ondansetron and substance p

ondansetron has been researched along with substance p in 13 studies

Research

Studies (13)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (7.69)	18.7374
1990's	3 (23.08)	18.2507
2000's	5 (38.46)	29.6817
2010's	4 (30.77)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Butler, A; Hagan, RM; Hill, JM; Ireland, SJ; Jordan, CC; Tyers, MB	1
Haga, N; Inatomi, N; Itoh, Z; Mizumoto, A; Shiba, Y; Yamamoto, O	1
Bourdon, V; Damas, J; Liégeois, JF	1
Saphir, A	1
Berggreen, P; Ersbøll, AK; Grøndahl, ML; Hansen, MB; Maltbaek, JS; Skadhauge, E; Thorbøll, JE	1
Black, LS; D'Angelo, R; Dalby, PL; Gesztesi, Z; MacLean, D; Scuderi, PE; Wender, RH; White, PF; Wright, W	1
Aapro, M; Carides, AD; Evans, JK; Hargreaves, R; Hesketh, PJ; Horgan, KJ; Naylor, RJ; Tattersall, FD; Van Belle, S	1
Dickenson, AH; Hunt, SP; Rahman, W; Rygh, LJ; Suzuki, R; Webber, M	1
King, T; Lai, J; Ossipov, MH; Porreca, F; Vanderah, TW; Vera-Portocarrero, LP; Zhang, ET	1
Dubner, R; Guo, W; Lagraize, SC; Ren, K; Wei, F; Yang, K	1
Egashira, N; Kawashiri, T; Kurobe, K; Matsushita, N; Oishi, R; Tatsushima, Y; Yano, T	1
Bazakas, A; Ladizinski, B; Olsen, EA	1
Amagase, K; Horie, S; Kato, S; Matsumoto, K; Utsumi, D	1

Reviews

1 review(s) available for ondansetron and substance p

Article	Year
Differential involvement of neurotransmitters through the time course of cisplatin-induced emesis as revealed by therapy with specific receptor antagonists. European journal of cancer (Oxford, England : 1990), 2003, Volume: 39, Issue:8 Topics: Antiemetics; Antineoplastic Agents; Aprepitant; Cisplatin; Clinical Trials, Phase II as Topic; Drug Therapy, Combination; Granisetron; Humans; Morpholines; Neoplasms; Neurokinin-1 Receptor Antagonists; Neurotransmitter Agents; Ondansetron; Prodrugs; Serotonin; Serotonin Antagonists; Substance P; Vomiting	2003

Article

Year

Differential involvement of neurotransmitters through the time course of cisplatin-induced emesis as revealed by therapy with specific receptor antagonists.

European journal of cancer (Oxford, England : 1990), 2003, Volume: 39, Issue:8

Topics: Antiemetics; Antineoplastic Agents; Aprepitant; Cisplatin; Clinical Trials, Phase II as Topic; Drug Therapy, Combination; Granisetron; Humans; Morpholines; Neoplasms; Neurokinin-1 Receptor Antagonists; Neurotransmitter Agents; Ondansetron; Prodrugs; Serotonin; Serotonin Antagonists; Substance P; Vomiting

2003

Trials

1 trial(s) available for ondansetron and substance p

Article	Year
Substance P (Neurokinin-1) antagonist prevents postoperative vomiting after abdominal hysterectomy procedures. Anesthesiology, 2000, Volume: 93, Issue:4 Topics: Administration, Oral; Adult; Antiemetics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hysterectomy; Injections, Intravenous; Neurokinin-1 Receptor Antagonists; Ondansetron; Piperidines; Placebos; Postoperative Nausea and Vomiting; Preanesthetic Medication; Risk Factors; Serotonin Antagonists; Substance P	2000

Article

Year

Substance P (Neurokinin-1) antagonist prevents postoperative vomiting after abdominal hysterectomy procedures.

Anesthesiology, 2000, Volume: 93, Issue:4

Topics: Administration, Oral; Adult; Antiemetics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hysterectomy; Injections, Intravenous; Neurokinin-1 Receptor Antagonists; Ondansetron; Piperidines; Placebos; Postoperative Nausea and Vomiting; Preanesthetic Medication; Risk Factors; Serotonin Antagonists; Substance P

