ondansetron and naloxone

ondansetron has been researched along with naloxone in 38 studies

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.63)18.7374
1990's10 (26.32)18.2507
2000's11 (28.95)29.6817
2010's16 (42.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Lombardo, F; Obach, RS; Waters, NJ1
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Andrews, PL; Bingham, S; Joel, SP; Patel, N; Slevin, ML; Thompson, PI1
Higgins, GA; Joharchi, N; Nguyen, P; Sellers, EM1
Dyche, J; Giordano, J1
Haga, N; Inatomi, N; Itoh, Z; Mizumoto, A; Shiba, Y; Yamamoto, O1
Corrigall, WA; Higgins, GA; Sellers, EM; Wang, Y1
Borg, PJ; Taylor, DA1
Essien, E; Thut, PD; Wynn, RL1
Andrews, PL; Davidson, HI1
Chaudhry, H; Hofmann, P; Loimer, N1
Hui, SC; Ogle, CW; Sevilla, EL1
Pinelli, A; Tomasoni, L; Trivulzio, S1
Chen, JH; Lin, HC; Neevel, C1
Evans, SF; Paech, MJ; Wells, J1
Blum, HE; Kreisel, W; Opitz, OG; Thimme, R1
Duman, EN; Erciyes, N; Kadioglu, M; Kalyoncu, NI; Kesim, M; Yaris, E1
Dkhar, SA; Naveen, AT; Peddyreddy, MK; Ramaswamy, S; Shewade, DG1
Bae, HB; Choi, JI; Chung, ST; Kim, CM; Kim, SJ; Yoon, MH1
Kamei, J; Nozaki, C1
Araki, H; Cui, R; Kohnomi, S; Li, B; Suemaru, K1
Adham, AM; Aouad, MT; Dagher, CM; Saasouh, WA; Siddik-Sayyid, SM; Yazbeck-Karam, VG; Zahreddine, BW1
De Castro E Silva, E; Ferreira, HS; Fregoneze, JB; Oliveira, EF; Ribeiro, VF1
Drdla-Schutting, R; Heinl, C; Sandkühler, J; Xanthos, DN1
Frost, J; Spigset, O1
de Groat, WC; Matsuta, Y; Roppolo, JR; Schwen, Z; Shen, B; Tai, C; Wang, J1
Alva, H; Chu, LF; Clark, JD; Clemenson, A; Encisco, E; Erlendson, M; Hoang, D; Lin, JC; Sun, J; Younger, JW1
Carrillo-Munguía, N; Díaz-Reval, MI; González-Trujano, ME; Huerta, M; Trujillo, X1
Fernandes, PD; Giorno, TBS; Pinto, ADC; Silva, BVD1
Almeida, JR; Araújo, AA; Araújo-Filho, HG; Brito, RG; Carvalho, YM; Menezes, PP; Oliveira, MG; Quintans, JS; Quintans-Júnior, LJ; Santos, PL; Scotti, L; Scotti, MT; Serafini, MR; Shanmugam, S; Silva, JC; Thangaraj, P1
Fernandes, PD; Giorno, TBS; Moreira, IGDS; Rezende, CM1

Reviews

2 review(s) available for ondansetron and naloxone

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Cholestatic liver diseases].
    Therapeutische Umschau. Revue therapeutique, 2004, Volume: 61, Issue:8

    Topics: Anti-Bacterial Agents; Antibodies, Antineutrophil Cytoplasmic; Anticholesteremic Agents; Antipruritics; Autoimmune Diseases; Bile Ducts; Cholagogues and Choleretics; Cholangiography; Cholangitis; Cholangitis, Sclerosing; Cholestasis; Cholestyramine Resin; Clinical Enzyme Tests; Diagnosis, Differential; Hepatitis, Autoimmune; Humans; Immunosuppression Therapy; Inflammatory Bowel Diseases; Liver Cirrhosis; Liver Cirrhosis, Biliary; Liver Transplantation; Naloxone; Naltrexone; Narcotic Antagonists; Ondansetron; Plasmapheresis; Ursodeoxycholic Acid

2004

Trials

3 trial(s) available for ondansetron and naloxone

ArticleYear
Intrathecal fentanyl-induced pruritus during labour: the effect of prophylactic ondansetron.
    International journal of obstetric anesthesia, 2004, Volume: 13, Issue:1

