ondansetron and aprepitant

ondansetron has been researched along with aprepitant in 79 studies

Research

Studies (79)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's23 (29.11)29.6817
2010's47 (59.49)24.3611
2020's9 (11.39)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Borms, M; Carides, AD; Cocquyt, V; De Smet, M; Decramer, ML; Eldridge, K; Gertz, BJ; O'Brien, M; Reinhardt, RR; Schellens, JH; Van Aelst, F; Van Belle, S; Verbeke, L1
Brestan, E; Bui, B; Carides, AD; De Smet, M; Decramer, ML; Eldridge, K; Evans, JK; Garin, AM; Gertz, BJ; Lichinitser, MR; Michiels, N; Navari, RM; Reinhardt, RR; Riviere, A; Thant, M; Van Belle, S1
Carides, AD; Chawla, SP; Elmer, ME; Evans, JK; Gralla, RJ; Grunberg, SM; Hesketh, PJ; Horgan, KJ; Rittenberg, C; Schmidt, C; Taylor, A1
Aapro, M; Carides, AD; Evans, JK; Hargreaves, R; Hesketh, PJ; Horgan, KJ; Naylor, RJ; Tattersall, FD; Van Belle, S1
Cai, B; Carides, AD; Chawla, SP; Elmer, M; Grunberg, SM; Horgan, K; Martin, AR; Pearson, JD; Schmidt, C1
Blum, RA; Busillo, J; Goldberg, MR; Gottesdiener, KM; Greenberg, HE; Hesney, M; Hustad, CM; Kraft, WK; Lates, C; Majumdar, A; McCrea, J; Murphy, MG; Orlowski, LH; Panebianco, D; Petty, KJ; Van Buren, S; Waldman, SA1
Beck, K; Carides, AD; Chawla, SP; de Wit, R; Elmer, ME; Evans, JK; Gralla, RJ; Grunberg, SM; Hesketh, PJ; Horgan, KJ; Ianus, J; Reines, S; Roila, F; Warr, DG1
Bohidar, N; Eisenberg, PD; Gabriel, M; Gralla, RJ; Grunberg, SM; Herrstedt, J; Hesketh, PJ; Horgan, KJ; Hustad, CM; Klinger, G; Muss, HB; Raftopoulos, H; Rodgers, A; Skobieranda, F; Warr, DG1
Carides, AD; de Wit, R; Evans, JK; Gralla, RJ; Guoguang-Ma, J; Herrstedt, J; Horgan, KJ; Ianus, J1
Aapro, MS; Ahmed, T; Chan, CY; Giezek, H; Jordan, K; Kim, HK; Park, K; Poli-Bigelli, S; Schmoll, HJ; von Pawel, J1
de Bruijn, P; de Wit, R; Freedman, SJ; Gambale, JJ; Li, S; Loos, WJ; Murphy, GM; Van Dyck, K; van Noort, C; Verweij, J1
Berger, K; Davies, G; Deuson, R; Ehlken, B; Ihbe-Heffinger, A; Krobot, KJ; Lordick, F; Pellissier, J1
Cavaretta, M; Noviasky, J1
Apfel, CC; Carides, AD; Evans, JK; Gan, TJ; Habib, AS; Horgan, KJ; Knighton, J; Kovac, A; Lawson, FC; Minkowitz, H; Philip, BK; Singla, N; Zhang, H1
Carides, AD; Chelly, JE; Diemunsch, P; Eberhart, L; Evans, JK; Gan, TJ; Girao, MJ; Irwin, MG; Lawson, FC; Philip, BK; Pueyo, J; Reiss, T1
Wilkes, G1
Carides, A; Diemunsch, P; Lines, C; McKeon, B; Reiss, T1
Chan, SL; Ho, WM; Hui, EK; Koh, J; Kwan, WH; Lam, KC; Lau, W; Lee, KK; Mo, FK; Mok, TS; Poon, AN; Suen, JJ; Yeo, W; Yeung, WK; Zee, B1
Carides, AD; Chawla, S; Chua, V; Devandry, S; Evans, JK; Gore, L; Hemenway, M; Oxenius, B; Petrilli, A; Schissel, D; Taylor, A; Valentine, J1
Szántó, J; Tóth, J1
Auger, A; Combes, JD; Favier, B; Galy, G; Labidi, SI; Latour, JF; Tissier, F1
Bassam, A; Pikó, B1
Boice, JA; Brown, C; Carides, A; Hardwick, JS; Jordan, K; Rapoport, BL; Schmoll, HJ; Taylor, A; Webb, T1
DiIorio, TM; Hewitt, AM; Parvizi, J; Sharkey, PF1
Carides, AD; Street, JC; Warr, DG1
Carides, AD; Hesketh, PJ; Street, JC; Warr, DG1
Braun, MP; Dean, D; Fedgchin, M; Gargano, C; Gottesdiener, KM; Greenberg, HE; Kraft, WK; Majumdar, A; Murphy, MG; Panebianco, D; Pequignot, E; Petty, KJ; Stoch, SA; Valentine, J1
Borel, CO; Gan, TJ; Habib, AS; Keifer, JC; White, WD1
Beckford, E; Boice, JA; Carides, A; Chua, D; DeVandry, S; Dinis, J; Grunberg, S; Hardwick, JS; Herrstedt, J; Maru, A; Roila, F; Taylor, A1
Egashira, N; Kawashiri, T; Kurobe, K; Matsushita, N; Oishi, R; Tatsushima, Y; Yano, T1
Barnes, LR; Ibinson, JW; Milord, PJ; Phelps, AL; Romeo, RC; Sah, N; Vallejo, MC; Williams, BA1
Barzal, J; Gawronski, K; Mlot, B; Oborska, S; Pielichowski, W; Rzepecki, P; Wasko-Grabowska, A1