2000

Other Studies

11 other study(ies) available for ondansetron and substance p

Article	Year
Effect of the 5-HT3 receptor antagonist, GR38032F, on responses to injection of a neurokinin agonist into the ventral tegmental area of the rat brain. European journal of pharmacology, 1987, Jun-19, Volume: 138, Issue:2 Topics: Animals; Dopamine; Imidazoles; Injections; Male; Motor Activity; Nucleus Accumbens; Ondansetron; Peptide Fragments; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Substance P; Tegmentum Mesencephali	1987
Stimulatory mechanism of EM523-induced contractions in postprandial stomach of conscious dogs. Gastroenterology, 1995, Volume: 109, Issue:5 Topics: Animals; Anti-Bacterial Agents; Atropine; Dipeptides; Dogs; Dopamine; Eating; Erythromycin; Hexamethonium; Indoles; Motilin; Muscle Contraction; Naloxone; Ondansetron; Serotonin Antagonists; Stomach; Substance P	1995
Involvement of 5-hydroxytryptamine and bradykinin in the hyperalgesia induced in rats by collagenase from Clostridium histolyticum. Naunyn-Schmiedeberg's archives of pharmacology, 1997, Volume: 355, Issue:5 Topics: Analgesics; Angiotensin-Converting Enzyme Inhibitors; Animals; Behavior, Animal; Bradykinin; Clostridium; Edema; Female; Hindlimb; Hyperalgesia; Indoles; Isoindoles; Kininogens; Lisinopril; Methysergide; Microbial Collagenase; Neurokinin-1 Receptor Antagonists; Ondansetron; Prostaglandins; Rats; Rats, Wistar; Serotonin; Serotonin Antagonists; Substance P	1997
Fighting nausea in the '90s: more and better anti-emetics can help. Journal of the National Cancer Institute, 1997, Sep-03, Volume: 89, Issue:17 Topics: Antiemetics; Antineoplastic Agents; Dexamethasone; Drug Synergism; Drug Therapy, Combination; Granisetron; Humans; Isonipecotic Acids; Nausea; Ondansetron; Serotonin Antagonists; Substance P; Vomiting	1997
Regional differences in neurogenic signal transduction pathway of cholera toxin-induced fluid, electrolyte and serotonin accumulation in the porcine jejunum. Pharmacology & toxicology, 2000, Volume: 86, Issue:6 Topics: Animals; Body Fluids; Cholera Toxin; Dose-Response Relationship, Drug; Electrolytes; Female; Hexamethonium; Jejunum; Nicotinic Antagonists; Ondansetron; Piperidines; Receptors, Neurokinin-1; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin Antagonists; Signal Transduction; Substance P; Swine	2000
Spinal-supraspinal serotonergic circuits regulating neuropathic pain and its treatment with gabapentin. Pain, 2005, Volume: 117, Issue:3 Topics: Action Potentials; Amines; Analgesics; Analysis of Variance; Animals; Behavior, Animal; Cell Count; Cell Death; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Functional Laterality; Gabapentin; gamma-Aminobutyric Acid; Gene Expression Regulation; Hot Temperature; Immunohistochemistry; Male; Neurons; Ondansetron; Pain; Pain Measurement; Pain Threshold; Pokeweed Mitogens; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Neurokinin-1; Ribosome Inactivating Proteins, Type 1; Saporins; Serotonin; Serotonin Antagonists; Spinal Cord; Substance P; Time Factors	2005
Spinal NK-1 receptor expressing neurons mediate opioid-induced hyperalgesia and antinociceptive tolerance via activation of descending pathways. Pain, 2007, Volume: 129, Issue:1-2 Topics: Afferent Pathways; Animals; Drug Tolerance; Dynorphins; Hyperalgesia; Male; Morphine; Neurons; Ondansetron; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Ribosome Inactivating Proteins, Type 1; Saporins; Spinal Cord; Substance P	2007
Spinal cord mechanisms mediating behavioral hyperalgesia induced by neurokinin-1 tachykinin receptor activation in the rostral ventromedial medulla. Neuroscience, 2010, Dec-29, Volume: 171, Issue:4 Topics: Animals; Behavior, Animal; Bridged Bicyclo Compounds, Heterocyclic; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Excitatory Amino Acid Antagonists; Freund's Adjuvant; GABA Agents; Hyperalgesia; In Vitro Techniques; Inflammation; Male; Medulla Oblongata; Membrane Potentials; Microinjections; Muscimol; Ondansetron; Oxazines; Pain Measurement; Pain Threshold; Posterior Horn Cells; Pyridazines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Neurokinin-1; Serotonin Antagonists; Spinal Cord; Substance P; Tryptophan; Up-Regulation	2010
Pemirolast reduces cisplatin-induced kaolin intake in rats. European journal of pharmacology, 2011, Jul-01, Volume: 661, Issue:1-3 Topics: Animals; Antineoplastic Agents; Aprepitant; Biological Transport; Body Weight; Cisplatin; Dexamethasone; Eating; Kaolin; Male; Morpholines; Ondansetron; Pyridines; Pyrimidinones; Rats; Substance P	2011
Aprepitant: a novel neurokinin-1 receptor/substance P antagonist as antipruritic therapy in cutaneous T-cell lymphoma. Journal of the American Academy of Dermatology, 2012, Volume: 67, Issue:5 Topics: Aged; Antipruritics; Aprepitant; Drug Therapy, Combination; Female; Humans; Interferon alpha-2; Interferon-alpha; Lymphoma, T-Cell, Cutaneous; Morpholines; Neurokinin-1 Receptor Antagonists; Ondansetron; Pain Measurement; Recombinant Proteins; Substance P	2012
5-HT3 receptors promote colonic inflammation via activation of substance P/neurokinin-1 receptors in dextran sulphate sodium-induced murine colitis. British journal of pharmacology, 2016, Volume: 173, Issue:11 Topics: Animals; Benzimidazoles; Colitis; Colon; Dextran Sulfate; Dose-Response Relationship, Drug; Inflammation; Male; Mice; Mice, Inbred C57BL; Ondansetron; Receptors, Neurokinin-1; Receptors, Serotonin, 5-HT3; Serotonin 5-HT3 Receptor Antagonists; Structure-Activity Relationship; Substance P	2016