ono 1078 has been researched along with montelukast in 36 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (22.22) | 18.2507 |
| 2000's | 18 (50.00) | 29.6817 |
| 2010's | 9 (25.00) | 24.3611 |
| 2020's | 1 (2.78) | 2.80 |
| Authors | Studies |
|---|---|
| Brooks, CD; Summers, JB | 1 |
| Gelens, E; Nederkoorn, PH; Schoenmakers, SH; Timmerman, H; Zhang, MQ; Zwaagstra, ME | 1 |
| Abramovitz, M; Austin, CP; Bai, C; Caskey, CT; Chateauneuf, A; Connolly, BM; Coulombe, N; Evans, JF; Figueroa, DJ; Ford-Hutchinson, AW; Greig, GM; Hooks, SB; Hosfield, E; Im, DS; Kargman, S; Liu, Q; Lynch, KR; Metters, KM; O'Neill, GP; Sawyer, N; Stocco, R; Williams, DL; Zeng, Z | 1 |
| Ames, RS; Bergsma, DJ; Buckley, PT; Chambers, J; Dytko, GM; Ellis, C; Elshourbagy, N; Foley, JJ; Halsey, W; Hay, DW; Herrity, NC; Jenkins, O; Muccitelli, RM; Muir, AI; Murdock, PR; Nuthulaganti, P; Sarau, HM; Sathe, G; Schmidt, DB; Wilson, S | 1 |
| Capra, V; Nicosia, S; Panigalli, T; Ravasi, S; Rovati, GE | 1 |
| Anton, P; Bonjoch, J; Diaba, F; Miralpeix, M; Pagès, L; Pérez, D; Puig, C; Soca, L; Vilella, D | 1 |
| Dong, X; Du, L; Hu, Y; Huang, X; Liu, T; Wang, L; Wei, E; Yang, B | 1 |
| Gillard, M; Köse, M; Kostenis, E; Müller, CE; Ritter, K; Thiemke, K | 1 |
| Aratani, Y; Egashira, H; Fujita, M; Hisaichi, K; Ima, M; Imagawa, A; Inoue, A; Ishida, A; Itadani, S; Kadode, M; Kinoshita, A; Kitamine, T; Matsumura, N; Moriguchi, H; Nabe, T; Nakao, T; Nakayama, Y; Nomura, H; Ohmoto, K; Ohta, N; Sekiguchi, T; Sekioka, T; Tajima, Y; Takahashi, S; Takeuchi, J; Ueda, J; Yamaura, Y; Yashiro, K; Yonetomi, Y | 1 |
| Tan, RA | 1 |
| Bernstein, PR | 1 |
| Rosenwasser, LJ | 1 |
| Drazen, JM; Pauwels, R; Wechsler, ME | 1 |
| García-Marcos, L; Schuster, A | 1 |
| Adachi, M; Minoguchi, K | 1 |
| Kemp, JP | 1 |
| Chen, Z; Chu, LS; Mei, RH; Wei, EQ; Xu, HM; Yu, GL; Zhang, Q; Zhang, SH; Zhang, WP; Zhao, MH | 1 |
| Jin, GY; Kim, SR; Lee, KS; Lee, YC; Park, HS | 1 |
| Abbracchio, MP; Accomazzo, MR; Capra, V; Ferrario, S; Fumagalli, M; Gao, ZG; Jacobson, KA; Mamedova, L; Rovati, GE | 1 |
| Hiyama, Y; Ishimura, M; Kataoka, S; Maeda, T; Suda, M | 1 |
| Koyabu, N; Kuwano, M; Murakami, H; Nakamura, T; Ohtani, H; Satoh, H; Sawada, Y; Tsujimoto, M; Uchiumi, T; Ushigome, F; Yamashita, F | 1 |
| Jin, SM; Kim, SR; Lee, KS; Lee, KY; Lee, YC; Min, KH; Park, HS; Park, SJ | 1 |
| Guillevin, L; Guilpain, P; Lhote, F; Mouthon, L; Pagnoux, C | 1 |
| Culp, JA; Steinke, JW | 1 |
| Ge, QF; Hu, X; Wei, EQ; Zhang, WP | 1 |
| Chohnabayashi, N; Nishimura, N; Sugiura, R | 1 |
