ondansetron has been researched along with tropisetron in 157 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (3.82) | 18.7374 |
| 1990's | 86 (54.78) | 18.2507 |
| 2000's | 44 (28.03) | 29.6817 |
| 2010's | 16 (10.19) | 24.3611 |
| 2020's | 5 (3.18) | 2.80 |
| Authors | Studies |
|---|---|
| Baker, R; Beer, M; Herbert, R; Kneen, C; Moseley, J; Saunders, J; Seward, EM; Stanton, J; Stevenson, GI; Swain, CJ | 1 |
| Bloomquist, W; Cohen, ML; Lacefield, WB; Pfeifer, W; Robertson, DW; Simon, RL | 1 |
| McLean, S; Nagel, AA; Rizzi, JP; Rosen, T; Seeger, T | 1 |
| Daffeh, JB; Ganong, AH; Guarino, K; Heym, J; Ives, JL; McLean, S; Nagel, AA; Nowakowski, JT; Rizzi, JP; Rosen, T | 1 |
| Bryce, D; Chalabi, PM; Furman, J; Guarino, KJ; Ives, JL; McLean, S; Nagel, AA; Rosen, T; Roth, RW; Seeger, TF | 1 |
| Bloomquist, W; Cohen, ML; Reid, LR; Robertson, DW; Schenck, K; Wong, DT | 1 |
| Daffeh, J; Guarino, K; Heym, J; McLean, S; Nagel, AA; Nowakowski, J; Rizzi, J; Rosen, T; Seeger, T; Vincent, LA | 1 |
| Carr, AA; Hibert, MF; Hoffmann, R; Miller, RC | 1 |
| Berger, J; Bonhaus, DW; Clark, RD; Eglen, RM; Kowalczyk, BA; Lee, CH; Michel, AD; Miller, AB; Repke, DB; Weinhardt, KK | 1 |
| Arrigoni, C; Bolis, G; Caccia, C; Dho, L; Heidempergher, F; McArthur, R; Pillan, A; Pinciroli, V; Vaghi, F; Varasi, M | 1 |
| Bourguignon, JJ; Didier, B; Hoffmann, R; Rival, Y; Rybaltchenko, V; Wermuth, CG | 1 |
| Gordon, JC; Gurley, D; Lanthorn, T; Loch, J; Mack, RA; Macor, JE; Mullen, G; Tran, O; Wright, N | 1 |
| Papke, RL; Porter Papke, JK; Rose, GM | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC | 1 |
| Candura, SM; Coccini, T; Manzo, L; Onori, L; Rizzi, CA; Tonini, M | 1 |
| North, RA; Shen, KZ; Sugita, S | 1 |
| Jørgensen, H; Knigge, U; Warberg, J | 2 |
| Adrien, J; Franc, B; Haj-Dahmane, S; Hamon, M; Jolas, T; Lanfumey, L; Tissier, MH | 1 |
| Jantunen, IT; Johansson, RT; Kataja, VV | 1 |
| Gozlan, H; Martin, P; Puech, AJ | 1 |
| Andrioli, GC; Cavazzani, P; Maura, G; Raiteri, M | 1 |
| Moser, PC | 1 |
| Andrews, PL; Bhandari, P | 1 |
| Higgins, GA; Jones, BJ; Oakley, NR; Tyers, MB | 1 |
| de Mulder, PH; Seynaeve, C; Verweij, J | 1 |
| Jantunen, I; Johansson, R | 1 |
| Bunce, KT; Elswood, CJ; Humphrey, PP | 1 |
| Itoh, Z; Iwanaga, Y; Mizumoto, A; Yoshida, N | 1 |
| Gandara, DR; Hesketh, PJ | 1 |
| Coffman, WJ; Cohen, ML; Wilson, H | 1 |
| Surprenant, A; Vanner, S | 1 |
| Moss, HE; Sanger, GJ | 1 |
| Brown, GW; Butcher, ME; Kidgell, AE | 1 |
| Bloomquist, W; Cohen, ML; Gidda, JS; Lacefield, W | 1 |
| Costall, B; Kelly, ME; Naylor, RJ; Onaivi, ES; Tyers, MB | 1 |
| Dyche, J; Giordano, J | 1 |
| Galligan, JJ; North, RA; Tonini, M | 1 |
| Ito, A; Ito, T; Iwanaga, H; Karasawa, T; Mizumoto, A; Yoshida, N | 1 |
| Blaney, FE; Edge, C; Phippen, RW | 1 |
| Ramadori, G; Schwörer, H | 1 |
| Allison, K; Arnold, B; Greenshaw, AJ; Ivanová, S; Paetsch, PR; Paslawski, T | 1 |
| Perez, EA | 1 |
| Münke, H; Ramadori, G; Schwörer, H; Stöckmann, F | 1 |
| Carles, P; de Bruijn, KM; Fournel, P; Kleisbauer, JP; Loria-Kanza, Y; Marty, M; Simonetta, C; Vergnenegre, A | 1 |
| Gietzen, DW; Rogers, QR; Terry-Nathan, VR | 1 |
| de Boer, M; de Wit, R; Stoter, G; Verweij, J | 1 |
| Ayrton, AD; Baldwin, SJ; Bloomer, JC; Chenery, RJ; Clarke, SE; Smith, GJ | 1 |
| Bidziński, A; Kostowski, W; Pałejko, W; Płaźnik, A; Stefański, R | 1 |
| Mizutani, M; Neya, T; Yamasato, T | 1 |
| Del Favero, A; Roila, F; Tonato, M | 1 |
| Gietzen, DW; Jiang, JC | 1 |
| Costall, B; Naylor, RJ | 1 |
| Beubler, E; Gamse, R; Schirgi-Degen, A | 1 |
| Hui, SC; Ogle, CW; Sevilla, EL | 1 |
| Abraham, C; Giesen-Crouse, E; Lacoste, JM; Laubie, M; Malen, C; Morain, P | 1 |
| Grahame-Smith, DG; Leslie, RA; Pei, Q; Zetterström, T | 1 |
| Aapro, MS | 2 |
| Flander, MK; Jantunen, IT; Kataja, VV; Muhonen, TT; Teerenhovi, L | 1 |
| Blackburn, TP; Grahame-Smith, DG; Leslie, RA; Newberry, NR; Sprosen, TS; Watkins, CJ | 1 |
| Paudice, P; Raiteri, M; Vallebuona, F | 1 |
| Barrett, JE; Critchett, D; Hu, W; Sokol, PT; Solomon, AJ; Toral, J; Ziai, MR | 1 |
| Olver, IN | 2 |
| de Bruijn, KM; Kataja, V | 1 |
| Bianchi, A; Curreli, L; Ghiani, M; Macciò, A; Mantovani, G; Proto, E; Santona, MC | 1 |
| Hickok, JT; Morrow, GR; Rosenthal, SN | 1 |
| Barbato, F; La Rotonda, MI; Quaglia, F | 1 |
| Galindo, JR | 1 |
| Alon, E; Biro, P | 1 |
| David, M; Dow, J; Sanwald, P | 1 |
| Ali, Z; Barasi, S; Kozlov, A; Wu, G | 1 |
| Hong, E; Meneses, A | 1 |
| Ionta, MT; Massidda, B | 1 |
| Attia, M; Channa, AB; el Bakry, AK; el Gammal, K; el Gammal, M; Elhattab, YS; Jaroudi, R; Khoshim, MH; Naguib, M; Saddique, A | 1 |
| Cervo, L; Pozzi, L; Samanin, R | 1 |
| Masek, K; Ruzicka, V; Sevcík, J; Slánsky, J | 1 |
| Teixeira, GM; Tremont-Lukats, IW | 1 |
| Kobayashi, S; Kumai, T; Nakura, H; Tanaka, M; Tateishi, T; Watanabe, M | 1 |
| Grondahi, ML; Hansen, MB; Jensen, GM; Skadhauge, E | 1 |
| Dahl, SG; Junien, JL; Langlois, A; Pascaud, X; Rivière, PJ | 1 |
| Borsini, F; Pitsikas, N | 1 |
| Kandasamy, SB | 1 |
| González, AA; Puig, MM | 1 |
| Basurto, C; Ciccarese, G; Palladino, MA; Roila, F | 1 |
| Masek, K; Růzicka, V; Sevcík, J; Slánský, J; Smejkal, J | 1 |
| Dick, W; Färber, L; Hennes, HJ; Scholz, J; Schulte am Esch, J; Schweiger, C; Steinfath, M | 1 |
| Maksay, G | 1 |
| Baltali, E; Barişta, I; Ozişik, Y; Tekuzman, G; Yalçin, S | 1 |
| Ala-Kokko, TI; Jokela, R; Koivuranta, M; Ranta, P | 1 |
| Ng, KF; Pun, TC; Tang, GW; Tsui, SL; Wong, LC; Yang, JC | 1 |
| Papadimitriou, J; Papadimitriou, L; Petropoulos, G; Pourgezi, T; Vassiliou, J | 1 |
| Bacci, G; Beghelli, C; Biolchini, A; Ferrari, S; Forni, C; Loro, L; Mazzei, T; Puggioli, C; Simoni, P; Strazzari, S; Tremosini, M | 1 |
| Alkiş, N; Kartum, A; Oge, A; Oge, O | 1 |
| Chan, R; Chua, DT; Foo, YC; Kwok, CC; Kwong, DL; Sham, JS; Yue, A | 1 |
| Akutagawa, N; Ishioka, S; Ito, E; Kiya, T; Kudo, R; Sagae, S; Saito, T; Sugimura, M; Umemura, K | 1 |
| Barrajon, E; de las Peñas, R | 1 |
| Färber, L; Späth, M; Welzel, D | 1 |
| Bernand, S; Burg, G; Dummer, R; Scheidegger, EP | 1 |
| Klener, P; Procházka, B; Slabý, J; Trnený, M | 1 |
| Araújo Pereira, ME; Carmo, JA; Juncal, C; Lacerda, JF; Lacerda, JM; Lourenço, MF; Martins, C; Rodrigues, A | 1 |
| Naylor, RJ; Tuladhar, BR; Womack, MD | 1 |
| Horikoshi, K; Ishii, A; Karasawa, A; Kishibayashi, N; Ohmori, K; Yokoyama, T | 1 |
| Kulkarni, SK; Naidu, PS | 1 |
| Bauzon, D; Bymaster, FP; Cohen, ML; DeLapp, NW; Falcone, JF; Kennedy, JS; Schenck, K | 1 |
| Jumblatt, JE; Yang, X | 1 |
| Allgar, V; Goss, I; Overend, M; Pedley, I; Riley, M; Watters, J; Whitehead, A | 1 |
| Bauer, S; Brockmöller, J; Kaiser, R; Roots, I; Störmer, E; Tremblay, PB | 1 |
