ondansetron and prochlorperazine

ondansetron has been researched along with prochlorperazine in 39 studies

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's15 (38.46)18.2507
2000's9 (23.08)29.6817
2010's14 (35.90)24.3611
2020's1 (2.56)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Anderson, RF; Hoffman, LG; Ornitz, RD; Scarantino, CW1
van den Berg, AA4
Alexander, E; Bodis, S; Kooy, H; Loeffler, JS1
Fanning, J; Hilgers, RD1
Chen, PP; Critchley, LA; Gin, TA; Ray, AK; Rowbottom, YM; Suen, TK1
Priestman, TJ; Roberts, JT; Upadhyaya, BK1
Priestman, TJ1
Alberts, VA; Catalano, G; Poole, MA1
Corfield, HJ; Eastwood, D; Fear, S; Hadji, F1
Chen, JJ; Frame, DG; White, TJ1
Kwong, WJ; Parasuraman, TV1
Bearman, SI; Cagnoni, PJ; Day, TC; Jones, RB; Matthes, S; Shpall, EJ1
Buerkle, H; Hsu, TY; Lee, TC; Lee, TH; Lin, CR; Mao, CC; Yang, LC1
Choudhry, FM; Hall, BA; Sprung, J1
Chang, P; Chen, J; Frame, D; Okamoto, M1
Amamoo, MA; Bernard, S; Goodin, S; Kane, M; Laliberte, K; Lindley, C; McCune, J; Pham, T; Schell, M; Shord, S; Socinski, MA; Yowell, S1
Roberge, RJ1
Fluder, E; Jellish, WS; Owen, K; Sawicki, K; Sinacore, J1
Amini, R; Hays, DP; Patanwala, AE; Rosen, P1
Trepanier, L1
Haas, DM; Lehmann, AS; McCormick, CL; Renbarger, JL; Rouse, C; Topletz, AR1
Barlow-Savko, E; Carlson, JN; Forehand, B1
Furyk, JS; McKenzie, S; Meek, R1
Bachur, RG; Monuteaux, MC; Neuman, MI1
Byczkowski, T; Chan, S; Kurowski, B; Timm, N1
Gray, R; Lopes, V; Matteson, KA; Mayhall, EA1
Egerton-Warburton, D; Furyk, JS; Meek, RA1
Garra, G; Singer, AJ; Thode, HC1
Gray, M; Kane-Gill, S; Kellum, JA; Priyanka, P; Wang, L1

Reviews

4 review(s) available for ondansetron and prochlorperazine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Antiemetic therapy for nausea and vomiting in the emergency department.
    The Journal of emergency medicine, 2010, Volume: 39, Issue:3

    Topics: Antiemetics; Droperidol; Emergency Service, Hospital; Humans; Metoclopramide; Nausea; Ondansetron; Prochlorperazine; Promethazine; Vomiting

2010
Acute vomiting in cats: rational treatment selection.
    Journal of feline medicine and surgery, 2010, Volume: 12, Issue:3

    Topics: Acute Disease; Animals; Antiemetics; Cat Diseases; Cats; Chlorpromazine; Diarrhea; Famotidine; Indoles; Metoclopramide; Nausea; Ondansetron; Prochlorperazine; Quinolizines; Quinuclidines; Ranitidine; Sucralfate; Vomiting; Weight Loss

2010
Drugs for the treatment of nausea and vomiting in adults in the emergency department setting.
    The Cochrane database of systematic reviews, 2015, Sep-28, Issue:9

    Topics: Adult; Antiemetics; Droperidol; Emergency Service, Hospital; Female; Humans; Male; Metoclopramide; Nausea; Ondansetron; Prochlorperazine; Promethazine; Randomized Controlled Trials as Topic; Visual Analog Scale; Vomiting

2015

Trials

13 trial(s) available for ondansetron and prochlorperazine

ArticleYear
On the mechanism of radiation-induced emesis: the role of serotonin.
    International journal of radiation oncology, biology, physics, 1994, Nov-15, Volume: 30, Issue:4

    Topics: Dexamethasone; Drug Therapy, Combination; Female; Hemibody Irradiation; Humans; Hydroxyindoleacetic Acid; Male; Metoclopramide; Ondansetron; Prochlorperazine; Radiation Injuries; Serotonin; Vomiting

1994
The prevention of radiosurgery-induced nausea and vomiting by ondansetron: evidence of a direct effect on the central nervous system chemoreceptor trigger zone.
    Surgical neurology, 1994, Volume: 42, Issue:3

