Page last updated: 2024-08-16

ono 1078 and ozagrel

ono 1078 has been researched along with ozagrel in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19901 (6.67)18.7374
1990's13 (86.67)18.2507
2000's1 (6.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Furukawa, K; Hikasa, Y; Hori, K; Nishikawa, M; Shimoyama, T; Tanida, N; Yamada, K1
Fujii, E; Nomoto, T1
Ikeda, S; Kawasaki, A; Nambu, F; Okegawa, T; Omawari, N; Sawada, M; Yube, N1
Makino, S1
Adachi, M; Kobayashi, H; Misawa, M; Okazawa, A; Takahashi, T1
Hashimoto, H; Hieda, N; Ito, T; Ito, Y; Ogawa, K; Okumura, K; Satake, T; Toki, Y; Torii, T1
Hikasa, Y; Hori, K; Nishikawa, M; Shimoyama, T; Tanida, N1
Iwama, T; Nagai, H; Sakurai, T; Yamaguchi, S1
Aishita, H; Nakagawa, N; Obata, T; Okada, Y; Terawaki, T1
Misawa, M; Sugiyama, Y1
Iwahisa, Y; Kagoshima, M; Kawakami, Y; Terasawa, M; Tomomatsu, N; Yamaguchi, S1
Iwahisa, Y; Kagoshima, M; Kawakami, Y; Matsuura, M; Terasawa, M; Tomomatsu, N; Yamaguchi, S1
Fukuchi, Y; Ishii, S; Katayama, H; Nagase, T; Ouchi, Y; Shimizu, T1
Asai, S; Kohno, S; Matsuo, N; Matsuse, H; Obase, Y; Shimoda, T1
Asanuma, T; Ishibashi, Y; Katoh, H; Murakami, Y; Ohta, Y; Sano, K; Shimada, T; Shimizu, H; Takahashi, N1

Trials

1 trial(s) available for ono 1078 and ozagrel

ArticleYear
Effects of cysteinyl-leukotriene receptor antagonist, thromboxane A2 receptor antagonist, and thromboxane A2 synthetase inhibitor on antigen-induced bronchoconstriction in patients with asthma.
    Chest, 1998, Volume: 114, Issue:4

    Topics: Administration, Oral; Adult; Anti-Asthmatic Agents; Antigens; Asthma; Benzoquinones; Blood Proteins; Bronchial Provocation Tests; Bronchoconstriction; Chromones; Cross-Over Studies; Eosinophil Granule Proteins; Female; Follow-Up Studies; Heptanoic Acids; Histamine; Humans; Leukotriene Antagonists; Male; Membrane Proteins; Methacrylates; Receptors, Leukotriene; Receptors, Thromboxane; Ribonucleases; Thromboxane B2; Thromboxane-A Synthase; Treatment Outcome

1998

Other Studies

14 other study(ies) available for ono 1078 and ozagrel

ArticleYear
Leukotriene C4 D4 antagonist markedly reduced inflammation in a rat model of inflammatory bowel disease.
    Gastroenterologia Japonica, 1992, Volume: 27, Issue:6

    Topics: Animals; Chromones; Colon; Inflammation; Inflammatory Bowel Diseases; Methacrylates; Phenylpropionates; Rats; SRS-A

1992
[Changes in arachidonic acid-induced respiratory distress in streptozotocin-diabetic mice].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1992, Volume: 99, Issue:2

    Topics: Animals; Arachidonic Acid; Chromones; Cyclooxygenase Inhibitors; Depression, Chemical; Diabetes Mellitus, Experimental; Male; Methacrylates; Mice; Respiration; SRS-A; Streptozocin; Thromboxane-A Synthase

1992
Inhibition of endothelin-induced bronchoconstriction by OKY-046, a selective thromboxane A2 synthetase inhibitor, in guinea pigs.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1991, Volume: 21A

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Atropine; Bridged Bicyclo Compounds; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Chromones; Endothelins; Fatty Acids, Monounsaturated; Guinea Pigs; Histamine; Indomethacin; Male; Methacrylates; Pyrilamine; Thromboxane B2; Thromboxane-A Synthase

1991
[Eicosanoids in bronchial asthma].
    Nihon rinsho. Japanese journal of clinical medicine, 1990, Volume: 48, Issue:6

    Topics: Acrylates; Arachidonic Acids; Asthma; Benzoquinones; Bronchoalveolar Lavage Fluid; Chromones; Cyclooxygenase Inhibitors; Humans; Indomethacin; Leukocytes; Lipoxygenase Inhibitors; Lung; Macrophages; Methacrylates; Quinones; Thromboxane-A Synthase

1990
[The effect of leukotriene C4/D4 receptor antagonist (ONO-1078) and thromboxane A2 synthetase inhibitor (OKY-046) on airway hyperresponsiveness induced by ozone exposure in guinea pigs].
    Nihon Kyobu Shikkan Gakkai zasshi, 1990, Volume: 28, Issue:2

    Topics: Acrylates; Administration, Inhalation; Animals; Bronchi; Bronchoalveolar Lavage Fluid; Chromones; Guinea Pigs; Methacholine Chloride; Methacholine Compounds; Methacrylates; Muscle Contraction; Ozone; Receptors, Immunologic; Receptors, Leukotriene; Thromboxane A2