| Alahuhta, S; Jokela, R; Kangas-Saarela, T; Koivuranta, M; Purhonen, S | 1 |
| Bauer, S; Brockmöller, J; Kaiser, R; Papies, A; Possinger, K; Roots, I; Schelenz, C; Sezer, O; Tremblay, PB | 1 |
| Argiriadou, H; Georgiou, M; Papagiannopoulou, P; Papaziogas, B; Papaziogas, T; Parlapani, A; Pavlidis, T | 1 |
| Liu, HF; Lu, ZH; Sheng, PT; Wang, C; Wang, LY; Xiong, LZ; Xu, N; Yang, XY | 1 |
| Domröse, U; Dunker, N; Gollnick, H; Neumann, KH; Weisshaar, E | 1 |
| Banks, SL; Gurrin, LC; Orlikowski, CE; Paech, MJ; Pavy, TJ; Rucklidge, MW | 1 |
| Brockmoller, J; Kaiser, R; Possinger, K; Roots, I; Rosler, N; Schelenz, C; Sezer, O; Tremblay, PB | 1 |
| Dunker, N; Gollnick, H; Röhl, FW; Weisshaar, E | 1 |
| Endo, T; Hamaue, N; Hirafuji, M; Minami, M | 1 |
| Day, J; Haque, SM; Kellum, JM; King, B | 1 |
| Dukat, M; Wesołowska, A | 1 |
| Abali, H; Aynacioglu, AS; Babaoglu, MO; Bayar, B; Bozkurt, A; Celik, I; Kerb, R | 1 |
| Halonen, PM; Kainu, JP; Korttila, KT; Sarvela, PJ; Soikkeli, AI | 1 |
| Nylander, O; Pihl, L | 1 |
| Fletcher, PJ; Funk, D; Harding, S; Juzytsch, W; Lê, AD; Shaham, Y | 1 |
| Fujita, Y; Hagiwara, H; Hashimoto, K; Ishima, T; Iyo, M | 1 |
| Neufeld, SM; Newburn-Cook, CV | 1 |
| Arnold, D; Grothey, A; Hinke, A; Jordan, K; Schmoll, HJ; Voigt, W; Wolf, HH | 1 |
| Quan, X; Ye, TH; Zhu, B | 1 |
| Barbaud, A; Bursztejn, AC; Cuny, JF; Schmutz, JL; Tréchot, P | 1 |
| Coppé, MC; Gillardin, JM; Girard, P; Niedergang, B; Pansart, Y | 1 |
| Araki, H; Cui, R; Kohnomi, S; Li, B; Suemaru, K | 1 |
| Du Bois, A | 1 |
| Ayuhara, H; Okuyama, K; Ozeki, T; Takayanagi, R; Yamada, Y; Yokoyama, H; Yoshimoto, K | 1 |
| Araki, H; Choshi, T; Goda, M; Hibino, S; Kawasaki, H; Kohnomi, S; Suemaru, K | 1 |
| Bokelmann, K; Brockmöller, J; Kaiser, R; Meineke, I; Saadatmand, AR; Tzvetkov, MV | 1 |
| Aydın, N; Ekinci, O; Işıtmangil, G; Malat, I | 1 |
| Askitopoulou, H; Chatzimichali, A; Metaxari, M; Papaioannou, A; Petrou, A; Pharmakalidou, E | 1 |
| Iwata, N; Kishi, T; Matsuda, Y; Mukai, T | 1 |
| Huang, J; Li, L; Xu, L; You, T | 1 |
| Hori, M; Horie, S; Horiguchi, K; Iino, S; Kondo, M; Maehara, T; Matsumoto, K; Murata, T; Ozaki, H; Shimada, S; Tsubone, H | 1 |
| Du, Y; Lin, X; Liu, J; Ni, J; Tang, Y; Zeng, K; Zhou, J | 1 |
| Dehpour, AR; Haj-Mirzaian, A; Kordjazy, N; Mansouri, P; Ostadhadi, S | 1 |
| Jahn, F; Jahn, P; Jordan, K; Riesner, A; Sieker, F; Vordermark, D | 1 |
| Amini-Khoei, H; Amiri, S; Dehpour, A; Haj-Mirzaian, A; Kordjazy, N; Ostadhadi, S | 1 |
| Liu, Z; Ruan, L; Zhou, C; Zhu, Y | 1 |
| Agundez, J; Bell, GC; Caudle, KE; Gaedigk, A; Gordon, RJ; Hikino, K; Klein, TE; Prows, CA; Sadhasivam, S; Schwab, M; Whirl-Carrillo, M | 1 |
| Huang, C; Li, J; Sun, Y; Wan, H; Wang, Q; Zhang, H; Zhang, J; Zhong, H | 1 |
| Altman, RB; Huddart, R; Klein, TE | 1 |
| Barakat, GH; El-Bagary, RI; Hassib, ST; Taha, EA | 1 |
| Hayes, AW; Jafarian, AH; Karimi, G; Mehri, S; Rahimian, R; Zirak, MR | 1 |
| Chen, Y; Song, X; Wang, J; Wang, N; Wang, R | 1 |
| Alimoradi, H; Baird, SK; Barzegar-Fallah, A; Dunlop, JL; Torbati, E | 1 |
| Dehpour, AR; Eslami, F; Golroudbari, HT; Jafari, RM; Khosravi, A; Maroufi, SF; Rashidian, A; Shayan, M | 1 |
21 review(s) available for ondansetron and tropisetron
| Article | Year |
|---|---|
5-HT3 receptor antagonists, a new approach in emesis: a review of ondansetron, granisetron and tropisetron.
Topics: Animals; Antiemetics; Granisetron; Humans; Imidazoles; Indazoles; Indoles; Ondansetron; Serotonin Antagonists; Tropisetron; Vomiting | 1991 |
[Chemotherapy-induced emesis and serotonin antagonists].
Topics: Antiemetics; Antineoplastic Agents; Granisetron; Humans; Indoles; Ondansetron; Serotonin Antagonists; Tropisetron; Vomiting | 1991 |
Antiemetic control: 5-HT3 antagonists: review of clinical results, with particular emphasis on ondansetron.
Topics: Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Granisetron; Headache; Humans; Imidazoles; Indazoles; Indoles; Nausea; Ondansetron; Radiation Injuries; Radiotherapy; Serotonin Antagonists; Tropisetron; Vomiting | 1990 |
[Cholestatic pruritus--pathophysiology and therapy with special reference to treatment with 5-hydroxytryptamine subtype 3 receptor antagonists].
Topics: Adult; Child; Cholestasis, Intrahepatic; Female; Humans; Indoles; Male; Nociceptors; Ondansetron; Pregnancy; Pruritus; Receptors, Serotonin; Serotonin Antagonists; Tropisetron | 1995 |
Review of the preclinical pharmacology and comparative efficacy of 5-hydroxytryptamine-3 receptor antagonists for chemotherapy-induced emesis.
Topics: Antiemetics; Antineoplastic Agents; Cisplatin; Granisetron; Humans; Indoles; Ondansetron; Prognosis; Selective Serotonin Reuptake Inhibitors; Tropisetron; Vomiting | 1995 |
Are there differences among the serotonin antagonists?
Topics: Animals; Antiemetics; Cisplatin; Clinical Trials as Topic; Dose-Response Relationship, Drug; Granisetron; Humans; Indoles; Neoplasms; Ondansetron; Serotonin Antagonists; Tropisetron; Vomiting | 1994 |
The pharmacology of the 5-HT4 receptor.
Topics: 4-Aminobenzoic Acid; 5-Hydroxytryptophan; Animals; Anxiety; Arousal; Brain; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Indoles; Mice; Neural Inhibition; Ondansetron; para-Aminobenzoates; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Tropisetron | 1993 |
Assessing the comparative clinical value of tropisetron.
Topics: Antiemetics; Evaluation Studies as Topic; Humans; Indoles; Ondansetron; Randomized Controlled Trials as Topic; Treatment Outcome; Tropisetron; Vomiting | 1995 |
Progress in reducing nausea and emesis. Comparisons of ondansetron (Zofran), granisetron (Kytril), and tropisetron (Navoban).
Topics: Antiemetics; Antineoplastic Agents; Granisetron; Humans; Indoles; Nausea; Ondansetron; Serotonin Antagonists; Tropisetron; Vomiting | 1995 |
[Anti-5-HT-3: a new group of antiemetics].
Topics: Adult; Antiemetics; Granisetron; Humans; Indoles; Ondansetron; Serotonin Antagonists; Time Factors; Tropisetron | 1996 |
[Prevention and treatment of postoperative nausea and vomiting with 5-HT3-receptor blockers].
Topics: Antiemetics; Clinical Trials as Topic; Dose-Response Relationship, Drug; Granisetron; Humans; Indoles; Infusions, Intravenous; Nausea; Ondansetron; Postoperative Complications; Quinolizines; Serotonin Antagonists; Tropisetron; Vomiting | 1996 |
[Recent improvements in antiemetic therapy].
Topics: Antiemetics; Antineoplastic Agents; Cisplatin; Dexamethasone; Drug Therapy, Combination; Granisetron; Humans; Indoles; Metoclopramide; Nausea; Ondansetron; Phenothiazines; Serotonin Antagonists; Tropisetron; Vomiting | 1997 |
[Serotonin and anticancer drug-induced emesis].