| Baba, K; Okubo, K | 1 |
| Akamatsu, K; Hirano, T; Ichikawa, T; Ichinose, M; Koarai, A; Matsunaga, K; Minakata, Y; Sugiura, H; Yanagisawa, S | 1 |
| Drakatos, P; Karkoulias, K; Lykouras, D; Sampsonas, F; Spiropoulos, K | 1 |
| Houkin, K; Imai, K; Ishitani, K; Ito, Y; Kobayashi, H; Muraki, T; Nozaki, M; Yoshikawa, M | 1 |
| Fang, SH; Shi, WZ; Wei, EQ; Zhang, YM; Zhao, R | 1 |
| Kohno, S; Matsuse, H | 1 |
| Anderson, R; Feldman, C; Gravett, CM; Steel, HC; Theron, AJ; Tintinger, GR | 1 |
| Arroyo, DS; Iribarren, P; Jesse, AC; Lenz, QF; Marafiga, JR; Masson, CJ; Mello, CF; Poersch, AB; Reschke, CR; Temp, FR | 1 |
| Akhbari, M; Harris, KM; Kneale, D; Pike, KC | 1 |
| Goto, M; Hatakeyama, S; Kosaki, R; Murashima, A; Nagase, S; Ogura, J; Takahashi, K; Tsutsumi, S; Watanabe, N; Yakuwa, N; Yamaguchi, H; Yamamoto, A; Yamane, R | 1 |
13 review(s) available for ono 1078 and montelukast
| Article | Year |
|---|---|
Modulators of leukotriene biosynthesis and receptor activation.
Topics: 5-Lipoxygenase-Activating Proteins; Animals; Carrier Proteins; Forecasting; Humans; Leukotriene B4; Leukotrienes; Lipoxygenase Inhibitors; Membrane Proteins; Molecular Structure; Receptors, Leukotriene | 1996 |
The role of antileukotrienes in asthma management.
Topics: Acetates; Animals; Anti-Asthmatic Agents; Asthma; Chromones; Cyclopropanes; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Lipoxygenase Inhibitors; Phenylcarbamates; Quinolines; Sulfides; Sulfonamides; Tosyl Compounds | 1998 |
Chemistry and structure--activity relationships of leukotriene receptor antagonists.
Topics: Acetates; Anti-Asthmatic Agents; Biological Availability; Chromones; Cyclopropanes; Indoles; Leukotriene Antagonists; Leukotrienes; Lipoxygenase Inhibitors; Phenylcarbamates; Quinolines; SRS-A; Structure-Activity Relationship; Sulfides; Sulfonamides; Tosyl Compounds | 1998 |
Antileukotrienes in asthma: present situation.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Chromones; Clinical Trials as Topic; Cyclopropanes; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Leukotrienes; Phenylcarbamates; Quinolines; Sulfides; Sulfonamides; Tosyl Compounds | 2001 |
[Leukotriene modifiers].
Topics: Acetates; Asthma; Chromones; Cyclopropanes; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Leukotrienes; Lipoxygenase Inhibitors; Membrane Proteins; Phenylcarbamates; Practice Guidelines as Topic; Quinolines; Receptors, Leukotriene; Sulfides; Sulfonamides; Tosyl Compounds | 2001 |
Recent advances in the management of asthma using leukotriene modifiers.
