omeprazole sulfide has been researched along with omeprazole in 16 studies
| Studies (omeprazole sulfide) | Trials (omeprazole sulfide) | Recent Studies (post-2010) (omeprazole sulfide) | Studies (omeprazole) | Trials (omeprazole) | Recent Studies (post-2010) (omeprazole) |
|---|---|---|---|---|---|
| 25 | 0 | 12 | 9,085 | 2,737 | 1,487 |
| Protein | Taxonomy | omeprazole sulfide (IC50) | omeprazole (IC50) |
|---|---|---|---|
| Mcl-1 | Homo sapiens (human) | 3.1448 | |
| cGMP-specific 3',5'-cyclic phosphodiesterase | Homo sapiens (human) | 0.28 | |
| Potassium-transporting ATPase alpha chain 1 | Homo sapiens (human) | 1.45 | |
| Cytochrome P450 2C19 | Homo sapiens (human) | 2.315 | |
| Potassium-transporting ATPase subunit beta | Homo sapiens (human) | 1.45 | |
| WD repeat-containing protein 5 | Homo sapiens (human) | 1.7 | |
| Glutathione S-transferase omega-1 | Homo sapiens (human) | 4.6 | |
| Histone-lysine N-methyltransferase 2A | Homo sapiens (human) | 1.7 | |
| Muscarinic acetylcholine receptor | Cavia porcellus (domestic guinea pig) | 3.8 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (31.25) | 18.7374 |
| 1990's | 3 (18.75) | 18.2507 |
| 2000's | 3 (18.75) | 29.6817 |
| 2010's | 5 (31.25) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bergman, NA; Fryklund, J; Kühler, TC; Larsson, H; Lee, A; Weilitz, J | 1 |
| Carlton, DL; Collin-Smith, LJ; Daniels, AJ; Deaton, DN; Goetz, AS; Laudeman, CP; Littleton, TR; Morgan, RJ; Musso, DL; Szewczyk, JR; Zhang, C | 1 |
| Fryklund, J; Wallmark, B | 1 |
| Andersson, T; Bodemar, G; Larsson, R; Naesdal, J; Regårdh, CG; Skånberg, I; Walan, A | 1 |
| Jones, DB; Mihaly, GW; Morgan, DJ; Smallwood, RA; Webster, LK | 1 |
| Brändström, A; Larsson, H; Wallmark, B | 1 |
| Louis, WJ; Mihaly, GW; Prichard, PJ; Smallwood, RA; Yeomans, ND | 1 |
| Chiba, K; Ishizaki, T; Kobayashi, K; Kuroiwa, Y; Tani, M | 1 |
| Farrán, R; García-Encina, G; Martínez, L; Puig, S | 1 |
| Daujat-Chavanieu, M; Fabre, JM; Gerbal-Chaloin, S; Maurel, P; Pichard-Garcia, L; Poellinger, L; Sa-Cunha, A | 1 |
| Brown, KC; Kashuba, AD; Rezk, NL | 1 |
| Babiak, P; Hájíček, J; Kyslík, P; Kyslíková, E; Marešová, H; Palyzová, A; Stěpánek, V; Valešová, R | 1 |
| Boix, C; Hernández, F; Ibáñez, M; Niessen, WM; Sancho, JV | 1 |
| Dorado, RM; Nevado, JJ; Peñalvo, GC; Robledo, VR | 1 |
| Blanazs, A; Bristow, TW; Coombes, SR; Corry, T; Nunn, M; Ray, AD | 1 |
| Ahn, T; Doan, TT; Jang, HH; Kang, CK; Kang, HS; Kim, DH; Le, TK; Nguyen, TH; Park, KD; Ryu, SH; Yim, DE; Yun, CH | 1 |
16 other study(ies) available for omeprazole sulfide and omeprazole
| Article | Year |
|---|---|
Structure-activity relationship of omeprazole and analogues as Helicobacter pylori urease inhibitors.
Topics: Ammonia; Animals; Anti-Bacterial Agents; Anti-Ulcer Agents; Benzamides; Binding Sites; Cysteine; Drug Design; Enzyme Inhibitors; Helicobacter pylori; Hydrogen-Ion Concentration; Mercaptoethanol; Mice; Mice, Inbred Strains; Omeprazole; Structure-Activity Relationship; Urease | 1995 |
Discovery of small molecule agonists for the bombesin receptor subtype 3 (BRS-3) based on an omeprazole lead.
Topics: Baculoviridae; Benzimidazoles; Brain; Chemistry, Pharmaceutical; Chlorofluorocarbons, Methane; Drug Design; Drug Evaluation, Preclinical; Humans; Kinetics; Models, Chemical; Omeprazole; Pyridines; Receptors, Bombesin; Sulfides | 2008 |
Sulfide and sulfoxide derivatives of substituted benzimidazoles inhibit acid formation in isolated gastric glands by different mechanisms.