Topics: Animals; Antiemetics; Antineoplastic Agents; Cisplatin; Enterochromaffin Cells; Granisetron; Humans; Indoles; Ondansetron; Receptors, Serotonin, 5-HT3; Receptors, Serotonin, 5-HT4; Serotonin; Serotonin 5-HT3 Receptor Antagonists; Serotonin 5-HT4 Receptor Antagonists; Serotonin Antagonists; Tropisetron; Vagus Nerve; Vomiting | 2004 |
Update on anti-emetics for chemotherapy-induced emesis.
Topics: Administration, Oral; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Australia; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Granisetron; Humans; Indoles; Isoquinolines; Male; Neoplasms; Ondansetron; Palonosetron; Patient Satisfaction; Prognosis; Quality of Life; Quinolizines; Quinuclidines; Treatment Outcome; Tropisetron; Vomiting | 2005 |
The efficacy of 5-HT3 receptor antagonists for the prevention of postoperative nausea and vomiting after craniotomy: a meta-analysis.
Topics: Antiemetics; Craniotomy; Data Interpretation, Statistical; Granisetron; Humans; Indoles; Ondansetron; Postoperative Nausea and Vomiting; Randomized Controlled Trials as Topic; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Treatment Outcome; Tropisetron | 2007 |
A meta-analysis comparing the efficacy of four 5-HT3-receptor antagonists for acute chemotherapy-induced emesis.
Topics: Antiemetics; Antineoplastic Agents; Granisetron; Humans; Indoles; Ondansetron; Quinolizines; Serotonin 5-HT3 Receptor Antagonists; Serotonin Antagonists; Treatment Outcome; Tropisetron; Vomiting | 2007 |
[Management of chemotherapy-induced emesis: what is the standard after 20 years of clinical research].
Topics: Antineoplastic Combined Chemotherapy Protocols; Benchmarking; Dexamethasone; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Granisetron; Humans; Indoles; Metoclopramide; Nausea; Ondansetron; Premedication; Randomized Controlled Trials as Topic; Research; Serotonin 5-HT3 Receptor Antagonists; Tropisetron; Vomiting | 1998 |
Selective serotonin 3 receptor antagonist treatment for schizophrenia: meta-analysis and systematic review.
Topics: Antipsychotic Agents; Constipation; Double-Blind Method; Drug Therapy, Combination; Granisetron; Haloperidol; Humans; Indoles; Nausea; Ondansetron; Randomized Controlled Trials as Topic; Receptors, Serotonin, 5-HT3; Risperidone; Schizophrenia; Serotonin 5-HT3 Receptor Antagonists; Severity of Illness Index; Symptom Assessment; Treatment Outcome; Tropisetron; Vomiting | 2014 |
5-HT3 receptor antagonists for the prevention of postoperative shivering: a meta-analysis.
Topics: Analgesics, Opioid; Granisetron; Humans; Indoles; Isoquinolines; Meperidine; Ondansetron; Palonosetron; Postoperative Complications; Postoperative Period; Quinuclidines; Randomized Controlled Trials as Topic; Receptors, Serotonin, 5-HT3; Serotonin 5-HT3 Receptor Antagonists; Shivering; Surgical Procedures, Operative; Tropisetron | 2016 |
Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline for CYP2D6 genotype and use of ondansetron and tropisetron.
Topics: Antiemetics; Cytochrome P-450 CYP2D6; Drug-Related Side Effects and Adverse Reactions; Genetic Testing; Humans; Ondansetron; Pharmacogenetics; Polymorphism, Genetic; Postoperative Nausea and Vomiting; Radiotherapy; Serotonin 5-HT3 Receptor Agonists; Tropisetron | 2017 |
Comparison of ondansetron and tropisetron in preventing postoperative nausea and vomiting: A meta-analysis of randomized controlled trials.
Topics: Antiemetics; Double-Blind Method; Humans; Ondansetron; Postoperative Nausea and Vomiting; Randomized Controlled Trials as Topic; Tropisetron; Vomiting | 2021 |
35 trial(s) available for ondansetron and tropisetron
| Article | Year |
|---|---|
Ondansetron and tropisetron with dexamethasone in the prophylaxis of acute vomiting induced by non-cisplatin-containing chemotherapy.
Topics: Acute Disease; Adult; Aged; Antineoplastic Agents; Dexamethasone; Drug Therapy, Combination; Female; Humans; Indoles; Male; Middle Aged; Ondansetron; Serotonin Antagonists; Tropisetron; Vomiting | 1992 |
Is Navoban (tropisetron) as effective as Zofran (ondansetron) in cisplatin-induced emesis? The French Navoban Study Group.
Topics: Antiemetics; Cisplatin; Double-Blind Method; Female; Humans; Indoles; Male; Middle Aged; Nausea; Neoplasms; Ondansetron; Tropisetron; Vomiting | 1995 |
Possible lack of full cross-resistance of 5HT3 antagonists; a pilot study.
Topics: Adult; Aged; Antiemetics; Cisplatin; Cross-Over Studies; Drug Resistance; Female; Humans; Indoles; Male; Middle Aged; Nausea; Ondansetron; Pilot Projects; Serotonin Antagonists; Tropisetron; Vomiting | 1995 |
5-HT3 receptor antagonists in the prophylaxis of acute vomiting induced by moderately emetogenic chemotherapy--a randomised study.
Topics: Adult; Aged; Aged, 80 and over; Antiemetics; Antineoplastic Agents; Female; Granisetron; Humans; Indoles; Male; Middle Aged; Neoplasms; Ondansetron; Patient Satisfaction; Prospective Studies; Receptors, Serotonin; Serotonin Antagonists; Tropisetron; Vomiting | 1993 |
Comparison of granisetron, ondansetron, and tropisetron in the prophylaxis of acute nausea and vomiting induced by cisplatin for the treatment of head and neck cancer: a randomized controlled trial.
Topics: Adult; Aged; Antiemetics; Antineoplastic Agents; Cisplatin; Drug Administration Schedule; Female; Granisetron; Head and Neck Neoplasms; Humans; Indoles; Male; Middle Aged; Nausea; Ondansetron; Prospective Studies; Serotonin Antagonists; Tropisetron; Vomiting | 1996 |
Prevention of delayed emesis by a single intravenous bolus dose of 5-HT3-receptor-antagonist in moderately emetogenic chemotherapy.
Topics: Adolescent; Adult; Aged; Antiemetics; Antineoplastic Agents; Breast Neoplasms; Cisplatin; Cost-Benefit Analysis; Cyclophosphamide; Epirubicin; Female; Fluorouracil; Granisetron; Granulocyte Colony-Stimulating Factor; Humans; Indoles; Injections, Intravenous; Methotrexate; Middle Aged; Ondansetron; Serotonin Antagonists; Tropisetron; Vomiting | 1996 |
Prophylactic antiemetic therapy with ondansetron, tropisetron, granisetron and metoclopramide in patients undergoing laparoscopic cholecystectomy: a randomized, double-blind comparison with placebo.
Topics: Adult; Aged; Antiemetics; Cholecystectomy, Laparoscopic; Double-Blind Method; Female; Granisetron; Humans; Indoles; Male; Metoclopramide; Middle Aged; Nausea; Ondansetron; Postoperative Complications; Prospective Studies; Serotonin Antagonists; Tropisetron; Vomiting | 1996 |
Comparison of Granisetron, ondansetron, and tropisetron in the prophylaxis of acute nausea and vomiting induced by cisplatin for the treatment of head and neck cancer. A randomized controlled trial.
Topics: Acute Disease; Antiemetics; Antineoplastic Agents; Cisplatin; Data Interpretation, Statistical; Granisetron; Humans; Indoles; Nausea; Ondansetron; Randomized Controlled Trials as Topic; Tropisetron | 1996 |
Tropisetron or ondansetron compared with placebo for prevention of postoperative nausea and vomiting.
Topics: Abdomen; Adolescent; Adult; Aged; Antiemetics; Double-Blind Method; Female; Humans; Indoles; Male; Middle Aged; Ondansetron; Placebos; Postoperative Nausea and Vomiting; Prospective Studies; Tropisetron | 1998 |
Serotonin receptor antagonists in prophylaxis of acute and delayed emesis induced by moderately emetogenic, single-day chemotherapy: a randomized study.
Topics: Adult; Aged; Antiemetics; Antineoplastic Agents; Female; Granisetron; Humans; Indoles; Male; Middle Aged; Ondansetron; Prospective Studies; Serotonin Antagonists; Tropisetron; Vomiting | 1999 |
Comparison of ondansetron and tropisetron combined with droperidol for the prevention of emesis in women with a history of post-operative nausea and vomiting.
Topics: Adult; Anesthesia, General; Antiemetics; Double-Blind Method; Droperidol; Drug Therapy, Combination; Female; Gynecologic Surgical Procedures; Humans; Indoles; Laparoscopy; Middle Aged; Ondansetron; Postoperative Nausea and Vomiting; Risk Factors; Serotonin Antagonists; Tropisetron | 1999 |
Prevention of postoperative nausea and vomiting in gynaecological laparotomies: a comparison of tropisetron and ondansetron.
Topics: Antiemetics; Double-Blind Method; Female; Gynecologic Surgical Procedures; Humans; Indoles; Laparotomy; Middle Aged; Ondansetron; Postoperative Nausea and Vomiting; Serotonin Antagonists; Tropisetron | 1999 |
Tropisetron or ondansetron for the prevention of post-operative nausea and vomiting (PONV)
Topics: Adult; Aged; Antiemetics; Double-Blind Method; Female; Humans; Indoles; Middle Aged; Ondansetron; Postoperative Nausea and Vomiting; Prospective Studies; Serotonin Antagonists; Tropisetron | 1999 |
Granisetron, tropisetron, and ondansetron in the prevention of acute emesis induced by a combination of cisplatin-Adriamycin and by high-dose ifosfamide delivered in multiple-day continuous infusions.