Topics: Acetates; Administration, Inhalation; Adolescent; Adult; Asthma; Child; Child, Preschool; Chromones; Controlled Clinical Trials as Topic; Cyclopropanes; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydroxyurea; Leukotriene Antagonists; Male; Middle Aged; Peak Expiratory Flow Rate; Quinolines; Respiratory Function Tests; Severity of Illness Index; Sulfides; Treatment Outcome | 2003 |
[Antileukotrienes and Churg-Strauss syndrome].
Topics: Acetates; Adult; Anti-Asthmatic Agents; Antibodies, Antineutrophil Cytoplasmic; Asthma; Chromones; Churg-Strauss Syndrome; Cohort Studies; Cyclopropanes; Humans; Incidence; Indoles; Leukotriene Antagonists; Leukotrienes; Phenylcarbamates; Quinolines; Retrospective Studies; Sulfides; Sulfonamides; Tosyl Compounds | 2007 |
Leukotriene synthesis inhibitors versus antagonists: the pros and cons.
Topics: Acetates; Animals; Anti-Asthmatic Agents; Arachidonate 5-Lipoxygenase; Asthma; Chromones; Cyclopropanes; Humans; Hypersensitivity; Indoles; Inflammation Mediators; Leukotriene Antagonists; Leukotrienes; Lipoxygenase Inhibitors; Phenylcarbamates; Quinolines; Receptors, Leukotriene; Sulfides; Sulfonamides; Tosyl Compounds | 2007 |
[Adverse effects of leukotriene-antagonists].
Topics: Acetates; Anaphylaxis; Chemical and Drug Induced Liver Injury; Chromones; Cyclopropanes; Drug Interactions; Enzyme Inhibitors; Hematologic Diseases; Humans; Indoles; Leukotriene Antagonists; Lipoxygenase Inhibitors; Lung Diseases, Interstitial; Membrane Proteins; Phenylcarbamates; Quinolines; Receptors, Leukotriene; Sulfides; Sulfonamides; Tosyl Compounds | 2007 |
Targeting leukotrienes for the treatment of COPD?
Topics: 5-Lipoxygenase-Activating Proteins; Acetates; Arachidonate 5-Lipoxygenase; Bronchoconstriction; Capillary Permeability; Carrier Proteins; CD8-Positive T-Lymphocytes; Cell Movement; Chromones; Cyclopropanes; Eosinophils; Humans; Indoles; Leukotriene Antagonists; Leukotrienes; Membrane Proteins; Neutrophils; Phenylcarbamates; Pulmonary Disease, Chronic Obstructive; Quinolines; Sulfides; Sulfonamides; Tosyl Compounds | 2009 |
Leukotriene receptor antagonists pranlukast and montelukast for treating asthma.
Topics: Acetates; Animals; Anti-Asthmatic Agents; Asthma; Chromones; Cyclopropanes; Cysteine; Humans; Leukotriene Antagonists; Leukotrienes; Quinolines; Sulfides | 2014 |
Cysteinyl leukotriene receptor-1 antagonists as modulators of innate immune cell function.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Acetates; Anti-Asthmatic Agents; Arachidonate 5-Lipoxygenase; Asthma; Chromones; Cyclopropanes; Gene Expression Regulation; Humans; Immunity, Innate; Immunologic Factors; Indoles; Leukotriene Antagonists; Monocytes; Neutrophils; NF-kappa B; Phenylcarbamates; Quinolines; Receptors, Leukotriene; Sulfides; Sulfonamides; Tosyl Compounds | 2014 |
Interventions for autumn exacerbations of asthma in children.
Topics: Acetates; Adrenal Cortex Hormones; Anti-Allergic Agents; Anti-Asthmatic Agents; Asthma; Behavior Therapy; Child; Chromones; Cyclopropanes; Disease Progression; Humans; Leukotriene Antagonists; Omalizumab; Quinolines; Randomized Controlled Trials as Topic; Seasons; Sulfides | 2018 |
2 trial(s) available for ono 1078 and montelukast
| Article | Year |
|---|---|
A double-blind non-inferiority clinical study of montelukast, a cysteinyl leukotriene receptor 1 antagonist, compared with pranlukast in patients with seasonal allergic rhinitis.
