ono 1078 has been researched along with leukotriene e4 in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (6.25) | 18.7374 |
| 1990's | 6 (37.50) | 18.2507 |
| 2000's | 8 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Abramovitz, M; Austin, CP; Bai, C; Caskey, CT; Chateauneuf, A; Connolly, BM; Coulombe, N; Evans, JF; Figueroa, DJ; Ford-Hutchinson, AW; Greig, GM; Hooks, SB; Hosfield, E; Im, DS; Kargman, S; Liu, Q; Lynch, KR; Metters, KM; O'Neill, GP; Sawyer, N; Stocco, R; Williams, DL; Zeng, Z | 1 |
| Ames, RS; Bergsma, DJ; Buckley, PT; Chambers, J; Dytko, GM; Ellis, C; Elshourbagy, N; Foley, JJ; Halsey, W; Hay, DW; Herrity, NC; Jenkins, O; Muccitelli, RM; Muir, AI; Murdock, PR; Nuthulaganti, P; Sarau, HM; Sathe, G; Schmidt, DB; Wilson, S | 1 |
| Abramovitz, M; Austin, CP; Bellefeuille, JN; Cheng, R; Clements, MK; Coulombe, N; Evans, JF; Figueroa, DJ; George, SR; Heise, CE; Im, DS; Liu, Q; Liu, Y; Lynch, KR; Ma, L; Metters, KM; Nguyen, T; O'Dowd, BF; O'Neill, GP; Sawyer, N; Stocco, R; Williams, DL; Zeng, Z | 1 |
| Baronissi, G; Biagioli, M; Cassiano, C; Catalanotti, B; Conflitti, P; De Luca, P; Fiorillo, B; Fiorucci, S; Limongelli, V; Marchianò, S; Rapacciuolo, P; Roselli, R; Sepe, V; Zampella, A | 1 |
| Aishita, H; Kobayashi, T; Nakagawa, N; Nambu, F; Obata, T; Okada, Y; Terawaki, T | 1 |
| Haranaka, K; Haranaka, R; Iimura, F; Sakurai, A; Satomi, N | 1 |
| Cloud, ML; Fleisch, JH; Marshall, WS | 1 |
| Fujita, M; Kawabata, K; Nakagawa, N; Ohno, H; Takeda, H; Yonetomi, Y | 1 |
| Abe, S; Hashimoto, M; Kaneko, S; Kurokawa, K; Miyazaki, N; Saito, T; Tanaka, H; Teramoto, S | 1 |
| Arakida, Y; Morio, H; Ohga, K; Okada, Y; Suwa, K; Yamada, T; Yokota, M | 1 |
| Abe, M; Hugli, TE; Kamiya, H; Katsuragi, T; Kodani, M; Sakata, N; Takano, Y | 1 |
| Kawano, T; Kohno, S; Matsuse, H; Mitsuta, K; Obase, Y; Shimoda, T; Tomari, SY | 1 |
| Mizutani, N | 1 |
| Furukawa, S; Hasegawa, S; Ichiyama, T; Matsubara, T; Terai, K; Umeda, M | 1 |
| Abe, Y; Hisano, M; Sakai, T; Tsuji, Y | 1 |
| Furukawa, S; Hasegawa, M; Ichiyama, T; Makata, H; Matsubara, T; Ueno, Y | 1 |
2 review(s) available for ono 1078 and leukotriene e4
| Article | Year |
|---|---|
A brief review of preclinical and clinical studies with LY171883 and some comments on newer cysteinyl leukotriene receptor antagonists.
Topics: Acetophenones; Animals; Asthma; Azoles; Bronchi; Chromones; Dicarboxylic Acids; Drug Evaluation; Drug Evaluation, Preclinical; Guinea Pigs; Haplorhini; Humans; Indazoles; Leukotriene E4; Receptors, Leukotriene; Receptors, Prostaglandin; SRS-A; Structure-Activity Relationship; Tetrazoles | 1988 |
[Studies on the experimental allergic rhinitis induced by Japanese cedar pollen--role of cysteinyl leukotrienes in nasal allergic symptoms].
