ono 1078 has been researched along with leukotriene c4 in 24 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 12 (50.00) | 18.2507 |
| 2000's | 10 (41.67) | 29.6817 |
| 2010's | 1 (4.17) | 24.3611 |
| 2020's | 1 (4.17) | 2.80 |
| Authors | Studies |
|---|---|
| Abramovitz, M; Austin, CP; Bai, C; Caskey, CT; Chateauneuf, A; Connolly, BM; Coulombe, N; Evans, JF; Figueroa, DJ; Ford-Hutchinson, AW; Greig, GM; Hooks, SB; Hosfield, E; Im, DS; Kargman, S; Liu, Q; Lynch, KR; Metters, KM; O'Neill, GP; Sawyer, N; Stocco, R; Williams, DL; Zeng, Z | 1 |
| Ames, RS; Bergsma, DJ; Buckley, PT; Chambers, J; Dytko, GM; Ellis, C; Elshourbagy, N; Foley, JJ; Halsey, W; Hay, DW; Herrity, NC; Jenkins, O; Muccitelli, RM; Muir, AI; Murdock, PR; Nuthulaganti, P; Sarau, HM; Sathe, G; Schmidt, DB; Wilson, S | 1 |
| Abramovitz, M; Austin, CP; Bellefeuille, JN; Cheng, R; Clements, MK; Coulombe, N; Evans, JF; Figueroa, DJ; George, SR; Heise, CE; Im, DS; Liu, Q; Liu, Y; Lynch, KR; Ma, L; Metters, KM; Nguyen, T; O'Dowd, BF; O'Neill, GP; Sawyer, N; Stocco, R; Williams, DL; Zeng, Z | 1 |
| Baronissi, G; Biagioli, M; Cassiano, C; Catalanotti, B; Conflitti, P; De Luca, P; Fiorillo, B; Fiorucci, S; Limongelli, V; Marchianò, S; Rapacciuolo, P; Roselli, R; Sepe, V; Zampella, A | 1 |
| Hikasa, Y; Hori, K; Nishikawa, M; Shimoyama, T; Tanida, N | 1 |
| Kurosawa, M; Miyachi, Y; Tsukagoshi, H; Yodonawa, S | 1 |
| Bian, RL; Chen, LP; Tang, FD; Wang, YC; Wei, EQ | 1 |
| Hosokawa, M; Nakamura, H; Okuma, M; Sakai, M; Taniguchi, T; Tominaga, M; Tsukada, H; Ueda, S | 1 |
| Ashino, Y; Fujimura, S; Hoshikawa, Y; Koike, K; Nishimura, T; Noda, M; Ono, S; Tabata, T; Tanita, T; Ueda, S | 1 |
| Inokuma, S; Ito, K; Kobayashi, S; Matsumura, Y; Mori, A; Okudaira, H; Sugiyama, H; Suko, M; Yoshida, K | 1 |
| Fujita, M; Kawabata, K; Nakagawa, N; Ohno, H; Takeda, H; Yonetomi, Y | 1 |
| Fukuda, M; Kawabata, S; Kohno, S; Nakamura, T; Nakano, R; Noguchi, Y; Oka, M; Soda, H; Terashi, K; Tsukamoto, K | 1 |
| Bian, RL; Liu, JW; Wei, EQ; Zhang, LF; Zhang, WP | 1 |
| Matsui, T; Nakasato, H; Ohrui, T; Sasaki, H; Sekizawa, K; Tamura, G; Yamaya, M | 1 |
| Arakida, Y; Morio, H; Ohga, K; Okada, Y; Suwa, K; Yamada, T; Yokota, M | 1 |
| Hisamatsu, K; Nakajima, M | 1 |
| Capra, V; Nicosia, S; Panigalli, T; Ravasi, S; Rovati, GE | 1 |
| Mizutani, N | 1 |
| Furukawa, S; Hasegawa, S; Ichiyama, T; Matsubara, T; Terai, K; Umeda, M | 1 |
| Ito, R; Miura, K; Odajima, Y; Shimamura, T | 1 |
| Furukawa, S; Hasegawa, M; Ichiyama, T; Makata, H; Matsubara, T; Ueno, Y | 1 |
| Jin, SM; Kim, SR; Lee, KS; Lee, KY; Lee, YC; Min, KH; Park, HS; Park, SJ | 1 |
| Ae, T; Arai, K; Hattori, Y; Majima, M; Mizuguchi, S; Ohno, T; Saeki, T; Saigenji, K | 1 |
| Chebolu, S; Darmani, NA; Ray, AP; Wang, Y | 1 |
1 review(s) available for ono 1078 and leukotriene c4
| Article | Year |
|---|---|
[Studies on the experimental allergic rhinitis induced by Japanese cedar pollen--role of cysteinyl leukotrienes in nasal allergic symptoms].