Topics: Acetates; Adult; Chromones; Cyclopropanes; Double-Blind Method; Female; Humans; Leukotriene Antagonists; Male; Middle Aged; Nasal Obstruction; Quinolines; Rhinitis, Allergic, Seasonal; Severity of Illness Index; Sleep Initiation and Maintenance Disorders; Sneezing; Sulfides; Treatment Outcome | 2008 |
Molecular mechanism of the additive effects of leukotriene modifier in asthmatic patients receiving steroid therapy.
Topics: Acetates; Administration, Inhalation; Adrenal Cortex Hormones; Adult; Asthma; Chemokine CCL5; Chromones; Cyclopropanes; Cysteine; Cytokines; Drug Synergism; Female; Forced Expiratory Volume; Humans; Leukotriene Antagonists; Leukotrienes; Male; Middle Aged; Quinolines; Sulfides | 2009 |
21 other study(ies) available for ono 1078 and montelukast
| Article | Year |
|---|---|
Development of a three-dimensional CysLT1 (LTD4) antagonist model with an incorporated amino acid residue from the receptor.
Topics: Arginine; Flavonoids; Leukotriene Antagonists; Membrane Proteins; Models, Molecular; Molecular Conformation; Quinolines; Receptors, Leukotriene | 1998 |
Characterization of the human cysteinyl leukotriene CysLT1 receptor.
Topics: Amino Acid Sequence; Animals; Base Sequence; Blotting, Northern; Chromosome Mapping; Cloning, Molecular; COS Cells; Humans; Leukotriene Antagonists; Leukotriene D4; Lung; Macrophages, Alveolar; Membrane Proteins; Molecular Sequence Data; Muscle, Smooth; Receptors, Leukotriene; Tissue Distribution; Transfection; X Chromosome; Xenopus laevis | 1999 |
Identification, molecular cloning, expression, and characterization of a cysteinyl leukotriene receptor.
Topics: Amino Acid Sequence; Base Sequence; Binding Sites; Biological Transport; Calcium; Cells, Cultured; Cloning, Molecular; Humans; Leukotriene D4; Membrane Proteins; Molecular Sequence Data; Pertussis Toxin; Receptors, Leukotriene; Signal Transduction; Virulence Factors, Bordetella | 1999 |
Pharmacological differences among CysLT(1) receptor antagonists with respect to LTC(4) and LTD(4) in human lung parenchyma.
Topics: Acetates; Anti-Asthmatic Agents; Binding, Competitive; Chromones; Cyclopropanes; Humans; Kinetics; Leukotriene Antagonists; Leukotriene C4; Leukotriene D4; Membrane Proteins; Quinolines; Receptors, Leukotriene; Sulfides | 2002 |
Synthesis and structure-activity relationships of gamma-carboline derivatives as potent and selective cysLT(1) antagonists.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Carbolines; Chemistry, Pharmaceutical; Drug Design; Guinea Pigs; Humans; Inhibitory Concentration 50; Leukotriene Antagonists; Models, Chemical; Receptors, Leukotriene; Structure-Activity Relationship; Time Factors | 2009 |
Pharmacophore identification, synthesis, and biological evaluation of carboxylated chalcone derivatives as CysLT1 antagonists.
Topics: Cell Line, Tumor; Chalcone; Databases, Factual; Drug Evaluation, Preclinical; Humans; Leukotriene Antagonists; Models, Molecular; Receptors, Leukotriene | 2010 |
Development of [(3)H]2-Carboxy-4,6-dichloro-1H-indole-3-propionic Acid ([(3)H]PSB-12150): A Useful Tool for Studying GPR17.
Topics: | 2014 |
Discovery of Gemilukast (ONO-6950), a Dual CysLT1 and CysLT2 Antagonist As a Therapeutic Agent for Asthma.