    Topics: Adult; Analgesia, Obstetrical; Analgesics, Opioid; Double-Blind Method; Female; Fentanyl; Humans; Injections, Intravenous; Injections, Spinal; Naloxone; Narcotic Antagonists; Ondansetron; Pain; Postoperative Nausea and Vomiting; Pregnancy; Pruritus; Serotonin Antagonists

2004
Ondansetron is as effective as diphenhydramine for treatment of morphine-induced pruritus after cesarean delivery.
    Acta anaesthesiologica Scandinavica, 2010, Volume: 54, Issue:6

    Topics: Adult; Cesarean Section; Diphenhydramine; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Ondansetron; Pain, Postoperative; Patient Satisfaction; Postoperative Nausea and Vomiting; Pregnancy; Pruritus; Recurrence; Serotonin Antagonists; Severity of Illness Index

2010
Acute opioid withdrawal is associated with increased neural activity in reward-processing centers in healthy men: A functional magnetic resonance imaging study.
    Drug and alcohol dependence, 2015, Aug-01, Volume: 153

    Topics: Adult; Brain; Cross-Over Studies; Double-Blind Method; Functional Neuroimaging; Healthy Volunteers; Humans; Magnetic Resonance Imaging; Male; Morphine; Naloxone; Neural Pathways; Ondansetron; Reward; Substance Withdrawal Syndrome

2015

Other Studies

33 other study(ies) available for ondansetron and naloxone

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:4

    Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Morphine 6-glucuronide: a metabolite of morphine with greater emetic potency than morphine in the ferret.
    British journal of pharmacology, 1992, Volume: 106, Issue:1

    Topics: Animals; Cyclophosphamide; Dose-Response Relationship, Drug; Emetics; Ferrets; Granisetron; Imidazoles; Indazoles; Injections, Subcutaneous; Morphine; Morphine Derivatives; Naloxone; Ondansetron; Vomiting

1992
Effects of 5-HT3 receptor antagonists on behavioural measures of naloxone-precipitated opioid withdrawal.
    Psychopharmacology, 1991, Volume: 105, Issue:3

    Topics: Animals; Behavior, Animal; Chlordiazepoxide; Conditioning, Operant; Drug Implants; Imidazoles; Male; Morphine Dependence; Naloxone; Ondansetron; Pyrimidines; Rats; Rats, Inbred Strains; Serotonin Antagonists; Substance Withdrawal Syndrome; Tropanes

1991
Differential analgesic actions of serotonin 5-HT3 receptor antagonists in the mouse.
    Neuropharmacology, 1989, Volume: 28, Issue:4

    Topics: Analgesics; Animals; Imidazoles; Indoles; Injections, Intraventricular; Male; Mice; Mice, Inbred C3H; Naloxone; Nociceptors; Ondansetron; Pain Measurement; Reaction Time; Serotonin Antagonists; Tropanes; Tropisetron

1989
Stimulatory mechanism of EM523-induced contractions in postprandial stomach of conscious dogs.
    Gastroenterology, 1995, Volume: 109, Issue:5

    Topics: Animals; Anti-Bacterial Agents; Atropine; Dipeptides; Dogs; Dopamine; Eating; Erythromycin; Hexamethonium; Indoles; Motilin; Muscle Contraction; Naloxone; Ondansetron; Serotonin Antagonists; Stomach; Substance P

1995
Influence of 5-HT3 receptor antagonists and the indirect 5-HT agonist, dexfenfluramine, on heroin self-administration in rats.
    Psychopharmacology, 1994, Volume: 114, Issue:4

    Topics: Animals; Conditioning, Operant; Fenfluramine; Food; Heroin; Infusions, Intravenous; Male; Naloxone; Ondansetron; Rats; Rats, Wistar; Reinforcement Schedule; Self Administration; Serotonin Antagonists; Serotonin Receptor Agonists; Tropanes

1994
Voluntary oral morphine self-administration in rats: effect of haloperidol or ondansetron.
    Pharmacology, biochemistry, and behavior, 1994, Volume: 47, Issue:3

    Topics: Animals; Behavior, Animal; Defecation; Haloperidol; Injections, Intramuscular; Male; Morphine; Morphine Dependence; Naloxone; Ondansetron; Quinine; Rats; Rats, Wistar; Self Administration; Substance Withdrawal Syndrome

1994
The effects of different antiemetic agents on morphine-induced emesis in ferrets.
    European journal of pharmacology, 1993, Sep-07, Volume: 241, Issue:1