Topics: Allergens; Animals; Bronchial Provocation Tests; Chromones; Cryptomeria; Disease Models, Animal; Guinea Pigs; Humans; Inflammation Mediators; Leukotriene Antagonists; Leukotriene C4; Leukotriene D4; Leukotriene E4; Lipoxygenase Inhibitors; Membrane Proteins; Pollen; Receptors, Leukotriene; Rhinitis, Allergic, Seasonal | 2003 |
1 trial(s) available for ono 1078 and leukotriene e4
| Article | Year |
|---|---|
Leukotriene (LT)-receptor antagonist is more effective in asthmatic patients with a low baseline ratio of urinary LTE4 to 2,3-dinor-6-keto-prostaglandin (PG)F1alpha.
Topics: Adult; Aged; Anti-Asthmatic Agents; Asthma; Chromones; Female; Humans; Leukotriene Antagonists; Leukotriene E4; Male; Middle Aged; Peak Expiratory Flow Rate; Prostaglandins F; Thromboxane B2 | 1999 |
13 other study(ies) available for ono 1078 and leukotriene e4
| Article | Year |
|---|---|
Characterization of the human cysteinyl leukotriene CysLT1 receptor.
Topics: Amino Acid Sequence; Animals; Base Sequence; Blotting, Northern; Chromosome Mapping; Cloning, Molecular; COS Cells; Humans; Leukotriene Antagonists; Leukotriene D4; Lung; Macrophages, Alveolar; Membrane Proteins; Molecular Sequence Data; Muscle, Smooth; Receptors, Leukotriene; Tissue Distribution; Transfection; X Chromosome; Xenopus laevis | 1999 |
Identification, molecular cloning, expression, and characterization of a cysteinyl leukotriene receptor.
Topics: Amino Acid Sequence; Base Sequence; Binding Sites; Biological Transport; Calcium; Cells, Cultured; Cloning, Molecular; Humans; Leukotriene D4; Membrane Proteins; Molecular Sequence Data; Pertussis Toxin; Receptors, Leukotriene; Signal Transduction; Virulence Factors, Bordetella | 1999 |
Characterization of the human cysteinyl leukotriene 2 receptor.
Topics: Adrenal Medulla; Cloning, Molecular; Cysteine; Humans; Leukotriene Antagonists; Leukotriene C4; Leukotriene D4; Leukotriene E4; Leukotrienes; Lung; Membrane Proteins; Models, Molecular; Myocardium; Receptors, Leukotriene; Recombinant Proteins; Sequence Analysis, DNA; Sequence Homology, Amino Acid; SRS-A; Tissue Distribution | 2000 |
Structural Basis for Developing Multitarget Compounds Acting on Cysteinyl Leukotriene Receptor 1 and G-Protein-Coupled Bile Acid Receptor 1.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Humans; Leukotriene D4; Macrophages; Mice; Molecular Docking Simulation; Protein Binding; RAW 264.7 Cells; Receptors, G-Protein-Coupled; Receptors, Leukotriene; Structure-Activity Relationship | 2021 |
In vivo pharmacologic profile of ONO-1078: a potent, selective and orally active peptide leukotriene (LT) antagonist.
Topics: Animals; Antigens, Bacterial; Bordetella pertussis; Bronchoconstriction; Capillary Permeability; Chromones; Guinea Pigs; In Vitro Techniques; Leukotriene Antagonists; Leukotriene E4; Male; SRS-A | 1992 |
Preventive effect of several drugs against Pseudomonas aeruginosa infection and the toxicity of combined tumor necrosis factor with lipopolysaccharide: relationship between lethality and the arachidonic cascade.
Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Antibodies; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Arachidonic Acid; Arachidonic Acids; Cephamycins; Chromones; Drug Synergism; Drugs, Chinese Herbal; Female; Leukotriene Antagonists; Leukotriene E4; Lipopolysaccharides; Mice; Mice, Inbred Strains; Platelet Activating Factor; Polymyxin B; Pseudomonas Infections; Recombinant Proteins; SRS-A; Tumor Necrosis Factor-alpha | 1990 |
Cysteinyl leukotrienes induce nasal symptoms of allergic rhinitis via a receptor-mediated mechanism in guinea pigs.