    Topics: Adult; Aged; Cerebral Ventricles; Female; Humans; Male; Middle Aged; Nausea; Ondansetron; Pilot Projects; Prochlorperazine; Radiosurgery; Retrospective Studies; Treatment Outcome; Vomiting

1994
Ondansetron and metoclopramide fail to prevent vomiting secondary to ultra-high-dose cisplatin-carboplatin chemotherapy.
    Obstetrics and gynecology, 1994, Volume: 83, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cisplatin; Dexamethasone; Diphenhydramine; Drug Therapy, Combination; Endometrial Neoplasms; Female; Humans; Lorazepam; Metoclopramide; Ondansetron; Ovarian Neoplasms; Prochlorperazine; Severity of Illness Index; Single-Blind Method; Treatment Failure; Vomiting

1994
Ondansetron 4 mg for the prevention of nausea and vomiting after minor laparoscopic gynaecological surgery.
    Anaesthesia and intensive care, 1994, Volume: 22, Issue:2

    Topics: Adult; Anesthesia, Inhalation; Anesthesia, Intravenous; Double-Blind Method; Female; Follow-Up Studies; Genitalia, Female; Humans; Laparoscopy; Meperidine; Motion Sickness; Nausea; Ondansetron; Placebos; Premedication; Prochlorperazine; Sterilization, Reproductive; Time Factors; Vomiting

1994
A prospective randomized double-blind trial comparing ondansetron versus prochlorperazine for the prevention of nausea and vomiting in patients undergoing fractionated radiotherapy.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 1993, Volume: 5, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Double-Blind Method; Female; Humans; Male; Middle Aged; Nausea; Neoplasms; Ondansetron; Prochlorperazine; Prospective Studies; Radiotherapy; Vomiting

1993
Comparison of ondansetron and prochlorperazine for the prevention of nausea and vomiting after adenotonsillectomy.
    British journal of anaesthesia, 1996, Volume: 76, Issue:3

    Topics: Adenoidectomy; Adolescent; Adult; Aged; Antiemetics; Child; Child, Preschool; Double-Blind Method; Female; Humans; Injections, Intramuscular; Injections, Intravenous; Male; Middle Aged; Nausea; Ondansetron; Postoperative Complications; Prochlorperazine; Tonsillectomy; Vomiting

1996
A comparison of ondansetron and prochlorperazine for the prevention of nausea and vomiting after tympanoplasty.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1996, Volume: 43, Issue:9

    Topics: Adolescent; Adult; Antiemetics; Child; Double-Blind Method; Female; Humans; Male; Middle Aged; Nausea; Ondansetron; Postoperative Complications; Prochlorperazine; Prospective Studies; Tympanoplasty; Vomiting

1996
The prophylactic antiemetic efficacy of prochlorperazine and ondansetron in nasal septal surgery: a randomized double-blind comparison.
    Anaesthesia and intensive care, 1996, Volume: 24, Issue:5

    Topics: Adolescent; Adult; Anesthesia, General; Antiemetics; Blood Pressure; Child; Double-Blind Method; Female; Headache; Heart Rate; Humans; Incidence; Injections, Intramuscular; Injections, Intravenous; Male; Middle Aged; Nasal Septum; Nausea; Ondansetron; Placebos; Postoperative Complications; Prochlorperazine; Prospective Studies; Rhinoplasty; Vomiting

1996
Efficacy of ondansetron and prochlorperazine for the prevention of postoperative nausea and vomiting after total hip replacement or total knee replacement procedures: a randomized, double-blind, comparative trial.
    Archives of internal medicine, 1998, Oct-26, Volume: 158, Issue:19

    Topics: Adult; Aged; Aged, 80 and over; Antiemetics; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Cost-Benefit Analysis; Double-Blind Method; Female; Hospitals, University; Humans; Incidence; Logistic Models; Male; Middle Aged; Odds Ratio; Ondansetron; Postoperative Nausea and Vomiting; Prochlorperazine; Risk Factors; Severity of Illness Index; Sex Factors; Treatment Outcome; United States

1998
Modification of the pharmacokinetics of high-dose cyclophosphamide and cisplatin by antiemetics.
    Bone marrow transplantation, 1999, Volume: 24, Issue:1

    Topics: Adult; Antiemetics; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Carmustine; Cisplatin; Cross-Linking Reagents; Cyclophosphamide; Dose-Response Relationship, Drug; Female; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Humans; Lorazepam; Lung; Male; Middle Aged; Ondansetron; Prochlorperazine; Radiation-Sensitizing Agents; Retrospective Studies; Transplantation, Autologous

1999
Failure of prevention against postoperative vomiting by ondansetron or prochlorperazine in patients undergoing gynecological laparoscopy.
    Acta anaesthesiologica Sinica, 2000, Volume: 38, Issue:4

