Page last updated: 2024-09-04

omeprazole sulfone and dextromethorphan

omeprazole sulfone has been researched along with dextromethorphan in 2 studies

Compound Research Comparison

Studies
(omeprazole sulfone)
Trials
(omeprazole sulfone)
Recent Studies (post-2010)
(omeprazole sulfone)
Studies
(dextromethorphan)
Trials
(dextromethorphan)
Recent Studies (post-2010) (dextromethorphan)
5012172,020342593

Protein Interaction Comparison

ProteinTaxonomyomeprazole sulfone (IC50)dextromethorphan (IC50)
Sodium channel protein type 1 subunit alphaRattus norvegicus (Norway rat)1.3
Sodium channel protein type 2 subunit alphaRattus norvegicus (Norway rat)1.3
Sodium channel protein type 3 subunit alphaRattus norvegicus (Norway rat)1.3
Cytochrome P450 2D26Rattus norvegicus (Norway rat)5.6
Cytochrome P450 2D6Homo sapiens (human)2.1768
Sodium-dependent serotonin transporterHomo sapiens (human)0.0027
Sigma non-opioid intracellular receptor 1Cavia porcellus (domestic guinea pig)0.1236

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Isoherranen, N; Lutz, JD1
Aboagye, EO; Clarke, S; Edwards, RJ; Lee, P; Liddle, C; Lozan-Kuehne, JP; Maslen, L; Ramaswami, R; Sharma, R; Trousil, S1

Trials

1 trial(s) available for omeprazole sulfone and dextromethorphan

ArticleYear
Altered cytochrome 2E1 and 3A P450-dependent drug metabolism in advanced ovarian cancer correlates to tumour-associated inflammation.
    British journal of pharmacology, 2019, Volume: 176, Issue:18

    Topics: Adult; Aged; Aged, 80 and over; C-Reactive Protein; Caffeine; Chlorzoxazone; Cytochrome P-450 Enzyme System; Cytokines; Dextromethorphan; Female; Humans; Inflammation; Middle Aged; Omeprazole; Ovarian Neoplasms

2019

Other Studies

1 other study(ies) available for omeprazole sulfone and dextromethorphan

ArticleYear
Prediction of relative in vivo metabolite exposure from in vitro data using two model drugs: dextromethorphan and omeprazole.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1

    Topics: Dextromethorphan; Humans; Microsomes, Liver; Omeprazole; Predictive Value of Tests

2012