ondansetron and lidocaine

ondansetron has been researched along with lidocaine in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (3.45)18.2507
2000's12 (41.38)29.6817
2010's14 (48.28)24.3611
2020's2 (6.90)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Doman, TN; McGovern, SL; Seidler, J; Shoichet, BK1
Lombardo, F; Obach, RS; Waters, NJ1
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC1
Sen, S; Sinha, N1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Giacomini, KM; Huang, Y; Khuri, N; Kido, Y; Kosaka, A; Morrissey, KM; Sali, A; Wittwer, MB; Zhang, X; Zur, AA1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Artursson, P; Mateus, A; Matsson, P1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Fuchs-Buder, T; Rifat, K; Sansonetti, A; Tramèr, MR1
Chen, FG; Ng, HP; Reddy, MS1
Karamanlioğlu, B; Memiş, D; Pamukçu, Z; Süt, N; Turan, A1
Fassoulaki, A; Melemeni, A; Sarantopoulos, C; Zotou, M1
Nylander, O; Pihl, L1
Akabas, MH; Bali, M; Jansen, M1
Farouk, S1
De Felice, M; Guo, W; King, T; Ossipov, MH; Porreca, F; Wang, R1
Au, H; Badeaux, J; Bonanno, L1
Almeida, A; Amorim, D; Pertovaara, A; Pinto-Ribeiro, F; Viisanen, H; Wei, H1
Matute Crespo, M; Montero Matamala, A1
Hannon, M; Quail, J; Spence, D1
Chaofan, S; Kosem, R; Plansangkate, P; Tanasansuttiporn, J; Termthong, S; Wasinwong, W1
AbdelQadir, YH; Adly, MH; Alnaji, AA; Aly, AA; Ammar, MF; Eguzo, MA; Elfar, WH; Elshanbary, AA; Elsnhory, AB; Farhat, AM; Hamza, MM; Hana, K; Hussein, TA; Mahmoud, AM; Morsy, MH; Shah, J; Shamshoon, KF; Zaazouee, MS1

Reviews

2 review(s) available for ondansetron and lidocaine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Effect of ondansetron compared to lidocaine and placebo for reducing propofol injection pain: A systematic review and meta-analysis of randomized controlled trials.
    Medicine, 2023, Sep-22, Volume: 102, Issue:38

    Topics: Humans; Lidocaine; Ondansetron; Pain, Postoperative; Propofol; Randomized Controlled Trials as Topic

2023

Trials

7 trial(s) available for ondansetron and lidocaine

ArticleYear
Oculocardiac reflex and postoperative vomiting in paediatric strabismus surgery. A randomised controlled trial comparing four anaesthetic techniques.
    Acta anaesthesiologica Scandinavica, 1998, Volume: 42, Issue:1

    Topics: Adolescent; Alfentanil; Analgesics, Opioid; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Anesthetics, Local; Antiemetics; Atropine; Child; Child, Preschool; Confidence Intervals; Elective Surgical Procedures; Hospitalization; Humans; Incidence; Injections, Intravenous; Isoflurane; Lidocaine; Mydriatics; Ondansetron; Postoperative Complications; Propofol; Reflex, Oculocardiac; Risk Factors; Strabismus; Thiopental; Vomiting

1998
Effect of ondansetron pretreatment on pain after rocuronium and propofol injection: a randomised, double-blind controlled comparison with lidocaine.
    Anaesthesia, 2001, Volume: 56, Issue:9

    Topics: Adult; Androstanols; Anesthetics, Intravenous; Anesthetics, Local; Antiemetics; Double-Blind Method; Female; Humans; Injections, Intravenous; Intubation, Intratracheal; Lidocaine; Male; Middle Aged; Neuromuscular Nondepolarizing Agents; Ondansetron; Pain; Pain Measurement; Propofol; Rocuronium; Serotonin Antagonists