Topics: Administration, Oral; Airway Resistance; Animals; Anti-Asthmatic Agents; Binding Sites; Chromones; Dose-Response Relationship, Drug; Eosinophils; Guinea Pigs; In Vitro Techniques; Leukotriene Antagonists; Leukotriene C4; Leukotriene D4; Leukotriene E4; Male; Nasal Mucosa; Receptors, Leukotriene; Rhinitis, Allergic, Perennial; Tritium | 1997 |
Effect of combined leukotriene D(4) and thromboxane A(2) receptor antagonist on mediator-controlled resistance in guinea pigs.
Topics: Administration, Oral; Airway Resistance; Animals; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Antigens; Asthma; Benzoquinones; Chromones; Dose-Response Relationship, Drug; Guinea Pigs; Heptanoic Acids; Indomethacin; Leukotriene Antagonists; Leukotriene B4; Leukotriene C4; Leukotriene E4; Lipid Metabolism; Lung; Male; Membrane Proteins; Ovalbumin; Receptors, Leukotriene; Receptors, Thromboxane; Tetrazoles; Thiazoles; Thromboxane B2; Time Factors | 2000 |
Intratracheal administration of anaphylatoxin C5a potentiates antigen-induced pulmonary reactions through the prolonged production of cysteinyl-leukotrienes.
Topics: Airway Resistance; Animals; Antigens; Bile; Chromones; Complement C5a; Complement C5a, des-Arginine; Cysteine; Diphenhydramine; Histamine H1 Antagonists; Hypersensitivity, Immediate; Inflammation Mediators; Injections, Subcutaneous; Intubation, Intratracheal; Leukotriene Antagonists; Leukotriene D4; Leukotriene E4; Leukotrienes; Lung; Male; Membrane Proteins; Ovalbumin; Rats; Rats, Inbred BN; Receptors, Leukotriene; Zymosan | 2000 |
Effects of pranlukast on chemical mediators in induced sputum on provocation tests in atopic and aspirin-intolerant asthmatic patients.
Topics: Adult; Anti-Asthmatic Agents; Aspirin; Asthma; Blood Proteins; Bronchial Provocation Tests; Chromones; Drug Hypersensitivity; Eosinophil Granule Proteins; Eosinophils; Female; Forced Expiratory Volume; Humans; Leukocyte Count; Leukotriene D4; Leukotriene E4; Male; Middle Aged; Ribonucleases; Thromboxane B2 | 2002 |
Pranlukast inhibits NF-kappa B activation in human monocytes/macrophages and T cells.
Topics: Chromones; Cytokines; Dimethyl Sulfoxide; Humans; Interleukin-6; Jurkat Cells; Leukocytes, Mononuclear; Leukotriene Antagonists; Leukotriene C4; Leukotriene D4; Leukotriene E4; Lipopolysaccharides; NF-kappa B; Propionates; Quinolines; Statistics, Nonparametric; U937 Cells | 2003 |
Urinary leukotriene E4 in Henoch-Schonlein purpura.
Topics: Adolescent; Biomarkers; Case-Control Studies; Child; Child, Preschool; Chromones; Female; Glomerulonephritis; Humans; IgA Vasculitis; Leukotriene Antagonists; Leukotriene E4; Male; Statistics, Nonparametric | 2004 |
Cysteinyl leukotrienes induce monocyte chemoattractant protein 1 in human monocytes/macrophages.
Topics: Blotting, Western; Cell Line, Tumor; Chemokine CCL11; Chemokine CCL2; Chemokines, CC; Chromones; Cytokines; Humans; Leukotriene Antagonists; Leukotriene C4; Leukotriene D4; Leukotriene E4; Leukotrienes; Lipopolysaccharide Receptors; Macrophage Colony-Stimulating Factor; Macrophages; Monocytes; Receptors, CCR2; Receptors, Chemokine; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Statistics, Nonparametric; Tumor Necrosis Factor-alpha | 2005 |