Page last updated: 2024-08-16

ono 1078 and cysteine

ono 1078 has been researched along with cysteine in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (33.33)18.2507
2000's9 (50.00)29.6817
2010's3 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Horiba, M; Kohno, S; Nabe, T; Ohata, K; Saeki, Y; Tanpo, T; Yamamura, H1
Asakura, K; Kataura, A; Narita, S; Shirasaki, H1
Khawaja, AM; Liu, YC; Rogers, DF1
Aze, Y; Fujita, M; Kawabata, K; Ohno, H; Shimouchi, K; Takeda, H; Yonetomi, Y1
Abe, M; Katsuragi, T; Kodani, M; Sakata, N; Sakurada, T1
Chung, KF; Hisada, T; Nasuhara, Y; Salmon, M1
Abe, M; Hugli, TE; Kamiya, H; Katsuragi, T; Kodani, M; Sakata, N; Takano, Y1
Abo, M; Fujimura, M; Hashimoto, T; Kamio, Y; Katayama, N; Kita, T; Myou, S; Nakao, S; Nishitsuji, M; Nomura, S; Yoshimi, Y1
Kawai, T; Kohno, S; Miura, M; Nabe, T; Yamashita, K1
Amakawa, K; Matsumaru, A; Terashima, T; Yamaguchi, K1
Fukushima, C; Kawano, T; Kohno, S; Kondo, Y; Machida, I; Matsuse, H; Mitsuta, K; Obase, Y; Saeki, S; Shimoda, T; Tomari, S1
Dohi, M; Nakagome, K; Okunishi, K; Tanaka, R; Yamamoto, K1
Tokita, K; Uchida, Y; Yamamoto, T1
Furukawa, S; Hasegawa, M; Hashimoto, K; Ichiyama, T; Kajimoto, M; Matsubara, T1
Akamatsu, K; Hirano, T; Ichikawa, T; Ichinose, M; Koarai, A; Matsunaga, K; Minakata, Y; Sugiura, H; Yanagisawa, S1
Chebolu, S; Darmani, NA; Ray, AP; Wang, Y1
Fukano, R; Furukawa, S; Hasegawa, S; Hashimoto, K; Hirano, R; Ichiyama, T; Suzuki, Y1
Kohno, S; Matsuse, H1

Reviews

1 review(s) available for ono 1078 and cysteine

ArticleYear
Leukotriene receptor antagonists pranlukast and montelukast for treating asthma.
    Expert opinion on pharmacotherapy, 2014, Volume: 15, Issue:3

    Topics: Acetates; Animals; Anti-Asthmatic Agents; Asthma; Chromones; Cyclopropanes; Cysteine; Humans; Leukotriene Antagonists; Leukotrienes; Quinolines; Sulfides

2014

Trials

2 trial(s) available for ono 1078 and cysteine

ArticleYear
Effect of a cysteinyl leukotriene antagonist, pranlukast hydrate, on acetaldehyde-induced bronchoconstriction in asthmatic patients.
    Prostaglandins, leukotrienes, and essential fatty acids, 2001, Volume: 65, Issue:1

    Topics: Acetaldehyde; Adult; Asthma; Bronchoconstriction; Chromones; Cross-Over Studies; Cysteine; Double-Blind Method; Female; Humans; Leukotriene Antagonists; Leukotrienes; Male; Middle Aged; Placebos

2001
Molecular mechanism of the additive effects of leukotriene modifier in asthmatic patients receiving steroid therapy.
    Allergology international : official journal of the Japanese Society of Allergology, 2009, Volume: 58, Issue:1

    Topics: Acetates; Administration, Inhalation; Adrenal Cortex Hormones; Adult; Asthma; Chemokine CCL5; Chromones; Cyclopropanes; Cysteine; Cytokines; Drug Synergism; Female; Forced Expiratory Volume; Humans; Leukotriene Antagonists; Leukotrienes; Male; Middle Aged; Quinolines; Sulfides

2009

Other Studies

15 other study(ies) available for ono 1078 and cysteine

ArticleYear
Inhibitory effect of ONO-1078 on specific binding of peptide leukotrienes to human lung crude membrane.
    Prostaglandins, leukotrienes, and essential fatty acids, 1994, Volume: 51, Issue:3