    Topics: Anesthesia; Animals; Antiemetics; Droperidol; Ferrets; Granisetron; Injections, Intravenous; Isoflurane; Male; Metoclopramide; Morphine; Naloxone; Ondansetron; Vomiting

1993
Stimulation of gastrointestinal motility by cisplatin in the ferret: activation of an intrinsic cholinergic mechanism dissociated from emesis.
    Naunyn-Schmiedeberg's archives of pharmacology, 1993, Volume: 347, Issue:5

    Topics: Animals; Atropine; Cisplatin; Female; Ferrets; Gastrointestinal Motility; Male; Muscle Contraction; Muscle, Smooth; Naloxone; Ondansetron; Receptors, Serotonin; Vomiting

1993
Ultrashort noninvasive opiate detoxification.
    The American journal of psychiatry, 1993, Volume: 150, Issue:5

    Topics: Adult; Heroin Dependence; Humans; Male; Midazolam; Naloxone; Naltrexone; Ondansetron; Substance Withdrawal Syndrome; Time Factors

1993
Prevention by the 5-HT3 receptor antagonist, ondansetron, of morphine-dependence and tolerance in the rat.
    British journal of pharmacology, 1996, Volume: 118, Issue:4

    Topics: Animals; Cyproheptadine; Male; Morphine Dependence; Naloxone; Narcotic Antagonists; Ondansetron; Rats; Rats, Sprague-Dawley; Serotonin Antagonists

1996
Effects of ondansetron administration on opioid withdrawal syndrome observed in rats.
    European journal of pharmacology, 1997, Dec-11, Volume: 340, Issue:2-3

    Topics: Animals; Behavior, Animal; Body Temperature; Defecation; Male; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Ondansetron; Pain Measurement; Rats; Rats, Sprague-Dawley; Salivation; Serotonin Antagonists; Substance Withdrawal Syndrome; Urination

1997
Slowing intestinal transit by PYY depends on serotonergic and opioid pathways.
    American journal of physiology. Gastrointestinal and liver physiology, 2004, Volume: 286, Issue:4

    Topics: Animals; Depression, Chemical; Dogs; Gastrointestinal Transit; Naloxone; Narcotic Antagonists; Ondansetron; Peptide YY; Receptors, Opioid; Serotonin; Serotonin Antagonists; Signal Transduction; Synaptic Transmission

2004
The different roles of 5-HT(2) and 5-HT(3) receptors on antinociceptive effect of paroxetine in chemical stimuli in mice.
    Journal of pharmacological sciences, 2005, Volume: 97, Issue:1

    Topics: Abdominal Pain; Acetic Acid; Analgesia; Analgesics; Animals; Dose-Response Relationship, Drug; Drug Synergism; Female; Injections, Intraperitoneal; Ketanserin; Male; Mice; Mice, Inbred BALB C; Morphine; Naloxone; Ondansetron; Pain Measurement; Paroxetine; Receptors, Serotonin, 5-HT2; Receptors, Serotonin, 5-HT3

2005
An inherent acceleratory effect of insulin on small intestinal transit and its pharmacological characterization in normal mice.
    World journal of gastroenterology, 2006, Apr-28, Volume: 12, Issue:16

    Topics: Animals; Atropine; Calcium Channels; Clonidine; Gastrointestinal Transit; Glyburide; Insulin; Insulin Secretion; Intestine, Small; Male; Mice; Naloxone; Ondansetron; Receptors, Opioid; Verapamil

2006
Lack of reciprocity between opioid and 5-HT3 receptors for antinociception in rat spinal cord.
    Pharmacology, 2006, Volume: 77, Issue:4

    Topics: Analgesia; Analgesics, Opioid; Animals; Biguanides; Dose-Response Relationship, Drug; Formaldehyde; Hindlimb; Indazoles; Injections, Spinal; Male; Morphine; Motor Activity; Muscle Tonus; Naloxone; Narcotic Antagonists; Ondansetron; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Receptors, Serotonin, 5-HT3; Serotonin 5-HT3 Receptor Antagonists; Serotonin Receptor Agonists; Spinal Cord; Tropanes

2006
Possible involvement of opioidergic systems in the antinociceptive effect of the selective serotonin reuptake inhibitors in sciatic nerve-injured mice.
    European journal of pharmacology, 2006, Dec-15, Volume: 552, Issue:1-3

    Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Fluvoxamine; Hyperalgesia; Injections, Spinal; Ketanserin; Male; Mice; Mice, Inbred ICR; Naloxone; Narcotic Antagonists; Neuralgia; Ondansetron; Receptors, Opioid; Sciatic Nerve; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Agents; Serotonin Antagonists; Time Factors

