omeprazole and hypericum

omeprazole has been researched along with hypericum in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (75.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kleeberg, U; Krusekopf, S; Roots, I1
Abd El-Aty, AM; Li, T; Liu, J; Wang, D; Wang, JG; Wang, LS; Wu, J; Yang, TL; Zhong, XY; Zhou, G; Zhou, HH; Zhu, B1
Xie, HG1
Dostalek, M; Jurica, J; Pistovcakova, J; Sulcova, A; Tomandl, J1

Trials

1 trial(s) available for omeprazole and hypericum

ArticleYear
St John's wort induces both cytochrome P450 3A4-catalyzed sulfoxidation and 2C19-dependent hydroxylation of omeprazole.
    Clinical pharmacology and therapeutics, 2004, Volume: 75, Issue:3

    Topics: Adolescent; Adult; Analysis of Variance; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Catalysis; Cross-Over Studies; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Humans; Hydroxylation; Hypericum; Male; Mixed Function Oxygenases; Omeprazole; Plant Extracts; Sulfoxides

2004

Other Studies

3 other study(ies) available for omeprazole and hypericum

ArticleYear
Differential drug-induced mRNA expression of human CYP3A4 compared to CYP3A5, CYP3A7 and CYP3A43.
    European journal of pharmacology, 2003, Apr-11, Volume: 466, Issue:1-2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aryl Hydrocarbon Hydroxylases; Benzimidazoles; Cell Line, Tumor; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Gene Expression Regulation; Humans; Hypericum; Lansoprazole; Omeprazole; Pantoprazole; Plant Preparations; Rabeprazole; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfoxides

2003
Additional discussions regarding the altered metabolism and transport of omeprazole after long-term use of St John's wort.
    Clinical pharmacology and therapeutics, 2005, Volume: 78, Issue:4

    Topics: Anti-Ulcer Agents; Aryl Hydrocarbon Hydroxylases; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Biological Transport; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Antagonism; Enzyme Induction; Genotype; Humans; Hypericum; Mixed Function Oxygenases; Omeprazole; Plant Preparations

2005
The effect of St John's wort (hypericum perforatum) on cytochrome p450 1a2 activity in perfused rat liver.
    Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia, 2011, Volume: 155, Issue:3

    Topics: Animals; Benzoflavones; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Enzyme Inhibitors; Hypericum; In Vitro Techniques; Liver; Male; Omeprazole; Plant Extracts; Rats; Rats, Wistar

2011