    Topics: Adult; Antiemetics; Female; Humans; Laparoscopy; Ondansetron; Postoperative Nausea and Vomiting; Prochlorperazine; Serotonin Antagonists

2000
Prevention of delayed chemotherapy-induced nausea and vomiting after moderately high to highly emetogenic chemotherapy: comparison of ondansetron, prochlorperazine, and dexamethasone.
    American journal of clinical oncology, 2005, Volume: 28, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carboplatin; Cisplatin; Cyclophosphamide; Dexamethasone; Double-Blind Method; Doxorubicin; Female; Humans; Lung Neoplasms; Male; Middle Aged; Nausea; Ondansetron; Paclitaxel; Patient Satisfaction; Prochlorperazine; Serotonin Antagonists; Treatment Outcome; United States; Vomiting

2005
Patient-controlled analgesia combined with either ondansetron or ondansetron plus prochlorperazine for control of pain and nausea and vomiting in patients undergoing abdominal surgery.
    Journal of clinical anesthesia, 2008, Volume: 20, Issue:8

    Topics: Abdomen; Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Antiemetics; Double-Blind Method; Drug Therapy, Combination; Female; Hospitals, University; Humans; Male; Middle Aged; Morphine; Ondansetron; Pain, Postoperative; Postoperative Nausea and Vomiting; Prochlorperazine; Prospective Studies; Time Factors

2008

Other Studies

22 other study(ies) available for ondansetron and prochlorperazine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Which routine antiemetic: ondansetron or prochlorperazine?
    British journal of anaesthesia, 1994, Volume: 73, Issue:2

    Topics: Humans; Ondansetron; Postoperative Complications; Prochlorperazine; Vomiting

1994
Controlling the toxicity of palliative radiotherapy: the role of 5-HT3 antagonists.
    The Canadian journal of oncology, 1996, Volume: 6 Suppl 1

    Topics: Antiemetics; Clinical Trials as Topic; Dopamine Antagonists; Humans; Metoclopramide; Nausea; Neoplasms; Ondansetron; Palliative Care; Prochlorperazine; Quality of Life; Radiotherapy; Serotonin Antagonists; Vomiting

1996
Tardive dyskinesia as a result of long-term prochlorperazine use.
    Southern medical journal, 1996, Volume: 89, Issue:10

    Topics: Antiemetics; Dopamine Antagonists; Dyskinesia, Drug-Induced; Fatal Outcome; Female; Granisetron; Humans; Middle Aged; Nausea; Ondansetron; Prochlorperazine; Time Factors; Vomiting

1996
The impact of audit in a district general hospital on post-operative nausea and vomiting after major gynaecological surgery.
    European journal of anaesthesiology, 1998, Volume: 15, Issue:5

    Topics: Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthesia Department, Hospital; Antiemetics; Attitude of Health Personnel; Cinnarizine; Clinical Protocols; Cyclizine; Droperidol; England; Female; Genitalia, Female; Hospitals, District; Hospitals, General; Humans; Incidence; Logistic Models; Medical Audit; Morphine; Ondansetron; Organizational Policy; Pain, Postoperative; Postoperative Nausea and Vomiting; Prochlorperazine; Retrospective Studies

1998
Cost-effectiveness analysis of oral ondansetron and prochlorperazine for preventing nausea and vomiting after moderately emetogenic chemotherapy.
    Pharmacy practice management quarterly, 1999, Volume: 19, Issue:1

    Topics: Administration, Oral; Antiemetics; Antineoplastic Agents; Clinical Trials as Topic; Cost-Benefit Analysis; Decision Support Techniques; Drug Costs; Humans; Nausea; Ondansetron; Prochlorperazine; Quality-Adjusted Life Years; Retrospective Studies; Treatment Outcome; United States; Vomiting

1999
Extrapyramidal reactions to ondansetron: cross-reactivity between ondansetron and prochlorperazine?
    Anesthesia and analgesia, 2003, Volume: 96, Issue:5

    Topics: Adult; Antiemetics; Basal Ganglia Diseases; Breast Neoplasms; Cross Reactions; Female; Humans; Mastectomy; Middle Aged; Nose; Ondansetron; Plastic Surgery Procedures; Prochlorperazine

2003
Cost-effectiveness analysis of ondansetron and prochlorperazine for the prevention of postoperative nausea and vomiting.
    Journal of managed care pharmacy : JMCP, 2005, Volume: 11, Issue:4

    Topics: Antiemetics; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Cost-Benefit Analysis; Female; Humans; Male; Middle Aged; Ondansetron; Postoperative Nausea and Vomiting; Prochlorperazine; Randomized Controlled Trials as Topic