Burger, DM; van Herpen, CML; Verwimp-Hoeks, MPA1
Antor, A; Bergese, S; Fernandez, S; Uribe, A; Viloria, A1
Fletcher-Gonzalez, D; Fox-Geiman, MP; Go, A; Kiley, K; Parthasarathy, M; Porter, N; Rodriguez, TE; Rychlik, K; Smith, SE; Stiff, PJ1
Bannerji, R; Kantesaria, B; Mita, M; Poon, J; Shapiro, GI; Small, K; Statkevich, P; Tzontcheva, A; Zhang, D; Zhu, Y1
Bazakas, A; Ladizinski, B; Olsen, EA1
Berger, MJ; Blazer, MA; Crawford, BS; Flynn, JM; Griffith, NL; Layman, RM; Lustberg, MB; Mrozek, E; Phillips, GS; Ramaswamy, B; Shapiro, CL; Wenzell, CM; Wesolowski, R1
Bourdon, F; Duhaut, M; Foulon, C; Lecoeur, M; Odou, P; Vaccher, C1
Goudra, BG; Ochroch, EA; Singh, PM; Sinha, AC; Williams, NW1
Kakiuchi, H; Kawarai-Shimamura, A; Kuwagata, M; Orito, K1
Biondo, L; Bodge, M; Paul, S; Shillingburg, A1
Bourdon, F; Foulon, C; Lecoeur, M; Odou, P; Vaccher, C1
Barrais, L; Castagné, V; Goineau, S; Guillaume, P1
Rapoport, BL1
Preskorn, SH1
Badar, T; Borthakur, G; Cortes, J; Ferrajoli, A; Garcia-Manero, G; Kadia, T; Kantarjian, H; Mattiuzzi, G; O'Brien, S; Poku, R; Wierda, W1
Chow, E; DeAngelis, C; Hunyh, L; McDonald, R; Pasetka, M; Raman, S; Rowbottom, L1
Bakhshi, S; Batra, A; Biswas, B; Dhawan, D; Paul, R; Sreenivas, V1
Du, BX; Liu, M; Shi, XY; Sui, B; Xu, FY; Zhang, H; Zou, Z1
Jahn, F; Jahn, P; Jordan, K; Riesner, A; Sieker, F; Vordermark, D1
Horita, H; Hotta, H; Kato, R; Kitamura, H; Kunishima, Y; Masumori, N; Takahashi, A; Takei, F1
Bouganim, N; Clemons, M; Dranitsaris, G; Mazzarello, S; Smith, S; Vandermeer, L1
Liu, RR; Liu, ZT; Yang, YL; Yang, ZH; Yue, W1
Ahn, JS; Cho, YH; Jang, JS; Kang, JH; Kim, HJ; Kim, JS; Kim, SW; Kim, SY; Kim, YS; Ko, YH; Lee, HW; Lee, NR; Lee, SN; Lee, SR; Park, KU; Shin, SW; Song, EK; Yun, HJ1
Ham, SY; Kim, EH; Lee, JS; Park, WS; Shim, YH; Son, MJ1
Hou, F; Le, Q; Li, H; Li, W; Liu, S; Shi, Q; Zheng, L; Zong, S1
Asada, K; Enomoto, N; Fujisawa, T; Hayakawa, H; Imokawa, S; Inui, N; Karayama, M; Kuroishi, S; Masuda, M; Nakamura, Y; Suda, T; Suzuki, S; Toyoshima, M; Watanabe, H; Yamada, T; Yokomura, K1
Birrer, MJ; Spriggs, DR; Wilbur, MB1
Song, Z; Wang, H; Yang, F; Zhang, H; Zhang, M; Zhao, K1
Bourdon, F; Foulon, C; Kouach, M; Lecoeur, M; Leconte, L; Odou, P; Ultré, V; Vaccher, C1
Ahn, MJ; Cho, CH; Cho, EK; Jang, JS; Jung, H; Kim, DJ; Kim, JE; Kim, JW; Lee, KY; Lee, MA; Lim, MC; Min, KW; Sung, YL; Sym, SJ1
D'Athayde Rodrigues, F; Ferreira, MAP; Moreira, LB; Okumura, LM1
Ades, S; Ashikaga, T; Blackstock, W; Halyard, M; Heimann, R; Kumar, S; Wilson, K1
Kellogg, TA; Martin, EE; Schroeder, DR; Sprung, J; Therneau, IW; Weingarten, TN1
Abbas, N; Abdel-Malek, R; Fawzy, R; Ismail, M; Safwat, E; Salem, DS; Shohdy, KS1
DiCristina, C; Green, S; Kang, HJ; Loftus, S; Pong, A; Zwaan, CM1
Affronti, ML; Desjardins, A; Friedman, HS; Healy, P; Herndon, JE; Lipp, ES; McSherry, F; Miller, E; Patel, MP; Peters, KB; Randazzo, DM; Woodring, S1
Navari, RM1
Burckart, G; Garimella, N; Griebel, D; Heinrichs, MT; Kim, I; Krudys, K; Kumar, S; Mehrotra, N; Momper, JD; Mulberg, AE; Mulugeta, Y; Nelson, R; Reaman, G; Sachs, H; Sinha, V; Yao, L; Zineh, I1
Chan, VT; Cheung, M; Lai, KT; Lam, DC; Lau, TK; Li, L; Mo, FK; Ng, KP; Pang, E; Soo, WM; Suen, JJ; Tang, NL; Tong, M; Tse, T; Wong, A; Yeo, W; Yeung, EW; Yeung, VT1
Akewanlop, C; Danchaivijitr, P; Ithimakin, S; Korphaisarn, K; Laocharoenkiat, A; Nimmannit, A; Soparattanapaisarn, N; Techawattanawanna, S; Theeratrakul, P1
Morio, K; Tsujimoto, Y; Watanabe, J1
Affronti, ML; Herndon, JE; Patel, MP1
Aghazarian, GS; Ghanem, M; Jawad, MA; Lastrapes, L; Lind, R; Motola, D; Perry, M; Singletary, N; Teixeira, AF1
Chen, X; He, H; Hu, W; Liao, Y; Liu, W; Liu, Y; Pan, Z; Wang, X; Zheng, F; Zhong, H1