Topics: Adenosine Triphosphatases; Aminopyrine; Animals; Benzimidazoles; Gastric Acid; Gastric Mucosa; H(+)-K(+)-Exchanging ATPase; In Vitro Techniques; Male; Mercaptoethanol; Omeprazole; Oxygen Consumption; Rabbits; Sulfides; Sulfoxides | 1986 |
Pharmacokinetics of [14C]omeprazole in patients with impaired renal function.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Benzimidazoles; Blood Proteins; Female; Humans; Kidney Failure, Chronic; Kinetics; Male; Mathematics; Middle Aged; Omeprazole | 1986 |
Effect of hypoxia on oxidative and reductive pathways of omeprazole metabolism by the isolated perfused rat liver.
Topics: Animals; Benzimidazoles; Hypoxia; Lactates; Lactic Acid; Liver; Male; Omeprazole; Oxidation-Reduction; Oxygen; Perfusion; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1985 |
Evidence for acid-induced transformation of omeprazole into an active inhibitor of (H+ + K+)-ATPase within the parietal cell.
Topics: Adenosine Triphosphatases; Aminopyrine; Animals; Benzimidazoles; Dithiothreitol; Female; Gastric Acid; Gastric Mucosa; Glutathione; Guinea Pigs; H(+)-K(+)-Exchanging ATPase; Hydrogen-Ion Concentration; Male; Mathematics; Mercaptoethanol; Omeprazole; Parietal Cells, Gastric; Rabbits | 1984 |
Simultaneous high-performance liquid chromatographic analysis of omeprazole and its sulphone and sulphide metabolites in human plasma and urine.
Topics: Adult; Benzimidazoles; Chromatography, High Pressure Liquid; Humans; Kinetics; Male; Omeprazole; Tablets, Enteric-Coated | 1983 |
Development and preliminary application of a high-performance liquid chromatographic assay for omeprazole metabolism in human liver microsomes.
Topics: Chromatography, High Pressure Liquid; Humans; Microsomes, Liver; Omeprazole; Proton Pumps; Reproducibility of Results | 1994 |
Validation of an automated liquid chromatographic method for omeprazole in human plasma using on-line solid-phase extraction.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Automation; Chromatography, High Pressure Liquid; Drug Stability; Flow Injection Analysis; Humans; Omeprazole; Quality Control; Reproducibility of Results | 1999 |
Role of CYP3A4 in the regulation of the aryl hydrocarbon receptor by omeprazole sulphide.
Topics: Active Transport, Cell Nucleus; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cells, Cultured; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Genes, Reporter; Hepatocytes; Humans; Liver Neoplasms; Mice; Omeprazole; Polychlorinated Dibenzodioxins; Pregnane X Receptor; Receptors, Aryl Hydrocarbon; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; RNA, Messenger | 2006 |
A simple and sensitive bioanalytical assay for simultaneous determination of omeprazole and its three major metabolites in human blood plasma using RP-HPLC after a simple liquid-liquid extraction procedure.
Topics: Chromatography, High Pressure Liquid; Drug Stability; Humans; Molecular Structure; Omeprazole; Reproducibility of Results | 2006 |
Whole-cell oxidation of omeprazole sulfide to enantiopure esomeprazole with Lysinibacillus sp. B71.
Topics: Bacillus; Base Sequence; Bioreactors; Biotransformation; Chromatography, Thin Layer; Culture Media; DNA Primers; Esomeprazole; Hydrogen-Ion Concentration; Omeprazole; Oxidation-Reduction; Polymerase Chain Reaction; Stereoisomerism; Temperature | 2011 |
Investigating the presence of omeprazole in waters by liquid chromatography coupled to low and high resolution mass spectrometry: degradation experiments.
Topics: Anti-Ulcer Agents; Chromatography, Liquid; Environmental Monitoring; Hydrolysis; Light; Omeprazole; Photolysis; Tandem Mass Spectrometry; Ultraviolet Rays; Water; Water Pollutants, Chemical | 2013 |
Simultaneous determination of omeprazole and their main metabolites in human urine samples by capillary electrophoresis using electrospray ionization-mass spectrometry detection.
Topics: Chromatography, High Pressure Liquid; Electrophoresis, Capillary; Humans; Omeprazole; Spectrometry, Mass, Electrospray Ionization | 2014 |
Coupling and optimisation of online nuclear magnetic resonance spectroscopy and mass spectrometry for process monitoring to cover the broad range of process concentration.
Topics: Calibration; Chromatography, High Pressure Liquid; Magnetic Resonance Spectroscopy; Mass Spectrometry; Omeprazole | 2017 |
Regioselective C-H hydroxylation of omeprazole sulfide by Bacillus megaterium CYP102A1 to produce a human metabolite.
Topics: Bacillus megaterium; Bacterial Proteins; Catalysis; Cytochrome P-450 Enzyme System; Humans; Hydroxylation; NADPH-Ferrihemoprotein Reductase; Omeprazole; Stereoisomerism | 2017 |