    Topics: Cell Membrane; Chromones; Cysteine; gamma-Glutamyltransferase; Glycine; Humans; Isoxazoles; Leukotriene D4; Lung; Protein Binding; SRS-A

1994
Effects of a cysteinyl leukotriene antagonist, ONO-1078 (pranlukast), on total airway resistance after antigen challenge in sensitized guinea pigs.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1997, Volume: 46, Issue:4

    Topics: Administration, Topical; Airway Resistance; Animals; Anti-Asthmatic Agents; Chromones; Cysteine; Disease Models, Animal; Eosinophils; Guinea Pigs; Leukotriene Antagonists; Nasal Mucosa; Ovalbumin; Plethysmography; Rhinitis, Allergic, Perennial; Serine Proteinase Inhibitors

1997
Effects of the cysteinyl leukotriene receptor antagonists pranlukast and zafirlukast on tracheal mucus secretion in ovalbumin-sensitized guinea-pigs in vitro.
    British journal of pharmacology, 1998, Volume: 124, Issue:3

    Topics: Adenosine Triphosphate; Animals; Anti-Asthmatic Agents; Binding, Competitive; Chromones; Cysteine; Guinea Pigs; Hypersensitivity; In Vitro Techniques; Indoles; Leukotriene Antagonists; Leukotriene D4; Male; Membrane Proteins; Mucus; Ovalbumin; Passive Cutaneous Anaphylaxis; Phenylcarbamates; Receptors, Leukotriene; Sulfates; Sulfonamides; Sulfur Radioisotopes; Tosyl Compounds; Trachea

1998
Involvement of cysteinyl leukotrienes in biphasic increase of nasal airway resistance of antigen-induced rhinitis in guinea pigs.
    European journal of pharmacology, 1999, Mar-26, Volume: 369, Issue:3

    Topics: Airway Resistance; Animals; Chromones; Cysteine; Disease Models, Animal; Guinea Pigs; Leukotriene Antagonists; Leukotrienes; Male; Nasal Mucosa; Ovalbumin; Rhinitis, Allergic, Perennial; Serine Proteinase Inhibitors

1999
Synergistic effects of pranlukast and leukotriene B4 receptor antagonist on antigen-induced pulmonary reaction.
    European journal of pharmacology, 1999, Apr-09, Volume: 370, Issue:2

    Topics: Animals; Anti-Asthmatic Agents; Antigens; Chromones; Cysteine; Drug Synergism; Immunosuppressive Agents; Injections, Spinal; Leukotriene Antagonists; Leukotrienes; Lung; Male; Phenylpropionates; Rats; Rats, Inbred BN; Receptors, Leukotriene B4

1999
Cysteinyl-leukotrienes partly mediate eotaxin-induced bronchial hyperresponsiveness and eosinophilia in IL-5 transgenic mice.
    American journal of respiratory and critical care medicine, 1999, Volume: 160, Issue:2

    Topics: Acetylcholine; Airway Resistance; Animals; Benzofurans; Bronchial Hyperreactivity; Bronchial Provocation Tests; Chemokine CCL11; Chemokines, CC; Chemotactic Factors, Eosinophil; Chromones; Cysteine; Cytokines; Eosinophilia; Eosinophils; Interleukin-5; Leukocyte Count; Leukotriene Antagonists; Leukotrienes; Lipoxygenase Inhibitors; Mice; Mice, Inbred CBA; Mice, Transgenic; Urea

1999
Intratracheal administration of anaphylatoxin C5a potentiates antigen-induced pulmonary reactions through the prolonged production of cysteinyl-leukotrienes.
    Immunopharmacology, 2000, Volume: 49, Issue:3

    Topics: Airway Resistance; Animals; Antigens; Bile; Chromones; Complement C5a; Complement C5a, des-Arginine; Cysteine; Diphenhydramine; Histamine H1 Antagonists; Hypersensitivity, Immediate; Inflammation Mediators; Injections, Subcutaneous; Intubation, Intratracheal; Leukotriene Antagonists; Leukotriene D4; Leukotriene E4; Leukotrienes; Lung; Male; Membrane Proteins; Ovalbumin; Rats; Rats, Inbred BN; Receptors, Leukotriene; Zymosan

