omeprazole has been researched along with ritonavir in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 14 (53.85) | 29.6817 |
| 2010's | 11 (42.31) | 24.3611 |
| 2020's | 1 (3.85) | 2.80 |
| Authors | Studies |
|---|---|
| Li, Y; Li, YH; Wang, YH; Yang, L; Yang, SL | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M | 1 |
| Greenblatt, DJ; Hesse, LM; Shader, RI; Venkatakrishnan, K; von Moltke, LL | 1 |
| Crum, NF; Furtek, KJ; Olson, PE; Wallace, MR | 1 |
| Chan-Tack, KM; Edozien, A | 1 |
| Baxter-Meheux, F; Blake, MJ; Eron, JJ; Gaver, VE; Kashuba, AD; Klein, CE; Patterson, KB; Rezk, NL; Rublein, JC; Yeh, RF | 1 |
| Back, D; Boffito, M; Fletcher, C; Gazzard, B; Pozniak, AL; Robinson, L; Schutz, M; Tolowinska, I; Unsworth, J; Winston, A | 1 |
| Ballard, C; Best, B; Caperna, J; Capparelli, E; Goicoechea, M; Haubrich, R | 1 |
| De Marez, T; De Paepe, E; De Pauw, M; Hoetelmans, RM; Lefebvre, E; Parys, W; Sekar, VJ | 1 |
| Back, D; Boffito, M; Chaikan, A; Dickinson, L; Fletcher, C; Gazzard, B; Herath, D; Moyle, G; Nelson, M; Pozniak, A; Singh, K | 1 |
| Donovan, BJ; Hollowell, SB; Kashuba, AD; Min, SS; Raasch, RH; Rezk, NL; Rublein, JC; Smith, PC; Tallman, MN; Tappouni, HL; Theodore, D; Tien, HC | 1 |
| Beck, K; Cai, Y; Causemaker, SJ; Chiu, YL; Doan, T; Esslinger, HU; Hanna, GJ; King, KR; Klein, CE; Podsadecki, TJ | 1 |
| Acosta, EP; Kim, G; Klebert, M; Mondy, KE; Overton, ET; Rodriguez, M; Royal, M; Spitz, T; Tschampa, JM | 1 |
| Agarwala, S; Bertz, R; Dragone, J; Eley, T; Li, T; Mahnke, L; Persson, A; Xu, X; Zhu, L | 1 |
| Bech, N; Brennan, BJ; Morcos, PN; Moreira, SA; Navarro, MT; Quatkemeyer, A; Smith, PF | 1 |
| Adkison, KK; Gan, J; Jones, LS; Lou, Y; Wilfret, DA | 1 |
| Awni, WM; Dutta, S; Hu, B; Menon, RM; Podsadecki, TJ; Polepally, AR | 1 |
1 review(s) available for omeprazole and ritonavir
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
8 trial(s) available for omeprazole and ritonavir
| Article | Year |
|---|---|
Pharmacokinetic interaction between darunavir boosted with ritonavir and omeprazole or ranitidine in human immunodeficiency virus-negative healthy volunteers.
Topics: Adolescent; Adult; Anti-HIV Agents; Anti-Ulcer Agents; Antiviral Agents; Area Under Curve; Darunavir; Drug Interactions; Female; Histamine H2 Antagonists; Humans; Male; Middle Aged; Omeprazole; Ranitidine; Ritonavir; Sulfonamides | 2007 |
Pharmacokinetics and safety of saquinavir/ritonavir and omeprazole in HIV-infected subjects.
Topics: Adult; Cross-Over Studies; Drug Interactions; Drug Therapy, Combination; Female; Headache; HIV Infections; HIV-1; Humans; Male; Middle Aged; Omeprazole; Ritonavir; Saquinavir | 2008 |
Effect of omeprazole on the plasma concentrations of indinavir when administered alone and in combination with ritonavir.
Topics: Adolescent; Adult; Anti-Ulcer Agents; Area Under Curve; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Female; HIV Protease Inhibitors; Humans; Indinavir; Male; Middle Aged; Omeprazole; Ritonavir | 2008 |
Effects of acid-reducing agents on the pharmacokinetics of lopinavir/ritonavir and ritonavir-boosted atazanavir.
Topics: Adult; Anti-HIV Agents; Anti-Ulcer Agents; Area Under Curve; Atazanavir Sulfate; Biological Availability; Dose-Response Relationship, Drug; Drug Interactions; Female; Histamine H2 Antagonists; HIV Protease Inhibitors; Humans; Lopinavir; Male; Middle Aged; Oligopeptides; Omeprazole; Pyridines; Pyrimidinones; Ranitidine; Ritonavir | 2008 |
Effect of low-dose omeprazole (20 mg daily) on the pharmacokinetics of multiple-dose atazanavir with ritonavir in healthy subjects.
Topics: Adult; Antiretroviral Therapy, Highly Active; Area Under Curve; Atazanavir Sulfate; Cohort Studies; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Female; HIV Infections; HIV Protease Inhibitors; Humans; Male; Oligopeptides; Omeprazole; Proton Pump Inhibitors; Pyridines; Ritonavir | 2011 |
Effect of meal and antisecretory agents on the pharmacokinetics of danoprevir/ritonavir in healthy volunteers.
