ondansetron and naltrexone

ondansetron has been researched along with naltrexone in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (12.90)18.2507
2000's15 (48.39)29.6817
2010's10 (32.26)24.3611
2020's2 (6.45)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Chaudhry, H; Hofmann, P; Loimer, N1
Le, AD; Sellers, EM1
Bertschy, G; Cucchia, AT; Ferrero, F; Monnat, M; Spagnoli, J1
Matsuzawa, S; Misawa, M; Nagase, H; Suzuki, T1
Ait-Daoud, N; Johnson, BA; Prihoda, TJ1
Ait-Daoud, N; Hargita, ID; Johnson, BA; Prihoda, TJ1
Ait-Daoud, N; Javors, M; Johnson, BA; Roache, JD; Zanca, NA1
Gordon, SM1
Aung, HH; Mehendale, SR; Moss, J; Xie, JT; Yuan, CS1
Blum, HE; Kreisel, W; Opitz, OG; Thimme, R1
Kenna, GA; McGeary, JE; Swift, RM1
Egli, M; Heilig, M1
Johnson, BA2
Berglund, M; Gorelick, D; Hesselbrock, V; Johnson, BA; Kranzler, HR; Möller, HJ; Soyka, M1
Anton, RF; Henderson, S; Li, X; Myrick, H; Randall, PK; Voronin, K1
Kuehn, BM1
De Castro E Silva, E; Ferreira, HS; Fregoneze, JB; Oliveira, EF; Ribeiro, VF1
Hales, TG1
Cicin-Šain, L; Kovak-Mufić, A; Marušić, S; Matošić, A; Vidrih, B1
Barnett, BS; Suzuki, J; Ward, HB1
Alho, H; Castrén, S; Mäkelä, N1
Alto, M; Giusto, A; Greene, MC; Johnson, RM; Kane, J; Lovero, K; McClendon, J; Nicholson, T; Stockton, M; Tol, WA; Wainberg, ML1
Becker, C; Becker, G; Boehlke, C; Buroh, S; Coune, B; Hercz, D; Joos, L; Meerpohl, JJ; Schwarzer, G1

Reviews

11 review(s) available for ondansetron and naltrexone

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Cholestatic liver diseases].
    Therapeutische Umschau. Revue therapeutique, 2004, Volume: 61, Issue:8

    Topics: Anti-Bacterial Agents; Antibodies, Antineutrophil Cytoplasmic; Anticholesteremic Agents; Antipruritics; Autoimmune Diseases; Bile Ducts; Cholagogues and Choleretics; Cholangiography; Cholangitis; Cholangitis, Sclerosing; Cholestasis; Cholestyramine Resin; Clinical Enzyme Tests; Diagnosis, Differential; Hepatitis, Autoimmune; Humans; Immunosuppression Therapy; Inflammatory Bowel Diseases; Liver Cirrhosis; Liver Cirrhosis, Biliary; Liver Transplantation; Naloxone; Naltrexone; Narcotic Antagonists; Ondansetron; Plasmapheresis; Ursodeoxycholic Acid

2004
Pharmacotherapy, pharmacogenomics, and the future of alcohol dependence treatment, Part 2.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2004, Nov-15, Volume: 61, Issue:22

    Topics: Alcohol Deterrents; Alcoholism; Aripiprazole; Behavior Therapy; Disulfiram; Fructose; Humans; Naltrexone; Ondansetron; Pharmacogenetics; Piperazines; Quinolones; Topiramate

2004
Pharmacological treatment of alcohol dependence: target symptoms and target mechanisms.
    Pharmacology & therapeutics, 2006, Volume: 111, Issue:3

    Topics: Acamprosate; Alcohol Deterrents; Alcoholism; Animals; Baclofen; Corticotropin-Releasing Hormone; Disease Models, Animal; Disulfiram; Fructose; Humans; Naltrexone; Neuropeptide Y; Nociceptin; Ondansetron; Opioid Peptides; Receptor, Cannabinoid, CB1; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Taurine; Topiramate

2006
Update on neuropharmacological treatments for alcoholism: scientific basis and clinical findings.
    Biochemical pharmacology, 2008, Jan-01, Volume: 75, Issue:1

    Topics: Acamprosate; Alcoholism; Animals; Baclofen; Disulfiram; Fructose; Humans; Naltrexone; Ondansetron; Receptors, N-Methyl-D-Aspartate; Ritanserin; Selective Serotonin Reuptake Inhibitors; Taurine; Topiramate

2008
World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for Biological Treatment of Substance Use and Related Disorders, Part 1: Alcoholism.
    The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2008, Volume: 9, Issue:1

