Compounds > omeprazole

omeprazole and voriconazole

omeprazole has been researched along with voriconazole in 14 studies

Research

Studies (14)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	3 (21.43)	29.6817
2010's	7 (50.00)	24.3611
2020's	4 (28.57)	2.80

Authors

Authors	Studies
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY	1
Lombardo, F; Obach, RS; Waters, NJ	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Chen, F; Chen, W; Lan, L; Li, B; Li, J; Liu, Y; Mao, F; Ni, S; Wei, H; Zhu, J	1
Hamlin, J; Kleinermans, D; Layton, G; Nichols, D; Purkins, L; Tan, K; Wood, N	1
Bhavan, KP; Boyd, NK; Swancutt, MA; Zoellner, CL	1
Chayakulkeeree, M; Maneerattanaporn, M; Poovipirom, N; Siengwattana, P	1
Akers, KS; Boyd, NK; Niece, KL	1
Barbeito Castiñeiras, G; Bardán García, B; Belles Medall, D; Blanco Dorado, S; Blanco Hortas, A; Campos-Toimil, M; Carracedo, Á; Fernández-Ferreiro, A; Gómez Márquez, A; Lamas, MJ; Latorre-Pellicer, A; López-Vizcaíno, A; Maroñas Amigo, O; Otero Espinar, F; Pérez Del Molino Bernal, ML; Rodríguez Jato, MT; Zarra Ferro, I	1
Ding, H; Hu, L; Huang, Q; Jiang, Y; Liu, Q; Liu, S; Yin, T	1
Chenel, M; Gautier-Veyret, E; Payen, L; Simon, F; Stanke-Labesque, F; Tod, M; Truffot, A	1
Hsu, AJ; Lee, CKK; McAteer, J; Tamma, PD; Zhang, SX	1

Reviews

1 review(s) available for omeprazole and voriconazole

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

1 trial(s) available for omeprazole and voriconazole

Article	Year
Effect of omeprazole on the steady-state pharmacokinetics of voriconazole. British journal of clinical pharmacology, 2003, Volume: 56 Suppl 1 Topics: Administration, Oral; Adult; Anti-Ulcer Agents; Antifungal Agents; Cross-Over Studies; Drug Combinations; Drug Interactions; Humans; Male; Omeprazole; Pyrimidines; Triazoles; Voriconazole	2003

Other Studies

12 other study(ies) available for omeprazole and voriconazole

Article	Year
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics. Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5 Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution	2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Novel Terminal Bipheny-Based Diapophytoene Desaturases (CrtN) Inhibitors as Anti-MRSA/VISR/LRSA Agents with Reduced hERG Activity. Journal of medicinal chemistry, 2018, 01-11, Volume: 61, Issue:1 Topics: Animals; Drug Design; Enzyme Inhibitors; ERG1 Potassium Channel; HEK293 Cells; Hep G2 Cells; Humans; Inhibitory Concentration 50; Methicillin-Resistant Staphylococcus aureus; Mice; Oxidoreductases; Rats; Safety; Solubility; Structure-Activity Relationship; Water	2018
Utilization of omeprazole to augment subtherapeutic voriconazole concentrations for treatment of Aspergillus infections. Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:11 Topics: Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Brain; Drug Administration Routes; Drug Administration Schedule; Drug Monitoring; Drug Synergism; Humans; Magnetic Resonance Imaging; Male; Omeprazole; Pyrimidines; Triazoles; Voriconazole; Young Adult	2012
Effect of proton pump inhibitor on plasma voriconazole concentration in Thai patients. Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2015, Volume: 98, Issue:3 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antifungal Agents; Aspergillosis; Dose-Response Relationship, Drug; Drug Interactions; Drug Monitoring; Female; Humans; Male; Middle Aged; Mycoses; Omeprazole; Prospective Studies; Proton Pump Inhibitors; Thailand; Voriconazole; Young Adult	2015
In vitro study of the variable effects of proton pump inhibitors on voriconazole. Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:9 Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Antifungal Agents; Cytochrome P-450 CYP2C19; Cytochrome P-450 Enzyme System; Drug Interactions; Esomeprazole; Humans; Lansoprazole; Microsomes, Liver; Omeprazole; Pantoprazole; Proton Pump Inhibitors; Rabeprazole; Voriconazole	2015
A multicentre prospective study evaluating the impact of proton-pump inhibitors omeprazole and pantoprazole on voriconazole plasma concentrations. British journal of clinical pharmacology, 2020, Volume: 86, Issue:8 Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Drug Interactions; Enzyme Inhibitors; Esomeprazole; Humans; Omeprazole; Pantoprazole; Prospective Studies; Proton Pump Inhibitors; Voriconazole	2020
Effect of proton pump inhibitors on voriconazole concentrations in Chinese patients with malignant hematological diseases. European journal of clinical pharmacology, 2020, Volume: 76, Issue:6 Topics: Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Drug Interactions; Female; Humans; Lansoprazole; Male; Molecular Docking Simulation; Omeprazole; Pantoprazole; Proton Pump Inhibitors; Retrospective Studies; Voriconazole	2020
Modeling Approach to Predict the Impact of Inflammation on the Pharmacokinetics of CYP2C19 and CYP3A4 Substrates. Pharmaceutical research, 2021, Volume: 38, Issue:3 Topics: Antifungal Agents; Computer Simulation; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Drug Interactions; Humans; Inflammation; Midazolam; Models, Biological; Omeprazole; Voriconazole	2021
Boosting of Voriconazole Levels With Omeprazole, A CYP450 2C19 Inhibitor. The Pediatric infectious disease journal, 2023, 06-01, Volume: 42, Issue:6 Topics: Adult; Antifungal Agents; Child; Child, Preschool; Female; Genotype; Humans; Omeprazole; Voriconazole	2023