1990
Effects of a new thromboxane A2-antagonist (ONO-3708) and a new leukotriene-antagonist (ONO-1078) on thromboxane A2 analogue-, leukotriene C4-, and D4-induced regional myocardial blood flow reduction.
    Heart and vessels, 1988, Volume: 4, Issue:2

    Topics: Animals; Blood Flow Velocity; Chromones; Coronary Circulation; Coronary Disease; Dogs; Male; Methacrylates; SRS-A; Thromboxane A2; Thromboxane-A Synthase

1988
Effect of leukotriene C4D4 antagonist on colonic damage induced by intracolonic administration of trinitrobenzene sulfonic acid in rats.
    Journal of gastroenterology, 1995, Volume: 30, Issue:1

    Topics: Animals; Chromones; Colon; Disease Models, Animal; Eicosanoids; Female; Inflammatory Bowel Diseases; Leukotriene C4; Leukotriene D4; Methacrylates; Peroxidase; Phenylpropionates; Rats; Rats, Sprague-Dawley; SRS-A; Thromboxane-A Synthase; Trinitrobenzenesulfonic Acid

1995
Pharmacological studies of platelet-activating factor (PAF)-induced augmentation of response to histamine in guinea-pigs.
    Prostaglandins, leukotrienes, and essential fatty acids, 1994, Volume: 51, Issue:2

    Topics: Animals; Benzoquinones; Bridged Bicyclo Compounds; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Capillary Permeability; Chromones; Drug Interactions; Fatty Acids, Monounsaturated; Guinea Pigs; Histamine; Indomethacin; Leukocyte Count; Leukotriene Antagonists; Lipoxygenase Inhibitors; Male; Methacrylates; Phospholipid Ethers; Platelet Activating Factor; Pressure; Respiratory Physiological Phenomena; Respiratory System; Thromboxane A2

1994
Inhibitory effect of a peptide leukotriene antagonist ONO-1078 on LTD4- and antigen-induced thromboxane B2 production in guinea pig lungs.
    Life sciences, 1993, Volume: 52, Issue:12

    Topics: Animals; Antigens; Bordetella pertussis; Chromones; Dose-Response Relationship, Drug; Guinea Pigs; Indomethacin; Kinetics; Lung; Male; Methacrylates; Ovalbumin; SRS-A; Thromboxane B2; Thromboxane-A Synthase

1993
An airway hyperresponsiveness model in rat allergic asthma.
    Arerugi = [Allergy], 1993, Volume: 42, Issue:2

    Topics: Acetylcholine; Animals; Ascaris; Asthma; Bronchial Hyperreactivity; Capillary Permeability; Chromones; Depression, Chemical; Dinitrophenols; Disease Models, Animal; Male; Methacrylates; Phospholipid Ethers; Platelet Activating Factor; Rats; Rats, Wistar; SRS-A; Thromboxane-A Synthase; Tissue Extracts

1993
Effects of Y-24180, a long-acting and potent antagonist to platelet-activating factor, on immediate asthmatic response in guinea pigs.
    Pharmacology, 1997, Volume: 54, Issue:1

    Topics: Animals; Anti-Asthmatic Agents; Asthma; Azepines; Benzoquinones; Bronchodilator Agents; Chromones; Drug Interactions; Drug Therapy, Combination; Guinea Pigs; Heptanoic Acids; Male; Methacrylates; Platelet Activating Factor; Theophylline; Triazoles

1997
Suppressive effects of Y-24180, a receptor antagonist to platelet activating factor (PAF), on antigen-induced asthmatic responses in guinea pigs.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1997, Volume: 46, Issue:4

    Topics: Administration, Oral; Aerosols; Animals; Anti-Allergic Agents; Anti-Asthmatic Agents; Asthma; Azepines; Benzoquinones; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchodilator Agents; Chromones; Enzyme Inhibitors; Guinea Pigs; Heptanoic Acids; Histamine Antagonists; Leukotriene Antagonists; Male; Methacrylates; Ovalbumin; Platelet Membrane Glycoproteins; Pyrilamine; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Serine Proteinase Inhibitors; Signal Transduction; Theophylline; Thromboxane-A Synthase; Triazoles

1997
Airway responsiveness in transgenic mice overexpressing platelet-activating factor receptor. Roles of thromboxanes and leukotrienes.
    American journal of respiratory and critical care medicine, 1997, Volume: 156, Issue:5

    Topics: Animals; Azepines; Bronchi; Bronchial Hyperreactivity; Chromones; Indoles; Indomethacin; Leukotriene Antagonists; Leukotrienes; Lipoxygenase Inhibitors; Lung; Methacrylates; Mice; Mice, Transgenic; Phenylpropionates; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Leukotriene B4; Thromboxanes; Triazoles

1997
Beneficial effect of combination therapy with ozagrel and pranlukast in exercise-induced asthma demonstrated by krypton-81 m ventilation scintigraphy--a case report.
    Annals of the Academy of Medicine, Singapore, 2000, Volume: 29, Issue:6

    Topics: Asthma, Exercise-Induced; Chromones; Drug Therapy, Combination; Enzyme Inhibitors; Female; Follow-Up Studies; Humans; Krypton Radioisotopes; Leukotriene Antagonists; Methacrylates; Middle Aged; Radionuclide Imaging; Respiratory Function Tests; Severity of Illness Index; Treatment Outcome

2000