    Topics: Acamprosate; Alcohol Deterrents; Alcohol-Related Disorders; Biological Psychiatry; Carbamazepine; Disulfiram; Fructose; Health Planning Guidelines; Humans; Naltrexone; Ondansetron; Societies, Scientific; Substance-Related Disorders; Taurine; Topiramate

2008
Medication treatment of different types of alcoholism.
    The American journal of psychiatry, 2010, Volume: 167, Issue:6

    Topics: Adult; Aged; Alcohol Deterrents; Alcoholism; Baclofen; Chronic Disease; Depressive Disorder; Female; Fructose; Humans; Hypothalamo-Hypophyseal System; Limbic System; Male; Naltrexone; Ondansetron; Pituitary-Adrenal System; Prefrontal Cortex; Receptors, Dopamine D2; Receptors, GABA; Topiramate; Young Adult

2010
NEUROBIOLOGICAL BASES OF ALCOHOL ADDICTION.
    Acta clinica Croatica, 2016, Volume: 55, Issue:1

    Topics: Acamprosate; Alcohol Deterrents; Alcoholism; Brain; Disulfiram; Dopamine; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Minisatellite Repeats; Monoamine Oxidase; Naltrexone; Narcotic Antagonists; Neuropeptide Y; Norepinephrine; Ondansetron; Polymorphism, Genetic; Serotonin; Synaptic Transmission; Taurine

2016
Selecting an appropriate alcohol pharmacotherapy: review of recent findings.
    Current opinion in psychiatry, 2019, Volume: 32, Issue:4

    Topics: Acamprosate; Alcoholism; Antidepressive Agents; Baclofen; Cholinergic Agonists; Disulfiram; Gabapentin; Humans; Naltrexone; Ondansetron; Randomized Controlled Trials as Topic; Treatment Outcome

2019
Psychosocial and pharmacologic interventions to reduce harmful alcohol use in low- and middle-income countries.
    The Cochrane database of systematic reviews, 2023, 05-09, Volume: 5

    Topics: Acamprosate; Alcoholism; Amitriptyline; Developing Countries; Disulfiram; Humans; Male; Mirtazapine; Naltrexone; Ondansetron; Topiramate

2023
Pharmacological interventions for pruritus in adult palliative care patients.
    The Cochrane database of systematic reviews, 2023, 04-14, Volume: 4, Issue:2023

    Topics: Animals; Capsaicin; Cromolyn Sodium; gamma-Aminobutyric Acid; Humans; Naltrexone; Ondansetron; Palliative Care; Paroxetine; Receptors, Opioid; Rifampin; Zinc Sulfate

2023

Trials

4 trial(s) available for ondansetron and naltrexone

ArticleYear
Combining ondansetron and naltrexone effectively treats biologically predisposed alcoholics: from hypotheses to preliminary clinical evidence.
    Alcoholism, clinical and experimental research, 2000, Volume: 24, Issue:5

    Topics: Adult; Aged; Alcoholism; Analysis of Variance; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Naltrexone; Narcotic Antagonists; Ondansetron; Serotonin Antagonists

2000
Combining ondansetron and naltrexone reduces craving among biologically predisposed alcoholics: preliminary clinical evidence.
    Psychopharmacology, 2001, Volume: 154, Issue:1

    Topics: Adult; Alcohol Drinking; Alcoholism; Cognitive Behavioral Therapy; Double-Blind Method; Female; Humans; Male; Naltrexone; Narcotic Antagonists; Ondansetron; Serotonin Antagonists

2001
Combining ondansetron and naltrexone treats biological alcoholics: corroboration of self-reported drinking by serum carbohydrate deficient transferrin, a biomarker.
    Alcoholism, clinical and experimental research, 2001, Volume: 25, Issue:6

    Topics: Adult; Alcohol Drinking; Alcoholism; Biomarkers; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Naltrexone; Narcotic Antagonists; Ondansetron; Placebos; Serotonin Antagonists; Transferrin

2001
Effect of naltrexone and ondansetron on alcohol cue-induced activation of the ventral striatum in alcohol-dependent people.
    Archives of general psychiatry, 2008, Volume: 65, Issue:4

    Topics: Adult; Alcoholism; Basal Ganglia; Cerebrovascular Circulation; Cues; Diagnostic and Statistical Manual of Mental Disorders; Female; Humans; Magnetic Resonance Imaging; Male; Naltrexone; Narcotics; Ondansetron; Oxygen; Photic Stimulation; Serotonin Antagonists; Severity of Illness Index