Reviews

10 review(s) available for ondansetron and aprepitant

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Differential involvement of neurotransmitters through the time course of cisplatin-induced emesis as revealed by therapy with specific receptor antagonists.
    European journal of cancer (Oxford, England : 1990), 2003, Volume: 39, Issue:8

    Topics: Antiemetics; Antineoplastic Agents; Aprepitant; Cisplatin; Clinical Trials, Phase II as Topic; Drug Therapy, Combination; Granisetron; Humans; Morpholines; Neoplasms; Neurokinin-1 Receptor Antagonists; Neurotransmitter Agents; Ondansetron; Prodrugs; Serotonin; Serotonin Antagonists; Substance P; Vomiting

2003
Effects of aprepitant on the pharmacokinetics of ondansetron and granisetron in healthy subjects.
    Clinical therapeutics, 2003, Volume: 25, Issue:5

    Topics: Adult; Antiemetics; Aprepitant; Area Under Curve; Cross-Over Studies; Drug Interactions; Female; Granisetron; Half-Life; Humans; Male; Middle Aged; Morpholines; Ondansetron; Randomized Controlled Trials as Topic

2003
Health outcomes and cost-effectiveness of aprepitant in outpatients receiving antiemetic prophylaxis for highly emetogenic chemotherapy in Germany.
    European journal of cancer (Oxford, England : 1990), 2007, Volume: 43, Issue:2

    Topics: Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Aprepitant; Cisplatin; Clinical Trials, Phase III as Topic; Cost-Benefit Analysis; Dexamethasone; Double-Blind Method; Drug Therapy, Combination; Health Resources; Humans; Morpholines; Multicenter Studies as Topic; Nausea; Neoplasms; Ondansetron; Randomized Controlled Trials as Topic; Treatment Outcome; Vomiting

2007
[Prophylaxis of chemotherapy-induced vomiting and nausea].
    Magyar onkologia, 2008, Volume: 52, Issue:4

    Topics: Adrenal Cortex Hormones; Antiemetics; Antineoplastic Agents; Aprepitant; Granisetron; Humans; Morpholines; Nausea; Neurokinin-1 Receptor Antagonists; Ondansetron; Primary Prevention; Serotonin 5-HT3 Receptor Antagonists; Time Factors; Vomiting

2008
[Treatment of tumor therapy-induced nausea and vomiting].
    Magyar onkologia, 2009, Volume: 53, Issue:1

    Topics: Anti-Anxiety Agents; Antiemetics; Antineoplastic Agents; Aprepitant; Drug Therapy, Combination; Humans; Methylprednisolone; Metoclopramide; Morpholines; Nausea; Neoplasms; Ondansetron; Practice Guidelines as Topic; Selective Serotonin Reuptake Inhibitors; Vomiting

2009
Neurokinin-1 receptor antagonists in preventing postoperative nausea and vomiting: a systematic review and meta-analysis.
    Medicine, 2015, Volume: 94, Issue:19

    Topics: Antiemetics; Aprepitant; Dose-Response Relationship, Drug; Humans; Morpholines; Neurokinin-1 Receptor Antagonists; Ondansetron; Postoperative Nausea and Vomiting; Randomized Controlled Trials as Topic

2015
Prevention of cisplatin-based chemotherapy-induced delayed nausea and vomiting using triple antiemetic regimens: a mixed treatment comparison.
    Oncotarget, 2016, Apr-26, Volume: 7, Issue:17

    Topics: Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Aprepitant; Cisplatin; Dexamethasone; Drug Therapy, Combination; Granisetron; Humans; Isoquinolines; Morpholines; Nausea; Neoplasms; Network Meta-Analysis; Ondansetron; Palonosetron; Quinuclidines; Randomized Controlled Trials as Topic; Spiro Compounds; Treatment Outcome; Vomiting

2016
Aprepitant in pediatric patients using moderate and highly emetogenic protocols: a systematic review and meta-analyses of randomized controlled trials.
    British journal of clinical pharmacology, 2017, Volume: 83, Issue:5

    Topics: Adolescent; Antiemetics; Antineoplastic Agents; Aprepitant; Child; Child, Preschool; Dexamethasone; Drug Therapy, Combination; Humans; Infant; Morpholines; Nausea; Neoplasms; Ondansetron; Randomized Controlled Trials as Topic; Risk Factors; Vomiting; Young Adult

2017
The efficacy of aprepitant for the prevention of postoperative nausea and vomiting: A meta-analysis.
    Medicine, 2023, Jul-21, Volume: 102, Issue:29

    Topics: Antiemetics; Aprepitant; Dexamethasone; Humans; Morpholines; Ondansetron; Postoperative Nausea and Vomiting; Vomiting

2023

Trials

42 trial(s) available for ondansetron and aprepitant

ArticleYear
Comparison of L-758,298, a prodrug for the selective neurokinin-1 antagonist, L-754,030, with ondansetron for the prevention of cisplatin-induced emesis.
    European journal of cancer (Oxford, England : 1990), 2001, Volume: 37, Issue:7

    Topics: Acetals; Adult; Aged; Antiemetics; Antineoplastic Agents; Aprepitant; Cisplatin; Double-Blind Method; Female; Humans; Male; Middle Aged; Morpholines; Nausea; Ondansetron; Patient Satisfaction; Prodrugs; Vomiting

2001
Prevention of cisplatin-induced acute and delayed emesis by the selective neurokinin-1 antagonists, L-758,298 and MK-869.
    Cancer, 2002, Jun-01, Volume: 94, Issue:11

    Topics: Adolescent; Adult; Aged; Antiemetics; Antineoplastic Agents; Aprepitant; Cisplatin; Dexamethasone; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Morpholines; Neoplasms; Neurokinin-1 Receptor Antagonists; Ondansetron; Vomiting

2002
Establishing the dose of the oral NK1 antagonist aprepitant for the prevention of chemotherapy-induced nausea and vomiting.
    Cancer, 2003, May-01, Volume: 97, Issue:9

    Topics: Administration, Oral; Antiemetics; Antineoplastic Agents; Aprepitant; Cisplatin; Dexamethasone; Double-Blind Method; Female; Humans; Injections, Intravenous; Male; Middle Aged; Morpholines; Nausea; Neoplasms; Neurokinin-1 Receptor Antagonists; Ondansetron; Treatment Outcome; Vomiting

2003
Functional relevance of antiemetic control. Experience using the FLIE questionnaire in a randomised study of the NK-1 antagonist aprepitant.
    European journal of cancer (Oxford, England : 1990), 2003, Volume: 39, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antiemetics; Antineoplastic Agents; Aprepitant; Cisplatin; Dexamethasone; Double-Blind Method; Female; Humans; Male; Middle Aged; Morpholines; Nausea; Neoplasms; Ondansetron; Receptors, Neurokinin-1; Surveys and Questionnaires; Vomiting

2003
The oral neurokinin-1 antagonist aprepitant for the prevention of chemotherapy-induced nausea and vomiting: a multinational, randomized, double-blind, placebo-controlled trial in patients receiving high-dose cisplatin--the Aprepitant Protocol 052 Study Gr
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Nov-15, Volume: 21, Issue:22

    Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Antiemetics; Antineoplastic Agents; Aprepitant; Cisplatin; Dexamethasone; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Injections, Intravenous; Male; Middle Aged; Morpholines; Nausea; Neoplasms; Neurokinin-1 Receptor Antagonists; Ondansetron; Placebos; Treatment Outcome; Vomiting