Topics: Acute Disease; Adolescent; Adult; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool; Cisplatin; Doxorubicin; Drug Administration Schedule; Extremities; Female; Granisetron; Humans; Ifosfamide; Indoles; Male; Ondansetron; Osteosarcoma; Tropisetron; Vomiting | 2000 |
Comparison of granisetron, ondansetron and tropisetron for control of vomiting and nausea induced by cisplatin.
Topics: Adult; Antiemetics; Antineoplastic Agents; Cisplatin; Cost-Benefit Analysis; Female; Granisetron; Humans; Indoles; Injections, Intravenous; Male; Middle Aged; Nausea; Neoplasms; Ondansetron; Treatment Outcome; Tropisetron; Vomiting, Anticipatory | 2000 |
Comparative efficacy of three 5-HT3 antagonists (granisetron, ondansetron, and tropisetron) plus dexamethasone for the prevention of cisplatin-induced acute emesis: a randomized crossover study.
Topics: Adult; Aged; Antiemetics; Antineoplastic Agents; Cisplatin; Cross-Over Studies; Dexamethasone; Female; Granisetron; Head and Neck Neoplasms; Humans; Indoles; Injections, Intravenous; Male; Middle Aged; Ondansetron; Patient Satisfaction; Treatment Outcome; Tropisetron; Vomiting | 2000 |
[Effects of oral 5-HT3 antagonists on chemotherapy-induced emesis in patients with gynecologic cancers].
Topics: Administration, Oral; Antiemetics; Benzimidazoles; Carboplatin; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Female; Genital Neoplasms, Female; Granisetron; Humans; Indoles; Middle Aged; Nausea; Ondansetron; Paclitaxel; Serotonin Antagonists; Tropisetron; Vomiting | 2000 |
Randomised double blind crossover study comparing ondansetron, granisetron and tropisetron. A cost-benefit analysis.
Topics: Adult; Aged; Antiemetics; Antineoplastic Agents; Cost-Benefit Analysis; Cross-Over Studies; Drug Costs; Female; Granisetron; Health Care Costs; Humans; Indoles; Male; Middle Aged; Nausea; Neoplasms; Ondansetron; Treatment Outcome; Tropisetron; Vomiting | 2000 |
Treatment of chronic fatigue syndrome with 5-HT3 receptor antagonists--preliminary results.
Topics: Adolescent; Adult; Fatigue Syndrome, Chronic; Female; Humans; Indoles; Male; Middle Aged; Ondansetron; Patient Selection; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Tropisetron | 2000 |
Antiemetic efficacy of three serotonin antagonists during high-dose chemotherapy and autologous stem cell transplantation in malignant lymphoma.
Topics: Adult; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Combined Modality Therapy; Cytarabine; Etoposide; Female; Granisetron; Hematopoietic Stem Cell Transplantation; Humans; Indoles; Lymphoma; Male; Melphalan; Nausea; Ondansetron; Serotonin Antagonists; Transplantation, Autologous; Tropisetron; Vomiting | 2000 |
Randomized trial of ondansetron, granisetron, and tropisetron in the prevention of acute nausea and vomiting.
Topics: Adult; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Female; Granisetron; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppression Therapy; Indoles; Leukemia; Male; Multiple Myeloma; Myelodysplastic Syndromes; Nausea; Ondansetron; Transplantation, Autologous; Transplantation, Homologous; Tropisetron; Vomiting | 2000 |
The development of a protocol for the use of 5-HT3 antagonists in chemotherapy-induced nausea and vomiting.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Clinical Protocols; Female; Granisetron; Humans; Indoles; Male; Middle Aged; Nausea; Neoplasms; Ondansetron; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Treatment Outcome; Tropisetron; Vomiting | 2001 |
Oral ondansetron, tropisetron or metoclopramide to prevent postoperative nausea and vomiting: a comparison in high-risk patients undergoing thyroid or parathyroid surgery.
Topics: Adult; Analgesics, Opioid; Antiemetics; Double-Blind Method; Female; Humans; Indoles; Male; Metoclopramide; Ondansetron; Oxycodone; Pain, Postoperative; Parathyroid Glands; Postoperative Nausea and Vomiting; Prospective Studies; Risk; Thyroid Gland; Tropisetron | 2002 |
Patient-tailored antiemetic treatment with 5-hydroxytryptamine type 3 receptor antagonists according to cytochrome P-450 2D6 genotypes.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Cytochrome P-450 CYP2D6; Female; Gene Expression Profiling; Genetic Predisposition to Disease; Genotype; Humans; Indoles; Male; Middle Aged; Nausea; Neoplasms; Ondansetron; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Predictive Value of Tests; Prospective Studies; Risk Factors; Serotonin Antagonists; Tropisetron; Vomiting | 2002 |
Tropisetron vs ondansetron for prevention of postoperative nausea and vomiting after laparoscopic cholecystectomy: a randomized double-blind, placebo-controlled study.
Topics: Adult; Antiemetics; Cholecystectomy, Laparoscopic; Double-Blind Method; Female; Headache; Humans; Indoles; Infusions, Intravenous; Male; Middle Aged; Ondansetron; Postoperative Nausea and Vomiting; Sleep Wake Disorders; Tropisetron | 2002 |
[Dexamethasone enhances the effect of tropisetron and ondansetron against nausea and vomiting against nausea and vomiting after patient-controlled analgesia].
Topics: Analgesia, Patient-Controlled; Anti-Inflammatory Agents; Antiemetics; Dexamethasone; Drug Synergism; Drug Therapy, Combination; Humans; Indoles; Nausea; Ondansetron; Treatment Outcome; Tropisetron; Vomiting; Wound Healing | 2002 |
Plasma serotonin and histamine levels in hemodialysis-related pruritus are not significantly influenced by 5-HT3 receptor blocker and antihistaminic therapy.
Topics: Adult; Cetirizine; Female; Histamine; Histamine H1 Antagonists, Non-Sedating; Humans; Indoles; Male; Middle Aged; Ondansetron; Pruritus; Renal Dialysis; Renal Insufficiency; Serotonin; Serotonin Antagonists; Treatment Outcome; Tropisetron | 2003 |
The efficacy and cost-effectiveness of prophylactic 5-hydroxytryptamine3 receptor antagonists: tropisetron, ondansetron and dolasetron.
Topics: Antiemetics; Cost-Benefit Analysis; Double-Blind Method; Female; Humans; Indoles; Middle Aged; Ondansetron; Patient Satisfaction; Postoperative Nausea and Vomiting; Quinolizines; Serotonin Antagonists; Tropisetron | 2003 |
Antipruritic effects of two different 5-HT3 receptor antagonists and an antihistamine in haemodialysis patients.
Topics: Adult; Aged; Antipruritics; Cetirizine; Female; Histamine; Histamine H1 Antagonists; Humans; Indoles; Iontophoresis; Male; Middle Aged; Ondansetron; Pruritus; Reflex; Renal Dialysis; Renal Insufficiency; Serotonin; Serotonin 5-HT3 Receptor Antagonists; Serotonin Antagonists; Skin; Skin Temperature; Treatment Outcome; Tropisetron | 2004 |
Association of the ABCB1 3435C>T polymorphism with antiemetic efficacy of 5-hydroxytryptamine type 3 antagonists.
Topics: Adult; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; ATP-Binding Cassette Transporters; Female; Gene Frequency; Genotype; Granisetron; Humans; Indoles; Male; Middle Aged; Nausea; Neoplasms; Ondansetron; Polymorphism, Single Nucleotide; Prospective Studies; Serotonin 5-HT3 Receptor Antagonists; Serotonin Antagonists; Time Factors; Treatment Outcome; Tropisetron; Vomiting | 2005 |
Ondansetron and tropisetron do not prevent intraspinal morphine- and fentanyl-induced pruritus in elective cesarean delivery.
Topics: Adult; Analgesics, Opioid; Anesthesia, Epidural; Anesthesia, Spinal; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Cesarean Section; Double-Blind Method; Elective Surgical Procedures; Female; Fentanyl; Humans; Indoles; Injections, Spinal; Ketoprofen; Morphine; Ondansetron; Pain, Postoperative; Postoperative Nausea and Vomiting; Pregnancy; Prospective Studies; Pruritus; Time Factors; Treatment Outcome; Tropisetron | 2006 |
[A randomized double-blind study of prevention of postoperative nausea and vomiting with ondansetron, tropisetron, or granisetron in patients undergoing general anesthesia].
Topics: Adolescent; Adult; Aged; Anesthesia, General; Antiemetics; Double-Blind Method; Female; Granisetron; Humans; Indoles; Male; Middle Aged; Ondansetron; Postoperative Nausea and Vomiting; Tropisetron; Young Adult | 2007 |
A randomized comparison of droperidol, metoclopramide, tropisetron, and ondansetron for the prevention of postoperative nausea and vomiting.
Topics: Adult; Anesthesia Recovery Period; Antiemetics; Conscious Sedation; Droperidol; Female; Gynecologic Surgical Procedures; Humans; Indoles; Metoclopramide; Middle Aged; Ondansetron; Postoperative Nausea and Vomiting; Tropisetron | 2011 |
Antiemetic prophylaxis in thyroid surgery: a randomized, double-blind comparison of three 5-HT3 agents.
Topics: Adult; Aged; Antiemetics; Double-Blind Method; Female; Granisetron; Humans; Indoles; Male; Middle Aged; Ondansetron; Postoperative Nausea and Vomiting; Preanesthetic Medication; Serotonin 5-HT3 Receptor Antagonists; Thyroidectomy; Tropisetron; Young Adult | 2011 |
Addition of the Neurokinin-1-Receptor Antagonist (RA) Aprepitant to a 5-Hydroxytryptamine-RA and Dexamethasone in the Prophylaxis of Nausea and Vomiting Due to Radiation Therapy With Concomitant Cisplatin.
