ono 1078 has been researched along with fpl 55712 in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (15.38) | 18.7374 |
| 1990's | 11 (84.62) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Krell, RD; Shaw, A | 1 |
| Brooks, CD; Summers, JB | 1 |
| Onogi, K; Tamura, M; Timmerman, H; Tohma, T; Wada, Y; Zhang, MQ; Zwaagstra, ME | 1 |
| Aishita, H; Kobayashi, T; Nakagawa, N; Nambu, F; Obata, T; Okada, Y; Terawaki, T | 1 |
| Ando, M; Araki, S; Honda, I; Kawano, O; Kohrogi, H; Sugimoto, M; Yamaguchi, T | 1 |
| Aishita, H; Motoishi, M; Nakagawa, N; Obata, T; Okada, Y; Terawaki, T | 1 |
| Ishii, A; Miyamoto, T; Mizushima, Y; Motoishi, M; Nakagawa, T; Nambu, F; Shida, T; Yui, Y | 1 |
| Cloud, ML; Fleisch, JH; Marshall, WS | 1 |
| Horiba, M; Kohno, S; Nabe, T; Ohata, K; Saeki, Y; Tanpo, T; Yamamura, H | 1 |
| Aishita, H; Nakagawa, N; Obata, T; Okada, Y; Terawaki, T | 1 |
| Aishita, H; Furuya, T; Kobayashi, T; Muryobayashi, K; Nakagawa, N; Nambu, F; Obata, T; Okada, Y; Sawada, M; Terawaki, T | 1 |
| Bernstein, PR | 1 |
| Arai, Y; Katsube, N; Konno, M; Kosuge, S; Miyamoto, T; Nakai, H; Obata, T; Okegawa, T; Sakuyama, S; Toda, M | 1 |
4 review(s) available for ono 1078 and fpl 55712
| Article | Year |
|---|---|
Peptide leukotrienes: current status of research.
Topics: Acetophenones; Humans; Leukotriene Antagonists; Leukotrienes; Molecular Structure; Peptides; Receptors, Immunologic; Receptors, Leukotriene; Tetrazoles | 1991 |
Modulators of leukotriene biosynthesis and receptor activation.
Topics: 5-Lipoxygenase-Activating Proteins; Animals; Carrier Proteins; Forecasting; Humans; Leukotriene B4; Leukotrienes; Lipoxygenase Inhibitors; Membrane Proteins; Molecular Structure; Receptors, Leukotriene | 1996 |
A brief review of preclinical and clinical studies with LY171883 and some comments on newer cysteinyl leukotriene receptor antagonists.
Topics: Acetophenones; Animals; Asthma; Azoles; Bronchi; Chromones; Dicarboxylic Acids; Drug Evaluation; Drug Evaluation, Preclinical; Guinea Pigs; Haplorhini; Humans; Indazoles; Leukotriene E4; Receptors, Leukotriene; Receptors, Prostaglandin; SRS-A; Structure-Activity Relationship; Tetrazoles | 1988 |
Chemistry and structure--activity relationships of leukotriene receptor antagonists.
Topics: Acetates; Anti-Asthmatic Agents; Biological Availability; Chromones; Cyclopropanes; Indoles; Leukotriene Antagonists; Leukotrienes; Lipoxygenase Inhibitors; Phenylcarbamates; Quinolines; SRS-A; Structure-Activity Relationship; Sulfides; Sulfonamides; Tosyl Compounds | 1998 |
1 trial(s) available for ono 1078 and fpl 55712
| Article | Year |
|---|---|
Effect of leukotriene antagonist on experimental and clinical bronchial asthma.
Topics: Allergens; Anaphylaxis; Animals; Asthma; Bronchi; Bronchial Provocation Tests; Chromones; Drug Evaluation; Drug Evaluation, Preclinical; Dust; Guinea Pigs; Histamine; Humans; Immunization, Passive; Indomethacin; Male; Ovalbumin; Pyrilamine; SRS-A | 1991 |
8 other study(ies) available for ono 1078 and fpl 55712
| Article | Year |
|---|---|
Synthesis and structure-activity relationships of carboxylated chalcones: a novel series of CysLT1 (LTD4) receptor antagonists.
Topics: Animals; Chalcone; Guinea Pigs; Ileum; In Vitro Techniques; Leukotriene Antagonists; Lung; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Membrane Proteins; Muscle Contraction; Receptors, Leukotriene; Structure-Activity Relationship; Trachea | 1997 |
In vivo pharmacologic profile of ONO-1078: a potent, selective and orally active peptide leukotriene (LT) antagonist.
Topics: Animals; Antigens, Bacterial; Bordetella pertussis; Bronchoconstriction; Capillary Permeability; Chromones; Guinea Pigs; In Vitro Techniques; Leukotriene Antagonists; Leukotriene E4; Male; SRS-A | 1992 |
A novel leukotriene antagonist, ONO-1078, inhibits and reverses human bronchial contraction induced by leukotrienes C4 and D4 and antigen in vitro.
Topics: Antigens; Bronchi; Bronchoconstriction; Chromones; Female; Humans; In Vitro Techniques; Male; Pyrilamine; SRS-A | 1992 |
In vitro antagonism of ONO-1078, a newly developed anti-asthma agent, against peptide leukotrienes in isolated guinea pig tissues.
Topics: Animals; Arachidonate 5-Lipoxygenase; Asthma; Binding, Competitive; Chromones; Guinea Pigs; In Vitro Techniques; Leukotriene Antagonists; Lung; Male; Membranes; Prostaglandin-Endoperoxide Synthases; Radioligand Assay; SRS-A; Thromboxane-A Synthase; Trachea | 1992 |
Inhibitory effect of ONO-1078 on specific binding of peptide leukotrienes to human lung crude membrane.
Topics: Cell Membrane; Chromones; Cysteine; gamma-Glutamyltransferase; Glycine; Humans; Isoxazoles; Leukotriene D4; Lung; Protein Binding; SRS-A | 1994 |
Inhibitory effect of a peptide leukotriene antagonist ONO-1078 on LTD4- and antigen-induced thromboxane B2 production in guinea pig lungs.
Topics: Animals; Antigens; Bordetella pertussis; Chromones; Dose-Response Relationship, Drug; Guinea Pigs; Indomethacin; Kinetics; Lung; Male; Methacrylates; Ovalbumin; SRS-A; Thromboxane B2; Thromboxane-A Synthase | 1993 |
Effect of a peptide leukotriene receptor antagonist, ONO-1078, on guinea-pig models of asthma.
Topics: Acetylcholine; Acute-Phase Reaction; Animals; Asthma; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Bronchodilator Agents; Chromones; Disease Models, Animal; Guinea Pigs; Hypersensitivity; Immunization; Male; Ovalbumin; Phthalazines; Pulmonary Eosinophilia; Pyrilamine; SRS-A | 1993 |
New potent antagonists of leukotrienes C4 and D4. 1. Synthesis and structure-activity relationships.
Topics: Animals; Bronchodilator Agents; Cinnamates; Guinea Pigs; Ileum; In Vitro Techniques; Magnetic Resonance Spectroscopy; Mass Spectrometry; Muscle Contraction; ortho-Aminobenzoates; SRS-A; Structure-Activity Relationship | 1988 |