omeprazole has been researched along with hypericum in 4 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kleeberg, U; Krusekopf, S; Roots, I | 1 |
| Abd El-Aty, AM; Li, T; Liu, J; Wang, D; Wang, JG; Wang, LS; Wu, J; Yang, TL; Zhong, XY; Zhou, G; Zhou, HH; Zhu, B | 1 |
| Xie, HG | 1 |
| Dostalek, M; Jurica, J; Pistovcakova, J; Sulcova, A; Tomandl, J | 1 |
1 trial(s) available for omeprazole and hypericum
| Article | Year |
|---|---|
St John's wort induces both cytochrome P450 3A4-catalyzed sulfoxidation and 2C19-dependent hydroxylation of omeprazole.
Topics: Adolescent; Adult; Analysis of Variance; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Catalysis; Cross-Over Studies; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Humans; Hydroxylation; Hypericum; Male; Mixed Function Oxygenases; Omeprazole; Plant Extracts; Sulfoxides | 2004 |
3 other study(ies) available for omeprazole and hypericum
| Article | Year |
|---|---|
Differential drug-induced mRNA expression of human CYP3A4 compared to CYP3A5, CYP3A7 and CYP3A43.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aryl Hydrocarbon Hydroxylases; Benzimidazoles; Cell Line, Tumor; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Gene Expression Regulation; Humans; Hypericum; Lansoprazole; Omeprazole; Pantoprazole; Plant Preparations; Rabeprazole; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfoxides | 2003 |
Additional discussions regarding the altered metabolism and transport of omeprazole after long-term use of St John's wort.
Topics: Anti-Ulcer Agents; Aryl Hydrocarbon Hydroxylases; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Biological Transport; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Antagonism; Enzyme Induction; Genotype; Humans; Hypericum; Mixed Function Oxygenases; Omeprazole; Plant Preparations | 2005 |
The effect of St John's wort (hypericum perforatum) on cytochrome p450 1a2 activity in perfused rat liver.
Topics: Animals; Benzoflavones; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Enzyme Inhibitors; Hypericum; In Vitro Techniques; Liver; Male; Omeprazole; Plant Extracts; Rats; Rats, Wistar | 2011 |