2003
Efficacy and tolerability of aprepitant for the prevention of chemotherapy-induced nausea and vomiting in patients with breast cancer after moderately emetogenic chemotherapy.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Apr-20, Volume: 23, Issue:12

    Topics: Adult; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Aprepitant; Breast Neoplasms; Cyclophosphamide; Dexamethasone; Double-Blind Method; Doxorubicin; Epirubicin; Female; Humans; Middle Aged; Morpholines; Nausea; Ondansetron; Vomiting

2005
Antiemetic efficacy of the neurokinin-1 antagonist, aprepitant, plus a 5HT3 antagonist and a corticosteroid in patients receiving anthracyclines or cyclophosphamide in addition to high-dose cisplatin: analysis of combined data from two Phase III randomize
    Cancer, 2005, Aug-15, Volume: 104, Issue:4

    Topics: Adrenal Cortex Hormones; Anthracyclines; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Aprepitant; Cisplatin; Cyclophosphamide; Dexamethasone; Female; Humans; Male; Morpholines; Nausea; Neoplasms; Neurokinin-1 Receptor Antagonists; Ondansetron; Serotonin 5-HT3 Receptor Antagonists; Vomiting

2005
Comparison of an aprepitant regimen with a multiple-day ondansetron regimen, both with dexamethasone, for antiemetic efficacy in high-dose cisplatin treatment.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2006, Volume: 17, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antiemetics; Antineoplastic Agents; Aprepitant; Cisplatin; Dexamethasone; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Morpholines; Neoplasms; Ondansetron; Patient Selection

2006
A randomized, double-blind comparison of the NK1 antagonist, aprepitant, versus ondansetron for the prevention of postoperative nausea and vomiting.
    Anesthesia and analgesia, 2007, Volume: 104, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aprepitant; Double-Blind Method; Female; Humans; Male; Middle Aged; Morpholines; Neurokinin-1 Receptor Antagonists; Ondansetron; Postoperative Nausea and Vomiting; Receptors, Neurokinin-1

2007
Single-dose aprepitant vs ondansetron for the prevention of postoperative nausea and vomiting: a randomized, double-blind phase III trial in patients undergoing open abdominal surgery.
    British journal of anaesthesia, 2007, Volume: 99, Issue:2

    Topics: Abdomen; Adolescent; Adult; Aged; Aged, 80 and over; Antiemetics; Aprepitant; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Morpholines; Ondansetron; Postoperative Nausea and Vomiting; Severity of Illness Index; Treatment Outcome

2007
A randomized study of aprepitant, ondansetron and dexamethasone for chemotherapy-induced nausea and vomiting in Chinese breast cancer patients receiving moderately emetogenic chemotherapy.
    Breast cancer research and treatment, 2009, Volume: 113, Issue:3

    Topics: Adult; Aged; Antiemetics; Antineoplastic Agents; Aprepitant; Breast Neoplasms; Carcinoma, Ductal, Breast; China; Dexamethasone; Double-Blind Method; Female; Humans; Middle Aged; Morpholines; Nausea; Ondansetron; Quality of Life; Vomiting

2009
Aprepitant in adolescent patients for prevention of chemotherapy-induced nausea and vomiting: a randomized, double-blind, placebo-controlled study of efficacy and tolerability.
    Pediatric blood & cancer, 2009, Volume: 52, Issue:2

    Topics: Adolescent; Antineoplastic Agents; Aprepitant; Area Under Curve; Child; Dexamethasone; Double-Blind Method; Drug-Related Side Effects and Adverse Reactions; Humans; Metabolic Clearance Rate; Morpholines; Nausea; Neutropenia; Ondansetron; Placebos; Treatment Outcome; Vomiting; Young Adult

2009
Aprepitant for the prevention of chemotherapy-induced nausea and vomiting associated with a broad range of moderately emetogenic chemotherapies and tumor types: a randomized, double-blind study.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2010, Volume: 18, Issue:4

    Topics: Adult; Aged; Antiemetics; Antineoplastic Agents; Aprepitant; Dexamethasone; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Morpholines; Nausea; Neoplasms; Ondansetron; Prospective Studies; Treatment Outcome; Vomiting

2010
Evaluation of risk factors predictive of nausea and vomiting with current standard-of-care antiemetic treatment: analysis of phase 3 trial of aprepitant in patients receiving adriamycin-cyclophosphamide-based chemotherapy.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2011, Volume: 19, Issue:6

    Topics: Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Aprepitant; Breast Neoplasms; Breast Neoplasms, Male; Cyclophosphamide; Dexamethasone; Double-Blind Method; Doxorubicin; Drug Therapy, Combination; Female; Humans; Logistic Models; Male; Middle Aged; Morpholines; Multivariate Analysis; Nausea; Neurokinin-1 Receptor Antagonists; Ondansetron; Prognosis; Risk Factors; Vomiting

2011
Differential time course of action of 5-HT3 and NK1 receptor antagonists when used with highly and moderately emetogenic chemotherapy (HEC and MEC).
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2011, Volume: 19, Issue:9

    Topics: Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Aprepitant; Cisplatin; Dexamethasone; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Logistic Models; Male; Middle Aged; Morpholines; Multivariate Analysis; Nausea; Neoplasms; Neurokinin-1 Receptor Antagonists; Ondansetron; Serotonin 5-HT3 Receptor Antagonists; Time Factors; Vomiting

2011
Double-blind crossover study to assess potential differences in cytochrome P450 3A4 activity in healthy subjects receiving ondansetron plus dexamethasone, with and without aprepitant.
    Cancer chemotherapy and pharmacology, 2011, Volume: 67, Issue:6

    Topics: Adult; Antiemetics; Aprepitant; Cross-Over Studies; Cytochrome P-450 CYP3A; Dexamethasone; Double-Blind Method; Drug Interactions; Female; Humans; Male; Midazolam; Morpholines; Ondansetron

2011
A comparison of the combination of aprepitant and dexamethasone versus the combination of ondansetron and dexamethasone for the prevention of postoperative nausea and vomiting in patients undergoing craniotomy.
    Anesthesia and analgesia, 2011, Volume: 112, Issue:4

    Topics: Adult; Aprepitant; Craniotomy; Dexamethasone; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Morpholines; Ondansetron; Postoperative Nausea and Vomiting; Prospective Studies

