ondansetron and buspirone

ondansetron has been researched along with buspirone in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19902 (6.25)18.7374
1990's15 (46.88)18.2507
2000's5 (15.63)29.6817
2010's10 (31.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC1
Sen, S; Sinha, N1
Bang-Andersen, B; Frederiksen, K; Hogg, S; Jensen, KG; Jørgensen, M; Mørk, A; Nielsen, SM; Ruhland, T; Smith, G; Stensbøl, TB; Zhong, H1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Giacomini, KM; Huang, Y; Khuri, N; Kido, Y; Kosaka, A; Morrissey, KM; Sali, A; Wittwer, MB; Zhang, X; Zur, AA1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Alton, EW; Geddes, DM; Graham, A1
Barnes, NM; Cheng, CH; Costall, B; Ge, J; Naylor, RJ1
Borsini, F; D'Aranno, V; Lecci, A; Mancinelli, A; Meli, A; Stasi, MA; Volterra, G1
Costall, B; Jones, BJ; Kelly, ME; Naylor, RJ; Oakley, NR; Onaivi, ES; Tyers, MB1
Gardner, CR1
Sussman, N1
Alfieri, AB; Cubeddu, LX1
al-Farhan, M; Andrews, N; File, SE; Wu, PY1
Misawa, M; Mizoguchi, H; Suzuki, T1
Anthony, EW; Nevins, ME1
Meert, TF1
Brawman-Mintzer, O; Mintzer, JE1
Cutler, MG; Jackson, JE; Rodgers, RJ2
Tancer, ME; Uhde, TW1
Costall, B; Neill, JC; Wilson, AW1
Castejón, AM; Cubeddu, LX1
Mahmood, MA; Parnell, M; Voorhees, ME; Zweifler, RM1
Kannan, N; Pal, GK; Pal, P1
Cataldo, S; Chiodera, P; Coiro, V; Maffei, ML; Minelli, R; Vacca, P; Volpi, R; Volta, E1
da Silva, FC; de Oliveira Citó, Mdo C; de Sousa, FC; de Vasconcelos, SM; Fonteles, MM; Macêdo, DS; Moura, BA; Silva, MI; Woods, DJ1
Crum, RM; Hong, H; Mojtabai, R; Stuart, EA; Susukida, R1

Reviews

6 review(s) available for ondansetron and buspirone

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Potential use of drugs modulating 5HT activity in the treatment of anxiety.
    General pharmacology, 1988, Volume: 19, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Buspirone; Humans; Imidazoles; Indoles; Ondansetron; Receptors, Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes

1988
The potential benefits of serotonin receptor-specific agents.
    The Journal of clinical psychiatry, 1994, Volume: 55 Suppl

    Topics: Antidepressive Agents; Buspirone; Depressive Disorder; Humans; Isoxazoles; Ondansetron; Piperazines; Piperidines; Receptors, Serotonin; Risperidone; Selective Serotonin Reuptake Inhibitors; Serotonin; Sumatriptan; Triazoles

1994
Agitation as a possible expression of generalized anxiety disorder in demented elderly patients: toward a treatment approach.
    The Journal of clinical psychiatry, 1996, Volume: 57 Suppl 7

    Topics: Aged; Aggression; Antipsychotic Agents; Anxiety Disorders; Behavior Therapy; Buspirone; Carbamazepine; Clozapine; Combined Modality Therapy; Decision Trees; Dementia; Humans; Ondansetron; Psychomotor Agitation; Serotonin; Trazodone

1996
Role of serotonin drugs in the treatment of social phobia.
    The Journal of clinical psychiatry, 1997, Volume: 58 Suppl 5

    Topics: Buspirone; Clinical Trials as Topic; Double-Blind Method; Fluvoxamine; Humans; Ondansetron; Phobic Disorders; Placebos; Selective Serotonin Reuptake Inhibitors; Serotonin Agents; Treatment Outcome

1997
Comparing pharmacological treatments for cocaine dependence: Incorporation of methods for enhancing generalizability in meta-analytic studies.
    International journal of methods in psychiatric research, 2018, Volume: 27, Issue:4

    Topics: Adult; Anti-Anxiety Agents; Buspirone; Central Nervous System Stimulants; Cocaine-Related Disorders; Female; Humans; Male; Meta-Analysis as Topic; Modafinil; Network Meta-Analysis; Neurotransmitter Agents; Ondansetron; Outcome Assessment, Health Care; Randomized Controlled Trials as Topic; Reserpine