2008

Other Studies

16 other study(ies) available for ondansetron and naltrexone

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
    Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24

    Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility

2010
Ultrashort noninvasive opiate detoxification.
    The American journal of psychiatry, 1993, Volume: 150, Issue:5

    Topics: Adult; Heroin Dependence; Humans; Male; Midazolam; Naloxone; Naltrexone; Ondansetron; Substance Withdrawal Syndrome; Time Factors

1993
Interaction between opiate and 5-HT3 receptor antagonists in the regulation of alcohol intake.
    Alcohol and alcoholism (Oxford, Oxfordshire). Supplement, 1994, Volume: 2

    Topics: Alcohol Drinking; Animals; Drug Synergism; Humans; Male; Mice; Mice, Inbred C57BL; Naltrexone; Narcotic Antagonists; Ondansetron; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Antagonists

1994
Ultra-rapid opiate detoxification using deep sedation with oral midazolam: short and long-term results.
    Drug and alcohol dependence, 1998, Nov-01, Volume: 52, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Anesthesia, General; Clonidine; Drug Therapy, Combination; Feasibility Studies; Female; Follow-Up Studies; Heroin Dependence; Humans; Hypnotics and Sedatives; Length of Stay; Male; Methadone; Midazolam; Naltrexone; Narcotic Antagonists; Neurologic Examination; Ondansetron; Substance Withdrawal Syndrome; Treatment Outcome

1998
Roles of 5-HT3 and opioid receptors in the ethanol-induced place preference in rats exposed to conditioned fear stress.
    Life sciences, 1999, Volume: 64, Issue:21

    Topics: Animals; Conditioning, Psychological; Ethanol; Fear; Male; Naltrexone; Ondansetron; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Stress, Psychological

1999
Does the alcoholic's remedy come in a pill?
    Behavioral healthcare tomorrow, 2001, Volume: 10, Issue:4

    Topics: Acamprosate; Alcohol Deterrents; Alcoholism; Disulfiram; Excitatory Amino Acid Antagonists; Female; Humans; Male; Naltrexone; Narcotic Antagonists; Ondansetron; Patient Compliance; Serotonin Antagonists; Social Support; Taurine; United States

2001
Methylnaltrexone prevents morphine-induced kaolin intake in the rat.
    Life sciences, 2004, Apr-16, Volume: 74, Issue:22

    Topics: Animals; Antiemetics; Diet; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Injections, Intraperitoneal; Kaolin; Male; Morphine; Naltrexone; Narcotic Antagonists; Ondansetron; Pica; Quaternary Ammonium Compounds; Rats; Rats, Wistar

2004
Study suggests gene may predict success of therapies for alcohol dependence.
    JAMA, 2011, Mar-09, Volume: 305, Issue:10

    Topics: Alcoholism; Genetic Predisposition to Disease; Humans; Naltrexone; Narcotic Antagonists; Ondansetron; Predictive Value of Tests; Receptors, Opioid, mu; Serotonin Antagonists; Serotonin Plasma Membrane Transport Proteins; Treatment Outcome

2011
Multiple opioid receptors mediate the hypotensive response induced by central 5-HT(3) receptor stimulation.
    Neuropeptides, 2011, Volume: 45, Issue:3

    Topics: Animals; Biguanides; Blood Pressure; Heart Rate; Hypotension; Male; Naloxone; Naltrexone; Narcotic Antagonists; Ondansetron; Rats; Rats, Wistar; Receptors, Opioid; Receptors, Serotonin, 5-HT3; Serotonin 5-HT3 Receptor Agonists; Serotonin 5-HT3 Receptor Antagonists

2011
Arresting the development of morphine tolerance and dependence.
    British journal of anaesthesia, 2011, Volume: 107, Issue:5

    Topics: Analgesics; Animals; Drug Tolerance; Humans; Ketamine; Morphine Dependence; Naltrexone; Narcotic Antagonists; Ondansetron; Pain; Polypharmacy; Quaternary Ammonium Compounds; Serotonin Antagonists

2011
Rapid transition from methadone to buprenorphine using naltrexone-induced withdrawal: A case report.
    Substance abuse, 2019, Volume: 40, Issue:2

    Topics: Adult; Antidiarrheals; Antiemetics; Antipruritics; Buprenorphine; Clonidine; Deprescriptions; Drug Substitution; Female; Humans; Loperamide; Methadone; Methocarbamol; Muscle Relaxants, Central; Naltrexone; Narcotic Antagonists; Ondansetron; Opiate Substitution Treatment; Opioid-Related Disorders; Promethazine; Substance Withdrawal Syndrome; Sympatholytics

2019