Topics: Antiemetics; Antineoplastic Agents; Aprepitant; Chemoradiotherapy; Cisplatin; Dexamethasone; Drug Therapy, Combination; Esophageal Neoplasms; Female; Head and Neck Neoplasms; Humans; Indoles; Lung Neoplasms; Male; Middle Aged; Morpholines; Nausea; Neurokinin-1 Receptor Antagonists; Ondansetron; Prospective Studies; Serotonin Antagonists; Tropisetron; Uterine Cervical Neoplasms; Vomiting | 2015 |
101 other study(ies) available for ondansetron and tropisetron
| Article | Year |
|---|---|
Novel 5-HT3 antagonists: indol-3-ylspiro(azabicycloalkane-3,5'(4'H)-oxazoles).
Topics: Animals; Binding Sites; Brain; Bridged Bicyclo Compounds; Indoles; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Oxazoles; Rats; Serotonin Antagonists; Stereoisomerism; Structure-Activity Relationship; X-Ray Diffraction | 1992 |
Zatosetron, a potent, selective, and long-acting 5HT3 receptor antagonist: synthesis and structure-activity relationships.
Topics: Animals; Benzofurans; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Guinea Pigs; Heart Rate; In Vitro Techniques; Indoles; Male; Muscle Contraction; Muscle, Smooth; Rats; Rats, Inbred Strains; Serotonin Antagonists; Structure-Activity Relationship; Tropisetron | 1992 |
An initial three-component pharmacophore for specific serotonin-3 receptor ligands.
Topics: Animals; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Computer Graphics; Computer Simulation; Imidazoles; In Vitro Techniques; Indoles; Ligands; Mice; Models, Molecular; Ondansetron; Rats; Receptors, Serotonin; Serotonin Antagonists; Structure-Activity Relationship; Thiazoles; Tropisetron | 1990 |
Thiazole as a carbonyl bioisostere. A novel class of highly potent and selective 5-HT3 receptor antagonists.
Topics: Administration, Oral; Animals; Computer Graphics; In Vitro Techniques; Mice; Models, Molecular; Neurons; Radioligand Assay; Rats; Receptors, Serotonin; Serotonin Antagonists; Structure-Activity Relationship; Thiazoles; Tumor Cells, Cultured | 1990 |
Synthesis, in vitro binding profile, and central nervous system penetrability of the highly potent 5-HT3 receptor antagonist [3H]-4-(2-methoxyphenyl)-2-[4(5)-methyl-5(4)-imidazolylmethyl]thiazole.
Topics: Animals; Blood-Brain Barrier; Brain; Chemical Phenomena; Chemistry; Glioma; Imidazoles; Mice; Molecular Structure; Neuroblastoma; Serotonin Antagonists; Thiazoles; Tumor Cells, Cultured | 1990 |
Synthesis and biochemical evaluation of tritium-labeled 1-methyl-N-(8-methyl-8-azabicyclo[3.2.1]oct-3-yl)-1H-indazole-3-carboxa mide, a useful radioligand for 5HT3 receptors.
Topics: Animals; Cell Membrane; Cerebral Cortex; Guinea Pigs; Heart Rate; Ileum; Indazoles; Male; Methylation; Myocardium; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Structure-Activity Relationship; Tritium; Tropanes | 1990 |
Aromatic thiazole derivatives: structurally novel and selective serotonin-3 receptor antagonists.
Topics: Animals; Binding, Competitive; Heart Rate; Molecular Structure; Rats; Receptors, Serotonin; Serotonin Antagonists; Structure-Activity Relationship; Thiazoles; Tumor Cells, Cultured | 1990 |
Conformation-activity relationship study of 5-HT3 receptor antagonists and a definition of a model for this receptor site.
Topics: Animals; Binding Sites; Guinea Pigs; Mice; Protein Conformation; Rabbits; Rats; Receptors, Serotonin; Serotonin Antagonists; Structure-Activity Relationship | 1990 |
2-(Quinuclidin-3-yl)pyrido[4,3-b]indol-1-ones and isoquinolin-1-ones. Potent conformationally restricted 5-HT3 receptor antagonists.
Topics: Animals; Cisplatin; Computer Simulation; Dogs; Ferrets; Isoquinolines; Male; Models, Molecular; Molecular Structure; Palonosetron; Pyridones; Quinuclidines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Antagonists; Stereoisomerism; Structure-Activity Relationship; Vomiting | 1993 |
Phenylimidazolidin-2-one derivatives as selective 5-HT3 receptor antagonists and refinement of the pharmacophore model for 5-HT3 receptor binding.
Topics: Animals; Binding, Competitive; Brain; Guinea Pigs; Heart Rate; Ileum; Imidazoles; Models, Molecular; Molecular Structure; Muscles; Rats; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Antagonists | 1997 |
5-HT3 antagonists derived from aminopyridazine-type muscarinic M1 agonists.
Topics: Animals; Brain Stem; Hippocampus; In Vitro Techniques; Models, Molecular; Muscarinic Agonists; Myocardium; Protein Conformation; Pyridazines; Rats; Receptors, Muscarinic; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Antagonists | 1998 |
The 5-HT3 antagonist tropisetron (ICS 205-930) is a potent and selective alpha7 nicotinic receptor partial agonist.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Cell Membrane; Hippocampus; Indoles; Inhibitory Concentration 50; Intestine, Small; Ligands; Membrane Potentials; Mice; Nicotinic Agonists; Oocytes; Protein Binding; Rats; Receptors, Nicotinic; Serotonin Antagonists; Structure-Activity Relationship; Tropisetron; Xenopus | 2001 |
Activity of alpha7-selective agonists at nicotinic and serotonin 5HT3 receptors expressed in Xenopus oocytes.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Bridged-Ring Compounds; Dose-Response Relationship, Drug; Female; Indoles; Nicotinic Agonists; Ondansetron; Oocytes; Receptors, Nicotinic; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Spiro Compounds; Structure-Activity Relationship; Tropisetron; Xenopus laevis | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility | 2010 |
The influence of neuronal 5-hydroxytryptamine receptor antagonists on non-cholinergic ganglionic transmission in the guinea-pig enteric excitatory reflex.
Topics: Animals; Benzamides; Benzimidazoles; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Female; Guinea Pigs; Indoles; Intestine, Small; Male; Methiothepin; Muscle Contraction; Ondansetron; Serotonin Antagonists; Synaptic Transmission; Tropisetron | 1992 |
5-hydroxytryptamine is a fast excitatory transmitter at 5-HT3 receptors in rat amygdala.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Amygdala; Animals; Electric Stimulation; gamma-Aminobutyric Acid; Imidazoles; Indoles; Membrane Potentials; Ondansetron; Quinoxalines; Rats; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Synapses; Tropisetron | 1992 |
Involvement of 5-HT1, 5-HT2, and 5-HT3 receptors in the mediation of the prolactin response to serotonin and 5-hydroxytryptophan.
Topics: 5-Hydroxytryptophan; Animals; Dose-Response Relationship, Drug; Ergolines; Fluoxetine; Imidazoles; Indoles; Ketanserin; Male; Methysergide; Ondansetron; Prolactin; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Tropisetron | 1992 |
Central action of 5-HT3 receptor ligands in the regulation of sleep-wakefulness and raphe neuronal activity in the rat.
Topics: Animals; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Electrophysiology; Indoles; Male; Neurons; Ondansetron; Propranolol; Pyrimidines; Raphe Nuclei; Rats; Rats, Wistar; Receptors, Serotonin; Reference Values; Serotonin; Serotonin Antagonists; Sleep; Time Factors; Tropanes; Tropisetron; Wakefulness | 1992 |
Effect of serotonin 5-HT1, 5-HT2, and 5-HT3 receptor antagonists on the prolactin response to restraint and ether stress.
Topics: Animals; Ergolines; Ether; Indoles; Ketanserin; Male; Methysergide; Ondansetron; Prolactin; Rats; Rats, Wistar; Restraint, Physical; Serotonin Antagonists; Stress, Physiological; Tropisetron | 1992 |
5-HT3 receptor antagonists reverse helpless behaviour in rats.
Topics: Analysis of Variance; Animals; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Depression; Disease Models, Animal; Helplessness, Learned; Imidazoles; Indoles; Male; Ondansetron; Rats; Rats, Inbred Strains; Serotonin Antagonists; Tropisetron | 1992 |
5-Hydroxytryptamine3 receptors sited on cholinergic axon terminals of human cerebral cortex mediate inhibition of acetylcholine release.
Topics: Acetylcholine; Aged; Axons; Calcium; Cerebral Cortex; Choline; Cholinergic Fibers; Dose-Response Relationship, Drug; Female; Humans; Imidazoles; Indoles; Male; Middle Aged; Ondansetron; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Tritium; Tropisetron | 1992 |
The effect of 5-HT3 receptor antagonists on the discriminative stimulus effects of amphetamine.
Topics: Amphetamine; Animals; Discrimination Learning; Imidazoles; Indoles; Male; Ondansetron; Quinolizines; Rats; Rats, Inbred Strains; Serotonin Antagonists; Tropanes; Tropisetron | 1992 |
Preliminary evidence for the involvement of the putative 5-HT4 receptor in zacopride- and copper sulphate-induced vomiting in the ferret.
Topics: Analysis of Variance; Animals; Antiemetics; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Copper; Copper Sulfate; Female; Ferrets; Granisetron; Imidazoles; Indazoles; Indoles; Loperamide; Male; Ondansetron; Receptors, Serotonin; Serotonin Antagonists; Tropisetron; Vomiting | 1991 |
Evidence that the amygdala is involved in the disinhibitory effects of 5-HT3 receptor antagonists.
Topics: Amygdala; Animals; Anxiety; Conflict, Psychological; Granisetron; Imidazoles; Indazoles; Indoles; Lighting; Male; Ondansetron; Raphe Nuclei; Rats; Serotonin; Serotonin Antagonists; Social Behavior; Tropanes; Tropisetron | 1991 |
Identification of putative 5-HT4 receptors in guinea-pig ascending colon.
Topics: Animals; Colon; Female; Guinea Pigs; Imidazoles; In Vitro Techniques; Indoles; Methysergide; Metoclopramide; Muscle Contraction; Ondansetron; Receptors, Serotonin; Serotonin Antagonists; Tetrodotoxin; Tropisetron | 1991 |
Effects of 5-hydroxytryptamine 3 receptor antagonists on gastrointestinal motor activity in conscious dogs.