Topics: Allergens; Animals; Bronchial Provocation Tests; Chromones; Cryptomeria; Disease Models, Animal; Guinea Pigs; Humans; Inflammation Mediators; Leukotriene Antagonists; Leukotriene C4; Leukotriene D4; Leukotriene E4; Lipoxygenase Inhibitors; Membrane Proteins; Pollen; Receptors, Leukotriene; Rhinitis, Allergic, Seasonal | 2003 |
23 other study(ies) available for ono 1078 and leukotriene c4
| Article | Year |
|---|---|
Characterization of the human cysteinyl leukotriene CysLT1 receptor.
Topics: Amino Acid Sequence; Animals; Base Sequence; Blotting, Northern; Chromosome Mapping; Cloning, Molecular; COS Cells; Humans; Leukotriene Antagonists; Leukotriene D4; Lung; Macrophages, Alveolar; Membrane Proteins; Molecular Sequence Data; Muscle, Smooth; Receptors, Leukotriene; Tissue Distribution; Transfection; X Chromosome; Xenopus laevis | 1999 |
Identification, molecular cloning, expression, and characterization of a cysteinyl leukotriene receptor.
Topics: Amino Acid Sequence; Base Sequence; Binding Sites; Biological Transport; Calcium; Cells, Cultured; Cloning, Molecular; Humans; Leukotriene D4; Membrane Proteins; Molecular Sequence Data; Pertussis Toxin; Receptors, Leukotriene; Signal Transduction; Virulence Factors, Bordetella | 1999 |
Characterization of the human cysteinyl leukotriene 2 receptor.
Topics: Adrenal Medulla; Cloning, Molecular; Cysteine; Humans; Leukotriene Antagonists; Leukotriene C4; Leukotriene D4; Leukotriene E4; Leukotrienes; Lung; Membrane Proteins; Models, Molecular; Myocardium; Receptors, Leukotriene; Recombinant Proteins; Sequence Analysis, DNA; Sequence Homology, Amino Acid; SRS-A; Tissue Distribution | 2000 |
Structural Basis for Developing Multitarget Compounds Acting on Cysteinyl Leukotriene Receptor 1 and G-Protein-Coupled Bile Acid Receptor 1.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Humans; Leukotriene D4; Macrophages; Mice; Molecular Docking Simulation; Protein Binding; RAW 264.7 Cells; Receptors, G-Protein-Coupled; Receptors, Leukotriene; Structure-Activity Relationship | 2021 |
Effect of leukotriene C4D4 antagonist on colonic damage induced by intracolonic administration of trinitrobenzene sulfonic acid in rats.
Topics: Animals; Chromones; Colon; Disease Models, Animal; Eicosanoids; Female; Inflammatory Bowel Diseases; Leukotriene C4; Leukotriene D4; Methacrylates; Peroxidase; Phenylpropionates; Rats; Rats, Sprague-Dawley; SRS-A; Thromboxane-A Synthase; Trinitrobenzenesulfonic Acid | 1995 |
Inhibition by a novel peptide leukotriene receptor antagonist ONO-1078 of airway wall thickening and airway hyperresponsiveness to histamine induced by leukotriene C4 or leukotriene D4 in guinea-pigs.
