and D4-induced regional myocardial blood flow reduction.
Topics: Animals; Blood Flow Velocity; Chromones; Coronary Circulation; Coronary Disease; Dogs; Male; Methacrylates; SRS-A; Thromboxane A2; Thromboxane-A Synthase | 1988 |
Dose-dependent mediation of leukotriene D4-induced airway microvascular leakage and bronchoconstriction in the guinea pig.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Bridged Bicyclo Compounds, Heterocyclic; Bronchi; Bronchoconstriction; Capillary Permeability; Chromones; Fatty Acids, Unsaturated; Furans; Guinea Pigs; Hydrazines; Hydroxyurea; Leukotriene D4; Lipoxygenase Inhibitors; Lung; Male; Meclofenamic Acid; Plasma; Prostaglandin Endoperoxides, Synthetic; Pyrilamine; Receptors, Thromboxane; SRS-A; Thromboxane A2; Trachea; Vasoconstrictor Agents | 1995 |
Pharmacological studies of platelet-activating factor (PAF)-induced augmentation of response to histamine in guinea-pigs.
Topics: Animals; Benzoquinones; Bridged Bicyclo Compounds; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Capillary Permeability; Chromones; Drug Interactions; Fatty Acids, Monounsaturated; Guinea Pigs; Histamine; Indomethacin; Leukocyte Count; Leukotriene Antagonists; Lipoxygenase Inhibitors; Male; Methacrylates; Phospholipid Ethers; Platelet Activating Factor; Pressure; Respiratory Physiological Phenomena; Respiratory System; Thromboxane A2 | 1994 |
Effects of lipid mediator antagonists on predominant mediator-controlled asthmatic reactions in passively sensitized guinea pigs.
Topics: Administration, Oral; Animals; Asthma; Chromones; Disease Models, Animal; Guinea Pigs; Immunization, Passive; Leukotriene Antagonists; Leukotrienes; Male; Membrane Proteins; Phenylacetates; Receptors, Leukotriene; Receptors, Thromboxane; Serum Albumin, Bovine; Sulfonamides; Tetrazoles; Thiazoles; Thromboxane A2; Thromboxane B2 | 1999 |
Repeated antigen inhalations alter chemical mediators that cause asthmatic obstruction in guinea pigs.
Topics: Administration, Inhalation; Airway Obstruction; Aluminum Hydroxide; Animals; Antigens; Asthma; Benzoquinones; Chromones; Eosinophilia; Guinea Pigs; Heptanoic Acids; Histamine H1 Antagonists; Leukotriene Antagonists; Lung; Male; Ovalbumin; Prostaglandin Antagonists; Pyrilamine; Thromboxane A2 | 1999 |
Involvement of thromboxane A2 and peptide leukotrienes in early and late phase nasal blockage in a guinea pig model of allergic rhinitis.
Topics: Animals; Anti-Allergic Agents; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Benzoquinones; Chromones; Dexamethasone; Guinea Pigs; Heptanoic Acids; Histamine; Histamine Release; Leukotrienes; Male; Nasal Cavity; Nasal Obstruction; Rhinitis, Allergic, Seasonal; Sneezing; Terfenadine; Therapeutic Irrigation; Thromboxane A2 | 2001 |
Pharmacological characterization of the leukocyte kinetics after intranasal antigen challenge in a guinea pig model of allergic rhinitis.
Topics: Administration, Intranasal; Animals; Anti-Allergic Agents; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Antigens; Benzoquinones; Chromones; Dexamethasone; Guinea Pigs; Heptanoic Acids; Kinetics; Leukocyte Count; Leukocytes; Leukotriene Antagonists; Male; Nasal Cavity; Rhinitis, Allergic, Seasonal; Terfenadine; Therapeutic Irrigation; Thromboxane A2 | 2001 |
Synergism between cysteinyl leukotrienes and thromboxane A2 to induce allergic late phase nasal blockage in guinea pigs.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Benzoquinones; Chromones; Guinea Pigs; Heptanoic Acids; Hypersensitivity; Leukotriene D4; Leukotrienes; Male; Nasal Cavity; Thromboxane A2 | 2004 |
Participation in cysteinyl leukotrienes and thromboxane A2 in nasal congestion model in Brown Norway rats.
Topics: Animals; Benzoquinones; Carbazoles; Chromones; Dose-Response Relationship, Drug; Heptanoic Acids; Indoles; Leukotrienes; Male; Membrane Proteins; Phenylcarbamates; Rats; Rats, Inbred BN; Receptors, Leukotriene; Receptors, Thromboxane A2, Prostaglandin H2; Rhinitis; Sneezing; Sulfonamides; Thromboxane A2; Tosyl Compounds | 2007 |
Two pharmacological phases in antigen-induced immediate airway response in rats.
Topics: Administration, Inhalation; Adrenergic alpha-2 Receptor Agonists; Adrenergic beta-Agonists; Albuterol; Animals; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Antigens; Benzoquinones; Bronchial Hyperreactivity; Chromones; Heptanoic Acids; Histamine H2 Antagonists; Hypersensitivity, Immediate; Ketotifen; Leukotriene Antagonists; Male; Ovalbumin; p-Methoxy-N-methylphenethylamine; Prednisolone; Rats; Rats, Sprague-Dawley; Thromboxane A2 | 2008 |