2005
Antiemetic-related dystonic reaction unmasked by removal of a scopolamine transdermal patch.
    The Journal of emergency medicine, 2006, Volume: 30, Issue:3

    Topics: Administration, Topical; Adult; Antiemetics; Dexamethasone; Dopamine Antagonists; Dystonia; Emergency Service, Hospital; Female; Humans; Metoclopramide; Muscarinic Antagonists; Ondansetron; Postoperative Nausea and Vomiting; Prochlorperazine; Scopolamine

2006
Pharmacogenetic predictors of nausea and vomiting of pregnancy severity and response to antiemetic therapy: a pilot study.
    BMC pregnancy and childbirth, 2013, Jun-20, Volume: 13

    Topics: Adult; Antiemetics; Female; Humans; Metoclopramide; Morning Sickness; Ondansetron; Pilot Projects; Polymorphism, Single Nucleotide; Pregnancy; Pregnancy Trimester, First; Pregnancy Trimester, Second; Prochlorperazine; Promethazine; Receptors, Serotonin, 5-HT3; Severity of Illness Index; Treatment Outcome; Young Adult

2013
Antiemetic use in US EDs.
    The American journal of emergency medicine, 2014, Volume: 32, Issue:1

    Topics: Adolescent; Adult; Aged; Antiemetics; Emergency Service, Hospital; Female; Humans; Male; Metoclopramide; Middle Aged; Ondansetron; Practice Patterns, Physicians'; Prochlorperazine; Promethazine; United States; Young Adult

2014
Drug treatment of adults with nausea and vomiting in primary care.
    BMJ (Clinical research ed.), 2014, Aug-07, Volume: 349

    Topics: Adult; Antiemetics; Domperidone; Droperidol; Female; Histamine Antagonists; Humans; Male; Metoclopramide; Morning Sickness; Muscarinic Antagonists; Nausea; Ondansetron; Pregnancy; Primary Health Care; Prochlorperazine; Promethazine; Scopolamine; Vomiting

2014
A comparison of acute treatment regimens for migraine in the emergency department.
    Pediatrics, 2015, Volume: 135, Issue:2

    Topics: Adolescent; Analgesics; Analgesics, Opioid; Child; Comparative Effectiveness Research; Diphenhydramine; Dopamine Antagonists; Drug Therapy, Combination; Emergency Service, Hospital; Female; Humans; Male; Metoclopramide; Migraine Disorders; Odds Ratio; Ondansetron; Patient Readmission; Prochlorperazine; Recurrence; Retrospective Studies; Risk Assessment; Tryptamines

2015
Intravenous migraine therapy in children with posttraumatic headache in the ED.
    The American journal of emergency medicine, 2015, Volume: 33, Issue:5

    Topics: Adolescent; Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Brain Injuries; Child; Chlorpromazine; Cross-Sectional Studies; Emergency Service, Hospital; Female; Hospitals, Pediatric; Humans; Injections, Intravenous; Ketorolac; Male; Metoclopramide; Migraine Disorders; Ondansetron; Pain Measurement; Prochlorperazine; Retrospective Studies; Tomography, X-Ray Computed; Treatment Outcome; Young Adult

2015
Comparison of antiemetics for nausea and vomiting of pregnancy in an emergency department setting.
    The American journal of emergency medicine, 2015, Volume: 33, Issue:7

    Topics: Adult; Antiemetics; Cohort Studies; Emergency Service, Hospital; Female; Humans; Hypotension, Orthostatic; Ketosis; Length of Stay; Metoclopramide; Morning Sickness; Ondansetron; Pregnancy; Pregnancy Trimester, First; Prochlorperazine; Promethazine; Retrospective Studies; Treatment Outcome; Young Adult

2015
Oligoantiemesis or Inadequate Prescription of Antiemetics in the Emergency Department: A Local and National Perspective.
    The Journal of emergency medicine, 2016, Volume: 50, Issue:6

    Topics: Adult; Antiemetics; Emergency Service, Hospital; Female; Humans; Logistic Models; Male; Metoclopramide; Nausea; Ondansetron; Prochlorperazine; Promethazine; Retrospective Studies; Vomiting

2016
Kidney and Mortality Outcomes Associated with Ondansetron in Critically Ill Patients.
    Journal of intensive care medicine, 2022, Volume: 37, Issue:10

    Topics: Acute Kidney Injury; Antiemetics; Critical Illness; Humans; Intensive Care Units; Kidney; Metoclopramide; Ondansetron; Prochlorperazine

2022