Topics: Animals; Asthma; Biological Availability; Butyrates; Dogs; Guinea Pigs; Humans; Indoles; Leukotriene Antagonists; Rats; Receptors, Leukotriene | 2015 |
Leukotriene modifiers: new drugs, old and new reactions.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Autoimmune Diseases; Chromones; Churg-Strauss Syndrome; Cyclopropanes; Drug Hypersensitivity; Eosinophilia; Humans; Indoles; Leukotriene Antagonists; Leukotrienes; Lupus Erythematosus, Systemic; Phenylcarbamates; Quinolines; Sulfides; Sulfonamides; Th2 Cells; Tosyl Compounds | 1999 |
Leukotriene modifiers and Churg-Strauss syndrome: adverse effect or response to corticosteroid withdrawal?
Topics: Acetates; Adrenal Cortex Hormones; Asthma; Chromones; Churg-Strauss Syndrome; Cyclopropanes; Eosinophils; Female; Humans; Indoles; Leukotriene Antagonists; Leukotrienes; Middle Aged; Phenylcarbamates; Quinolines; Sulfides; Sulfonamides; Tosyl Compounds | 1999 |
Montelukast, a cysteinyl leukotriene receptor-1 antagonist, dose- and time-dependently protects against focal cerebral ischemia in mice.
Topics: Acetates; Animals; Antipyrine; Blood-Brain Barrier; Brain; Brain Edema; Brain Ischemia; Chromones; Cyclopropanes; Dose-Response Relationship, Drug; Edaravone; Free Radical Scavengers; Infarction, Middle Cerebral Artery; Leukotriene Antagonists; Mice; Nervous System; Neuroprotective Agents; Psychomotor Performance; Quinolines; Receptors, Leukotriene; Sulfides; Survival Analysis; Time Factors | 2005 |
Cysteinyl leukotriene receptor antagonist regulates vascular permeability by reducing vascular endothelial growth factor expression.
Topics: Acetates; Animals; Bronchial Hyperreactivity; Capillary Permeability; Chromones; Cyclopropanes; Cytokines; Female; Indoles; Membrane Proteins; Mice; Mice, Inbred BALB C; NF-kappa B; Ovalbumin; Quinolines; Receptors, Leukotriene; Receptors, Vascular Endothelial Growth Factor; Sulfides; Transcription Factor RelA; Vascular Endothelial Growth Factor A | 2004 |
CysLT1 leukotriene receptor antagonists inhibit the effects of nucleotides acting at P2Y receptors.
Topics: Acetates; Base Sequence; Calcium; Chromones; Cyclopropanes; DNA Primers; Humans; Membrane Proteins; Quinolines; Receptors, Leukotriene; Receptors, Purinergic P2; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Sulfides; U937 Cells; Uridine Triphosphate | 2005 |
Effects of KP-496, a novel dual antagonist for leukotriene D4 and thromboxane A2 receptors, on contractions induced by various agonists in the guinea pig trachea.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetates; Acetylcholine; Albuterol; Animals; Atropine; Benzoquinones; Carbachol; Chromones; Cyclopropanes; Dinoprost; Drug Evaluation, Preclinical; Guinea Pigs; Heptanoic Acids; Histamine; In Vitro Techniques; Indoles; Indomethacin; Ketanserin; Ketotifen; Leukotriene Antagonists; Leukotriene D4; Male; Muscle Contraction; Muscle, Smooth; Phenylcarbamates; Powders; Procaterol; Prostaglandin Antagonists; Prostaglandin D2; Quinolines; Receptors, Thromboxane A2, Prostaglandin H2; Serotonin; Substance P; Sulfides; Sulfonamides; Tosyl Compounds; Trachea; Tryptophan | 2006 |
Inhibitory effects of angiotensin II receptor antagonists and leukotriene receptor antagonists on the transport of human organic anion transporter 4.