2000
Cysteinyl leukotriene-dependent interleukin-5 production leading to eosinophilia during late asthmatic response in guinea-pigs.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2002, Volume: 32, Issue:4

    Topics: Animals; Asthma; Cell Survival; Chromones; Cysteine; Eosinophilia; Guinea Pigs; Interleukin-5; Kinetics; Leukotriene Antagonists; Leukotrienes; Male; Membrane Proteins; Ovalbumin; Pulmonary Eosinophilia; Receptors, Leukotriene; Thiazoles

2002
Correlation between cysteinyl leukotriene release from leukocytes and clinical response to a leukotriene inhibitor.
    Chest, 2002, Volume: 122, Issue:5

    Topics: Adolescent; Adult; Asthma; Chromones; Cysteine; Female; Humans; Inflammation Mediators; Leukocytes; Leukotriene Antagonists; Leukotrienes; Male; Middle Aged

2002
Cysteinyl leukotrienes induce nuclear factor kappa b activation and RANTES production in a murine model of asthma.
    The Journal of allergy and clinical immunology, 2003, Volume: 112, Issue:2

    Topics: Animals; Antigens, Dermatophagoides; Asthma; Bronchial Hyperreactivity; Bronchitis; Chemokine CCL5; Chromones; Cysteine; Cytokines; Female; Inflammation Mediators; Leukotriene Antagonists; Leukotriene D4; Leukotrienes; Lung; Mice; Mice, Inbred BALB C; Monocytes; NF-kappa B; Transcription Factor RelA

2003
A novel role of cysteinyl leukotrienes to promote dendritic cell activation in the antigen-induced immune responses in the lung.
    Journal of immunology (Baltimore, Md. : 1950), 2004, Nov-15, Volume: 173, Issue:10

    Topics: Adjuvants, Immunologic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antigens; Arachidonate 5-Lipoxygenase; Bronchial Hyperreactivity; CD4-Positive T-Lymphocytes; Cells, Cultured; Chromones; Cysteine; Dendritic Cells; Inflammation; Leukotriene Antagonists; Leukotrienes; Lung; Male; Membrane Proteins; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Ovalbumin; Receptors, Leukotriene; Th1 Cells

2004
Roles of leukocytosis and cysteinyl leukotriene in polymorphonuclear leukocyte-dependent plasma extravasation.
    Journal of leukocyte biology, 2006, Volume: 80, Issue:6

    Topics: Adrenergic beta-Antagonists; Animals; Arachidonate 5-Lipoxygenase; Bradykinin; Bradykinin B2 Receptor Antagonists; Capillary Permeability; Chromones; Complement C5a; Cysteine; Granulocyte Colony-Stimulating Factor; Guinea Pigs; Humans; Immunologic Factors; Indoles; Leukocytosis; Leukotriene Antagonists; Leukotrienes; Lipoxygenase Inhibitors; Neutrophils; Receptor, Bradykinin B2; Recombinant Proteins; Zymosan

2006
Cysteinyl leukotrienes enhance tumour necrosis factor-alpha-induced matrix metalloproteinase-9 in human monocytes/macrophages.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2007, Volume: 37, Issue:4

    Topics: Anti-Asthmatic Agents; Chromones; Cysteine; Drug Synergism; Gene Expression Regulation, Enzymologic; Humans; Leukotriene Antagonists; Leukotrienes; Macrophages; Matrix Metalloproteinase 9; Membrane Proteins; Monocytes; Receptors, Leukotriene; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

2007
Pranlukast prevents cysteinyl leukotriene-induced emesis in the least shrew (Cryptotis parva).
    European journal of pharmacology, 2010, Feb-25, Volume: 628, Issue:1-3

    Topics: Animals; Chromones; Cysteine; Dose-Response Relationship, Drug; Eulipotyphla; Female; Immunohistochemistry; Injections; Leukotriene C4; Leukotrienes; Male; Proto-Oncogene Proteins c-fos; SRS-A; Vomiting

2010
Functional expression of cysteinyl leukotriene receptors on human platelets.
    Platelets, 2010, Volume: 21, Issue:4

    Topics: Animals; Blood Platelets; Cell Line; Chemokine CCL5; Chromones; Cysteine; Humans; Leukotriene Antagonists; Leukotrienes; Receptors, Leukotriene

2010