Topics: Animals; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Digestion; Dogs; Dose-Response Relationship, Drug; Female; Gastrointestinal Motility; Granisetron; Imidazoles; Indazoles; Indoles; Infusions, Intravenous; Injections, Intravenous; Male; Motilin; Motor Activity; Muscle Contraction; Muscle, Smooth; Ondansetron; Serotonin Antagonists; Time Factors; Tropisetron | 1991 |
Serotonin antagonists: a new class of antiemetic agents.
Topics: Antiemetics; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Granisetron; Humans; Imidazoles; Indazoles; Indoles; Metoclopramide; Ondansetron; Quinolizines; Receptors, Serotonin; Serotonin Antagonists; Tropanes; Tropisetron; Vomiting | 1991 |
5-Hydroxytryptamine3 receptors mediate tachycardia in conscious instrumented dogs.
Topics: Animals; Benzamides; Blood Pressure; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Dogs; Ergolines; Heart Rate; Hexamethonium; Hexamethonium Compounds; Imidazoles; Indoles; Male; Ondansetron; Receptors, Serotonin; Serotonin; Tropisetron | 1990 |
Effects of 5-HT3 receptor antagonists on 5-HT and nicotinic depolarizations in guinea-pig submucosal neurones.
Topics: Acetylcholine; Animals; Cocaine; Curare; Electric Stimulation; Ganglionic Stimulants; Gastric Mucosa; Guinea Pigs; Hexamethonium Compounds; Imidazoles; In Vitro Techniques; Indoles; Iontophoresis; Neuromuscular Depolarizing Agents; Ondansetron; Receptors, Nicotinic; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Tropanes; Tropisetron | 1990 |
The effects of granisetron, ICS 205-930 and ondansetron on the visceral pain reflex induced by duodenal distension.
Topics: Animals; Blood Pressure; Duodenum; Granisetron; Imidazoles; Indazoles; Indoles; Male; Morphine; Muscle Contraction; Muscle, Smooth; Ondansetron; Pain; Pyrazoles; Rats; Rats, Inbred Strains; Reflex; Serotonin Antagonists; Stomach; Tropisetron; Vagotomy | 1990 |
Comparison of the 5-HT3 receptor antagonist properties of ICS 205-930, GR38032F and zacopride.
Topics: Animals; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Carbachol; Cisplatin; Guinea Pigs; Heart Rate; Imidazoles; In Vitro Techniques; Indoles; Male; Ondansetron; Receptors, Serotonin; Serotonin Antagonists; Tropisetron; Vomiting | 1989 |
Neuroanatomical sites of action of 5-HT3 receptor agonist and antagonists for alteration of aversive behaviour in the mouse.
Topics: Animals; Brain; Diazepam; Exploratory Behavior; Imidazoles; Indoles; Male; Mice; Ondansetron; Receptors, Serotonin; Serotonin Antagonists; Tropisetron | 1989 |
Differential analgesic actions of serotonin 5-HT3 receptor antagonists in the mouse.
Topics: Analgesics; Animals; Imidazoles; Indoles; Injections, Intraventricular; Male; Mice; Mice, Inbred C3H; Naloxone; Nociceptors; Ondansetron; Pain Measurement; Reaction Time; Serotonin Antagonists; Tropanes; Tropisetron | 1989 |
Effects of cisapride on cholinergic neurotransmission and propulsive motility in the guinea pig ileum.
Topics: Acetylcholine; Animals; Cisapride; Gastrointestinal Motility; Guinea Pigs; Ileum; Imidazoles; In Vitro Techniques; Indoles; Membrane Potentials; Ondansetron; Peristalsis; Piperidines; Serotonin; Serotonin Antagonists; Synapses; Synaptic Transmission; Tropisetron | 1989 |
[Effect of 5-HT3 receptor antagonists on gastrointestinal motility].
Topics: Animals; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Dogs; Gastrointestinal Motility; Granisetron; Imidazoles; In Vitro Techniques; Indazoles; Indoles; Motilin; Ondansetron; Rabbits; Serotonin Antagonists; Tropisetron | 1989 |
5-HT3 receptor antagonists: a new class of antiemetics.
Topics: Antiemetics; Humans; Imidazoles; Indoles; Ondansetron; Receptors, Serotonin; Serotonin Antagonists; Tropisetron; Vomiting | 1987 |
Molecular surface comparison. 2. Similarity of electrostatic vector fields in drug design.
Topics: Anti-Anxiety Agents; Benzamides; Benzazepines; Bridged Bicyclo Compounds, Heterocyclic; Carbolines; Diazepam; Drug Design; Electricity; GABA-A Receptor Agonists; Granisetron; Indoles; Isomerism; Molecular Conformation; Ondansetron; Pharmaceutical Preparations; Protein Binding; Pyrazoles; Pyridazines; Receptors, Drug; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Structure-Activity Relationship; Surface Properties; Triazolam; Tropisetron | 1995 |
5HT3 receptor antagonists do not block nicotine induced hyperactivity in rats.
Topics: Animals; Behavior, Animal; Dose-Response Relationship, Drug; Granisetron; Haloperidol; Indoles; Male; Motor Activity; Nicotine; Ondansetron; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Time Factors; Tropanes; Tropisetron | 1995 |
Treatment of diarrhea in carcinoid syndrome with ondansetron, tropisetron, and clonidine.
Topics: Antiemetics; Clonidine; Diarrhea; Humans; Indoles; Male; Malignant Carcinoid Syndrome; Middle Aged; Ondansetron; Tropisetron | 1995 |
Serotonin3 antagonists block aversion to saccharin in an amino acid-imbalanced diet.
Topics: Amino Acids; Animals; Avoidance Learning; Conditioning, Psychological; Diet; Eating; Food Preferences; Indoles; Male; Ondansetron; Rats; Rats, Sprague-Dawley; Saccharin; Serotonin Antagonists; Tropanes; Tropisetron | 1995 |
Characterisation of the cytochrome P450 enzymes involved in the in vitro metabolism of granisetron.
Topics: Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Granisetron; Humans; Hydroxylation; In Vitro Techniques; Indoles; Isoenzymes; Kinetics; Microsomes, Liver; Ondansetron; Serotonin Antagonists; Tropisetron | 1994 |
Serotonergic innervation of the hippocampus and nucleus accumbens septi and the anxiolytic-like action of the 5-HT3 receptor antagonists.
Topics: 5,7-Dihydroxytryptamine; Animals; Anti-Anxiety Agents; Conflict, Psychological; Drinking Behavior; Electroshock; Hippocampus; Indoles; Male; Microinjections; Nucleus Accumbens; Ondansetron; Rats; Rats, Wistar; Serotonin; Serotonin Antagonists; Tropisetron | 1993 |
Role of 5-HT3 receptors in peristaltic reflex elicited by stroking the mucosa in the canine jejunum.
Topics: Animals; Atropine; Dogs; Female; Hexamethonium; Hexamethonium Compounds; Indoles; Intestinal Mucosa; Jejunum; Male; Neural Pathways; Nifedipine; Ondansetron; Peristalsis; Physical Stimulation; Receptors, Serotonin; Reflex; Serotonin Antagonists; Tetrodotoxin; Tropisetron | 1993 |
Anorectic response to amino acid imbalance: a selective serotonin3 effect?
Topics: Amino Acids; Animals; Diet; Eating; Food Preferences; Indoles; Isoleucine; Male; Ondansetron; Rats; Receptors, Serotonin; Serotonin Antagonists; Tropanes; Tropisetron | 1994 |
Inhibition of 5-hydroxytryptamine- and enterotoxin-induced fluid secretion by 5-HT receptor antagonists in the rat jejunum.
Topics: Animals; Bacterial Toxins; Body Fluids; Cholera Toxin; Enterotoxins; Escherichia coli; Escherichia coli Proteins; Female; Granisetron; Indoles; Jejunum; Ketanserin; Ondansetron; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Tropisetron | 1993 |
5-HT3 antagonists reduce morphine self-administration in rats.
Topics: Animals; Cyproheptadine; Indoles; Male; Morphine; Morphine Dependence; Ondansetron; Rats; Rats, Sprague-Dawley; Self Administration; Serotonin Antagonists; Sucrose; Tropisetron | 1993 |
The antagonist properties of S 11978 on 5HT3 receptors in N1E-115 neuroblastoma cells.
Topics: Animals; Binding, Competitive; Electrophysiology; Indoles; Kinetics; Mice; Neuroblastoma; Ondansetron; Quipazine; Serotonin Antagonists; Thiophenes; Tritium; Tropisetron; Tumor Cells, Cultured | 1993 |
5-HT3 receptor antagonists inhibit morphine-induced stimulation of mesolimbic dopamine release and function in the rat.
Topics: Animals; Behavior, Animal; Dialysis; Dopamine; Dose-Response Relationship, Drug; Granisetron; Indazoles; Indoles; Limbic System; Male; Morphine; Ondansetron; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Tropisetron | 1993 |
'... setron': are 5-HT3 receptor antagonists different?
Topics: Antiemetics; Antineoplastic Agents; Female; Granisetron; Humans; Indoles; Male; Ondansetron; Receptors, Serotonin; Serotonin Antagonists; Tropisetron; Vomiting | 1993 |
BRL 46470 potently antagonizes neural responses activated by 5-HT3 receptors.
Topics: Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Electrophysiology; Glioma; Granisetron; In Vitro Techniques; Indoles; Kinetics; Male; Neuroblastoma; Neurons; Ondansetron; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Tropisetron; Tubocurarine; Tumor Cells, Cultured; Vagus Nerve | 1993 |
Inhibition by 5-HT3 receptor antagonists of release of cholecystokinin-like immunoreactivity from the frontal cortex of freely moving rats.
Topics: Animals; Cholecystokinin; Frontal Lobe; Indoles; Male; Ondansetron; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Tropisetron; Veratrine | 1993 |
5-HT3 receptor-independent inhibition of the depolarization-induced 86Rb efflux from human neuroblastoma cells, TE671, by ondansetron.