Topics: Acetates; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biological Transport; Biphenyl Compounds; Blotting, Western; Cell Line; Chromones; Cyclopropanes; Dose-Response Relationship, Drug; Estrone; Humans; Imidazoles; Indoles; Leukotriene Antagonists; Losartan; Molecular Structure; Organic Anion Transporters, Sodium-Independent; Phenylcarbamates; Quinolines; Structure-Activity Relationship; Sulfides; Sulfonamides; Tetrazoles; Tosyl Compounds; Transfection; Tritium; Valine; Valsartan | 2006 |
Cysteinyl leukotriene upregulates IL-11 expression in allergic airway disease of mice.
Topics: Acetates; Animals; Bronchoalveolar Lavage Fluid; Cells, Cultured; Chromones; Collagen; Cyclopropanes; Epithelial Cells; Female; Interleukin-11; Interleukin-13; Interleukin-4; Leukotriene Antagonists; Leukotriene C4; Leukotriene D4; Lung; Mice; Mice, Inbred C57BL; Nitriles; Ovalbumin; Quinolines; Respiratory Hypersensitivity; RNA, Messenger; Sulfides; Sulfones; Transcription Factor RelA | 2007 |
[Effects of cysteinyl receptor agonist and antagonists on rat primary cortical neurons].
Topics: Acetates; Animals; Animals, Newborn; Calcium; Cell Hypoxia; Cell Survival; Cells, Cultured; Cerebral Cortex; Chromones; Cyclopropanes; Glucose; Leukotriene Antagonists; Leukotriene D4; Neurons; Quinolines; Rats; Receptors, Leukotriene; Sulfides | 2007 |
Cysteinyl leukotriene receptor antagonists inhibit tumor metastasis by inhibiting capillary permeability.
Topics: Acetates; Animals; Capillary Permeability; Carcinoma, Lewis Lung; Cell Line, Tumor; Chromones; Colonic Neoplasms; Cyclopropanes; Female; Leukotriene Antagonists; Male; Mice; Neoplasm Metastasis; Neoplastic Cells, Circulating; Quinolines; Rats; Rats, Inbred F344; Sulfides | 2010 |
Montelukast, a cysteinyl leukotriene receptor-1 antagonist, attenuates chronic brain injury after focal cerebral ischaemia in mice and rats.
Topics: Acetates; Administration, Oral; Animals; Antipyrine; Atrophy; Behavior, Animal; Brain Injury, Chronic; Chromones; Cyclopropanes; Disease Models, Animal; Drug Evaluation, Preclinical; Edaravone; Free Radical Scavengers; Infarction, Middle Cerebral Artery; Injections, Intraperitoneal; Leukotriene Antagonists; Male; Mice; Mice, Inbred ICR; Nerve Degeneration; Quinolines; Rats; Rats, Sprague-Dawley; Sulfides | 2011 |
Cysteinyl leukotriene receptor (CysLT) antagonists decrease pentylenetetrazol-induced seizures and blood-brain barrier dysfunction.
Topics: Acetates; Animals; Anticonvulsants; Blood-Brain Barrier; Brain; Capillary Permeability; Chromones; Cyclopropanes; Dose-Response Relationship, Drug; Immunoglobulin G; Leukocyte Common Antigens; Leukocytes; Leukotriene Antagonists; Leukotriene D4; Male; Mice; Neuroprotective Agents; Pentylenetetrazole; Quinolines; Receptors, Leukotriene; Seizures; SRS-A; Sulfides | 2014 |
The safety of pranlukast and montelukast during the first trimester of pregnancy: A prospective, two-centered cohort study in Japan.
Topics: Abortion, Spontaneous; Acetates; Chromones; Cohort Studies; Cyclopropanes; Female; Humans; Infant, Newborn; Japan; Leukotriene Antagonists; Pregnancy; Pregnancy Outcome; Pregnancy Trimester, First; Premature Birth; Prospective Studies; Quinolines; Sulfides | 2022 |