2011
Single-dose fosaprepitant for the prevention of chemotherapy-induced nausea and vomiting associated with cisplatin therapy: randomized, double-blind study protocol--EASE.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Apr-10, Volume: 29, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Antiemetics; Antineoplastic Agents; Aprepitant; Cisplatin; Dexamethasone; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Morpholines; Nausea; Ondansetron; Treatment Outcome; Vomiting

2011
Aprepitant plus ondansetron compared with ondansetron alone in reducing postoperative nausea and vomiting in ambulatory patients undergoing plastic surgery.
    Plastic and reconstructive surgery, 2012, Volume: 129, Issue:2

    Topics: Adult; Ambulatory Surgical Procedures; Antiemetics; Aprepitant; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Morpholines; Ondansetron; Plastic Surgery Procedures; Postoperative Nausea and Vomiting; Prospective Studies

2012
A triple-drug combination to prevent nausea and vomiting following BEAM chemotherapy before autologous hematopoietic stem cell transplantation.
    Transplantation proceedings, 2011, Volume: 43, Issue:8

    Topics: Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Aprepitant; Carmustine; Cytarabine; Dexamethasone; Drug Therapy, Combination; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Hodgkin Disease; Humans; Isoquinolines; Lymphoma, Non-Hodgkin; Male; Melphalan; Morpholines; Nausea; Ondansetron; Palonosetron; Quinuclidines; Transplantation, Autologous; Treatment Outcome; Vomiting

2011
Aprepitant versus ondansetron in preoperative triple-therapy treatment of nausea and vomiting in neurosurgery patients: study protocol for a randomized controlled trial.
    Trials, 2012, Aug-03, Volume: 13

    Topics: Antiemetics; Aprepitant; Dexamethasone; Double-Blind Method; Drug Therapy, Combination; Humans; Morpholines; Neurosurgical Procedures; Ohio; Ondansetron; Postoperative Nausea and Vomiting; Promethazine; Research Design; Treatment Outcome

2012
Prevention of nausea and vomiting associated with stem cell transplant: results of a prospective, randomized trial of aprepitant used with highly emetogenic preparative regimens.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2013, Volume: 19, Issue:1

    Topics: Adult; Aged; Antiemetics; Aprepitant; Dexamethasone; Female; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Humans; Male; Middle Aged; Morpholines; Ondansetron; Postoperative Nausea and Vomiting; Prospective Studies; Severity of Illness Index; Transplantation, Autologous; Transplantation, Homologous

2013
Effect of aprepitant on the pharmacokinetics of the cyclin-dependent kinase inhibitor dinaciclib in patients with advanced malignancies.
    Cancer chemotherapy and pharmacology, 2012, Volume: 70, Issue:6

    Topics: Administration, Oral; Adult; Aged; Analysis of Variance; Antiemetics; Antineoplastic Agents; Aprepitant; Area Under Curve; Bridged Bicyclo Compounds, Heterocyclic; Cross-Over Studies; Cyclic N-Oxides; Cyclin-Dependent Kinases; Dexamethasone; Drug Administration Schedule; Female; Half-Life; Humans; Indolizines; Infusions, Intravenous; Linear Models; Male; Middle Aged; Morpholines; Nausea; Neoplasms; Ondansetron; Pyridinium Compounds; Treatment Failure; Vomiting

2012
Pilot study on the efficacy of an ondansetron- versus palonosetron-containing antiemetic regimen prior to highly emetogenic chemotherapy.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2013, Volume: 21, Issue:10

    Topics: Adult; Aged; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Aprepitant; Breast Neoplasms; Cyclophosphamide; Dexamethasone; Doxorubicin; Female; Humans; Isoquinolines; Middle Aged; Morpholines; Nausea; Ondansetron; Palonosetron; Pilot Projects; Prospective Studies; Quinuclidines; Vomiting

2013
Aprepitant's prophylactic efficacy in decreasing postoperative nausea and vomiting in morbidly obese patients undergoing bariatric surgery.
    Obesity surgery, 2014, Volume: 24, Issue:2

    Topics: Adult; Antiemetics; Aprepitant; Bariatric Surgery; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Laparoscopy; Male; Middle Aged; Morpholines; Obesity, Morbid; Ondansetron; Patient Satisfaction; Postoperative Nausea and Vomiting; Prospective Studies; Treatment Outcome

2014
Safety and efficacy of aprepitant for chemotherapy-induced nausea and vomiting in pediatric patients: a prospective, observational study.
    Pediatric blood & cancer, 2014, Volume: 61, Issue:6

    Topics: Adolescent; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Aprepitant; Body Weight; Child; Child, Preschool; Dexamethasone; Drug Therapy, Combination; Female; Humans; Incidence; Infant; Male; Morpholines; Nausea; Neoplasms; Ondansetron; Prospective Studies; Remission Induction; Severity of Illness Index; Treatment Outcome; Vomiting

2014
Efficacy of a triple antiemetic regimen with aprepitant for the prevention of chemotherapy-induced nausea and vomiting: effects of gender, age, and region.
    Current medical research and opinion, 2014, Volume: 30, Issue:9

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Antiemetics; Antineoplastic Agents; Aprepitant; Dexamethasone; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Morpholines; Nausea; Ondansetron; Prospective Studies; Sex Factors; Treatment Outcome; Vomiting; Young Adult

2014
Phase II, open label, randomized comparative trial of ondansetron alone versus the combination of ondansetron and aprepitant for the prevention of nausea and vomiting in patients with hematologic malignancies receiving regimens containing high-dose cytara
    BioMed research international, 2015, Volume: 2015

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Aprepitant; Cytarabine; Dose-Response Relationship, Drug; Female; Hematologic Neoplasms; Humans; Male; Middle Aged; Morpholines; Nausea; Ondansetron; Treatment Outcome; Vomiting

2015
Aprepitant as an add-on therapy in children receiving highly emetogenic chemotherapy: a randomized, double-blind, placebo-controlled trial.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2015, Volume: 23, Issue:11

    Topics: Administration, Intravenous; Adolescent; Anti-Inflammatory Agents; Antiemetics; Aprepitant; Child; Child, Preschool; Dexamethasone; Double-Blind Method; Female; Humans; Induction Chemotherapy; Male; Morpholines; Nausea; Neoplasms; Neurokinin-1 Receptor Antagonists; Ondansetron; Ontario; Remission Induction; Serotonin 5-HT3 Receptor Antagonists; Vomiting

