ono 1078 has been researched along with ovalbumin in 29 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 11 (37.93) | 18.2507 |
| 2000's | 16 (55.17) | 29.6817 |
| 2010's | 2 (6.90) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aishita, H; Kobayashi, T; Nakagawa, N; Obata, T; Okada, Y; Terawaki, T | 1 |
| Ishii, A; Miyamoto, T; Mizushima, Y; Motoishi, M; Nakagawa, T; Nambu, F; Shida, T; Yui, Y | 1 |
| Aishita, H; Nakagawa, N; Obata, T; Okada, Y; Terawaki, T | 1 |
| Aishita, H; Furuya, T; Kobayashi, T; Muryobayashi, K; Nakagawa, N; Nambu, F; Obata, T; Okada, Y; Sawada, M; Terawaki, T | 1 |
| Asakura, K; Kataura, A; Narita, S; Shirasaki, H | 2 |
| Iwahisa, Y; Kagoshima, M; Kawakami, Y; Matsuura, M; Terasawa, M; Tomomatsu, N; Yamaguchi, S | 1 |
| Fujita, M; Kawabata, K; Nakagawa, N; Ohno, H; Takeda, H; Yonetomi, Y | 1 |
| Khawaja, AM; Liu, YC; Rogers, DF | 1 |
| Aze, Y; Fujita, M; Kawabata, K; Ohno, H; Shimouchi, K; Takeda, H; Yonetomi, Y | 1 |
| Kohno, S; Nabe, T; Tomioka, H; Yamashita, K | 1 |
| Hirano, H; Majima, Y; Sakakura, Y; Shimizu, T | 1 |
| Arakida, Y; Honda, K; Miyata, K; Morio, H; Ohga, K; Okada, Y; Suwa, K; Yamada, T; Yokota, M | 1 |
| Arakida, Y; Morio, H; Ohga, K; Okada, Y; Suwa, K; Yamada, T; Yokota, M | 1 |
| Abe, M; Hugli, TE; Kamiya, H; Katsuragi, T; Kodani, M; Sakata, N; Takano, Y | 1 |
| Hirasawa, N; Honda, M; Okada, M; Ozawa, M; Sano, K; Shirota, H; Tagami, H; Tamura, G; Terui, T | 1 |
| Kawai, T; Kohno, S; Miura, M; Nabe, T; Yamashita, K | 1 |
| Hattori, R; Majima, Y; Shimizu, S; Shimizu, T | 1 |
| Wei, EQ; Yang, XH | 1 |
| Dohi, M; Nakagome, K; Okunishi, K; Tanaka, R; Yamamoto, K | 1 |
| Jin, GY; Kim, SR; Lee, KS; Lee, YC; Park, HS | 1 |
| Cui, S; Kurata, Y; Liu, W; Ruan, Z; Shibamoto, T | 1 |
| Jin, SM; Kim, SR; Lee, KS; Lee, KY; Lee, YC; Min, KH; Park, HS; Park, SJ | 1 |
| Cui, S; Kurata, Y; Shibamoto, T; Takano, H; Zhang, W | 1 |
| Iwasaki, H; Kato, T; Miyagawa, N; Shibata, T; Tanaka, M; Wakitani, K | 2 |
| Ishinaga, H; Majima, Y; Sakaida, H; She, W; Suzuki, S; Takeuchi, K | 1 |
| Inui, S; Mizutani, N; Nabe, T; Yoshino, S | 1 |
| Hur, J; Kang, JY; Kim, YK; Lee, SY; Rhee, CK | 1 |
1 trial(s) available for ono 1078 and ovalbumin
| Article | Year |
|---|---|
Effect of leukotriene antagonist on experimental and clinical bronchial asthma.
Topics: Allergens; Anaphylaxis; Animals; Asthma; Bronchi; Bronchial Provocation Tests; Chromones; Drug Evaluation; Drug Evaluation, Preclinical; Dust; Guinea Pigs; Histamine; Humans; Immunization, Passive; Indomethacin; Male; Ovalbumin; Pyrilamine; SRS-A | 1991 |
28 other study(ies) available for ono 1078 and ovalbumin
| Article | Year |
|---|---|
Effect of a peptide leukotriene antagonist, ONO-1078 on antigen-induced airway microvascular leakage in actively sensitized guinea pigs.
Topics: Analysis of Variance; Animals; Bordetella pertussis; Bronchodilator Agents; Capillary Permeability; Chromones; Evans Blue; Extravasation of Diagnostic and Therapeutic Materials; Guinea Pigs; Male; Ovalbumin; Phthalazines; Respiratory Hypersensitivity; Respiratory Physiological Phenomena; Respiratory System; SRS-A | 1992 |
Inhibitory effect of a peptide leukotriene antagonist ONO-1078 on LTD4- and antigen-induced thromboxane B2 production in guinea pig lungs.