2001
The prevention of pain from injection of rocuronium by ondansetron, lidocaine, tramadol, and fentanyl.
    Anesthesia and analgesia, 2002, Volume: 94, Issue:6

    Topics: Adult; Analgesics, Opioid; Androstanols; Anesthetics, Local; Double-Blind Method; Female; Fentanyl; Humans; Injections; Lidocaine; Male; Neuromuscular Nondepolarizing Agents; Ondansetron; Pain; Pain Measurement; Rocuronium; Serotonin Antagonists; Tramadol

2002
Systemic ondansetron antagonizes the sensory block produced by intrathecal lidocaine.
    Anesthesia and analgesia, 2005, Volume: 100, Issue:6

    Topics: Aged; Anesthetics, Local; Antiemetics; Double-Blind Method; Female; Humans; Injections, Spinal; Lidocaine; Male; Nerve Block; Neurons, Afferent; Ondansetron; Pain Measurement; Prospective Studies; Subarachnoid Space; Urinary Bladder Neoplasms

2005
Ondansetron added to lidocaine for intravenous regional anaesthesia.
    European journal of anaesthesiology, 2009, Volume: 26, Issue:12

    Topics: Adult; Anesthesia, Conduction; Anesthetics, Local; Double-Blind Method; Female; Hand; Humans; Injections, Intravenous; Lidocaine; Male; Middle Aged; Motor Activity; Ondansetron; Pain Measurement; Pain, Postoperative; Prospective Studies; Sensation; Serotonin Antagonists; Time Factors

2009
Perioperative Gabapentin Improves Patient-Centered Outcomes After Inguinal Hernia Repair.
    Military medicine, 2017, Volume: 182, Issue:11

    Topics: Adjuvants, Anesthesia; Adult; Amines; Androstanols; Anesthetics, Local; Antiemetics; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Fentanyl; Gabapentin; gamma-Aminobutyric Acid; Hernia, Inguinal; Humans; Hypnotics and Sedatives; Lidocaine; Male; Midazolam; Middle Aged; Neuromuscular Depolarizing Agents; Ondansetron; Placebos; Plastic Surgery Procedures; Propofol; Quality of Life; Rocuronium; Succinylcholine; Treatment Outcome

2017
A comparison of ondansetron and lidocaine in reducing injection pain of propofol: a randomized controlled study.
    BMC anesthesiology, 2022, 04-18, Volume: 22, Issue:1

    Topics: Adolescent; Adult; Aged; Anesthetics, Intravenous; Anesthetics, Local; Double-Blind Method; Humans; Injections, Intravenous; Lidocaine; Middle Aged; Ondansetron; Pain; Pain Measurement; Propofol; Young Adult

2022

Other Studies

20 other study(ies) available for ondansetron and lidocaine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Identification and prediction of promiscuous aggregating inhibitors among known drugs.
    Journal of medicinal chemistry, 2003, Oct-09, Volume: 46, Issue:21

    Topics: Antifungal Agents; beta-Lactamase Inhibitors; Chemical Phenomena; Chemistry, Physical; Chymotrypsin; Enzyme Inhibitors; Kinetics; Light; Malate Dehydrogenase; Models, Molecular; Molecular Conformation; Scattering, Radiation; Structure-Activity Relationship

2003
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:4

    Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software

2009
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
    Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24

    Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility

2010
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Discovery of potent, selective multidrug and toxin extrusion transporter 1 (MATE1, SLC47A1) inhibitors through prescription drug profiling and computational modeling.
    Journal of medicinal chemistry, 2013, Feb-14, Volume: 56, Issue:3

    Topics: Computer Simulation; Fluorescent Dyes; Organic Cation Transport Proteins; Prescription Drugs

2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
A high-throughput cell-based method to predict the unbound drug fraction in the brain.
    Journal of medicinal chemistry, 2014, Apr-10, Volume: 57, Issue:7