2015
Addition of the Neurokinin-1-Receptor Antagonist (RA) Aprepitant to a 5-Hydroxytryptamine-RA and Dexamethasone in the Prophylaxis of Nausea and Vomiting Due to Radiation Therapy With Concomitant Cisplatin.
    International journal of radiation oncology, biology, physics, 2015, Aug-01, Volume: 92, Issue:5

    Topics: Antiemetics; Antineoplastic Agents; Aprepitant; Chemoradiotherapy; Cisplatin; Dexamethasone; Drug Therapy, Combination; Esophageal Neoplasms; Female; Head and Neck Neoplasms; Humans; Indoles; Lung Neoplasms; Male; Middle Aged; Morpholines; Nausea; Neurokinin-1 Receptor Antagonists; Ondansetron; Prospective Studies; Serotonin Antagonists; Tropisetron; Uterine Cervical Neoplasms; Vomiting

2015
Measuring the impact of guideline-based antiemetic therapy on nausea and vomiting control in breast cancer patients with multiple risk factors.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2016, Volume: 24, Issue:4

    Topics: Adult; Aged; Antiemetics; Antineoplastic Agents; Aprepitant; Breast Neoplasms; Dexamethasone; Female; Humans; Middle Aged; Morpholines; Nausea; Ondansetron; Outcome Assessment, Health Care; Practice Guidelines as Topic; Risk Factors; Vomiting

2016
Ramosetron Versus Ondansetron in Combination With Aprepitant and Dexamethasone for the Prevention of Highly Emetogenic Chemotherapy-Induced Nausea and Vomiting: A Multicenter, Randomized Phase III Trial, KCSG PC10-21.
    The oncologist, 2015, Volume: 20, Issue:12

    Topics: Aged; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Aprepitant; Benzimidazoles; Dexamethasone; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Morpholines; Nausea; Neoplasms; Ondansetron; Prospective Studies; Single-Blind Method; Treatment Outcome; Vomiting

2015
Aprepitant for antiemesis after laparoscopic gynaecological surgery: A randomised controlled trial.
    European journal of anaesthesiology, 2016, Volume: 33, Issue:2

    Topics: Administration, Intravenous; Administration, Oral; Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Antiemetics; Aprepitant; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Fentanyl; Gynecologic Surgical Procedures; Hospitals, University; Humans; Kaplan-Meier Estimate; Laparoscopy; Middle Aged; Morpholines; Neurokinin-1 Receptor Antagonists; Ondansetron; Postoperative Nausea and Vomiting; Republic of Korea; Serotonin Antagonists; Time Factors; Treatment Outcome; Young Adult

2016
Sequential addition of aprepitant in patients receiving carboplatin-based chemotherapy.
    Medical oncology (Northwood, London, England), 2016, Volume: 33, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antiemetics; Antineoplastic Agents; Aprepitant; Bevacizumab; Carboplatin; Carcinoma, Non-Small-Cell Lung; Dexamethasone; Female; Granisetron; Humans; Lung Neoplasms; Male; Middle Aged; Morpholines; Nausea; Ondansetron; Paclitaxel; Pemetrexed; Vomiting

2016
Efficacy and safety of triple therapy with aprepitant, ondansetron, and prednisone for preventing nausea and vomiting induced by R-CEOP or CEOP chemotherapy regimen for non-Hodgkin lymphoma: a phase 2 open-label, randomized comparative trial.
    Leukemia & lymphoma, 2017, Volume: 58, Issue:4

    Topics: Activities of Daily Living; Adult; Antineoplastic Combined Chemotherapy Protocols; Aprepitant; Drug Therapy, Combination; Female; Humans; Lymphoma, Non-Hodgkin; Male; Middle Aged; Morpholines; Nausea; Ondansetron; Prednisone; Quality of Life; Treatment Outcome; Vomiting

2017
Efficacy and safety of aprepitant for the prevention of chemotherapy-induced nausea and vomiting during the first cycle of moderately emetogenic chemotherapy in Korean patients with a broad range of tumor types.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2017, Volume: 25, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Aprepitant; Cyclophosphamide; Dexamethasone; Double-Blind Method; Female; Humans; Male; Middle Aged; Morpholines; Nausea; Neoplasms; Ondansetron; Vomiting; Young Adult

2017
Effectiveness of aprepitant in addition to ondansetron in the prevention of nausea and vomiting caused by fractionated radiotherapy to the upper abdomen (AVERT).
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2017, Volume: 25, Issue:5

    Topics: Abdomen; Aged; Antiemetics; Aprepitant; Dose Fractionation, Radiation; Female; Humans; Male; Middle Aged; Morpholines; Nausea; Ondansetron; Radiotherapy; Vomiting

2017
Addition of 3-day aprepitant to ondansetron and dexamethasone for prophylaxis of chemotherapy-induced nausea and vomiting among patients with diffuse large B cell lymphoma receiving 5-day cisplatin-based chemotherapy.
    Journal of the Egyptian National Cancer Institute, 2017, Volume: 29, Issue:3

    Topics: Adult; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Aprepitant; Chemoprevention; Cisplatin; Dexamethasone; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Lymphoma, Large B-Cell, Diffuse; Male; Middle Aged; Morpholines; Nausea; Ondansetron; Pilot Projects; Time Factors; Treatment Outcome; Vomiting

2017
Aprepitant for the prevention of chemotherapy-induced nausea and vomiting in paediatric subjects: An analysis by age group.
    Pediatric blood & cancer, 2018, Volume: 65, Issue:10

    Topics: Adolescent; Age Factors; Antiemetics; Antineoplastic Agents; Aprepitant; Child; Child, Preschool; Double-Blind Method; Female; Humans; Infant; Male; Nausea; Neoplasms; Ondansetron; Vomiting

2018
Randomized open-label phase II trial of 5-day aprepitant plus ondansetron compared to ondansetron alone in the prevention of chemotherapy-induced nausea-vomiting (CINV) in glioma patients receiving adjuvant temozolomide.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2020, Volume: 28, Issue:5

    Topics: Adult; Aged; Antiemetics; Antineoplastic Agents; Aprepitant; Brain Neoplasms; Female; Glioma; Humans; Male; Middle Aged; Nausea; Ondansetron; Quality of Life; Temozolomide; Vomiting

2020
A randomized study of olanzapine-containing versus standard antiemetic regimens for the prevention of chemotherapy-induced nausea and vomiting in Chinese breast cancer patients.
    Breast (Edinburgh, Scotland), 2020, Volume: 50