Topics: Animals; Antigens; Bordetella pertussis; Chromones; Dose-Response Relationship, Drug; Guinea Pigs; Indomethacin; Kinetics; Lung; Male; Methacrylates; Ovalbumin; SRS-A; Thromboxane B2; Thromboxane-A Synthase | 1993 |
Effect of a peptide leukotriene receptor antagonist, ONO-1078, on guinea-pig models of asthma.
Topics: Acetylcholine; Acute-Phase Reaction; Animals; Asthma; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Bronchodilator Agents; Chromones; Disease Models, Animal; Guinea Pigs; Hypersensitivity; Immunization; Male; Ovalbumin; Phthalazines; Pulmonary Eosinophilia; Pyrilamine; SRS-A | 1993 |
Effects of a cysteinyl leukotriene antagonist, ONO-1078 (pranlukast), on total airway resistance after antigen challenge in sensitized guinea pigs.
Topics: Administration, Topical; Airway Resistance; Animals; Anti-Asthmatic Agents; Chromones; Cysteine; Disease Models, Animal; Eosinophils; Guinea Pigs; Leukotriene Antagonists; Nasal Mucosa; Ovalbumin; Plethysmography; Rhinitis, Allergic, Perennial; Serine Proteinase Inhibitors | 1997 |
Suppressive effects of Y-24180, a receptor antagonist to platelet activating factor (PAF), on antigen-induced asthmatic responses in guinea pigs.
Topics: Administration, Oral; Aerosols; Animals; Anti-Allergic Agents; Anti-Asthmatic Agents; Asthma; Azepines; Benzoquinones; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchodilator Agents; Chromones; Enzyme Inhibitors; Guinea Pigs; Heptanoic Acids; Histamine Antagonists; Leukotriene Antagonists; Male; Methacrylates; Ovalbumin; Platelet Membrane Glycoproteins; Pyrilamine; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Serine Proteinase Inhibitors; Signal Transduction; Theophylline; Thromboxane-A Synthase; Triazoles | 1997 |
Effects of a specific cysteinyl leukotriene antagonist, pranlukast, on antigen-induced cysteinyl leukotriene-mediated rhinitis in guinea pigs.
Topics: Airway Resistance; Animals; Anti-Allergic Agents; Anti-Asthmatic Agents; Chromones; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Guinea Pigs; Histamine H1 Antagonists; Indomethacin; Leukotriene Antagonists; Nasal Mucosa; Ovalbumin; Phthalazines; Pyrilamine; Rhinitis, Allergic, Perennial; SRS-A; Thromboxane B2 | 1997 |
Effects of the cysteinyl leukotriene receptor antagonists pranlukast and zafirlukast on tracheal mucus secretion in ovalbumin-sensitized guinea-pigs in vitro.
Topics: Adenosine Triphosphate; Animals; Anti-Asthmatic Agents; Binding, Competitive; Chromones; Cysteine; Guinea Pigs; Hypersensitivity; In Vitro Techniques; Indoles; Leukotriene Antagonists; Leukotriene D4; Male; Membrane Proteins; Mucus; Ovalbumin; Passive Cutaneous Anaphylaxis; Phenylcarbamates; Receptors, Leukotriene; Sulfates; Sulfonamides; Sulfur Radioisotopes; Tosyl Compounds; Trachea | 1998 |
The effect of a cysteinyl leukotriene antagonist, ONO-1078 (pranlukast) on agonist- and antigen-induced nasal microvascular leakage in guinea pigs.
Topics: Animals; Anti-Asthmatic Agents; Chromones; Disease Models, Animal; Guinea Pigs; Leukotriene Antagonists; Leukotriene D4; Male; Membrane Proteins; Ovalbumin; Receptors, Leukotriene; Rhinitis, Allergic, Perennial | 1998 |
Involvement of cysteinyl leukotrienes in biphasic increase of nasal airway resistance of antigen-induced rhinitis in guinea pigs.
Topics: Airway Resistance; Animals; Chromones; Cysteine; Disease Models, Animal; Guinea Pigs; Leukotriene Antagonists; Leukotrienes; Male; Nasal Mucosa; Ovalbumin; Rhinitis, Allergic, Perennial; Serine Proteinase Inhibitors | 1999 |
Repeated antigen inhalations alter chemical mediators that cause asthmatic obstruction in guinea pigs.
Topics: Administration, Inhalation; Airway Obstruction; Aluminum Hydroxide; Animals; Antigens; Asthma; Benzoquinones; Chromones; Eosinophilia; Guinea Pigs; Heptanoic Acids; Histamine H1 Antagonists; Leukotriene Antagonists; Lung; Male; Ovalbumin; Prostaglandin Antagonists; Pyrilamine; Thromboxane A2 | 1999 |
A mechanism of antigen-induced mucus production in nasal epithelium of sensitized rats. A comparison with lipopolysaccharide-induced mucus production.