Topics: Airway Resistance; Animals; Bronchial Hyperreactivity; Chromones; Guinea Pigs; Histamine; Image Processing, Computer-Assisted; Infusions, Intravenous; Leukotriene Antagonists; Leukotriene C4; Leukotriene D4; Lung; Male; SRS-A | 1994 |
[Effect of a leukotriene antagonist, ONO-1078, on electric stimulation of vagus (ESV)-induced bronchoconstriction and microvascular leakage in guinea pigs].
Topics: Airway Resistance; Animals; Bronchoconstriction; Capillary Permeability; Chromones; Electric Stimulation; Female; Guinea Pigs; Leukotriene C4; Male; Vagus Nerve | 1994 |
ONO-1078 antagonizes diarrhea-causing changes in ion transport and smooth muscle contraction induced by peptidoleukotrienes in rat and human colon in vitro.
Topics: Adult; Animals; Biological Transport; Chromones; Colon; Diarrhea; Electric Conductivity; Humans; In Vitro Techniques; Intestinal Mucosa; Leukotriene Antagonists; Leukotriene C4; Leukotriene D4; Male; Middle Aged; Muscle Contraction; Muscle, Smooth; Rats; Rats, Wistar | 1996 |
[Role of peptide leukotrienes in monocrotaline-induced lung disease].
Topics: Animals; Chromones; Hypertrophy, Right Ventricular; Leukotriene C4; Male; Monocrotaline; Pulmonary Artery; Rats; Rats, Sprague-Dawley | 1995 |
[Inhibitory effect of ONO-1078, a novel leukotriene receptor antagonist, on human peripheral blood eosinophils].
Topics: Asthma; Blood Proteins; Cells, Cultured; Chromones; Depression, Chemical; Eosinophil Granule Proteins; Eosinophils; Female; Humans; Leukotriene Antagonists; Leukotriene C4; Male; Ribonucleases | 1996 |
Cysteinyl leukotrienes induce nasal symptoms of allergic rhinitis via a receptor-mediated mechanism in guinea pigs.
Topics: Administration, Oral; Airway Resistance; Animals; Anti-Asthmatic Agents; Binding Sites; Chromones; Dose-Response Relationship, Drug; Eosinophils; Guinea Pigs; In Vitro Techniques; Leukotriene Antagonists; Leukotriene C4; Leukotriene D4; Leukotriene E4; Male; Nasal Mucosa; Receptors, Leukotriene; Rhinitis, Allergic, Perennial; Tritium | 1997 |
A leukotriene receptor antagonist, ONO-1078, modulates drug sensitivity and leukotriene C4 efflux in lung cancer cells expressing multidrug resistance protein.
Topics: Adenocarcinoma; ATP-Binding Cassette Transporters; Carcinoma, Squamous Cell; Chromones; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Flow Cytometry; Fluoresceins; Fluorescent Dyes; Humans; Leukotriene Antagonists; Leukotriene C4; Lung Neoplasms; Multidrug Resistance-Associated Proteins; Tumor Cells, Cultured; Vincristine | 1998 |
Effect of ONO-1078, a leukotriene antagonist, on capsaicin- and substance P-induced bronchoconstriction and airway microvascular leakage in guinea pigs.
Topics: Animals; Bronchi; Bronchoconstriction; Capsaicin; Chromones; Female; Guinea Pigs; In Vitro Techniques; Leukotriene C4; Male; Muscle Contraction; Muscle, Smooth; Substance P | 1996 |
Prevention of severe premenstrual asthma attacks by leukotriene receptor antagonist.
Topics: Adolescent; Adult; Anti-Asthmatic Agents; Asthma; Chromones; Cytokines; Female; Histamine; Humans; Leukotriene Antagonists; Leukotriene B4; Leukotriene C4; Mast Cells; Menstruation; Peak Expiratory Flow Rate; T-Lymphocytes | 1999 |
Effect of combined leukotriene D(4) and thromboxane A(2) receptor antagonist on mediator-controlled resistance in guinea pigs.