Topics: Anti-Anxiety Agents; Benzamides; Benzofurans; Biguanides; Bridged Bicyclo Compounds, Heterocyclic; Humans; Hypoglycemic Agents; Indazoles; Indoles; Neuroblastoma; Neurotoxins; Ondansetron; Potassium Channels; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Rubidium Radioisotopes; Serotonin Antagonists; Serotonin Receptor Agonists; Structure-Activity Relationship; Tropanes; Tropisetron; Tumor Cells, Cultured | 1995 |
Hypersensitivity reactions associated with 5- hydroxytryptamine(3)-receptor antagonists: a class effect?
Topics: Aged; Antiemetics; Drug Hypersensitivity; Female; Granisetron; Humans; Indoles; Middle Aged; Ondansetron; Serotonin Antagonists; Tropisetron | 1996 |
Retention behaviour of anti-emetic serotonin antagonists in reversed phase high performance liquid chromatography.
Topics: Antiemetics; Chromatography, High Pressure Liquid; Granisetron; Indoles; Ondansetron; Serotonin Antagonists; Tropisetron | 1995 |
Characterization of the cytochrome P450 enzymes involved in the in vitro metabolism of dolasetron. Comparison with other indole-containing 5-HT3 antagonists.
Topics: Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Humans; Hydroxylation; Indoles; Male; Mass Spectrometry; Microsomes, Liver; Mixed Function Oxygenases; Molecular Structure; Ondansetron; Oxidation-Reduction; Quinolizines; Serotonin Antagonists; Tropisetron | 1996 |
The role of 5HT3 in nociceptive processing in the rat spinal cord: results from behavioural and electrophysiological studies.
Topics: Animals; Biguanides; Indoles; Male; Microinjections; Ondansetron; Pain Measurement; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spinal Cord; Time Factors; Tropisetron | 1996 |
Systemic injection of p-chloroamphetamine eliminates the effect of the 5-HT3 compounds on learning.
Topics: Animals; Association Learning; Behavior, Animal; Biguanides; Conditioning, Operant; Indoles; Learning; Male; Ondansetron; p-Chloroamphetamine; Rats; Rats, Wistar; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists; Tropisetron | 1996 |
5-HT3 receptor antagonists do not modify cocaine place conditioning or the rise in extracellular dopamine in the nucleus accumbens of rats.
Topics: Animals; Cocaine; Conditioning, Operant; Dopamine; Dopamine Uptake Inhibitors; Extracellular Space; Indoles; Male; Microdialysis; Nucleus Accumbens; Ondansetron; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Tropanes; Tropisetron | 1996 |
Which type of 5-hydroxytryptamine receptor mediates relaxation of the longitudinal muscle of guinea pig proximal colon in vitro?
Topics: Animals; Colon; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Indoles; Ketanserin; Male; Metergoline; Methiothepin; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Ondansetron; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tetrodotoxin; Tropisetron | 1996 |
The activity of dihydropyrimidine dehydrogenase from rat liver was not affected by any of five 5-hydroxytryptamine antagonists.
Topics: Animals; Antiemetics; Antimetabolites, Antineoplastic; Biotransformation; Bridged Bicyclo Compounds, Heterocyclic; Cytosol; Dihydrouracil Dehydrogenase (NADP); Fluorouracil; Granisetron; Indoles; Liver; Male; Ondansetron; Oxazines; Oxidoreductases; Quinolizines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Tropisetron | 1996 |
Effect of 5-HT2 and 5-HT3 receptor antagonists on cholera toxin-induced fluid hypersecretion in the pig jejunum.
Topics: Analysis of Variance; Animals; Cholera Toxin; Dose-Response Relationship, Drug; Granisetron; Indoles; Jejunal Diseases; Jejunum; Ketanserin; Ondansetron; Serotonin Antagonists; Swine; Swine Diseases; Tropisetron | 1996 |
Response heterogeneity of 5-HT3 receptor antagonists in a rat visceral hypersensitivity model.
Topics: Animals; Benzamides; Bridged Bicyclo Compounds, Heterocyclic; Colon; Granisetron; Indoles; Male; Muscle Contraction; Muscle, Smooth; Ondansetron; Pain; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Tropisetron | 1996 |
Always more "setrons": how many do we need?
Topics: Antiemetics; Antineoplastic Agents; Drug Costs; Granisetron; Humans; Indoles; Nausea; Ondansetron; Serotonin Antagonists; Tropisetron; Vomiting | 1997 |
Different effects of tropisetron and ondansetron in learning and memory paradigms.
Topics: Animals; Avoidance Learning; Indoles; Learning; Male; Maze Learning; Memory; Muscarinic Antagonists; Ondansetron; Rats; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Scopolamine; Serotonin Antagonists; Tropisetron | 1997 |
Effect of ondansetron and ICS 205-930 on radiation-induced hypothermia in rats.
Topics: Animals; Body Temperature; Dose-Response Relationship, Drug; Indoles; Male; Ondansetron; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Antagonists; Tropisetron | 1997 |
Ondansetron facilitates neuromuscular transmission in the guinea-pig ileum.
Topics: 5-Methoxytryptamine; Animals; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniques; Indoles; Male; Muscle Contraction; Muscle, Smooth; Ondansetron; Piperidines; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin Antagonists; Synaptic Transmission; Tropanes; Tropisetron | 1997 |
Is nitric oxide involved in 5-HT3 receptor-mediated neurogenic relaxation of guinea pig proximal colon?
Topics: Animals; Colon; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guinea Pigs; Hemoglobins; In Vitro Techniques; Indoles; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitroarginine; Ondansetron; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Tropisetron | 1998 |
Bidirectional allosteric modulation of strychnine-sensitive glycine receptors by tropeines and 5-HT3 serotonin receptor ligands.
Topics: Allosteric Regulation; Animals; Benzofurans; Binding, Competitive; Bridged Bicyclo Compounds, Heterocyclic; Glycine; Granisetron; Indoles; Ligands; Male; Medulla Oblongata; Ondansetron; Pons; Rats; Rats, Wistar; Receptors, Glycine; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Serotonin Receptor Agonists; Spinal Cord; Strychnine; Tropanes; Tropisetron; Tubocurarine | 1998 |
Radiation-induced emesis: a prospective observational multicenter Italian trial. The Italian Group for Antiemetic Research in Radiotherapy.
Topics: Adult; Antiemetics; Domperidone; Drug Administration Schedule; Female; Humans; Incidence; Indoles; Male; Metoclopramide; Middle Aged; Nausea; Ondansetron; Prognosis; Prospective Studies; Radiotherapy; Sex Factors; Time Factors; Tropisetron; Vomiting | 1999 |
Multifocal fixed drug eruption to paracetamol, tropisetron and ondansetron induced by interleukin 2.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Antiemetics; Drug Eruptions; Drug Interactions; Humans; Indoles; Interleukin-2; Melanoma; Ondansetron; Skin; Tropisetron | 2000 |
Pharmacological characterization of the 5-HT receptor-mediated contraction in the mouse isolated ileum.
Topics: Animals; Atropine; Dioxanes; Dose-Response Relationship, Drug; Female; Granisetron; Ileum; In Vitro Techniques; Indoles; Ketanserin; Male; Mice; Muscle Contraction; Ondansetron; Piperidines; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tetrodotoxin; Tropanes; Tropisetron | 2000 |
Possible involvement of 5-HT4 receptors, in addition to 5-HT3 receptors, in the emesis induced by high-dose cisplatin in Suncus murinus.
Topics: Animals; Antiemetics; Antineoplastic Agents; Cisplatin; Granisetron; Indoles; Male; Ondansetron; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Receptors, Serotonin, 5-HT4; Serotonin Antagonists; Shrews; Sulfonamides; Tropisetron; Vomiting | 2001 |
Reversal of neuroleptic-induced orofacial dyskinesia by 5-HT3 receptor antagonists.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Haloperidol; Indoles; Male; Ondansetron; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Tropisetron | 2001 |
Potent antagonism of 5-HT(3) and 5-HT(6) receptors by olanzapine.
Topics: Animals; Benzodiazepines; Binding, Competitive; Clozapine; Dibenzothiazepines; Dose-Response Relationship, Drug; Guanosine 5'-O-(3-Thiotriphosphate); Guinea Pigs; Haloperidol; HeLa Cells; Humans; Ileum; In Vitro Techniques; Indoles; Lysergic Acid; Muscle Contraction; Olanzapine; Ondansetron; Pirenzepine; Quetiapine Fumarate; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Risperidone; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sulfur Radioisotopes; Tritium; Tropisetron | 2001 |
[Presynaptic 5-hydroxytryptamine receptors enhance cholinergic neurosecretion in the human iris-ciliary body].
Topics: 5-Methoxytryptamine; Acetylcholine; Adolescent; Adult; Aged; Aged, 80 and over; Ciliary Body; Dose-Response Relationship, Drug; Female; Humans; In Vitro Techniques; Indoles; Iris; Male; Middle Aged; Ondansetron; Receptors, Presynaptic; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tritium; Tropisetron | 2001 |
Simultaneous determination of ondansetron and tropisetron in human plasma using HPLC with UV detection.
Topics: Chromatography, High Pressure Liquid; Humans; Indoles; Ondansetron; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Serotonin Antagonists; Spectrophotometry, Ultraviolet; Tropisetron | 2002 |
Variations in the 5-hydroxytryptamine type 3B receptor gene as predictors of the efficacy of antiemetic treatment in cancer patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antiemetics; Antineoplastic Agents; Female; Gene Deletion; Germany; Humans; Indoles; Logistic Models; Male; Middle Aged; Neoplasms; Ondansetron; Polymorphism, Genetic; Prospective Studies; Receptors, Serotonin; Statistics, Nonparametric; Tropisetron; Vomiting | 2003 |
5HT3-receptor antagonists as antiemetics in cancer.