2018

Trials

1 trial(s) available for ondansetron and buspirone

ArticleYear
Comparative efficacy of a single oral dose of ondansetron and of buspirone against cisplatin-induced emesis in cancer patients.
    British journal of cancer, 1995, Volume: 72, Issue:4

    Topics: Administration, Oral; Adult; Antiemetics; Antineoplastic Agents; Buspirone; Cisplatin; Double-Blind Method; Female; Humans; Male; Middle Aged; Ondansetron; Serotonin Antagonists; Vomiting

1995

Other Studies

25 other study(ies) available for ondansetron and buspirone

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:4

    Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software

2009
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
    Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24

    Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility

2010
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
Discovery of 1-[2-(2,4-dimethylphenylsulfanyl)phenyl]piperazine (Lu AA21004): a novel multimodal compound for the treatment of major depressive disorder.
    Journal of medicinal chemistry, 2011, May-12, Volume: 54, Issue:9

    Topics: Animals; Antidepressive Agents; Cell Line; Depressive Disorder, Major; Drug Partial Agonism; Drug Stability; Hippocampus; Humans; In Vitro Techniques; Microsomes, Liver; Oocytes; Piperazines; Radioligand Assay; Rats; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Receptors, Serotonin, 5-HT3; Recombinant Proteins; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT3 Receptor Antagonists; Serotonin Plasma Membrane Transport Proteins; Structure-Activity Relationship; Sulfides; Vortioxetine; Xenopus

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Discovery of potent, selective multidrug and toxin extrusion transporter 1 (MATE1, SLC47A1) inhibitors through prescription drug profiling and computational modeling.
    Journal of medicinal chemistry, 2013, Feb-14, Volume: 56, Issue:3

    Topics: Computer Simulation; Fluorescent Dyes; Organic Cation Transport Proteins; Prescription Drugs

2013
Effects of 5-hydroxytryptamine and 5-hydroxytryptamine receptor agonists on ion transport across mammalian airway epithelia.
    Clinical science (London, England : 1979), 1992, Volume: 83, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amiloride; Animals; Bronchi; Buspirone; Dose-Response Relationship, Drug; Epithelium; Humans; In Vitro Techniques; Ondansetron; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Receptor Agonists; Sheep; Sodium Channels; Trachea

1992
Differential modulation of extracellular levels of 5-hydroxytryptamine in the rat frontal cortex by (R)- and (S)-zacopride.
    British journal of pharmacology, 1992, Volume: 107, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Buspirone; Diazepam; Dose-Response Relationship, Drug; Frontal Lobe; Hydroxyindoleacetic Acid; Male; Ondansetron; Rats; Serotonin; Serotonin Antagonists; Stereoisomerism

1992
Effect of serotoninergic drugs on stress-induced hyperthermia (SIH) in mice.
    Journal of neural transmission. General section, 1990, Volume: 82, Issue:3

    Topics: 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Body Temperature Regulation; Buspirone; Diazepam; Ergolines; Fenclonine; Fever; Flumazenil; Imidazoles; Male; Mice; Ondansetron; Piperazines; Piperidines; Ritanserin; Serotonin; Serotonin Antagonists; Stress, Psychological; Tetrahydronaphthalenes

1990
The effects of ondansetron (GR38032F) in rats and mice treated subchronically with diazepam.
    Pharmacology, biochemistry, and behavior, 1989, Volume: 34, Issue:4

    Topics: Animals; Anti-Anxiety Agents; Avoidance Learning; Buspirone; Darkness; Diazepam; Flumazenil; Imidazoles; Light; Male; Mice; Mice, Inbred Strains; Ondansetron; Rats; Rats, Inbred Strains; Serotonin Antagonists; Social Behavior; Substance Withdrawal Syndrome; Time Factors

1989
The role of 5-HT in the anxiogenic effects of acute ethanol withdrawal and in the long-lasting cognitive deficits.
    Alcohol and alcoholism (Oxford, Oxfordshire). Supplement, 1993, Volume: 2

    Topics: Animals; Anxiety; Buspirone; Cognition Disorders; Ethanol; Exploratory Behavior; Hippocampus; In Vitro Techniques; Male; Memory; Motor Activity; Ondansetron; Potassium; Rats; Receptors, Serotonin; Serotonin; Substance Withdrawal Syndrome

1993
Effects of serotonergic anxiolytics on physical dependence on diazepam in mice.
    Neuroscience letters, 1993, Sep-17, Volume: 160, Issue:1

