omeprazole and lansoprazole sulfone

omeprazole has been researched along with lansoprazole sulfone in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (20.00)18.2507
2000's12 (80.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Goldstein, JA; Parkinson, A; Pearce, RE; Rodrigues, AD1
Ishizaki, T; Kim, HK; Kwon, JT; Sohn, DR1
Arimori, K; Fujii, J; Masa, K; Miyamoto, S; Nakano, M; Nakayama, T1
Arimori, K; Fujii, J; Hamada, A; Masa, K; Nakano, M1
Arimori, K; Hamada, A; Katsuki, H; Nakamura, C; Nakano, M2
Echizen, H; Nachi, S; Ohnishi, A; Ushiama, H1
Ali, E; Bandyopadhyay, U; Banerjee, RK; Biswas, K; Chattopadhyay, I; Varadaraj, A1
Miura, M; Suzuki, T; Tada, H1
Miura, M; Sugawara, K; Suzuki, T; Tada, H; Tateishi, T; Uno, T; Yasui-Furukori, N2
Saito, M; Sugawara, K; Takahata, T; Tateishi, T; Uno, T; Yasui-Furukori, N1
Sugawara, K; Takahata, T; Tateishi, T; Uno, T; Yasui-Furukori, N1
Munakata, A; Saito, M; Sugawara, K; Takahata, T; Tateishi, T; Uno, T; Yasui-Furukori, N1
Kagaya, H; Miura, M; Suzuki, T; Tada, H; Tateishi, T; Uno, T; Yasui-Furukori, N1

Trials

7 trial(s) available for omeprazole and lansoprazole sulfone

ArticleYear
Metabolic disposition of lansoprazole in relation to the S-mephenytoin 4'-hydroxylation phenotype status.
    Clinical pharmacology and therapeutics, 1997, Volume: 61, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Adult; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2C19; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Humans; Hydroxylation; Korea; Lansoprazole; Male; Mephenytoin; Mixed Function Oxygenases; Omeprazole; Phenotype; Polymorphism, Genetic; Proton Pump Inhibitors

1997
Dose-dependent inhibition of CYP3A activity by clarithromycin during Helicobacter pylori eradication therapy assessed by changes in plasma lansoprazole levels and partial cortisol clearance to 6beta-hydroxycortisol.
    Clinical pharmacology and therapeutics, 2002, Volume: 72, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Amoxicillin; Anti-Bacterial Agents; Aryl Hydrocarbon Hydroxylases; Clarithromycin; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Female; Helicobacter Infections; Helicobacter pylori; Humans; Hydrocortisone; Lansoprazole; Liver Function Tests; Male; Middle Aged; Omeprazole; Oxidoreductases, N-Demethylating; Penicillins; Protein Synthesis Inhibitors

2002
Pharmacokinetic differences between the enantiomers of lansoprazole and its metabolite, 5-hydroxylansoprazole, in relation to CYP2C19 genotypes.
    European journal of clinical pharmacology, 2004, Volume: 60, Issue:9

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Adult; Anti-Ulcer Agents; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C19; Dexlansoprazole; Female; Genotype; Half-Life; Humans; Lansoprazole; Male; Mixed Function Oxygenases; Omeprazole; Proton Pump Inhibitors; Stereoisomerism; Time Factors

2004
Effects of fluvoxamine on lansoprazole pharmacokinetics in relation to CYP2C19 genotypes.
    Journal of clinical pharmacology, 2004, Volume: 44, Issue:11

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Ulcer Agents; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Cross-Over Studies; Cytochrome P-450 CYP2C19; Double-Blind Method; Drug Synergism; Female; Fluvoxamine; Genotype; Humans; Lansoprazole; Male; Mixed Function Oxygenases; Omeprazole; Proton Pump Inhibitors; Selective Serotonin Reuptake Inhibitors

2004
Effects of clarithromycin on lansoprazole pharmacokinetics between CYP2C19 genotypes.
    British journal of clinical pharmacology, 2005, Volume: 59, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Adult; Analysis of Variance; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Clarithromycin; Cross-Over Studies; Cytochrome P-450 CYP2C19; Double-Blind Method; Drug Interactions; Enzyme Inhibitors; Female; Genotype; Heterozygote; Homozygote; Humans; Lansoprazole; Male; Mixed Function Oxygenases; Omeprazole; Protein Synthesis Inhibitors; Proton Pump Inhibitors