Topics: Adult; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Child; Granisetron; Humans; Indoles; Isoquinolines; Nausea; Neoplasms; Ondansetron; Palonosetron; Practice Guidelines as Topic; Quinolizines; Quinuclidines; Serotonin 5-HT3 Receptor Antagonists; Serotonin Antagonists; Tropisetron; Vomiting | 2005 |
A nonneuronal 5-hydroxytryptamine receptor 3 induces chloride secretion in the rat distal colonic mucosa.
Topics: Analysis of Variance; Animals; Chlorides; Colon; In Vitro Techniques; Indoles; Intestinal Mucosa; Ion Transport; Male; Membrane Potentials; Ondansetron; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin Antagonists; Tetrodotoxin; Tropisetron | 2005 |
Antinociception: mechanistic studies on the action of MD-354 and clonidine. Part 1. The 5-HT3 component.
Topics: Analgesics; Animals; Behavior, Animal; Benzamides; Bridged Bicyclo Compounds, Heterocyclic; Clonidine; Dose-Response Relationship, Drug; Drug Synergism; Guanidines; Indoles; Male; Mice; Mice, Inbred ICR; Models, Animal; Motor Activity; Ondansetron; Pain; Pain Measurement; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Time Factors; Tropisetron | 2005 |
Luminal hypotonicity increases duodenal mucosal permeability by a mechanism involving 5-hydroxytryptamine.
Topics: Anesthetics, Local; Animals; Cyclooxygenase Inhibitors; Duodenum; Granisetron; Indoles; Indomethacin; Intestinal Mucosa; Lidocaine; Male; Ondansetron; Osmotic Pressure; Piperidines; Rats; Rats, Inbred Strains; Serotonin; Serotonin 5-HT3 Receptor Antagonists; Serotonin 5-HT4 Receptor Antagonists; Serotonin Agents; Serotonin Antagonists; Tetrodotoxin; Tropisetron | 2006 |
Effects of dexfenfluramine and 5-HT3 receptor antagonists on stress-induced reinstatement of alcohol seeking in rats.
Topics: Alcoholism; Animals; Dexfenfluramine; Electroshock; Indoles; Male; Ondansetron; Rats; Rats, Wistar; Reinforcement, Psychology; Self Administration; Serotonin 5-HT3 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists; Stress, Psychological; Tropisetron | 2006 |
Phencyclidine-induced cognitive deficits in mice are improved by subsequent subchronic administration of tropisetron: role of alpha7 nicotinic receptors.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Cognition Disorders; Excitatory Amino Acid Antagonists; Indoles; Injections, Subcutaneous; Male; Mice; Mice, Inbred ICR; Ondansetron; Phencyclidine; Receptors, Nicotinic; Recognition, Psychology; Serotonin Antagonists; Tropisetron | 2006 |
Cutaneous adverse drug reactions during chemotherapy: consider non-antineoplastic drugs.
Topics: Adult; Antiemetics; Antineoplastic Agents; Breast Neoplasms; Cross Reactions; Drug Eruptions; Female; Glucocorticoids; Granisetron; Humans; Indoles; Male; Middle Aged; Ondansetron; Pancreatic Neoplasms; Prednisolone; Skin Tests; Tropisetron; Urticaria | 2008 |
Modulation of paracetamol and nefopam antinociception by serotonin 5-HT(3) receptor antagonists in mice.
Topics: Acetaminophen; Acetic Acid; Analgesics; Animals; Drug Interactions; Indoles; Male; Mice; Mice, Inbred Strains; Nefopam; Ondansetron; Pain Measurement; Serotonin 5-HT3 Receptor Antagonists; Serotonin Antagonists; Tropisetron | 2009 |
Tropisetron attenuates naloxone-induced place aversion in single-dose morphine-treated rats: role of alpha7 nicotinic receptors.
Topics: Aconitine; Animals; Conditioning, Psychological; Dose-Response Relationship, Drug; Indoles; Male; Mecamylamine; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Nicotinic Agonists; Nicotinic Antagonists; Ondansetron; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Serotonin Antagonists; Tropisetron | 2009 |
Receptor occupancy theory-based analysis of interindividual differences in antiemetic effects of 5-HT3 receptor antagonists.
Topics: Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Bridged Bicyclo Compounds, Heterocyclic; Drug Administration Schedule; Granisetron; Humans; Indoles; Models, Theoretical; Ondansetron; Oxazines; Serotonin 5-HT3 Receptor Antagonists; Treatment Outcome; Tropisetron; Vomiting | 2009 |
Ameliorating effects of tropisetron on dopaminergic disruption of prepulse inhibition via the alpha(7) nicotinic acetylcholine receptor in Wistar rats.
Topics: Aconitine; Acoustic Stimulation; alpha7 Nicotinic Acetylcholine Receptor; Analysis of Variance; Animals; Apomorphine; Brain; Dopamine; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Indoles; Inhibition, Psychological; Male; Mecamylamine; Models, Biological; Nicotinic Antagonists; Ondansetron; Proto-Oncogene Proteins c-fos; Psychoacoustics; Rats; Rats, Wistar; Receptors, Nicotinic; Reflex, Startle; Serotonin Antagonists; Stereotyped Behavior; Tropisetron | 2010 |
Effects of OCT1 polymorphisms on the cellular uptake, plasma concentrations and efficacy of the 5-HT(3) antagonists tropisetron and ondansetron.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antiemetics; Cell Membrane; Female; HEK293 Cells; Humans; Indoles; Male; Middle Aged; Ondansetron; Organic Cation Transporter 1; Polymorphism, Genetic; Serotonin 5-HT3 Receptor Antagonists; Treatment Outcome; Tropisetron; Young Adult | 2012 |
On-line focusing of 5-hydroxy-tryptamine type 3 receptor antagonists via the combination of field-enhanced sample injection and dynamic pH junction in capillary electrophoresis with amperometric detection.
Topics: Antiemetics; Electrophoresis, Capillary; Female; Humans; Hydrogen-Ion Concentration; Indoles; Limit of Detection; Ondansetron; Serotonin 5-HT3 Receptor Antagonists; Tropisetron | 2014 |
Therapeutic action of 5-HT3 receptor antagonists targeting peritoneal macrophages in post-operative ileus.
Topics: Animals; Anti-Inflammatory Agents; Cytokines; Gastrointestinal Transit; Ileus; Indoles; Isoquinolines; Macrophages, Peritoneal; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Neutrophils; Ondansetron; Palonosetron; Postoperative Complications; Quinuclidines; Receptors, Serotonin, 5-HT3; RNA, Messenger; Serotonin; Serotonin 5-HT3 Receptor Antagonists; Tropisetron | 2015 |
5-HT3 receptor antagonists do not alter spontaneous contraction of pregnant myometrium in vitro.
Topics: Female; Granisetron; Humans; In Vitro Techniques; Indoles; Ondansetron; Pregnancy; Serotonin Antagonists; Tropisetron; Uterine Contraction | 2015 |
5-HT3 receptors antagonists reduce serotonin-induced scratching in mice.
Topics: Animals; Antipruritics; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Indoles; Male; Mice; Ondansetron; Pruritus; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin 5-HT3 Receptor Antagonists; Signal Transduction; Tropisetron | 2015 |
Involvement of nitric oxide-cyclic guanosine monophosphate pathway in the antidepressant-like effect of tropisetron and ondansetron in mice forced swimming test and tail suspension test.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Cyclic GMP; Dose-Response Relationship, Drug; Hindlimb Suspension; Indoles; Locomotion; Male; Mice; Nitric Oxide; Nitrites; Ondansetron; Serotonin Antagonists; Swimming; Tropisetron | 2016 |
Quantification of ondansetron, granisetron and tropisetron in goat plasma using hydrophilic interaction liquid chromatography-solid phase extraction coupled with hydrophilic interaction liquid chromatography-triple quadrupole tandem mass spectrometry.
Topics: Acetonitriles; Animals; Chromatography, Liquid; Formates; Goats; Granisetron; Hydrophobic and Hydrophilic Interactions; Indoles; Linear Models; Ondansetron; Reproducibility of Results; Sensitivity and Specificity; Solid Phase Extraction; Tandem Mass Spectrometry; Tropisetron | 2018 |
PharmGKB summary: Ondansetron and tropisetron pathways, pharmacokinetics and pharmacodynamics.
Topics: Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2D6; Humans; Inactivation, Metabolic; Metabolic Networks and Pathways; Ondansetron; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin Antagonists; Tropisetron | 2019 |
Determination of some antiemetic drugs through its native fluorescence or fluorescence quenching of cerrous ammonium sulphate.
Topics: Ammonium Sulfate; Antiemetics; Chemistry, Pharmaceutical; Fluorometry; Granisetron; Hydrolysis; Ondansetron; Quantum Theory; Radiotherapy; Reproducibility of Results; Spectrometry, Fluorescence; Tropisetron | 2020 |
Tropisetron ameliorates cyclophosphamide-induced hemorrhagic cystitis in rats.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Anti-Inflammatory Agents; Cyclophosphamide; Cystitis; Disease Models, Animal; Female; Granisetron; Hemorrhage; Inflammation Mediators; Lipid Peroxidation; Nicotinic Agonists; Ondansetron; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Poly(ADP-ribose) Polymerases; Rats, Wistar; Serotonin 5-HT3 Receptor Antagonists; Signal Transduction; STAT3 Transcription Factor; Tropisetron; Urinary Bladder | 2020 |
Serotonin type-3 receptor antagonists selectively kill melanoma cells through classical apoptosis, microtubule depolymerisation, ERK activation, and NF-κB downregulation.
Topics: Antiemetics; Apoptosis; Down-Regulation; Humans; Melanoma; Molecular Docking Simulation; NF-kappa B; Ondansetron; Paclitaxel; Serotonin; Tropisetron; Vomiting | 2023 |
The Possible Protective Effects of Ondansetron and Tropisetron on Optic Nerve Crush Injury in Rats.
Topics: Animals; bcl-2-Associated X Protein; Calcineurin; Crush Injuries; Cyclosporine; Indoles; Male; Neuroprotective Agents; Ondansetron; Optic Nerve; Rats; Serotonin; Tropisetron | 2023 |