ondansetron and propranolol

ondansetron has been researched along with propranolol in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (13.64)18.2507
2000's8 (36.36)29.6817
2010's11 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Lombardo, F; Obach, RS; Waters, NJ1
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Artursson, P; Mateus, A; Matsson, P1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Adrien, J; Franc, B; Haj-Dahmane, S; Hamon, M; Jolas, T; Lanfumey, L; Tissier, MH1
Becú-Villalobos, D; Lacau-Mengido, IM; Libertun, C1
Gupta, YK; Kacker, V1
Francetic, I; Grabnar, I; Jereb, J; Kozjek, F; Krizman, I; Mrhar, A; Tripkovic, M1
Haga, N; Itoh, Z; Kuwano, H; Mizumoto, A; Mochiki, E; Nomoto, K; Shimura, T; Suzuki, H; Tanaka, T1
Karlson-Stiber, C; Schmidt, A1
da Silva, FC; de Oliveira Citó, Mdo C; de Sousa, FC; de Vasconcelos, SM; Fonteles, MM; Macêdo, DS; Moura, BA; Silva, MI; Woods, DJ1
Gencer, A; Gunduz, O; Ulugol, A1

Reviews

1 review(s) available for ondansetron and propranolol

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for ondansetron and propranolol

ArticleYear
Effects of ondansetron on portal hemodynamics in liver cirrhosis.
    International journal of clinical pharmacology and therapeutics, 2000, Volume: 38, Issue:9

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Double-Blind Method; Female; Hemodynamics; Humans; Hypertension, Portal; Liver Cirrhosis; Male; Middle Aged; Ondansetron; Portal System; Propranolol; Serotonin Antagonists

2000

Other Studies

20 other study(ies) available for ondansetron and propranolol

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:4

    Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software

2009
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
A high-throughput cell-based method to predict the unbound drug fraction in the brain.
    Journal of medicinal chemistry, 2014, Apr-10, Volume: 57, Issue:7

    Topics: Animals; Brain; Dialysis; HEK293 Cells; High-Throughput Screening Assays; Humans; Pharmaceutical Preparations; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2014
Central action of 5-HT3 receptor ligands in the regulation of sleep-wakefulness and raphe neuronal activity in the rat.
    Neuropharmacology, 1992, Volume: 31, Issue:6

    Topics: Animals; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Electrophysiology; Indoles; Male; Neurons; Ondansetron; Propranolol; Pyrimidines; Raphe Nuclei; Rats; Rats, Wistar; Receptors, Serotonin; Reference Values; Serotonin; Serotonin Antagonists; Sleep; Time Factors; Tropanes; Tropisetron; Wakefulness

1992
Different serotonin receptor types participate in 5-hydroxytryptophan-induced gonadotropins and prolactin release in the female infantile rat.
    Neuroendocrinology, 1996, Volume: 63, Issue:5

    Topics: 5-Hydroxytryptophan; Animals; Female; Follicle Stimulating Hormone; Ketanserin; Luteinizing Hormone; Methysergide; Ondansetron; Prolactin; Propranolol; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists

1996
An experimental model to study intracranial hypertension-induced vomiting in conscious dogs.
    Methods and findings in experimental and clinical pharmacology, 1996, Volume: 18, Issue:5

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Behavior, Animal; Disease Models, Animal; Dogs; Female; Intracranial Pressure; Male; Ondansetron; Prazosin; Propranolol; Pseudotumor Cerebri; Serotonin Antagonists; Vomiting

1996
Effect of motilin on endogenous release of insulin in conscious dogs in the fed state.
    Digestive diseases and sciences, 2003, Volume: 48, Issue:12

    Topics: Animals; Atropine; Blood Glucose; Dogs; Dose-Response Relationship, Drug; Duodenum; Gastrointestinal Motility; Hexamethonium; Injections, Intravenous; Insulin; Motilin; Ondansetron; Phentolamine; Postprandial Period; Propranolol; Stomach; Vagus Nerve

2003
Caffeine poisoning and lactate rise: an overlooked toxic effect?
    Acta anaesthesiologica Scandinavica, 2008, Volume: 52, Issue:7

    Topics: Adolescent; Adrenergic beta-Antagonists; Anti-Anxiety Agents; Antidotes; Anxiety; Caffeine; Central Nervous System Stimulants; Charcoal; Female; Gastric Lavage; Humans; Hypokalemia; Lactic Acid; Midazolam; Ondansetron; Propranolol; Rare Diseases; Severity of Illness Index; Suicide, Attempted; Treatment Outcome

2008
Reversal of cocaine withdrawal-induced anxiety by ondansetron, buspirone and propranolol.
    Behavioural brain research, 2012, May-16, Volume: 231, Issue:1

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Buspirone; Cocaine; Male; Motor Activity; Ondansetron; Propranolol; Rats; Rats, Wistar; Substance Withdrawal Syndrome

2012
Involvement of Descending Serotonergic and Noradrenergic Systems and their Spinal Receptor Subtypes in the Antinociceptive Effect of Dipyrone.
    Drug research, 2015, Volume: 65, Issue:12

    Topics: 5,7-Dihydroxytryptamine; Adrenergic Neurons; Analgesics; Animals; Dipyrone; Dose-Response Relationship, Drug; Injections, Spinal; Ketanserin; Mice; Ondansetron; Oxidopamine; Pain Measurement; Piperidines; Prazosin; Propranolol; Receptors, Adrenergic, beta; Receptors, Serotonin; Serotonergic Neurons; Spinal Cord; Sulfonamides; Yohimbine

2015