Topics: Administration, Oral; Airway Resistance; Animals; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Antigens; Asthma; Benzoquinones; Chromones; Dose-Response Relationship, Drug; Guinea Pigs; Heptanoic Acids; Indomethacin; Leukotriene Antagonists; Leukotriene B4; Leukotriene C4; Leukotriene E4; Lipid Metabolism; Lung; Male; Membrane Proteins; Ovalbumin; Receptors, Leukotriene; Receptors, Thromboxane; Tetrazoles; Thiazoles; Thromboxane B2; Time Factors | 2000 |
Pranlukast protects leukotriene C4- and D4-induced epithelial cell impairment of the nasal mucosa in vitro.
Topics: Adult; Cells, Cultured; Chromones; Cilia; Humans; Kinetics; Leukotriene Antagonists; Leukotriene C4; Leukotriene D4; Male; Nasal Mucosa; Time Factors | 2000 |
Pharmacological differences among CysLT(1) receptor antagonists with respect to LTC(4) and LTD(4) in human lung parenchyma.
Topics: Acetates; Anti-Asthmatic Agents; Binding, Competitive; Chromones; Cyclopropanes; Humans; Kinetics; Leukotriene Antagonists; Leukotriene C4; Leukotriene D4; Membrane Proteins; Quinolines; Receptors, Leukotriene; Sulfides | 2002 |
Pranlukast inhibits NF-kappa B activation in human monocytes/macrophages and T cells.
Topics: Chromones; Cytokines; Dimethyl Sulfoxide; Humans; Interleukin-6; Jurkat Cells; Leukocytes, Mononuclear; Leukotriene Antagonists; Leukotriene C4; Leukotriene D4; Leukotriene E4; Lipopolysaccharides; NF-kappa B; Propionates; Quinolines; Statistics, Nonparametric; U937 Cells | 2003 |
[Effect of pranlukast on histamine release and leukotriene c4 (ltc4) generation from human peripheral basophils].
Topics: Basophils; Chromones; Histamine Release; Humans; Leukotriene Antagonists; Leukotriene C4 | 2004 |
Cysteinyl leukotrienes induce monocyte chemoattractant protein 1 in human monocytes/macrophages.
Topics: Blotting, Western; Cell Line, Tumor; Chemokine CCL11; Chemokine CCL2; Chemokines, CC; Chromones; Cytokines; Humans; Leukotriene Antagonists; Leukotriene C4; Leukotriene D4; Leukotriene E4; Leukotrienes; Lipopolysaccharide Receptors; Macrophage Colony-Stimulating Factor; Macrophages; Monocytes; Receptors, CCR2; Receptors, Chemokine; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Statistics, Nonparametric; Tumor Necrosis Factor-alpha | 2005 |
Cysteinyl leukotriene upregulates IL-11 expression in allergic airway disease of mice.
Topics: Acetates; Animals; Bronchoalveolar Lavage Fluid; Cells, Cultured; Chromones; Collagen; Cyclopropanes; Epithelial Cells; Female; Interleukin-11; Interleukin-13; Interleukin-4; Leukotriene Antagonists; Leukotriene C4; Leukotriene D4; Lung; Mice; Mice, Inbred C57BL; Nitriles; Ovalbumin; Quinolines; Respiratory Hypersensitivity; RNA, Messenger; Sulfides; Sulfones; Transcription Factor RelA | 2007 |
Gastric mucosal protection against ethanol by EP2 and EP4 signaling through the inhibition of leukotriene C4 production.
Topics: Animals; Arachidonate 5-Lipoxygenase; Benzoquinones; Chromones; Dinoprostone; Dose-Response Relationship, Drug; Ethanol; Gastric Mucosa; Immunohistochemistry; Leukotriene Antagonists; Leukotriene C4; Lipoxygenase Inhibitors; Male; Perfusion; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP3 Subtype; Receptors, Prostaglandin E, EP4 Subtype; Signal Transduction; Time Factors; Vasoconstriction; Vasoconstrictor Agents; Venules | 2008 |
Pranlukast prevents cysteinyl leukotriene-induced emesis in the least shrew (Cryptotis parva).
Topics: Animals; Chromones; Cysteine; Dose-Response Relationship, Drug; Eulipotyphla; Female; Immunohistochemistry; Injections; Leukotriene C4; Leukotrienes; Male; Proto-Oncogene Proteins c-fos; SRS-A; Vomiting | 2010 |