Topics: Animals; Antigens; Chlorpheniramine; Chromones; Cimetidine; Dexamethasone; Eosinophils; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Immune Sera; Immunization; Leukotriene Antagonists; Lipopolysaccharides; Male; Mucus; Nasal Mucosa; Neutrophils; Ovalbumin; Rats; Rats, Inbred F344; Rhinitis, Allergic, Perennial | 2000 |
Effect of YM158, a dual lipid mediator antagonist, on immediate and late asthmatic responses, and on airway hyper-responsiveness in guinea pigs.
Topics: Acetylcholine; Airway Resistance; Animals; Anti-Asthmatic Agents; Antigens; Asthma; Benzoquinones; Bronchial Hyperreactivity; Bronchial Provocation Tests; Chromones; Dose-Response Relationship, Immunologic; Guinea Pigs; Heptanoic Acids; Hypersensitivity, Delayed; Hypersensitivity, Immediate; Leukotriene Antagonists; Male; Membrane Proteins; Ovalbumin; Ozone; Receptors, Leukotriene; Receptors, Thromboxane; Tetrazoles; Thiazoles | 2000 |
Effect of combined leukotriene D(4) and thromboxane A(2) receptor antagonist on mediator-controlled resistance in guinea pigs.
Topics: Administration, Oral; Airway Resistance; Animals; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Antigens; Asthma; Benzoquinones; Chromones; Dose-Response Relationship, Drug; Guinea Pigs; Heptanoic Acids; Indomethacin; Leukotriene Antagonists; Leukotriene B4; Leukotriene C4; Leukotriene E4; Lipid Metabolism; Lung; Male; Membrane Proteins; Ovalbumin; Receptors, Leukotriene; Receptors, Thromboxane; Tetrazoles; Thiazoles; Thromboxane B2; Time Factors | 2000 |
Intratracheal administration of anaphylatoxin C5a potentiates antigen-induced pulmonary reactions through the prolonged production of cysteinyl-leukotrienes.
Topics: Airway Resistance; Animals; Antigens; Bile; Chromones; Complement C5a; Complement C5a, des-Arginine; Cysteine; Diphenhydramine; Histamine H1 Antagonists; Hypersensitivity, Immediate; Inflammation Mediators; Injections, Subcutaneous; Intubation, Intratracheal; Leukotriene Antagonists; Leukotriene D4; Leukotriene E4; Leukotrienes; Lung; Male; Membrane Proteins; Ovalbumin; Rats; Rats, Inbred BN; Receptors, Leukotriene; Zymosan | 2000 |
Production and pharmacologic modulation of the granulocyte-associated allergic responses to ovalbumin in murine skin models induced by injecting ovalbumin-specific Th1 or Th2 cells.
Topics: Animals; Cells, Cultured; Chromones; Dermatitis, Atopic; Disease Models, Animal; Ear; Edema; Enzyme Inhibitors; Eosinophils; Hypersensitivity; Immunosuppressive Agents; Leukotriene Antagonists; Male; Mice; Mice, Inbred BALB C; Neutrophils; Ovalbumin; Oxadiazoles; Pyrimidinones; Skin; Tacrolimus; Th1 Cells; Th2 Cells | 2001 |
Cysteinyl leukotriene-dependent interleukin-5 production leading to eosinophilia during late asthmatic response in guinea-pigs.
Topics: Animals; Asthma; Cell Survival; Chromones; Cysteine; Eosinophilia; Guinea Pigs; Interleukin-5; Kinetics; Leukotriene Antagonists; Leukotrienes; Male; Membrane Proteins; Ovalbumin; Pulmonary Eosinophilia; Receptors, Leukotriene; Thiazoles | 2002 |
A mechanism of antigen-induced goblet cell degranulation in the nasal epithelium of sensitized rats.
Topics: Animals; Antigens; Atropine; Cell Degranulation; Chromones; Cimetidine; Eosinophils; Histamine; Indomethacin; Mucus; Nasal Mucosa; Neutrophils; Ovalbumin; Rats | 2003 |
[Expression of vascular cell adhesion molecule-1 in lung slices from antigen sensitized rats and pharmacological modulation].
Topics: Animals; Chromones; Dexamethasone; Female; In Vitro Techniques; Lung; Male; Ovalbumin; Piperidines; Quinuclidines; Rats; Rats, Sprague-Dawley; Vascular Cell Adhesion Molecule-1 | 2003 |
A novel role of cysteinyl leukotrienes to promote dendritic cell activation in the antigen-induced immune responses in the lung.