Topics: Adult; Area Under Curve; Cross-Over Studies; Cyclopropanes; Female; Food-Drug Interactions; Healthy Volunteers; Humans; Isoindoles; Lactams; Lactams, Macrocyclic; Male; Meals; Neuropeptides; Omeprazole; Proline; Ranitidine; Ritonavir; Sulfonamides; Young Adult | 2014 |
Effects of omeprazole and ritonavir on absorption and elimination of the hepatitis C virus NS5A inhibitor GSK2336805 in healthy adults.
Topics: Adolescent; Adult; Aged; Antiviral Agents; Area Under Curve; Biotransformation; Carbamates; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Female; Gastrointestinal Absorption; Half-Life; Healthy Volunteers; Hepacivirus; Humans; Male; Metabolic Clearance Rate; Middle Aged; New York; Omeprazole; Protease Inhibitors; Proton Pump Inhibitors; Ritonavir; Valine; Viral Nonstructural Proteins; Young Adult | 2014 |
Drug-Drug Interaction of Omeprazole With the HCV Direct-Acting Antiviral Agents Paritaprevir/Ritonavir and Ombitasvir With and Without Dasabuvir.
Topics: 2-Naphthylamine; Adult; Anilides; Anti-Ulcer Agents; Antiviral Agents; Area Under Curve; Carbamates; Cyclopropanes; Cytochrome P-450 CYP2C19; Drug Interactions; Drug Therapy, Combination; Female; Humans; Lactams, Macrocyclic; Macrocyclic Compounds; Male; Omeprazole; Proline; Ritonavir; Sulfonamides; Uracil; Valine | 2016 |
17 other study(ies) available for omeprazole and ritonavir
| Article | Year |
|---|---|
Modeling K(m) values using electrotopological state: substrates for cytochrome P450 3A4-mediated metabolism.
Topics: Computational Biology; Cyclohexanols; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Molecular Structure; Principal Component Analysis; Pyrrolizidine Alkaloids; Quantitative Structure-Activity Relationship; Reproducibility of Results; Substrate Specificity; Venlafaxine Hydrochloride | 2005 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries | 2023 |
CYP3A4 is the major CYP isoform mediating the in vitro hydroxylation and demethylation of flunitrazepam.
Topics: Anti-Anxiety Agents; Benzoflavones; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Flunitrazepam; Humans; Hydroxylation; Isoenzymes; Ketoconazole; Kinetics; Methylation; Microsomes, Liver; Mixed Function Oxygenases; Omeprazole; Quinidine; Ritonavir; Sulfaphenazole; Transfection | 2001 |
FDA notifications. BMS issues letter about omeprazole.
Topics: Area Under Curve; Atazanavir Sulfate; Drug Industry; Drug Interactions; HIV Infections; HIV Protease Inhibitors; Oligopeptides; Omeprazole; Pyridines; Randomized Controlled Trials as Topic; Ritonavir; United States; United States Food and Drug Administration | 2005 |
Proton pump inhibitor therapy in atazanavir-treated patients: contraindicated?
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Antacids; Antiretroviral Therapy, Highly Active; Atazanavir Sulfate; Benzimidazoles; Contraindications; Drug Interactions; HIV Infections; HIV Protease Inhibitors; Humans; Oligopeptides; Omeprazole; Proton Pump Inhibitors; Pyridines; Rabeprazole; Ritonavir | 2006 |
Ritonavir-boosted atazanavir may be efficacious in HIV-infected patients concurrently receiving omeprazole.
Topics: Atazanavir Sulfate; Drug Interactions; Drug Therapy, Combination; HIV Infections; Humans; Male; Middle Aged; Oligopeptides; Omeprazole; Pyridines; Ritonavir | 2006 |
Lopinavir/ritonavir induces the hepatic activity of cytochrome P450 enzymes CYP2C9, CYP2C19, and CYP1A2 but inhibits the hepatic and intestinal activity of CYP3A as measured by a phenotyping drug cocktail in healthy volunteers.
Topics: Administration, Oral; Adolescent; Adult; Aryl Hydrocarbon Hydroxylases; Biomarkers; Caffeine; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Therapy, Combination; Enzyme Induction; Female; HIV Protease Inhibitors; HIV Seronegativity; Humans; Injections, Intravenous; Intestinal Mucosa; Intestines; Liver; Lopinavir; Male; Midazolam; Middle Aged; Mixed Function Oxygenases; Omeprazole; Pyrimidinones; Ritonavir; Substrate Specificity; Warfarin | 2006 |
Effect of omeprazole on the pharmacokinetics of saquinavir-500 mg formulation with ritonavir in healthy male and female volunteers.
Topics: Adolescent; Adult; Anti-Ulcer Agents; Drug Interactions; Drug Therapy, Combination; Female; HIV Protease Inhibitors; Humans; Male; Middle Aged; Omeprazole; Proton Pump Inhibitors; Ritonavir; Saquinavir | 2006 |
Therapeutic ritonavir-boosted atazanavir plasma concentration and concurrent omeprazole use.
Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Atazanavir Sulfate; Drug Interactions; Drug Monitoring; HIV Infections; Humans; Male; Middle Aged; Oligopeptides; Omeprazole; Proton Pump Inhibitors; Pyridines; Ritonavir | 2006 |
The effect of acid reduction with a proton pump inhibitor on the pharmacokinetics of lopinavir or ritonavir in HIV-infected patients on lopinavir/ritonavir-based therapy.
Topics: Adult; Antiretroviral Therapy, Highly Active; Drug Interactions; Female; HIV Infections; HIV Protease Inhibitors; Humans; Lopinavir; Male; Middle Aged; Omeprazole; Proton Pump Inhibitors; Pyrimidinones; Ritonavir; Young Adult | 2010 |