2005
Enantioselective disposition of lansoprazole in relation to CYP2C19 genotypes in the presence of fluvoxamine.
    British journal of clinical pharmacology, 2005, Volume: 60, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Cross-Over Studies; Cytochrome P-450 CYP2C19; Dexlansoprazole; Double-Blind Method; Drug Interactions; Enzyme Inhibitors; Female; Fluvoxamine; Genotype; Humans; Lansoprazole; Male; Mixed Function Oxygenases; Omeprazole

2005
Intestinal CYP3A4 is not involved in the enantioselective disposition of lansoprazole.
    Xenobiotica; the fate of foreign compounds in biological systems, 2006, Volume: 36, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Adult; Beverages; Citrus paradisi; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dexlansoprazole; Female; Humans; Intestines; Lansoprazole; Male; Metabolic Clearance Rate; Middle Aged; Omeprazole; Stereoisomerism

2006

Other Studies

8 other study(ies) available for omeprazole and lansoprazole sulfone

ArticleYear
Identification of the human P450 enzymes involved in lansoprazole metabolism.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 277, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Ulcer Agents; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Humans; Isoenzymes; Lansoprazole; Microsomes, Liver; Omeprazole; Rats; Recombinant Proteins

1996
Effect of clarithromycin and other macrolides on the sulfoxidation and 5-hydroxylation of lansoprazole in dogs.
    Biological & pharmaceutical bulletin, 1999, Volume: 22, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Dogs; Drug Interactions; Hydroxylation; In Vitro Techniques; Lansoprazole; Male; Microsomes, Liver; Omeprazole

1999
Pharmacokinetic differences between lansoprazole enantiomers and contribution of cytochrome P450 isoforms to enantioselective metabolism of lansoprazole in dogs.
    Biological & pharmaceutical bulletin, 2001, Volume: 24, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Area Under Curve; Biotransformation; Cytochrome P-450 Enzyme System; Dogs; Drug Interactions; Enzyme Inhibitors; Half-Life; In Vitro Techniques; Isoenzymes; Lansoprazole; Male; Microsomes, Liver; Omeprazole; Protein Binding; Proton Pump Inhibitors; Stereoisomerism

2001
High-performance liquid chromatographic assay for the simultaneous determination of lansoprazole enantiomers and metabolites in human liver microsomes.
    Journal of chromatography. B, Biomedical sciences and applications, 2001, Jun-05, Volume: 757, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Calibration; Chromatography, High Pressure Liquid; Humans; Lansoprazole; Microsomes, Liver; Omeprazole; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Stereoisomerism

2001
Role of CYP3A4 and CYP2C19 in the stereoselective metabolism of lansoprazole by human liver microsomes.
    European journal of clinical pharmacology, 2001, Volume: 57, Issue:10

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aryl Hydrocarbon Hydroxylases; Biotransformation; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Humans; Hydroxylation; In Vitro Techniques; Lansoprazole; Microsomes, Liver; Mixed Function Oxygenases; Omeprazole; Protein Isoforms; Proton Pump Inhibitors; Stereoisomerism

2001
A novel antioxidant and antiapoptotic role of omeprazole to block gastric ulcer through scavenging of hydroxyl radical.
    The Journal of biological chemistry, 2003, Mar-28, Volume: 278, Issue:13

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Antioxidants; Apoptosis; DNA Damage; Free Radical Scavengers; Hydroxyl Radical; Lansoprazole; Omeprazole; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Electrospray Ionization; Stomach Ulcer

2003
Simultaneous determination of lansoprazole enantiomers and their metabolites in plasma by liquid chromatography with solid-phase extraction.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2004, May-25, Volume: 804, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Chromatography, High Pressure Liquid; Humans; Kidney Transplantation; Lansoprazole; Omeprazole; Proton Pump Inhibitors; Reproducibility of Results; Sensitivity and Specificity; Stereoisomerism

2004
Determination of lansoprazole and two of its metabolites by liquid-liquid extraction and automated column-switching high-performance liquid chromatography: application to measuring CYP2C19 activity.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2005, Feb-25, Volume: 816, Issue:1-2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Chromatography, High Pressure Liquid; Female; Humans; Lansoprazole; Male; Omeprazole; Reproducibility of Results; Sensitivity and Specificity; Sulfones

2005