2006
Tropisetron attenuates naloxone-induced place aversion in single-dose morphine-treated rats: role of alpha7 nicotinic receptors.
    European journal of pharmacology, 2009, May-01, Volume: 609, Issue:1-3

    Topics: Aconitine; Animals; Conditioning, Psychological; Dose-Response Relationship, Drug; Indoles; Male; Mecamylamine; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Nicotinic Agonists; Nicotinic Antagonists; Ondansetron; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Serotonin Antagonists; Tropisetron

2009
Multiple opioid receptors mediate the hypotensive response induced by central 5-HT(3) receptor stimulation.
    Neuropeptides, 2011, Volume: 45, Issue:3

    Topics: Animals; Biguanides; Blood Pressure; Heart Rate; Hypotension; Male; Naloxone; Naltrexone; Narcotic Antagonists; Ondansetron; Rats; Rats, Wistar; Receptors, Opioid; Receptors, Serotonin, 5-HT3; Serotonin 5-HT3 Receptor Agonists; Serotonin 5-HT3 Receptor Antagonists

2011
Distinct mechanisms underlying pronociceptive effects of opioids.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, Nov-16, Volume: 31, Issue:46

    Topics: 2-Amino-5-phosphonovalerate; Analgesics, Opioid; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Granisetron; Hyperalgesia; Long-Term Potentiation; Male; Naloxone; Narcotic Antagonists; Nerve Fibers, Unmyelinated; Ondansetron; Pain Threshold; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Somatostatin; Spinal Cord; Substance Withdrawal Syndrome; Synaptic Transmission

2011
[Opioid-induced pruritus].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2012, Oct-16, Volume: 132, Issue:19

    Topics: Analgesics, Opioid; Antipruritics; Humans; Injections, Spinal; Naloxone; Ondansetron; Pruritus; Quality of Life; Receptors, Opioid, mu; Serotonin 5-HT3 Receptor Antagonists

2012
Involvement of 5-HT3 receptors in pudendal inhibition of bladder overactivity in cats.
    American journal of physiology. Renal physiology, 2013, Sep-01, Volume: 305, Issue:5

    Topics: Animals; Cats; Electric Stimulation; Female; Male; Naloxone; Ondansetron; Pudendal Nerve; Receptors, Serotonin, 5-HT3; Serotonin 5-HT3 Receptor Antagonists; Urinary Bladder; Urinary Bladder, Overactive

2013
Tramadol and Tramadol+Caffeine Synergism in the Rat Formalin Test Are Mediated by Central Opioid and Serotonergic Mechanisms.
    BioMed research international, 2015, Volume: 2015

    Topics: Analgesics, Opioid; Animals; Caffeine; Dose-Response Relationship, Drug; Drug Synergism; Ketanserin; Naloxone; Ondansetron; Pain; Pain Measurement; Rats; Tramadol

2015
Antinociceptive effect and mechanism of action of isatin, N-methyl isatin and oxopropyl isatin in mice.
    Life sciences, 2016, Apr-15, Volume: 151

    Topics: Analgesics; Animals; Atropine; Dose-Response Relationship, Drug; Isatin; Mecamylamine; Mice; Morphine; Naloxone; NG-Nitroarginine Methyl Ester; Ondansetron; Pain; Pain Measurement

2016
α-Terpineol, a monoterpene alcohol, complexed with β-cyclodextrin exerts antihyperalgesic effect in animal model for fibromyalgia aided with docking study.
    Chemico-biological interactions, 2016, Jul-25, Volume: 254

    Topics: Analgesics; Animals; Behavior, Animal; beta-Cyclodextrins; Binding Sites; Cyclohexane Monoterpenes; Cyclohexenes; Disease Models, Animal; Fibromyalgia; Hyperalgesia; Male; Mice; Molecular Docking Simulation; Monoterpenes; Naloxone; Ondansetron; Protein Structure, Tertiary; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu

2016
New
    Scientific reports, 2018, 07-03, Volume: 8, Issue:1

    Topics: Analgesics; Animals; Behavior, Animal; Capsaicin; Coffee; Disease Models, Animal; Female; Formaldehyde; Glutamic Acid; Hot Temperature; Hyperalgesia; Male; Mice; Naloxone; Narcotic Antagonists; Ondansetron; Pain; Pain Measurement; Piperidines; Pyrazoles; Serotonin

2018