    Topics: Adult; Aged; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Aprepitant; Breast Neoplasms; China; Cyclophosphamide; Dexamethasone; Doxorubicin; Female; Humans; Middle Aged; Nausea; Olanzapine; Ondansetron; Vomiting

2020
Randomized, double-blind, placebo-controlled study of aprepitant versus two dosages of olanzapine with ondansetron plus dexamethasone for prevention of chemotherapy-induced nausea and vomiting in patients receiving high-emetogenic chemotherapy.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2020, Volume: 28, Issue:11

    Topics: Adult; Aged; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Aprepitant; Chemoprevention; Cisplatin; Cyclophosphamide; Dexamethasone; Dose-Response Relationship, Drug; Double-Blind Method; Doxorubicin; Drug Therapy, Combination; Emetics; Female; Humans; Induction Chemotherapy; Male; Middle Aged; Nausea; Neoplasms; Olanzapine; Ondansetron; Placebos; Quality of Life; Treatment Outcome; Vomiting; Young Adult

2020

Other Studies

27 other study(ies) available for ondansetron and aprepitant

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Aprepitant when added to a standard antiemetic regimen consisting of ondansetron and dexamethasone does not affect vinorelbine pharmacokinetics in cancer patients.
    Cancer chemotherapy and pharmacology, 2007, Volume: 59, Issue:3

    Topics: Antiemetics; Antineoplastic Agents, Phytogenic; Aprepitant; Area Under Curve; Cross-Over Studies; Dexamethasone; Drug Therapy, Combination; Female; Half-Life; Humans; Infusions, Intravenous; Male; Middle Aged; Morpholines; Neoplasms; Ondansetron; Vinblastine; Vinorelbine

2007
Study flaw in comparisons of aprepitant and ondansetron.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2007, Feb-15, Volume: 64, Issue:4

    Topics: Antiemetics; Aprepitant; Clinical Trials as Topic; Humans; Morpholines; Ondansetron; Postoperative Nausea and Vomiting; Research Design

2007
Antiemetic agents.
    Oncology (Williston Park, N.Y.), 2007, Volume: 21, Issue:8 Suppl

    Topics: Administration, Oral; Anorexia; Antiemetics; Antineoplastic Agents; Aprepitant; Asthenia; Constipation; Diarrhea; Drug Interactions; Dyspepsia; Fatigue; Fever; Granisetron; Headache; Hiccup; Humans; Indoles; Injections, Intravenous; Isoquinolines; Morpholines; Nausea; Neoplasms; Ondansetron; Palonosetron; Quinolizines; Quinuclidines; Vomiting

2007
Comparisons of aprepitant and ondansetron.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2007, Dec-01, Volume: 64, Issue:23

    Topics: Antiemetics; Aprepitant; Chemoprevention; Clinical Trials, Phase III as Topic; Humans; Morpholines; Ondansetron; Postoperative Nausea and Vomiting; Treatment Outcome

2007
[Aprepitant for the prevention of cisplatine induced nausea and vomiting: an observational study].
    Bulletin du cancer, 2009, Volume: 96, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antiemetics; Antineoplastic Agents; Aprepitant; Cisplatin; Female; Humans; Male; Middle Aged; Morpholines; Nausea; Ondansetron; Prednisolone; Prospective Studies; Vomiting

2009
Antiemesis after total joint arthroplasty: does a single preoperative dose of aprepitant reduce nausea and vomiting?
    Clinical orthopaedics and related research, 2010, Volume: 468, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Antiemetics; Aprepitant; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Case-Control Studies; Drug Administration Schedule; Female; Humans; Length of Stay; Male; Middle Aged; Morpholines; Ondansetron; Postoperative Nausea and Vomiting; Preoperative Care; Retrospective Studies; Severity of Illness Index; Time Factors; Treatment Outcome

2010
Pemirolast reduces cisplatin-induced kaolin intake in rats.
    European journal of pharmacology, 2011, Jul-01, Volume: 661, Issue:1-3

    Topics: Animals; Antineoplastic Agents; Aprepitant; Biological Transport; Body Weight; Cisplatin; Dexamethasone; Eating; Kaolin; Male; Morpholines; Ondansetron; Pyridines; Pyrimidinones; Rats; Substance P

2011
Aprepitant quetiapine: a clinically significant drug interaction in a patient treated for head and neck cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2012, Volume: 23, Issue:3

    Topics: Adult; Antidepressive Agents; Antiemetics; Antineoplastic Agents; Aprepitant; Carcinoma; Chemoradiotherapy; Cisplatin; Citalopram; Depression; Dexamethasone; Dibenzothiazepines; Drug Interactions; Humans; Laryngeal Neoplasms; Male; Morpholines; Ondansetron; Quetiapine Fumarate

2012
Aprepitant: a novel neurokinin-1 receptor/substance P antagonist as antipruritic therapy in cutaneous T-cell lymphoma.
    Journal of the American Academy of Dermatology, 2012, Volume: 67, Issue:5

    Topics: Aged; Antipruritics; Aprepitant; Drug Therapy, Combination; Female; Humans; Interferon alpha-2; Interferon-alpha; Lymphoma, T-Cell, Cutaneous; Morpholines; Neurokinin-1 Receptor Antagonists; Ondansetron; Pain Measurement; Recombinant Proteins; Substance P

2012
A validated micellar electrokinetic chromatography method for the quantitation of dexamethasone, ondansetron and aprepitant, antiemetic drugs, in organogel.
    Journal of pharmaceutical and biomedical analysis, 2013, Volume: 86

    Topics: Antiemetics; Aprepitant; Chemistry, Pharmaceutical; Chromatography, Micellar Electrokinetic Capillary; Dexamethasone; Gels; Morpholines; Ondansetron

2013
Tranexamic acid induces kaolin intake stimulating a pathway involving tachykinin neurokinin 1 receptors in rats.
    European journal of pharmacology, 2014, Jan-15, Volume: 723

    Topics: Animals; Antiemetics; Antifibrinolytic Agents; Aprepitant; Area Postrema; Domperidone; Dopamine Antagonists; Kaolin; Male; Morpholines; Neurokinin-1 Receptor Antagonists; Ondansetron; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Receptors, Neurokinin-1; Serotonin Antagonists; Solitary Nucleus; Tranexamic Acid

2014
Complementarity of UV-PLS and HPLC for the simultaneous evaluation of antiemetic drugs.
    Talanta, 2014, Volume: 120

    Topics: Administration, Cutaneous; Antiemetics; Aprepitant; Chromatography, High Pressure Liquid; Dexamethasone; Gels; Least-Squares Analysis; Limit of Detection; Morpholines; Ondansetron; Spectrophotometry, Ultraviolet