    Topics: Animals; Brain; Dialysis; HEK293 Cells; High-Throughput Screening Assays; Humans; Pharmaceutical Preparations; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2014
Luminal hypotonicity increases duodenal mucosal permeability by a mechanism involving 5-hydroxytryptamine.
    Acta physiologica (Oxford, England), 2006, Volume: 186, Issue:1

    Topics: Anesthetics, Local; Animals; Cyclooxygenase Inhibitors; Duodenum; Granisetron; Indoles; Indomethacin; Intestinal Mucosa; Lidocaine; Male; Ondansetron; Osmotic Pressure; Piperidines; Rats; Rats, Inbred Strains; Serotonin; Serotonin 5-HT3 Receptor Antagonists; Serotonin 5-HT4 Receptor Antagonists; Serotonin Agents; Serotonin Antagonists; Tetrodotoxin; Tropisetron

2006
Modular design of Cys-loop ligand-gated ion channels: functional 5-HT3 and GABA rho1 receptors lacking the large cytoplasmic M3M4 loop.
    The Journal of general physiology, 2008, Volume: 131, Issue:2

    Topics: Amino Acid Sequence; Animals; Binding Sites; Cell Line; Cyanobacteria; Diltiazem; Female; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Humans; Intracellular Signaling Peptides and Proteins; Lidocaine; Membrane Potentials; Mice; Molecular Sequence Data; Mutation; Ondansetron; Oocytes; Patch-Clamp Techniques; Picrotoxin; Receptors, GABA-B; Receptors, Serotonin, 5-HT3; Sequence Homology, Amino Acid; Serotonin; Serotonin 5-HT3 Receptor Antagonists; Sodium Chloride; Xenopus laevis

2008
Descending facilitation maintains long-term spontaneous neuropathic pain.
    The journal of pain, 2013, Volume: 14, Issue:8

    Topics: Afferent Pathways; Anesthetics, Local; Animals; Benzodiazepines; Conditioning, Operant; Disease Models, Animal; Hormone Antagonists; Hyperalgesia; Lidocaine; Male; Medulla Oblongata; Neuralgia; Oncogene Proteins v-fos; Ondansetron; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Spinal Nerves; Time Factors

2013
Effectiveness of ondansetron as an adjunct to lidocaine intravenous regional anesthesia on tourniquet pain and postoperative pain in patients undergoing elective hand surgery: a systematic review protocol.
    JBI database of systematic reviews and implementation reports, 2015, Volume: 13, Issue:1

    Topics: Adult; Anesthesia, Conduction; Anesthesia, Intravenous; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Elective Surgical Procedures; Hand; Hand Injuries; Humans; Lidocaine; Ondansetron; Orthopedic Procedures; Pain Measurement; Pain, Postoperative; Serotonin Antagonists; Systematic Reviews as Topic; Tourniquets

2015
Galanin-Mediated Behavioural Hyperalgesia from the Dorsomedial Nucleus of the Hypothalamus Involves Two Independent Descending Pronociceptive Pathways.
    PloS one, 2015, Volume: 10, Issue:11

    Topics: Animals; Arthritis; Behavior, Animal; Disease Models, Animal; Electrophysiology; Galanin; Glutamic Acid; Hyperalgesia; Hypothalamus; Lidocaine; Male; Mediodorsal Thalamic Nucleus; Neurons; Nociception; Ondansetron; Pain; Pressure; Protein Precursors; Rats; Rats, Wistar; Receptors, Serotonin, 5-HT3; Serotonin; Spinal Cord

2015
Pharmacological advances in the multimodal management of perioperative analgesia.
    Revista espanola de anestesiologia y reanimacion, 2017, Volume: 64, Issue:8

    Topics: Analgesia; Analgesics; Analgesics, Opioid; Clinical Trials as Topic; Combined Modality Therapy; Dexmedetomidine; Drug Therapy, Combination; Humans; Ibuprofen; Ketamine; Lidocaine; Magnesium; Ondansetron; Pain Management; Pain, Postoperative; Pregabalin

2017