    Topics: Animals; Anti-Anxiety Agents; Buspirone; Carbolines; Diazepam; Drug Synergism; Epilepsy, Tonic-Clonic; Male; Mice; Mice, Inbred ICR; Ondansetron; Receptors, GABA-A; Serotonin; Substance-Related Disorders

1993
Antagonists at the serotonin-3 receptor can reduce the fear-potentiated startle response in the rat: evidence for different types of anxiolytic activity?
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 268, Issue:1

    Topics: Animals; Anti-Anxiety Agents; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Buspirone; Diazepam; Fear; Granisetron; Male; Ondansetron; Rats; Reflex, Startle; Serotonin Antagonists

1994
Effects of various serotonergic agents on alcohol intake and alcohol preference in Wistar rats selected at two different levels of alcohol preference.
    Alcohol and alcoholism (Oxford, Oxfordshire), 1993, Volume: 28, Issue:2

    Topics: Alcohol Drinking; Alcoholism; Animals; Buspirone; Chlordiazepoxide; Citalopram; Dose-Response Relationship, Drug; Drinking; Fluoxetine; Male; Ondansetron; Rats; Receptors, Serotonin; Ritanserin; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists

1993
Behavioural effects in mice of subchronic buspirone, ondansetron and tianeptine. I. Social interactions.
    Pharmacology, biochemistry, and behavior, 1997, Volume: 56, Issue:2

    Topics: Animals; Antidepressive Agents, Tricyclic; Buspirone; Male; Mice; Ondansetron; Serotonin Receptor Agonists; Social Behavior; Thiazepines

1997
Behavioural effects in mice of subchronic buspirone, ondansetron and tianeptine. II. The elevated plus-maze.
    Pharmacology, biochemistry, and behavior, 1997, Volume: 56, Issue:2

    Topics: Animals; Antidepressive Agents, Tricyclic; Buspirone; Male; Maze Learning; Mice; Ondansetron; Serotonin Receptor Agonists; Thiazepines

1997
An investigation into the effects of 5-HT agonists and receptor antagonists on ethanol self-administration in the rat.
    Alcohol (Fayetteville, N.Y.), 1998, Volume: 16, Issue:3

    Topics: Animals; Buspirone; Dose-Response Relationship, Drug; Ethanol; Female; Fenfluramine; Fluoxetine; Metergoline; Ondansetron; Piperazines; Rats; Rats, Sprague-Dawley; Ritanserin; Selective Serotonin Reuptake Inhibitors; Self Administration; Serotonin Antagonists; Serotonin Receptor Agonists; Time Factors

1998
Level of punishment determines anticonflict activity of ondansetron in pigeons: comparison with buspirone and diazepam.
    Pharmacology, biochemistry, and behavior, 1998, Volume: 61, Issue:4

    Topics: Animals; Anti-Anxiety Agents; Buspirone; Columbidae; Conflict, Psychological; Diazepam; Drug Evaluation, Preclinical; Electroshock; Ondansetron; Punishment; Serotonin Antagonists

1998
Magnesium sulfate increases the rate of hypothermia via surface cooling and improves comfort.
    Stroke, 2004, Volume: 35, Issue:10

    Topics: Adult; Analgesics; Body Temperature; Buspirone; Female; Humans; Hypothermia, Induced; Infusions, Intravenous; Magnesium Sulfate; Male; Meperidine; Middle Aged; Ondansetron; Serotonin Agents

2004
Effects of injection of serotonin into nucleus caudatus on food and water intake and body weight in albino rats.
    Indian journal of physiology and pharmacology, 2004, Volume: 48, Issue:4

    Topics: Animals; Body Weight; Buspirone; Caudate Nucleus; Dose-Response Relationship, Drug; Drinking; Eating; Male; Ondansetron; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin, 5-HT3; Serotonin

2004
Effect of serotonergic system on AVP secretion induced by physical exercise.
    Neuropeptides, 2010, Volume: 44, Issue:1

    Topics: Adult; Arginine Vasopressin; Blood Glucose; Buspirone; Exercise; Hemodynamics; Humans; Male; Ondansetron; Osmolar Concentration; Serotonin; Serotonin Receptor Agonists; Sumatriptan; Young Adult

2010
Reversal of cocaine withdrawal-induced anxiety by ondansetron, buspirone and propranolol.
    Behavioural brain research, 2012, May-16, Volume: 231, Issue:1

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Buspirone; Cocaine; Male; Motor Activity; Ondansetron; Propranolol; Rats; Rats, Wistar; Substance Withdrawal Syndrome

2012