2014
Automated analysis of delayed emesis in the telemetered ferret: detection of synergistic effects of aprepitant and ondansetron.
    Fundamental & clinical pharmacology, 2014, Volume: 28, Issue:6

    Topics: Animals; Antiemetics; Antineoplastic Agents; Aprepitant; Automation; Cisplatin; Drug Synergism; Ferrets; Male; Morpholines; Ondansetron; Telemetry; Time Factors; Vomiting

2014
CNS drug development: lessons from the development of ondansetron, aprepitant, ramelteon, varenicline, lorcaserin, and suvorexant. Part I.
    Journal of psychiatric practice, 2014, Volume: 20, Issue:6

    Topics: Aprepitant; Azepines; Benzazepines; Central Nervous System Agents; Drug Discovery; History, 20th Century; History, 21st Century; Humans; Indenes; Morpholines; Neurotransmitter Agents; Ondansetron; Quinoxalines; Triazoles; Varenicline

2014
Efficacy of granisetron and aprepitant in a patient who failed ondansetron in the prophylaxis of radiation induced nausea and vomiting: a case report.
    Annals of palliative medicine, 2015, Volume: 4, Issue:1

    Topics: Antiemetics; Aprepitant; Bone Neoplasms; Breast Neoplasms; Female; Granisetron; Humans; Middle Aged; Morpholines; Nausea; Neoplasm Metastasis; Ondansetron

2015
Palonosetron with aprepitant plus dexamethasone to prevent chemotherapy-induced nausea and vomiting during gemcitabine/cisplatin in urothelial cancer patients.
    International journal of urology : official journal of the Japanese Urological Association, 2015, Volume: 22, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Aprepitant; Carcinoma, Transitional Cell; Cisplatin; Deoxycytidine; Dexamethasone; Drug Therapy, Combination; Female; Gemcitabine; Granisetron; Humans; Isoquinolines; Kidney Neoplasms; Male; Middle Aged; Morpholines; Nausea; Ondansetron; Palonosetron; Quinuclidines; Retrospective Studies; Serotonin 5-HT3 Receptor Antagonists; Serotonin Antagonists; Ureteral Neoplasms; Urinary Bladder Neoplasms; Urologic Neoplasms; Vomiting

2015
[Effect of Ju-Pi-Tang on Cisplatin-induced Emetic Model in Minks].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2015, Volume: 38, Issue:2

    Topics: Animals; Antiemetics; Aprepitant; Brain; Cisplatin; Disease Models, Animal; Drugs, Chinese Herbal; Ileum; Mink; Morpholines; Ondansetron; Vomiting

2015
CLINICAL DECISIONS. Chemotherapy-Induced Nausea and Vomiting.
    The New England journal of medicine, 2016, Jul-14, Volume: 375, Issue:2

    Topics: Antiemetics; Antineoplastic Agents; Aprepitant; Benzodiazepines; Dexamethasone; Drug Therapy, Combination; Female; Humans; Middle Aged; Morpholines; Nausea; Olanzapine; Ondansetron; Vomiting

2016
Evaluation of Pentravan
    International journal of pharmaceutics, 2016, Dec-30, Volume: 515, Issue:1-2

    Topics: Administration, Cutaneous; Animals; Antiemetics; Antineoplastic Agents; Aprepitant; Chemistry, Pharmaceutical; Dexamethasone; Drug Carriers; Humans; Lecithins; Morpholines; Nausea; Ondansetron; Pharmaceutical Vehicles; Swine; Vomiting

2016
The Role of Aprepitant in Prevention of Postoperative Nausea and Vomiting After Bariatric Surgery.
    Obesity surgery, 2018, Volume: 28, Issue:1

    Topics: Adult; Aged; Antiemetics; Aprepitant; Bariatric Surgery; Chemoprevention; Dexamethasone; Double-Blind Method; Female; Humans; Male; Middle Aged; Morpholines; Obesity, Morbid; Ondansetron; Postoperative Nausea and Vomiting; Retrospective Studies

2018
Safety profile of HTX-019 administered as an intravenous push in cancer patients: a retrospective review.
    Expert opinion on drug safety, 2020, Volume: 19, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antiemetics; Antineoplastic Agents; Aprepitant; Dexamethasone; Drug Therapy, Combination; Female; Humans; Infusions, Intravenous; Injections, Intravenous; Male; Middle Aged; Nausea; Neoplasms; Neurokinin-1 Receptor Antagonists; Ondansetron; Palonosetron; Retrospective Studies; Vomiting

2020
Extrapolation of Adult Efficacy to Pediatric Patients With Chemotherapy-Induced Nausea and Vomiting.
    Journal of clinical pharmacology, 2020, Volume: 60, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antiemetics; Antineoplastic Agents; Aprepitant; Child; Child, Preschool; Clinical Trials as Topic; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Drug Dosage Calculations; Female; Granisetron; Humans; Infant; Male; Middle Aged; Nausea; Neurokinin-1 Receptor Antagonists; Ondansetron; Palonosetron; Treatment Outcome; United States; United States Food and Drug Administration; Vomiting; Young Adult

2020
Letter referencing "Randomized open-label phase II trial of 5-day aprepitant plus ondansetron compared to ondansetron alone in the prevention of chemotherapy-induced nausea-vomiting in glioma patients receiving adjuvant temozolomide".
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2020, Volume: 28, Issue:12

    Topics: Antineoplastic Agents; Aprepitant; Glioma; Humans; Nausea; Ondansetron; Temozolomide; Vomiting

2020
Response to the letter to the Editor concerning manuscript entitled, "Randomized open-label phase II trial of 5-day aprepitant plus ondansetron compared to ondansetron alone in the prevention of chemotherapy-induced nausea-vomiting (CINV) in glioma patien
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2020, Volume: 28, Issue:12

    Topics: Antineoplastic Agents; Aprepitant; Glioma; Humans; Nausea; Ondansetron; Temozolomide; Vomiting

2020
Impact of Emend on Perioperative Bariatric Surgery Antiemetic Utilization, Patient Satisfaction, and Costs.
    Surgical laparoscopy, endoscopy & percutaneous techniques, 2023, Jun-01, Volume: 33, Issue:3

    Topics: Antiemetics; Aprepitant; Bariatric Surgery; Humans; Ondansetron; Patient Satisfaction; Postoperative Nausea and Vomiting; Retrospective Studies

2023