Topics: Adjuvants, Immunologic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antigens; Arachidonate 5-Lipoxygenase; Bronchial Hyperreactivity; CD4-Positive T-Lymphocytes; Cells, Cultured; Chromones; Cysteine; Dendritic Cells; Inflammation; Leukotriene Antagonists; Leukotrienes; Lung; Male; Membrane Proteins; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Ovalbumin; Receptors, Leukotriene; Th1 Cells | 2004 |
Cysteinyl leukotriene receptor antagonist regulates vascular permeability by reducing vascular endothelial growth factor expression.
Topics: Acetates; Animals; Bronchial Hyperreactivity; Capillary Permeability; Chromones; Cyclopropanes; Cytokines; Female; Indoles; Membrane Proteins; Mice; Mice, Inbred BALB C; NF-kappa B; Ovalbumin; Quinolines; Receptors, Leukotriene; Receptors, Vascular Endothelial Growth Factor; Sulfides; Transcription Factor RelA; Vascular Endothelial Growth Factor A | 2004 |
Involvement of platelet-activating factor and leukotrienes in anaphylactic segmental venoconstriction in ovalbumin sensitized guinea pig livers.
Topics: Animals; Chromones; Guinea Pigs; Leukotrienes; Liver; Male; Organ Size; Ovalbumin; Platelet Activating Factor; Vasoconstriction; Veins | 2005 |
Cysteinyl leukotriene upregulates IL-11 expression in allergic airway disease of mice.
Topics: Acetates; Animals; Bronchoalveolar Lavage Fluid; Cells, Cultured; Chromones; Collagen; Cyclopropanes; Epithelial Cells; Female; Interleukin-11; Interleukin-13; Interleukin-4; Leukotriene Antagonists; Leukotriene C4; Leukotriene D4; Lung; Mice; Mice, Inbred C57BL; Nitriles; Ovalbumin; Quinolines; Respiratory Hypersensitivity; RNA, Messenger; Sulfides; Sulfones; Transcription Factor RelA | 2007 |
Leukotrienes and cyclooxygenase products mediate anaphylactic venoconstriction in ovalbumin sensitized rat livers.
Topics: Anaphylaxis; Animals; Antigens; Chromones; Cyclooxygenase Inhibitors; In Vitro Techniques; Indomethacin; Leukotriene Antagonists; Leukotrienes; Liver; Male; Organ Size; Ovalbumin; Oxygen Consumption; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Vascular Resistance; Vasoconstriction; Venous Pressure | 2007 |
Two pharmacological phases in antigen-induced immediate airway response in rats.
Topics: Administration, Inhalation; Adrenergic alpha-2 Receptor Agonists; Adrenergic beta-Agonists; Albuterol; Animals; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Antigens; Benzoquinones; Bronchial Hyperreactivity; Chromones; Heptanoic Acids; Histamine H2 Antagonists; Hypersensitivity, Immediate; Ketotifen; Leukotriene Antagonists; Male; Ovalbumin; p-Methoxy-N-methylphenethylamine; Prednisolone; Rats; Rats, Sprague-Dawley; Thromboxane A2 | 2008 |
Pharmacological analysis of antigen-induced late airway response in rats.
Topics: Albuterol; Animals; Anti-Asthmatic Agents; Bronchoalveolar Lavage Fluid; Chromones; Eosinophils; Ketotifen; Leukocyte Count; Male; Ovalbumin; Prednisolone; Pulmonary Edema; Rats; Rats, Sprague-Dawley; Respiratory Hypersensitivity; Time Factors | 2009 |
Remodeling of nasal mucosa by allergen exposure in guinea pigs is suppressed by steroid and pranlukast.
Topics: Analysis of Variance; Animals; Chromones; Guinea Pigs; Leukotriene Antagonists; Nasal Mucosa; Ovalbumin; Random Allocation; Steroids | 2009 |
Intratracheal sensitization/challenge-induced biphasic asthmatic response and airway hyperresponsiveness in guinea pigs.
Topics: Airway Resistance; Animals; Anti-Asthmatic Agents; Antigens; Asthma; Bronchial Hyperreactivity; Chromones; Dexamethasone; Disease Models, Animal; Guinea Pigs; Histamine; Lung; Male; Ovalbumin; Theophylline; Trachea | 2010 |
The leukotriene receptor antagonist pranlukast attenuates airway remodeling by suppressing TGF-β signaling.
Topics: Airway Remodeling; Animals; Asthma; Cell Line; Chromones; Collagen; Disease Models, Animal; Female; Fibroblasts; Humans; Leukotriene Antagonists; Mice; Mice, Inbred BALB C; Ovalbumin; Signal Transduction; Smad Proteins; Transforming Growth Factor beta1 | 2018 |